... replication induces potent expression of chemokines, so the epithelium is postulated to be a primary initiator of pulmonary inflammation in RSV infections [3] The presence of eosinophil cationic ... with RSV at moi 3, and then INF-a was added into culture atthe indicated time points at a final concentration of 1000 U/mL for 30 Un-infected cells were treated with IFN-a at time 0, and so on ... [5,23,24] These are a superfamily of small chemotactic cytokines, which regulate the migration and activation of leukocytes and play a key role in inflammatory and infectious processes ofthe lung...
... Numbers in vertical framed arrows indicate the position ofthe introns The boxes indicate amino-acid substitutions skipping of three successive exons during the course ofthe processing ofthe primary ... components e and d seem to be in common with the A variant Therefore, band b represents the only component specific to the M variant The intensities ofthe bands inthe MF pattern indicate that variant ... Numbering begins with the first nucleotide ofthe first exon (up) andthe first amino-acid residue ofthe mature M protein (down) Dashes indicate nucleotides identical with those ofthe M allele The...
... partners ofthe mutated residues are shown in yellow andthe dipyrromethane (DPM) cofactor is shown inthe ball and stick representation Magenta indicates the beginning andthe end ofthe region ... blue and green, respectively; the positions ofthe mutated amino acids are indicated in red; andthe position ofthe last amino acid before the frameshift is shown in black The interacting partners ... deletion inthe present study causes a frameshift resulting inthe incorporation of 28 completely different residues and premature termination The mutated protein consists of 253 amino acids (361 in...
... shortage of funds, many underlying factors commonly foundin agricultural villages in central and western China, such as the poor allocation of funds andthe workings of informal institutions inthe ... the conclusion of her dissertation that increasing public investment is not enough and that establishing institutions for the allocation of public money, supervision of money spending, and others ... formal and informal institutions are combined to investigate the factors resulting inthe huge differences on the provision of different public goodsin agricultural villages in inland China This...
... for the dynamic nature ofthe Internet andthe information that can be found on it; The search for information is often limited to a few Internet services, such as the WWW Finding information ... alone Preamble • The information and information services on the Internet are very heterogeneous: information on the Internet is being offered in many different kinds of formats andin many different ... size ofthe Internet, let alone to make an estimation ofthe amount of information that is available on or through it; • The dynamic nature ofthe information on Internet: information that cannot...
... words is that the translations ofthe same words are not consistent from the beginning The other inappropriateness, to the best of my understanding, is the translation of nominal group There are ... it is Latin However, there still remains some minor inappropriateness such as the inconsistency in translating the same words, the misuse of some lexical items andthe translation of nominal group ... people, the consistency ofthe translation from the beginning ofthe book to the end ofthe book is crucial This helps avoid the misunderstanding that two translated versions ofthe same thing could...
... predicting proper strain rate involved three phases First, data collection phase involved gathering the data for use in training and testing the neural network A large training data reduces the ... risk of under-sampling the nonlinear function, but increases the training time To improve training, preprocessing ofthe data to values between and was carried out before presenting the patterns ... properties ofthe soil and results of consolidation test, to learn the database, and to predict the properties of consolidation SELECTION OF STRAIN RATE r= V − Vmin Vmax − Vmin Data Collection Data...
... using the equation of continuity, which represents a mathematical formula for the law of conservation of mass using the horizontal wind data (u, v) and calculate the divergence using finite differences ... prevailing weather at that time andthe nature ofthe region (as will be clarified later) Therefore, the values ofthe vertical velocity in summer is higher than winter It was noticed also from the ... obvious at night which lead to a stable weather, while at January, the vertical motion was ranging between upward and downward and this is due to the prevailing weather at that time andthe nature of...
... assessment ofthe importance of oral presentation skills in their future work, (2) the problems they might encounter when giving presentations, and (3) factors causing their difficulties and their ... completed by the students was the main instrument employed for the collection of data The research reveals that the students’ low language proficiency including unclear pronunciation, their bad ... 2.3 Data analysis and Discussion ofthe Findings 23 2.3.1 Data Analysis 23 2.3.2 Discussion ofthe Findings 24 2.3.2.1 The students’ assessment ofthe importance of...
... for the dynamic nature ofthe Internet andthe information that can be found on it; The search for information is often limited to a few Internet services, such as the WWW Finding information ... alone Preamble • The information and information services on the Internet are very heterogeneous: information on the Internet is being offered in many different kinds of formats andin many different ... size ofthe Internet, let alone to make an estimation ofthe amount of information that is available on or through it; • The dynamic nature ofthe information on Internet: information that cannot...
... assessing learners inthe process of forming the competencies and skills with the goal of helping them to continue that growth process On the other hand, formal testing occurs atthe end ofthe ... engages the audience by motivating them to listen by relating the topic to their interests The body must explain, support, and defend the theme inthe introduction All main points must be covered The ... developing the main body ofthe presentation; reinforcing the ideas outlined inthe main body and presenting the conclusion In second language classrooms, oral presentations are usually inthe form...
... with nine chemotherapy and/ or radiation therapy, ten controls) Further study using larger numbers of patients is needed to establish the accuracy of ADC measurement in monitoring the effect of therapy ... Detecting the keratinoid substance by means of DWI andthe ADC value may be useful and serve as an adjunctive tool to ensure the accuracy ofthe diagnosis, particularly in patients with fatless mature ... nodal status in this patient group Since the highly cellular tissue in reactive lymph nodes may also show increased intensity, the role of DWI and ADC in distinguishing between benign and malignant...
... considerable interest in understanding the role of all MTs inthe brain, and particularly within the injured or diseased brain Inthe case of GIF, the protein has many neuroprotective properties that could ... possible, then, that the upregulation and secretion of GIF by astrocytes inthe immediate vicinity of a lesion could contribute to the accumulation of reactive astrocytes atthe injury site Interestingly, ... evidence gathered to date regarding GIF synthesis in response to traumatic brain injury indicates that GIF may be involved inthe neuroinhibitory processes that are associated with glial scar formation...
... One ofthe most intriguing features ofthe sku mutant is that the mature larva accumulates branched-chain amino acids, leucine, isoleucine and valine, in haemolymph at levels times higher in ... template [7] The model of wild-type BmIVD indicated that all the side chains inthe loop connecting helices I and J are exposed on the surface ofthe monomer, pointing toward FAD or its neighbouring ... revealed the presence of a single point mutation in 1337 nucleotides of BmIVD Inthe sku mutant, the 1127th guanine from the start codon was substituted by thymine and none ofthe other sites...
... localization of intact CYP2E1 in yeast cells Because ofthe existing ambiguity inthe literature on the nature and extent of CYP2E1 import into mitochondria, we first established the relative purity ... signal, as inthe case of CYP1A1 [4]; and (b) PKA- or protein kinase C-mediated phosphorylation of nascent chains either atthe N-terminus (Ser128 or Ser129) or the C-terminus, which promotes the mitochondrial ... NADPH, and incubation was continued for 30 at 37 °C in a shaking water bath The reactions were terminated by adding mL of ice-cold methanol, and insoluble particles were sedimented by centrifugation...
... chemokines stimulated mainly by in ammatory cytokines, including IL-1b, TNF-a and IFN-c (B) Chemokines expressed inthe joint recruit leukocytes into the joints In addition to functioning in cell ... regulated mainly by TNF-a The role of chemokines in RA pathogenesis The chemokines listed above are implicated in RA pathogenesis via the recruitment and retention of leukocytes inthe joints In ... increased concentrations of several chemokines Chemokines inthe joints of patients Table Chemokines and chemokine receptors expressed inthe joint of RA patients Systemic name CC chemokines CCL2 CCL3...
... determine the roles of these DHSs on the transcription of Ig-b gene and on the maintenance ofthe active chromatin state Results Generation of DT40/Cre cells with a long deletion in one allele ofthe ... enhancing activity, as determined by transient transfection, was associated with DHSs inthe Na channel gene andinthe first intron ofthe Ig-b gene Furthermore, the acetylation status of H3 and ... (given in kb) was determined by kHindIII Size ofthe bands observed in each autoradiogram is indicated atthe right side The 6.6 kb band detected in lanes b, c, and d in autoradiogram (B), and lanes...
... of most individuals, the nature of these ideal refinements varies widely inthe studied dataset, and there is no single intuitive strategy leading to robust results Even if the attributes ofthe ... pages belong to the same domain or that they are near duplicates In those cases tokens and ngram QR will probably include non informative strings In some cases the QRs found are neither directly ... strategy The best type is affiliation, which is selected in 29% ofthe cases Affiliation and occupation together cover around half ofthe cases (54%), andthe rest is a long tail where each attribute...
... solvent-accessibility ofthe His210 side-chain Inthe protein interior, the dielectrostatic constant is lower than on the protein surface, while the dielectrostatic constant in water is about 80 and that inthe ... at residue 169 andthe pK2 showed a clear linear relationship (Fig 3B) The pK2 increased as the size ofthe residue at position 169 increased The effect ofthe size ofthe residue at position 169 ... a single peak at 37 °C (Fig 4) The data indicate that the split signals were originated by the one proton, His57 Nd1-Asp113 Oc2, i.e at high temperature, the interchange rate ofthe proton between...