iq and ptsd related symptoms in both groups of children
Báo cáo y học: " Psychopathological status, behavior problems, and family adjustment of Kuwaiti children whose fathers were involved in the first gulf war" ppsx
... children of men with PTSD (compared with the children of the retired and AIA and the men without PTSD) Similarly, children of mothers with PTSD/ anxiety/depression, larger number of offspring, with ... Education and Training, Kuwait, and the Ministry of Defense, Kuwait All responding veterans gave written informed consent for their wives and children to be interviewed Accordingly, the rest of the ... levels of symptoms of anxiety, depression, somatization, anger, and low self-esteem However, the findings were not linked to indices of behavior and family adjustment, and the surveys did not include...
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Tài liệu Báo cáo khoa học: Delineation of exoenzyme S residues that mediate the interaction with 14-3-3 and its biological activity ppt
... questions using a strategy of single amino acid site-directed mutagenesis Delineation of ExoS residues of the cofactor interaction domain within ExoS Various single mutant ExoS proteins were tested for ... phosphorylation-independent binding The interaction between 14-3-3 and ExoS is important for the ADP ribosylation activity of ExoS and even more intriguingly, appears to be independent of serinephosphorylation ... The basic cluster of amino acids in the binding groove of 14-3-3, including amino acids Lys-49, Arg56, Lys-120 and Arg-127, in an otherwise acidic molecule, are important for the interaction with...
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Tài liệu Báo cáo khoa học: Inhibitory effects of nontoxic protein volvatoxin A1 on pore-forming cardiotoxic protein volvatoxin A2 by interaction with amphipathic a-helix doc
... fragment in VVA2 was identified as the membrane-binding domain [6] These results suggest that the N-terminal and the C-terminal pair of a-helices of VVA1 can bind to VVA2 independently of each other and ... molecule of VVA2 has one binding site for interacting with either VVA1 or VVA2 Additional investigation of the characteristics of binding of VVA2 to VVA1 will be necessary to further understand this ... presence of VVA2 in the pellet fraction (Fig 1B, lanes and 6) Intriguingly, the presence of VVA1 inhibited the oligomerization of VVA2 and thus its binding to simple lipid membranes (Fig 1B, lanes and...
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Tài liệu Báo cáo khoa học: Major phosphorylation of SF1 on adjacent Ser-Pro motifs enhances interaction with U2AF65 doc
... U2AF65 binding N-terminal region of SF1 and its RNA binding domain, suggesting that phosphorylation of these sites might regulate the formation of the KIS + + + U2AF65 ∆RS 35S binding (% of input) ... a serine ⁄ threonine kinase domain and a C-terminal UHM domain Mutation of lysine 54 to arginine (KIS[54R]) impairs the kinase activity of KIS [26] KIS [1–313] entirely lacks the UHM domain, whereas ... lane 7) Interestingly, KIS bound SF1f as efficiently as U2AF65DRS, a U2AF65 construct lacking its N-terminal arginine and serine rich (RS) domain (Fig 2, lane 12) In our conditions, binding of U2AF65DRS...
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Tài liệu Báo cáo khoa học: Plant a-amylase inhibitors and their interaction with insect a-amylases ppt
... an intermediate during the hydrolytic pathway of glucosidases [42] The properties of nonproteinaceous inhibitors make them interesting in the ®eld of medicine, both for treatment [43] and in ... [104] and the ricin B chain [105] In the cases of a-AI1, AAI and RBI, inhibition involves the insertion of inhibitor loops into the a-amylase active site, thereby establishing a network of hydrogen ... [99,103] [128] [112,113] [88] [132] Subtilisin Inhibition Subtilisin Inhibition Subtilisin Inhibition Trypsin Inhibition Trypsin Inhibition Trypsin Inhibition Chitinase 406 O L Franco et al (Eur J Biochem...
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Tài liệu MECHANICAL PROPERTIES OF THE HEART AND ITS INTERACTION WITH THE VASCULAR SYSTEM ppt
... troponin and tropomyosin Tropomyosin is a thin protein strand that sits on the actin strand and, under normal resting conditions, covers the actin-myosin binding site thus inhibiting their interaction ... understanding and will be the focus and repeating theme throughout the text A sound understanding of cardiac physiology begins with basic understanding of cardiac anatomy and of the physiology of ... rises and calcium binds to troponin C, troponin I releases from actin allowing the tropomyosin molecule to be pulled away from the actin-myosin binding site This eliminates inhibition of actin-myosin...
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Báo cáo khoa học: Peptides from purified soybean b-conglycinin inhibit fatty acid synthase by interaction with the thioesterase catalytic domain pot
... (258–268) (165–178) subunit subunit subunit subunit subunit of of of of of b-conglycinin b-conglycinin b-conglycinin b-conglycinin b-conglycinin Accession no P13916 P25974 P13916 P25974 P13916 FEBS ... the ER domain higher than those in the TE domain (Table 3) Docking of the RKQEEDEDEEQQRE inhibitory peptide predicted near equivalent interaction energies in the ER and TE domains In both sites, ... large inhibitors and that the TE domain is a better target for these types of peptide inhibitors To confirm the binding of these peptide inhibitors in the TE domain, a biochemical enzyme inhibition...
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Báo cáo khoa học: Ion-binding properties of Calnuc, Ca2+ versus Mg2+ – Calnuc adopts additional and unusual Ca2+-binding sites upon interaction with G-protein pdf
... prominent J-band and c-band in both absorption and CD spectra (Fig 6A,B) Furthermore, Ca2+ ‘competes off’ the dye (attenuating both the J-band and the c-band), indicating that the dye binds in ... differentiate between kinds of Ca2+-binding proteins [25,47,48] Caday and Steiner reported a change in the absorption spectral pattern of Stains-all upon binding to Ca2+-binding proteins, and that it could ... occurring in Calnuc upon metal ion binding Ca2+ and Mg2+ binding lead to an increase in the fluorescence intensity of the tryptophans in an ion-dependent fashion Ca2+ binding leads to a two-fold increase...
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Báo cáo khoa học: SHIP2 interaction with the cytoskeletal protein Vinexin ppt
... in enhancing insulin sensitivity and regulating obesity in vivo [21,22] This may involve a change in protein kinase B (PKB) activity as shown in liver and muscle by the injection of insulin in ... 3-kinase (PI 3K) product PtdIns(3,4,5)P3 Both SHIP1 and SHIP2 contain a series of protein-interacting domains Both proteins possess a SH2 domain at their N-terminal end, a catalytic domain in ... localization of a complex between Vinexin and SHIP2 Therefore, the interaction of Vinexin and SHIP2 could be a link between the role of Vinexin in cytoskeleton organization and PtdIns(3,4,5)P3...
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Báo cáo khoa học: tmRNA from Thermus thermophilus Interaction with alanyl-tRNA synthetase and elongation factor Tu pptx
... ToolboxÕ add -in (MDL Information Systems, Inc) for Microsoft EXCEL Results The sequence of the ssrA gene of T thermophilus HB8 determined in this study differs in a single base (G310 instead of A310) ... EF-Tu and tmRNA assumes the presence of two interacting EF-Tu binding sites on Ala$tmRNA One of those corresponds to the tRNA-like module of tmRNA and was designated as the canonical EF-Tu binding ... charged with histidine Another specific EF-1a binding site is located within the upstream pseudoknot domain, and in that case EF-1a binding does not depend on aminoacylation of the viral RNA The...
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Báo cáo khoa học: Concerted mutation of Phe residues belonging to the b-dystroglycan ectodomain strongly inhibits the interaction with a-dystroglycan in vitro pot
... peptides spanning the C-terminal domain of a-DG and the b-DG ectodomain by solid-phase binding assays and SPR, demonstrating that despite the intrinsic pitfalls of solid-phase binding techniques, extensively ... [15] In order to identify the specific amino acids within the linear interacting epitopes involved in the complex between a-DG and b-DG, alanine scanning of some of the residues that were mainly in uenced ... nonlinear detection in ELISA resulting in up to 1000-fold too high affinities of fibrinogen binding to integrin alpha IIb beta FEBS Lett 358, 179–181 28 Ying M & Flatmark T (2006) Binding of the viral...
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Báo cáo khoa học: Intermonomer cross-linking of F-actin alters the dynamics of its interaction with H-meromyosin in the weak-binding state ppt
... estimated Concentration of the proteins: 80 lM (actin) and lM (HMM) Diagnostic ratio L¢¢ ⁄ L Control F-actin alone Strong-binding state Weak-binding state Actin Actin Actin Actin Actin + + + + HMM HMM ... strong binding of HMM and HMM ⁄ ADP complex to F-actin the L¢¢ ⁄ L ratios indicate near equal strong immobilization of the motion In the weak binding state of F-actin–HMM ⁄ AMPPNP and F-actin– HMM ... interaction of ATP and S1 with actin during activation of myosin S1 ATPase using caged ATP did not produce an increase in rotational motion in the environment of the Cys374 site of actin [8] In a recent...
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Báo cáo khoa học: Identification of amino acids in antiplasmin involved in its noncovalent ‘lysine-binding-site’-dependent interaction with plasmin pptx
... lysine-binding-site-mediated interaction between plasmin and antiplasmin Molecular modelling of the C-terminal portion of antiplasmin The amino-acid sequence of the C-terminal 40 residues in antiplasmin ... between plasmin and antiplasmin is of great importance in regulating the fibrinolytic process and keeping the plasmin active in the right place and at the correct time, as fibrin and antiplasmin compete ... addition, the side chain of Lys436 in our computer model is found at the surface of the molecule and may definitely be involved in interactions with a lysine-binding site in plasmin Some of the mutants,...
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Báo cáo khoa học: Amino acid residues on the surface of soybean 4-kDa peptide involved in the interaction with its binding protein potx
... hydrophobic triplet of PheB24, PheB25 and TyrB26 of the C-terminal B-chain domain of insulin is important for directing the affinity of insulin receptor interaction [18–22] As Leu27 and Phe28 of the 4-kDa ... consisting of Val23, Val29, Phe31 and Ile33 in the 4-kDa peptide [8] is involved in binding to the 43-kDa protein because of topochemical similarity to the active area of insulin consisting of ValA3, ... Nakagawa, S.H & Tager, H.S (1987) Role of the COOHterminal B-chain domain in insulin–receptor interactions: identification of perturbations involving the insulin mainchain J Biol Chem 262, 12054–12058...
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Báo cáo khoa học: Crystal structure of RNase A tandem enzymes and their interaction with the cytosolic ribonuclease inhibitor potx
... more relaxed in solution, thereby enabling RI binding to both the N-terminal and the C-terminal RNase A entities The distance between the C-terminus of the first and the N-terminus of the ˚ second ... C-terminally swapped) ds-RNase A dimers are suggested to bind two RI molecules in vitro, resulting in an inactive complex [19], BS-RNase evades RI binding [14,21] To elucidate the mode of binding of ... (3.6 and 1.7), because of the individual staining properties of RNase A, SGRSGRSGRATE, and RI, but clearly indicate a : binding stoichiometry in the RI–RATE complex Fig Analysis by SDS ⁄ PAGE of...
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Báo cáo khoa học: A L225A substitution in the human tumour suppressor HIC1 abolishes its interaction with the corepressor CtBP docx
... late in their life with a predominance of sarcomas and lymphomas in females and of carcinomas in males [2] It would thus be interesting to determine if heterozygous mice carrying the L225A point ... lanes 14 and 16) Thus, binding of a CtBP-interacting partner containing a PxDLS or a GxDLS motif is mediated by the same peptide recognition cleft in the CtBP N-terminal region Point mutation of the ... significant increase in the amount of CtBP1 coimmunoprecipitated was observed in the presence of CoCl2 (Fig 2D; compare lanes and 8), indicating that the interaction between HIC1 and CtBP1 is favoured in...
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Báo cáo khoa học: Contribution of a central proline in model amphipathic a-helical peptides to self-association, interaction with phospholipids, and antimicrobial mode of action ppt
... binding, and membrane-disrupting activity of antimicrobial peptides, we generated amphipathic a-helical peptides with different chain lengths (17, 21, and 25 residues) and containing or lacking ... Central proline in amphipathic a-helix S.-T Yang et al Quenching of the intrinsic fluorescence by acrylamide To compare the membrane-integrated state of PCPs and PFPs following their interaction ... PFPs and PCPs seem to be in line with those of Zelezetsky et al [46], using different types of aggregating ⁄ nonaggregating model peptides Discussion Fig Kinetics of membrane depolarization of...
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Báo cáo khóa học: Identification of domains on the extrinsic 23 kDa protein possibly involved in electrostatic interaction with the extrinsic 33 kDa protein in spinach photosystem II ppt
... GME in both the protein in solution and bound to PSII [34] This suggests that most of the carboxyl groups on the 33 kDa protein are not located in regions interacting with PSII intrinsic proteins ... cross-linkers (6–14 A span) indicated ˚ that the 33 kDa protein is within a distance of 11 A of the 23 kDa protein and that the 23 kDa protein is within ˚ 11 A of the 17 kDa protein [25] This indicates ... modified in a fraction of the protein by NSP but not in other fractions of the protein The 23 kDa protein modified with 0.5 mM NSP lost about 82% of its binding and reactivating capabilities (Figs and...
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Báo cáo khoa học: Aptamers toEscherichia colicore RNA polymerase that sense its interaction with rifampicin, r-subunit and GreB ppt
... the binding buffer was 440 mM in the case of aptamers and 200 mM in the case of MS Binding was measured as described in Materials and methods and normalized to the binding in the absence of Rif ... case of the aptamers and 200 mM salt in the case of MS (B) Inhibition of the binding of aptamer E9 (0.03 nM) to the core enzyme (3 nM) by increasing amounts of GreB Binding was measured in buffer ... (A) Inhibition of the binding of aptamer E2 and MS (0.1 nM) to the core polymerase (1 and nM, respectively) by increasing concentrations of the r-subunit Binding buffer contained 440 mM salt in...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ lồng sóc các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25