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intrinsic biological aging as underlying pathogenetic mechanisms in dementias of the alzheimer s type

Mobil 1 is original equipment in some of the world’s finest vehicles, including potx

Mobil 1 is original equipment in some of the world’s finest vehicles, including potx

Cao đẳng - Đại học

... excellent results in industry standard tests, most of which use completely rebuilt engines for each new test run Mobil 1 s outstanding results in these tests demonstrate that proper break -in using Mobil ... Mobil Success Stories 18 Success Stories China USA Poland Trust the Experts “I closed my eyes as I turned the ignition key and the engine fired up immediately It was incredible The engine had ... provides outstanding shear stability, resisting viscosity breakdown in high-performance engines and transmissions in bikes that use a common lubrication system for the engine and transmission •...
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Báo cáo khoa học: In vitro gamma-secretase cleavage of the Alzheimer’s amyloid precursor protein correlates to a subset of presenilin complexes and is inhibited by zinc potx

Báo cáo khoa học: In vitro gamma-secretase cleavage of the Alzheimer’s amyloid precursor protein correlates to a subset of presenilin complexes and is inhibited by zinc potx

Báo cáo khoa học

... overexpress the c-secretase complex components These assays are used to test the effects of detergent concentration, solvents and metals on the c-secretase cleavage of APP substrates These studies show ... of c-secretase activity Lastly, zinc causes structural changes in a c-secretase substrate and acts as an inhibitor of csecretase cleavage of APP Results Design of a novel APP c-secretase substrate ... slightly faster than the e-CTF (B) Sensitivity of exogenous substrate c-secretase assay in the presence of 0.5% CHAPSO Guinea pig brain soluble c-secretase was diluted to 0.5% CHAPSO and further...
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Báo cáo y học:

Báo cáo y học: "Parvovirus B19 Genotype Specific Amino Acid Substitution in NS1 Reduces the Protein’s Cytotoxicity in Culture"

Y học thưởng thức

... http://www.medsci.org Int J Med Sci 2010, Statistical Analysis Student t-test was used to assess the statistical significance in the data RESULTS Substitution I181M in B19 NS1 interferes with NS1-induced ... apoptosis as the underlying mechanism for the cytotoxicity observed in the setting of transient B19 NS1 expression (34) We therefore examined whether the reduced cell loss observed in the PathI substitution- ... hepatocytes as well as in HepG2 cells was shown to be cytotoxic (34) Activation of the innate apoptotic cascade was demonstrated to be the route of cell demise in the setting of B19 NS1 over-expression,...
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Application of house’s model for translation quality assessment in assessing the english version of the vietnam’s law on investment no. 59/2005/qh11

Application of house’s model for translation quality assessment in assessing the english version of the vietnam’s law on investment no. 59/2005/qh11

Thạc sĩ - Cao học

... quality assessment In this chapter, House s model for translation quality assessment will first be presented and then applied in assessing the English translation of the Law on Investment 2005 of ... activities for business purposes; the rights and obligations of investors; the guarantee of lawful rights and interests of investors; encouragement of investment and investment incentives; State administration ... concepts of translation theory in general, legal translation in particular Then it will test the appropriateness of House s model for translation quality assessment in assessing English translations...
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HIV infections rise in women of the Mekong

HIV infections rise in women of the Mekong

Sức khỏe phụ nữ

... phòng lây nhiễm HIV từ mẹ sang vào hệ thống chăm s c s c khỏe sinh s n s c khỏe bà mẹ trẻ em thức Điều mang lại hiểu cao việc cung cấp dịch vụ chăm s c s c khỏe sinh s n s c khỏe bà mẹ - trẻ em ... Newspaper : VN Express Date : December 1, 2012 Page/Link : http://vnexpress.net/gl/suc-khoe/2012/12/nhung-nan-nhan-vo-toi-cua-hiv/ The innocent victims of HIV Những nạn nhân ... đời Tôi s đưa bé S i Gòn khám biết mắc bệnh”, bà S u kể Theo tư vấn bác s , Trâm điều trị ngoại trú cách mang thuốc nhà uống tái khám theo lịch Việc chữa trị kéo dài chưa đến năm cô học sinh lớp...
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The images of women in some of william shakespeare,s plays

The images of women in some of william shakespeare,s plays

Khoa học xã hội

... According to Portias plan, she dresses as a doctor of law and Nerissa dresses as her clerk, they come to the court as deputy of Portias cousin, Bellario In this court, Shylock refuses to forgo his ... Antonios ships have sunk, so now he is bankrupt, and Shylock is insisting on a pound of his flesh as his merry bond written She knows that this news is the cause of Bassanios worry about his friend ... the absence of the sun (Act V, scene 1) One more interesting story in the play is that of the rings Portia and Nerissa pretend to ask their husbands about their rings and why they lost them They...
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Tài liệu Nutrition in the First 1,000 Days - State of the World’s Mothers 2012 ppt

Tài liệu Nutrition in the First 1,000 Days - State of the World’s Mothers 2012 ppt

Sức khỏe trẻ em

... even in resource-constrained settings Stunting rates have gotten worse in 14 countries, most of them in subSaharan Africa Somalia has shown the worst regression – stunting rates in that country increased ... feeding indicators has contributed to Madagascar s success in saving hundreds of thousands of lives.87 Madagascar s Ministry of Health, in partnership with the AED/Linkages Project (funded by USAID), ... developing countries are put to the breast within one hour of birth Establishing good breastfeeding practices in the first days is critical to the health of the infant and to breastfeeding success Initiating...
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Tài liệu Deteriorating Access to Women’s Health Services in Texas: Potential Effects of the Women’s Health Program Affiliate Rule doc

Tài liệu Deteriorating Access to Women’s Health Services in Texas: Potential Effects of the Women’s Health Program Affiliate Rule doc

Sức khỏe phụ nữ

... access for the poorest patients Operational restructuring, such as by closing some sites and reducing staff, in light of the loss of operating funds Reexamination of their services, perhaps reducing ... nationally.27 These shortages are particularly severe in areas outside of the major metropolitan areas of Texas, such as Houston, Dallas, or San Antonio About half of the 254 counties in Texas are considered ... rise several-fold Paradoxically, as the number of WHP patients who can continue to be served climbs, the state s budget losses grow larger These are estimates based on some basic assumptions; the...
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Tài liệu Investigation of Organic Chemicals Potentially Responsible for Mortality and Intersex in Fish of the North Fork of the Shenandoah River, Virginia, during Spring of 2007 ppt

Tài liệu Investigation of Organic Chemicals Potentially Responsible for Mortality and Intersex in Fish of the North Fork of the Shenandoah River, Virginia, during Spring of 2007 ppt

Tự động hóa

... and assess the estrogenicity of the complex mixtures of chemicals present using an in vitro assay Passive sampling technology was chosen to characterize AOCs in the watershed because of the expected ... and the result was given as mass of chemical in the passive 6   Investigation of Organic Chemicals in the North Fork of the Shenandoah River, Virginia, Spring 2007 sampler Although the mass of ... PCB measurements One of the SPMDs not containing PRCs in each canister was screened for estrogenic chemicals by the YES assay and the remaining SPMD was held in reserve Agricultural Pesticides Details...
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Tài liệu In Search of the Unknown docx

Tài liệu In Search of the Unknown docx

Cao đẳng - Đại học

... excavated ruts However, it was plain that the trustees of the society expected the resignation of Professor Farrago, for they had been in secret session all day, considering the names of possible candidates ... answers to correspondents who wrote offering their services as hunters of big game, collectors of all sorts of fauna, trappers, snarers, and also to those who offered specimens for sale, usually ... drowsy note of the male bird, the fainter responses of the female, the thin plaints of the chicks, huddling under her breast; I heard 17 their flipper-like, embryotic wings beating sleepily as the...
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Tài liệu THE STATE OF THE WORLD’S CHILDREN 2012: Children in an Urban World pptx

Tài liệu THE STATE OF THE WORLD’S CHILDREN 2012: Children in an Urban World pptx

Sức khỏe trẻ em

... because of the stresses of their living conditions As the prevalence of physical and social settings of extreme deprivation increases, so does the risk of reversing the overall success of disease ... disaster pushes large numbers of people into these areas The results of such a surge in users can include the contamination of drinking water Sanitary toilet systems consisting of commodes that ... access to alcohol and illegal drugs than their counterparts in rural areas They may resort to these substances as a means of coping with stress or as an outlet for idleness and frustration in the...
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Tài liệu Live Red in support of the Heart and Stroke Foundation of Manitoba pdf

Tài liệu Live Red in support of the Heart and Stroke Foundation of Manitoba pdf

Tổ chức sự kiện

... difference in the lives of thousands of Manitobans affected by heart disease and stroke Assist us in raising awareness and funds by hosting your own Live Red fundraiser in support of the Heart and Stroke ... as well as within the business community • ncreased brand loyalty and I sales By promoting a cause close to your customers’ hearts, you spark customer s interests and retain business •  ifferentiates ... budget Since 80% of Canadians have at least one risk factor for heart disease or stroke, Live Red closely supports the needs and interests of key stakeholders, including customers, employees and their...
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Tài liệu The Color Line A Brief in Behalf of the Unborn pptx

Tài liệu The Color Line A Brief in Behalf of the Unborn pptx

Khoa học xã hội

... difference in stature, the negroes being at least as tall as the Europeans." "In interpreting these facts, we must ask, Does the increase in the size of the brain prove an increase in faculty? This would ... feel themselves the victims of gross injustice And herein lies the profound and disastrous significance of the Washington incident and its fellows They are open proclamations from the housetops of ... attempts to transcend them are idle In music, in plastic art, in literature, in all higher forms of mental activity, even in the professions and in business, the same state of case is present The...
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Tài liệu Báo cáo khoa học: A novel c-N-methylaminobutyrate demethylating oxidase involved in catabolism of the tobacco alkaloid nicotine by Arthrobacter nicotinovorans pAO1 ppt

Tài liệu Báo cáo khoa học: A novel c-N-methylaminobutyrate demethylating oxidase involved in catabolism of the tobacco alkaloid nicotine by Arthrobacter nicotinovorans pAO1 ppt

Báo cáo khoa học

... according to the suggestions of the supplier (Amersham Biosciences) Determination of enzyme activity Enzyme activity was determined by using the peroxidasecoupled assay, consisting of 20 mM potassium ... lysate at 13 000 g was used to isolate the proteins on Ni-chelating Sepharose, as described by the supplier of the Sepharose (Amersham Biosciences, Freiburg, Germany) The isolated protein was ... [36] During the course of this work, the structure of dimethylglycine oxidase from A globiformis was published [38] Examination of the structure shows that the serine side-chain, corresponding to...
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Tài liệu Báo cáo khoa học: The molecular surface of proteolytic enzymes has an important role in stability of the enzymatic activity in extraordinary environments pptx

Tài liệu Báo cáo khoa học: The molecular surface of proteolytic enzymes has an important role in stability of the enzymatic activity in extraordinary environments pptx

Báo cáo khoa học

... KAVSSGIVVAAAAGNEGSSGSSSTVGYPAKYPSTIAVGAVNSSNQRASFSSAGSELDVMAPGVSIQSTLP KAVSSGIVVAAAAGNEGSSGSSSTVGYPAKYPSTIAVGAVNSSVQRASFSSAGSELDVMAPGVSIQSTLP KAVASGVVVVAAAGNEGTSGSSSTVGYPGKYPSVIAVGAVDSSNQRASFSSVGPELDVMAPGVSIQSTLP ... KAYASGIVVVAAAGNSGSSGSQNTIGYPAKYDSVIAVGAVDSNKNRASFSSVGAELEVMAPGVSVYSTYP KAVSSGIVVAAAAGNEGSSGSTSTVGYPAKYPSTIAVGAVNSSNQRASFSSVGSELDVMAPGVSIQSTLP KAVSSGIVVAAAAGNEGSSGSTSTVGYPAKYPSTIAVGAVNSSNQRASFSSAGSELDVMAPGVSIQSTLP KAVSSGIVVAAAAGNEGSSGSSSTVGYPAKYPSTIAVGAVNSSNQRASFSSAGSELDVMAPGVSIQSTLP ... TIAALNNSIGVLGVSPSASLYAVKVLDSTGSGQYSWIINGIEWAISNNMDVINMSLGGPTGSTALKTVVD TIAALNNSIGVLGVSPSASLYAVKVLDSTGSGQYSWIINGIEWAISNNMDVINMSLGGPSGSTALKTVVD TIAALNNSIGVLGVSPSASLYAVKVLDSTGSGQYSWIINGIEWAISNNMDVINMSLGGPSGSTALKTVVD...
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Memory performance in healthy elderly without Alzheimer’s disease: effects of time and apolipoprotein-E pptx

Memory performance in healthy elderly without Alzheimer’s disease: effects of time and apolipoprotein-E pptx

Sức khỏe người cao tuổi

... individuals with and without an APOE-␧4 allele Please note The intervals on the X axis represent the average time of follow-up assessments after baseline These are smoothed regression lines that ... elderly individuals without AD or QD, but other cognitive skills remained stable Increased age was associated with lower scores in all cognitive domains while increased education was associated ... Whether APOE-␧4 has a direct effect on memory in the absence of disease, or acts only through its association with AD, remains unknown because the majority of studies have been either cross-sectional...
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As Required by Section 939(h) of the Dodd-Frank Wall Street Reform and Consumer Protection Act ppt

As Required by Section 939(h) of the Dodd-Frank Wall Street Reform and Consumer Protection Act ppt

Ngân hàng - Tín dụng

... publish a variety of other types of credit ratings and assessments using various scales and measures Each of the three largest NRSROs has dozens of rating scales For example, Fitch, among other ... http://www.standardandpoors.com/ratings/form-nrsro/en/us 15 As discussed above, the Commission stated in 2005 that similarities in the scales and symbols used by NRSROs “suggests the existence of a market-based standard.” 52 The following ... Issuers of asset-backed securities • Issuers of government securities • Financial institutions • Insurance companies • Corporate issuers Egan-Jones Ratings Co (“EJR”) 12/21/2007 • Issuers of asset-backed...
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