improvement and applications of single domain antibodies

Báo cáo khoa học: Llama single-domain antibodies directed against nonconventional epitopes of tumor-associated carcinoembryonic antigen absent from nonspeciﬁc cross-reacting antigen doc

... isolation of singledomain antibodies (sdAbs) consisting of the variable domain of these heavy chain antibodies, also named VHH [2] These minimal antibody domains are endowed with a large number of properties ... conventional antibodies and are a good source of enzyme inhibitors [5] Most importantly, the single- domain nature of VHH permits the ampliﬁcation and subsequent straightforward cloning of the corresponding ... with three tandemly repeated loop-domains in CEA Comparisons between the extracellular domains of CEA and NCA show that the N-terminal and adjacent loop-domains of each apoprotein have high sequence...

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Báo cáo y học: "Translational Medicine and Reliability of Single-Nucleotide Polymorphism Studies: Can We Believe in SNP Reports or Not"

Danh mục: Y học thưởng thức

... Skovlund E, Nesland JM, Borresen-Dale AL Single tube multiplex polymerase chain reaction genotype analysis of GSTM1, GSTT1 and GSTP1: relation of genotypes to TP53 tumor status and clinicopathological ... interpretation of potential misleading sources of literature-bias The existence of such type of bias in genetic association studies might lead to incorrect 497 conclusions about the usefulness of certain ... (GSTM1 and GSTT1) and lung cancer outcome Cancer Invest 2006;24:497-501 498 24 Goto I, Yoneda S, Yamamoto M, Kawajiri K Prognostic significance of germ line polymorphisms of the CYP1A1 and glutathione...

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Multi-Carrier Digital Communications - Theory and Applications of OFDM

Danh mục: Điện - Điện tử - Viễn thông

... then may be set to For the simple case of and and and are set to to the output of the IFFT is: where Of course the scaling by a factor of two is immaterial and can be dropped This real orthogonal ... concise summary of the present state of the art of the theory and practice of OFDM technology The authors believe that the time is ripe for such a treatment Particularly based on one of the author's ... effects of clipping presents results of the authors that have not yet been published elsewhere The book concludes with descriptions of three very important and diverse applications of OFDM that...

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Modelling and verification of single slope solar still using ANSYS-CFX

Danh mục: Môi trường

... vertical side of still was kept as 0.30 m, whereas the height of higher vertical side was kept 0.85 m The effective basin area of meter x meter made of GRP of m thickness Condensing cover made of toughed ... cover made of toughed glass of mm is fixed to the top of vertical walls of the stills using a rubber gasket on both sides of glass and clamp fixed iron frames made of angles A plastic pipe is ... Simulation result and experimental data In solar still, after evaporation, condensation process starts, and condensation produced by inner glass cover, and difference of temperature of water and glass...

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Tài liệu Principles And Applications Of Electrical Engineering P2 pdf

Danh mục: Cơ khí - Chế tạo máy

... for example, in three of the four quadrants of the i-v characteristic and can therefore act as sources of energy for speciﬁc combinations of voltages and currents An example of this dual behavior ... circuits and instruments EXAMPLE 2.7 Application of Kirchhoff’s Laws Problem Apply both KVL and KCL to each of the two circuits depicted in Figure 2.27 Solution Known Quantities: Current and voltage ... only of parallel or only of series elements The following examples and Check Your Understanding exercises illustrate some simple and slightly more advanced circuits that combine parallel and series...

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Tài liệu Principles And Applications Of Electrical Engineering P1 docx

Danh mục: Cơ khí - Chế tạo máy

... Principles of SR Machine 906 18.4 Single- Phase AC Motors 908 18.5 The Universal Motor 909 Single- Phase Induction Motors 912 Classification of Single- Phase Induction Motors 917 Summary of Single- Phase ... integration of electrical, electronic, and software engineering into their domain This is accomplished by making use of modern computer-aided tools and by providing relevant examples and references ... units of Table 1.3 Since, in practice, one often needs to describe quantities that occur in large multiples or small fractions of a unit, standard preﬁxes are used to denote powers of 10 of SI (and...

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Tài liệu Principles And Applications Of Electrical Engineering P2 ppt

Danh mục: Cơ khí - Chế tạo máy

... for example, in three of the four quadrants of the i-v characteristic and can therefore act as sources of energy for speciﬁc combinations of voltages and currents An example of this dual behavior ... circuits and instruments EXAMPLE 2.7 Application of Kirchhoff’s Laws Problem Apply both KVL and KCL to each of the two circuits depicted in Figure 2.27 Solution Known Quantities: Current and voltage ... only of parallel or only of series elements The following examples and Check Your Understanding exercises illustrate some simple and slightly more advanced circuits that combine parallel and series...

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Tài liệu Principles And Applications Of Electrical Engineering P1 doc

Danh mục: Cơ khí - Chế tạo máy

... Principles of SR Machine 906 18.4 Single- Phase AC Motors 908 18.5 The Universal Motor 909 Single- Phase Induction Motors 912 Classification of Single- Phase Induction Motors 917 Summary of Single- Phase ... integration of electrical, electronic, and software engineering into their domain This is accomplished by making use of modern computer-aided tools and by providing relevant examples and references ... units of Table 1.3 Since, in practice, one often needs to describe quantities that occur in large multiples or small fractions of a unit, standard preﬁxes are used to denote powers of 10 of SI (and...

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THEORY AND APPLICATIONS OF MONTE CARLO SIMULATIONS ppt

Danh mục: Điện - Điện tử

... x2 and x3 are input quanti‐ ties, u ( x1), u ( x2) and u ( x3) are their respective uncertainties and y and u ( y ) are the measurand and its uncertainty, re‐ spectively; and b) propagation of ... stating an expanded un‐ certainty for this range of mass of 0.1 g, with a coverage factor k = and a level of confidence of 95% The uncertainty of the mass due to the calibration of the balance ... Figure Comparison of the lognormal distribution fits over DS4 and DS9 (a) and over DS1 and DS4 (b) Monte Carlo Statistical Tests for Identity of Theoretical and Empirical Distributions of Experimental...

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Gravitation and cosmology principles and applications of the general theory of relativity weinberg s

Danh mục: Vật lý

...

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Fundamentals and Applications of Biophotonics in Dentistry Vol.4 doc

Danh mục: Sức khỏe giới tính

... understanding of the materials aspects of dentine and adhesives The next chapter on Dental and Oral Optics describes tools and techniques for imaging and optical properties of dentine and enamel ... some of these basic concepts to the field of dentistry to highlight some of the features and adaptation of photonics in this area Dental photomechanics provides an understanding of mechanical and ... Properties of Dental Enamel and Dentin 9.4.1 Structure of Enamel and Dentin 9.4.2 Spectral Properties of Enamel and Dentin 9.4.3 Scattering Properties of Enamel 9.4.4 Scattering Properties of Dentin...

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GraphITA 2011: Selected Papers from the Workshop on Fundamentals and Applications of Graphene pptx

Danh mục: Kiến trúc - Xây dựng

... evaluation of the Dirac energy position and the size of the band gap Concurrent with the band structure shift, the size of the band-gap increases The band ﬁtting retrieves the energy of the bottom of ... structural and chemical information reported so far are of pivotal importance to understand and give a microscopic explanation of the transport and gas sensing properties of GO Electrical Response of ... orbitals (HOMO–LUMO) of benzene This is a result of the conﬁnement of the π electrons from the delocalized state of pristine graphene to small aromatic domain of the size of a benzene ring, that...

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Production, purification, characterization, and applications of lipases pot

Danh mục: Tự động hóa

... homology with lipases of G candidum and Yarrowia lipolytica, respectively The domain of sequence conservation occurs in the N-terminal half of the protein For the resolution of isoforms via heterologous ... used as immobilized enzymes and the methods of immobilization are discussed Applications of lipases Lipases are widely used in the processing of fats and oils, detergents and degreasing formulations, ... processing, the synthesis of fine chemicals and pharmaceuticals, paper manufacture, and production of cosmetics, and pharmaceuticals (Rubin and Dennis, 1997a,b; Kazlauskas and Bornscheuer, 1998)...