ldl low density lipoprotein
Tài liệu Báo cáo khoa học: Affinity and kinetics of proprotein convertase subtilisin ⁄ kexin type 9 binding to low-density lipoprotein receptors on HepG2 cells docx
... the low density lipoprotein (LDL) receptor pathway A lattice model for LDL binding J Biol Chem 266, 19296– 19302 Hwang J & Menon KM (1983) Characterization of low density and high density lipoprotein ... Cummings RT, Calzetta A, Cubbon RM, Fischer PA et al (2007) Effects of pH and low density lipoprotein (LDL) on PCSK9-dependent LDL receptor regulation J Biol Chem 282, 20502–20512 20 Strom TB, Holla ... [125I]TC-PCSK9 (see below) TLDLR possesses distinct binding domains for apoB-100 (the main apolipoprotein in LDL) and PCSK9 In agreement with previous studies showing that LDL can inhibit the uptake...
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Tài liệu Báo cáo khoa học: Glycation of low-density lipoprotein results in the time-dependent accumulation of cholesteryl esters and apolipoprotein B-100 protein in primary human monocyte-derived macrophages docx
... different values compared to the native LDL (P > 0.05) Total cholesterol Native LDL LDL plus EDTA Methylglyoxal -LDL Glycolaldehyde -LDL Glucose -LDL Glucose -LDL + Cu2+ Free cholesterol Cholesteryl ... present in the artery wall [3] Lowdensity lipoproteins (LDLs) are the likely source of this lipid, with unregulated LDL uptake occurring via receptors other than the native LDL receptor, including CD36 ... using LDL- free medium following exposure of HMDMs to labeled glycolaldehyde- and methylglyoxal-modified LDL, and control LDL, for 96 h The use of LDL- free medium during the chase period allows...
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Báo cáo khoa học: Protective effect of dietary curcumin and capsaicin on induced oxidation of low-density lipoprotein, iron-induced hepatotoxicity and carrageenan-induced inflammation in experimental rats ppt
... Inhibition of oxidation of human low- density lipoprotein by phenolic substances in red wine Lancet 341, 544–547 Miyagi Y, Miwa K & Inoue H (1997) Inhibition of lowdensity lipoprotein oxidation by flavonoids ... 57 of low- density lipoprotein Am J Clin Nutr 53, 314S– 321S Jialal I & Grundy SM (1992) Effect of dietary supplementation with alpha-tocopherol on the oxidative modification of low- density lipoprotein ... and Industrial Research, New Delhi for the award of research fellowship References Goldstein JL & Brown MS (1977) The low- density lipoprotein pathway and its relation to atherosclerosis Annu Rev...
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Báo cáo khoa học: Protective effects of endomorphins, endogenous opioid peptides in the brain, on human low density lipoprotein oxidation pdf
... lipid peroxidation and antioxidants in oxidative modification of LDL Free Radic Biol Med 13, 341–390 Steinberg D (1997) Low density lipoprotein oxidation and its pathological significance J Biol ... acid-induced protein damage FEBS Lett 532, 80–84 49 Noguchi N & Niki E (1994) Apolipoprotein B protein oxidation in low- density lipoproteins Methods Enzymol 233, 490–494 FEBS Journal 273 (2006) 1275–1284 ... indirectly from copper on the surface of LDL particles and behave well as chain breaking antioxidant against Cu2+-induced LDL peroxidation Furthermore, Cu2+-induced LDL peroxidation is considered to...
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Báo cáo khoa học: Anti- and pro-oxidant effects of quercetin in copper-induced low density lipoprotein oxidation Quercetin as an effective antioxidant against pro-oxidant effects of urate potx
... Flavonoids and urate in copper-induced low- density lipoprotein oxidation (Eur J Biochem 271) 1999 pro-oxidant effects of urate in copper-induced low- density lipoprotein oxidation Eur J Biochem 269, ... low- density lipoprotein Free Rad Res 30, 1–9 Berliner, J.A., Territo, M.C., Sevanian, A., Ramin, S., Kim, J.A., Bamshad, B., Esterson, M & Fogelman, A.M (1990) Minimally modified low density lipoproteins ... by isolated human low density lipoprotein undergoing oxidation Free Radic Biol Med 25, 519–528 Lynch, S.M & Frei, B (1995) Reduction of copper not iron, by human low density lipoprotein J Biol...
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Báo cáo Y học: Structural and compositional changes in very low density lipoprotein triacylglycerols during basal lipolysis potx
... lipoprotein particles displacing especially apolipoprotein A-I [28] Apolipoprotein B or lipids were not displaced from low density lipoprotein (LDL) particles indicating that neither should there ... of rat hepatic very low density lipoproteins in the endoplasmic reticulum J Biol Chem 268, 3555–3562 Goldberg, I.J (1996) Lipoprotein lipase and lipolysis: central roles in lipoprotein metabolism ... U.J.F., Tsukamoto, K., Glick, J.M & Rader, D.J (2000) Hepatic apolipoprotein E expression promotes very low density lipoprotein- apolipoprotein B production in vivo in mice J Lipid Res 41, 1673–1679...
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Báo cáo khoa học: Binding areas of urokinase-type plasminogen activator– plasminogen activator inhibitor-1 complex for endocytosis receptors of the low-density lipoprotein receptor family, determined by site-directed mutagenesis doc
... to the endocytosis receptors alpha2-macroglobulin receptor low- density lipoprotein receptor-related protein and very -low- density lipoprotein receptor involves basic residues in the inhibitor ... Specicity of serine proteinase serpin complex binding to very -low- density lipoprotein receptor and alpha2macroglobulin receptor low- density- lipoprotein- receptor-related protein Eur J Biochem 248, ... 10 Li Y, Knisely JM, Lu W, McCormick LM, Wang J, Henkin J, Schwartz AL & Bu G (2002) Low density lipoprotein (LDL) receptor-related protein 1B impairs urokinase receptor regeneration on the cell...
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Báo cáo khoa học: Glycation and glycoxidation of low-density lipoproteins by glucose and low-molecular mass aldehydes Formation of modified and oxidized particles pot
... of LDL )1 LDL (density 1.019–1.063 gÆmL ) was prepared from plasma of fasted, healthy volunteers by density gradient ultracentrifugation as described previously [21] After isolation, LDL was dialysed ... bars, mg LDL proteinÆmL)1 with 100 mM GA; horizontal striped bars, mg LDL proteinÆmL)1 with 10 mM GA; dark stippled bars, mg LDL proteinÆmL)1 with mM GA; light stippled bars, 0.4 mg LDL proteinÆmL)1 ... modification of LDL? Atherosclerosis 99, 107–120 22 Esterbauer, H., Striegl, G., Puhl, H & Rotheneder, M (1989) Continuous monitoring of in vitro oxidation of human low density lipoprotein Free...
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Báo cáo Y học: Anti- and pro-oxidant effects of urate in copper-induced low-density lipoprotein oxidation pdf
... trigger for low density lipoprotein oxidation Biochim Biophys Acta 1347, 191198 39 Rice-Evans, C., Leake, D., Bruckdorfer, R & Diplock, A.T (1996) Practical approaches to low density lipoprotein ... by isolated human low density lipoprotein undergoing oxidation Free Radic Biol Med 25, 519528 47 Lynch, S.M & Frei, B (1995) Reduction of copper not iron, by human low density lipoprotein J Biol ... of low- density lipoprotein Free Radic Res 30, 19 35 Berliner, J.A., Territo, M.C., Sevanian, A., Ramin, S., Kim, J.A., Bamshad, B., Esterson, M & Fogelman, A.M (1990) Minimally modied low density...
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Báo cáo y học: "Autoantibodies to low-density-lipoprotein-receptor-related protein 2 (LRP2) in systemic autoimmune diseases" pps
... CD69-homologous amino acid sequence and one of the LDLR domains, which were thought to bind various ligands such as apolipoprotein Eβ very -low- density lipoproteins, lactoferrin, and aprotinin [17] ... with low density lipoprotein receptor-related protein in systemic autoimmune diseases J Immunol 2001, 166:1360-1369 Hussain MM: Structural, biochemical and signaling properties of the low- density ... expressed as a maltose-binding protein (MBP) fusion protein EGF, epidermal growth factor; LDL, low- density lipoprotein without anti-LRP2 autoAbs P values of less than 0.05 were considered to be...
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Báo cáo y học: " Patients with early rheumatoid arthritis exhibit elevated autoantibody titers against mildly oxidized low-density lipoprotein and exhibit decreased activity of the lipoprotein-associated phospholipase A2" pot
... high -density lipoprotein- cholesterol and autoantibody titers against oxidized low- density lipoprotein Correlation lipoprotein- cholesterol and autoantibody titers against oxidized low- density lipoprotein ... levels of high -density lipoprotein (HDL)-cholesterol and autoantibody titers against (a) oxidized low- density lipoprotein in the propagation phase (oxLDLP) and (b) oxidized low- density lipoprotein ... Oxidative modification of low- density lipoprotein (LDL) is an important event in the development and progression of atherosclerosis Oxidized low- density lipoprotein (oxLDL) is present in atherosclerotic...
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Báo cáo y học: "Inhibition of lectin-like oxidized low-density lipoprotein receptor-1 reduces leukocyte adhesion within the intestinal microcirculation in experimental endotoxemia in rats" potx
... oxidized low- density lipoprotein receptor-1 Proc Natl Acad Sci USA 2000, 97:360-364 Oka K, Sawamura T, Kikuta K, Itokawa S, Kume N, Kita T, Masaki T: Lectinlike oxidized low- density lipoprotein ... functional capillary density; FITC: fluorescein isothiocyanate; HR: heart rate; IgG: immunoglobulin G; IL: interleukin; IVM: intravital fluorescence microscopy; LDL: low- density lipoprotein; LOX-1: ... LOX-1 The exposure of LDL to oxidative stress generates OxLDL The expression of the OxLDL receptor LOX-1 is upregulated by the increased occurrence of OxLDL Interestingly, the OxLDL-induced upregulation...
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Functional role of low density lipoprotein receptor related protein 5 and 6 in alzheimers disease
... immunoprecipitation LCM control L-cell conditioned medium LDL low density lipoprotein LOAD late-onset Alzheimer's disease LRP low density lipoprotein receptor-related protein L-Wnt-3a cells L-cells ... dynamics in AD 13 1.4 ApoE receptors 14 1.4.1 Low density lipoprotein receptor family 14 1.4.2 Low density lipoprotein- related protein and 16 1.4.3 Dysregulated Wnt ... through its receptors 14 ApoE receptors include the core members from LDL receptor family such as low density lipoprotein (LDL) receptor-related protein (LRP) 1, apoE receptor (apoER2) as well...
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Cellular gene expression profiles of human macrophages exposed to chlamydia pneumoniae and treated with low density lipoprotein
... sphere The major types of lipoproteins includes chylomicrons, very low density lipoproteins (VLDL), low density lipoproteins (LDL) , lipoprotein Lp(a) and high density lipoproteins (HDL) Chylomicrons ... Chlamydia pneumoniae, and low density lipoprotein Introduction The second model consists of human macrophage U937 cell line and low density lipoprotein, after addition of low density lipoprotein The model ... oxidation (Kuo C.C., et al 1993.) Following an elevation in plasma low density lipoprotein (LDL) cholesterol levels will result in the penetration of low density lipoprotein into the arterial wall...
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Xác định cơ sở phân tử của bệnh cao cholesterol trong máu có tính chất gia đình liên quan đến gen LDLR (low density lipoprotein receptor)
... sapiens low density lipoprotein receptor (LDLR) gene Homo sapiens low density lipoprotein receptor (LDLR) Homo sapiens low density lipoprotein receptor (LDLR) gene Homo sapiens low density lipoprotein ... receptor (LDLR) gene Homo sapiens low density lipoprotein receptor (LDLR) gene Homo sapiens low density lipoprotein receptor (LDLR) gene Homo sapiens low density lipoprotein receptor (LDLR) gene ... High Density Lipoprotein heFH heterozygous Familial Hypercholesterolemia hoFH homozygous Familial Hypercholesterolemia LDL Low Density Lipoprotein LDLR Low Density Lipoprotein Receptor LDLRAP1 LDLR...
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Tài liệu Báo cáo khoa học: ¨ Induction of Kruppel-like factor 4 by high-density lipoproteins promotes the expression of scavenger receptor class B type I pptx
... atherogenesis Materials and methods HDL isolation and LDL oxidization HDL2 (density = 1.063–1.125 gÆmL)1), HDL3 (density = 1.125–1.210 gÆmL)1) and LDL (density = 1.019–1.063 gÆmL)1) were isolated from ... 200 100 * * Neo B KLF4 Neo Norm Normal oxLDL HDL3 * KLF4 oxLDL HDL3 Norm oxLDL HDL3 SR-BI Ratio of hSR-BI protein /GAPDH GAPDH * 0.8 * * 0.6 * 0.4 Normal oxLDL HDL3 * 0.2 C Neo Ctrl Mock KLF4 siRNA ... hSR-BI mRNA /GAPDH C D * * 0.8 Ctrl oxLDL HDL2 HDL3 0.6 0.4 0.2 PBMC THP-1 * * 500 400 300 200 * PBMC PMBC Ctrl Ctrl oxLDL HDL3 * 100 THP-1 THP-1 oxLDL HDL3 Ctrl oxLDL HDL3 SR-BI Ratio of hSR-BI protein...
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Tài liệu Báo cáo khoa học: Trophoblast-like human choriocarcinoma cells serve as a suitable in vitro model for selective cholesteryl ester uptake from high density lipoproteins pdf
... internalization of low density lipoprotein by human placental cells Histochemistry 87, 457–464 Cummings, S.W., Hatley, W., Simpson, E.R & Ohashi, M (1982) The binding of high and low density lipoproteins ... 270) deletion of low- density lipoprotein receptor function J Cell Physiol 180, 190–202 59 Vassiliou, G., Benoist, F., Lau, P., Kavaslar, G.N & McPherson, R (2001) The low density lipoprotein receptor-related ... receptor SR-BI as a high density lipoprotein receptor Science 271, 518–520 37 Goldstein, J.L., Basu, S.K & Brown, M.S (1983) Receptormediated endocytosis of low- density lipoprotein in cultured...
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Báo cáo khoa học: Plasmodium falciparum merozoite surface protein 1 Glycosylation and localization to low-density, detergent-resistant membranes in the parasitized erythrocyte pdf
... the environment of ordered lipids [29] and accumulate in the low density, detergent-resistant membranes recovered after equilibrium density centrifugation of Triton X-100 lysates of mammalian ... vesicles with the target cell membrane [39] The low Mr C-terminal MSP-1 fragments, like the endogenous GPI-linked CD59, are selectively enriched in low density, detergent-resistant membranes of the ... However, following SDS/ PAGE separation of MSP-1 fragments, the labelled GPI anchors appear dissociated from the 19-kDa fragment carrying the C-terminal epitope (compare Figs and 3) The lower Mr...
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Introducing Low-Density Parity-Check Codes doc
... Topic 1: Low- Density Parity-Check Codes 1.1 Introduction Low- density parity-check (LDPC) codes are forward error-correction codes, ... very well with a much reduced complexity Introducing Low- Density Parity-Check Codes, Sarah Johnson ACoRN Spring School version 1.1 1.3 Low- density parity-check (LDPC) codes As their name suggests, ... 3.7: The evolution of probability density functions with iteration number in density evolution See Example 3.5 z = f (x, y) the density of z can be found as follows: f (z)dz = f (x, y)dxdy ∆Dz...
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Báo cáo Y học: Biophysical characterization of the interaction of high-density lipoprotein (HDL) with endotoxins doc
... Northoff, H (1993) Prevention of endotoxin-induced monokine release by human low- and high -density lipoproteins and by apolipoprotein A-I Infect Immun 61, 5140–5146 Yu B., Hailman, E & Wright, S.D ... Distribution and kinetics of lipoproteinbound endotoxin Infect Immun 69, 2821–2828 Casas, A.T., Hubsch, A.P., Rogers, B.C & Doran, J.E (1995) Reconstituted high -density lipoprotein reduces LPS-stimulated ... mutant F515 from Escherichia coli by HF treatment at low temperature (4 °C) The detailed procedure is described elsewhere [7] High -density lipoprotein (HDL) from human plasma was purchased from...
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Tìm thêm: xác định các mục tiêu của chương trình khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25