importance of a factor viiic like glycoprotein expressed in capillary endothelial cells efactor viiic in angiogenesis
Basic understanding about cancer and the importance of a national surveillance and research program in Vietnam
... and contaminated drinking water (5) Cancer cells originate from normal cells in which the mutation of critical genes induces the accumulation of more mutations and the deregulation of several genes, ... therapy Chemotherapy and radiotherapy are the use of cytotoxic antineoplastic drugs or highenergy radiation, respectively; to eliminate cancer cells mainly by causing DNA damage, triggering a self-destruction ... infectious diseases, as well as advances in cancer diagnosis and social awareness of the disease Males Prostate Lung and Bronchus Urinary Bladder Colorectal Melanoma of the Skin During the three time...
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Tài liệu Báo cáo khoa học: Role of transcription factor activator protein 1 (AP1) in epidermal growth factor-mediated protection against apoptosis induced by a DNA-damaging agent doc
... expression of c-Fos and c-Jun, via the MAP kinase signaling pathway TAM67 retains the DNA binding and leucine-zipper region of c-Jun, but it lacks the transactivation domain of c-Jun (amino acids 1–122) ... was not able to activate the PtdIns3-K ⁄ Akt pathway, although it protected the cells from apoptosis induced by ADR Instead of activating this pathway, EGF stimulated the MAP kinase pathway and ... TAM2 cells, in either of which TAM67 was detected (Fig 6A) Because TAM67 lacks the transactivation domain of c-Jun (amino acids 1–122), but retains the DNA binding and leucine-zipper region of...
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Tài liệu Báo cáo khoa học: ˚ The 1.8 A crystal structure of a proteinase K-like enzyme from a psychrotroph Serratia species docx
... N-terminal pro domain is autocatalytically cleaved off when the enzyme has obtained its active conformation, and the two C-terminal domains are cleaved off by heat treatment at 50 °C An Ala-Pro-Thr ... atoms of Asp11 and Asn23 (Fig 3) in an arrangement similar to what is observed in VPRK Both PRK and VPRK have calcium bound at Ca3 SPRK also has an aspartic acid residue at position at 200, and ... proteinase K (PRK; PDB 1ic6 [20]), as search model The structure was built using a combination of auto building in ARP ⁄ wARP [39] and manual refitting of side chains using O [40] based on 2FoFc and...
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Tài liệu Báo cáo Y học: Characterization of a cloned subtilisin-like serine proteinase from a psychrotrophic Vibrio species doc
... 5¢-ATGTTAAA GAAAGTATTAAGTTGTTG-TATTGCAGC-3¢ and 5¢-AAAGTTTGCTTGGAGCGTCAAGCC-ACTGTAAG CCG-3¢, cloned into the expression vector pBAD-TOPO, transformed into the E coli Top10 strain and grown on LB agar ... PA44 The N- and C-terminal residues of the proteinase domain are underlined and residues of the catalytic triad are enlarged in bold letters proteinase or catalytic domain, and a C-terminal prosequence ... enzymes displayed identical inactivation behaviour, indicating that the same disulfide(s) are involved in maintaining the integrity of active protein structure in both wild-type and recombinant VPR...
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Báo cáo Y học: Crystal structure of the catalytic domain of a human thioredoxin-like protein pdf
... 1ERT) as a search model, then refined smoothly in alternating steps of automatic adjustment with CNS and manual adjustment with the program O [34] The final model has a final R -factor of 0.222 with a ... thioredoxin fulllength cDNA was also isolated by PCR-amplification using human fetal brain library (ClonTech) as a tem-plate PET28 vector (Novagen) and PGEX-4T vector (Amersham Pharmacia Biotech) ... acidic amino acids, if it does have some interaction with the N-terminal domain, the mechanism of regulating the catalytic activity may be similar to that of the dimer In other word, the active...
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Báo cáo khoa học: A novel serine protease highly expressed in the pancreas is expressed in various kinds of cancer cells potx
... RT-PCR analyses revealed that prosemin is expressed in various kinds of cancer cell lines and in clinical samples of ovarian carcinomas The characterization and functions of prosemin are described ... serine protease family, testisin and prostasin, are also expressed in ovarian carcinomas [31,32] Immunohistochemical analysis demonstrated the expression of prosemin in clinical ovarian carcinomas, ... Immunohistochemistry of prosemin in ovarian cancers Paraffin-embedded sections were stained with antibody directed against recombinant prosemin (A) Mucinous adenocarcinoma (B) and (C) Serous adenocarcinomas, borderline...
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Báo cáo khoa học: Functional importance of a conserved sequence motif in FhaC, a prototypic member of the TpsB/Omp85 superfamily ppt
... used as a template with the following primers : R450AUp (5¢-GACGAGTACACGGT GGCCGGATACAACCTCAGGA-3¢) and R450ALo (5¢-TC CTGAGGTTGTATCCGGCCACCGTGTACTCGTC-3¢); Y452AUp (5¢-ACACGGTGCGCGGAGCCAACCTCAAG ... visible in the electron density map and are not included in the final model Structural data are available in the Protein Data Bank database under the accession number 3NJT Overlay assay Channel analysis ... and FhaCY45 2A inserted in lipid bilayers were analysed in comparison with those of FhaCWT Initial characterization was performed by inserting a large number (about 100) of FhaC molecules in a...
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Báo cáo khoa học: Heterologous expression of a serine carboxypeptidase-like acyltransferase and characterization of the kinetic mechanism potx
... (1995) Sorting of yeast alpha-1,3-mannosyltransferase is mediated by a lumenal domain interaction, and a transmembrane domain signal that can confer clathrin-dependent Golgi localization to a secreted ... PV, Chapple C & Strack D (2002) Immunolocalization of 1-O-sinapoylglucose:malate sinapoyltransferase in Arabidopsis thaliana Planta 215, 26–32 Kozak M (1983) Comparison of initiation of protein ... (2003) Biochemical characterization of sinapoylglucose:choline sinapoyltransferase, a serine carboxypeptidase -like protein that functions as an acyltransferase in plant secondary metabolism J Biol...
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Báo cáo khoa học: Engineering of monomeric FK506-binding protein 22 with peptidyl prolyl cis-trans isomerase Importance of a V-shaped dimeric structure for binding to protein substrate docx
... with similar affinity as that of WT, the binding affinities of NNC-FKBP22 and WT to reduced a- lactalbumin were analyzed using surface plasmon resonance (Biacore) Reduced a- lactalbumin was injected ... concentration of a- lactalbumin gave a saturation curve, as shown in Fig 5B These plots showed a good fit to a single binding-affinity model and the KD value for binding of reduced a- lactalbumin to ... proteins Enzymatic activity The PPIase activity was determined using a protease-coupling assay [44] and an RNase T1 refolding assay [45] For the protease-coupling assay, chymotrypsin was used as a...
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Báo cáo khoa học: Inhibitor-mediated stabilization of the conformational structure of a histone deacetylase-like amidohydrolase pptx
... specific ligands of proteins within cells may act as molecular chaperones by stabilizing a protein conformation capable of escaping the quality control system of the cell A better understanding of the ... concentrations of Gdn-HCl Data analysis of refolding kinetics The analysis of the kinetic data is based on a linear relationship between the log of microscopic rate constants and the denaturant concentration ... specificity of class and class histone deacetylases J Biotechnol 124, 258–270 Inhibitor-mediated stabilization of HDAH 31 Ray S, Bhattacharyya M & Chakrabarti A (2005) Conformational study of spectrin in...
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báo cáo khoa học: "The grapevine guard cell-related VvMYB60 transcription factor is involved in the regulation of stomatal activity and is differentially expressed in response to ABA and osmotic stress" ppt
... (5’-GGATCCATGGGAAGGCCTCCTTGCT-3’) and Vv30R2 (5’-AAGTCTGACAGTGATGAGAGGAGC3’); Vv60F2 (5’-CTCCTTGCTGTGATAAAGTTGGTAT3’) and Vv60R2 (5’-ATTCAGGTTTTCGTACTCAAGAATG-3’) The control AtACTIN2 gene (At3g18780) ... promoter is localized to guard cells in Arabidopsis, and is down-regulated by ABA (A) 15-dayold pVvMYB30:GUS seedling (B) Magnification of leaf primordia in (A) , showing staining at the base of trichomes ... (H) and (I) Histochemical analysis of GUS expression in pVvMYB60:GUS leaves in response to ABA (H) GUS staining of stomata in a control leaf (I), GUS staining of stomata following hours of exposure...
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báo cáo khoa học: " An ABRE-binding factor, OSBZ8, is highly expressed in salt tolerant cultivars than in salt sensitive cultivars of indica rice" doc
... 5'GTCAGAAAGCTTGCCACGTGGCTGCAGTG CCATTGCCACCGGATCAGCCACGTGGCTCCA GTGCTTGCCACCGGATGACGCACAATCCCAC3' 5'CCACTTGAAGCTTACTACCGACATGAGTTCACTACCGACATGAGTTCACTACCGACATGAC GCACAATCCCAC3' 5'AGCAAGCTTTTTTATTCCCAACAATAGAAAGTCTTGTTTTATTCCCAACAATAGAAAGTCTT ... 5'AGCAAGCTTTTTTATTCCCAACAATAGAAAGTCTTGTTTTATTCCCAACAATAGAAAGTCTT GATGACGCACAATCCCAC 3' 5'GTGGGATTGTGCGTCAT3' 5'TGTAGATCTCAACAATGGGAAATGACGAAGCTGTAGTTACTCA3' 5'GAGAGATCTTTACTTGAGGCTACAGCATCAGTCGC3' 5'GGCGTGGAAACTGGTGGAGCT3' 5'CTTGAGAATTCTAAGCTCCACCAGTTTCCACGCC3' ... formation after addition of ATP (lane 1) Partial inhibition of binding was obtained with heparin (a potent inhibitor of casein kinase II, lane 2), whereas no inhibition was obtained with phenyl arsine...
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Development of a novel toll like receptor based two hybrid assay for detecting protein protein interactions and its application in the study of CD14 dimerization and FcyRIIA activation
... domain-containing adaptors and TLR signaling MyD88 is an essential TIR domain-containing adaptor for the induction of inflammatory cytokines via all the TLRs TIRAP/Mal is a second TIR domain-containing ... consisting of TGF-βactivated kinase (TAK1) and its two adaptor proteins, TAK1-binding protein (TAB) and TAB2 TAB2, an adaptor linking TAK1 to TRAF6, is associated with cell membrane under unstimulated ... cerevisi, GAL4 protein GAL4 is a transcriptional activator required for the expression of enzymes involved in galactose utilization GAL4 contains a DNA binding domain (BD) (Keegan et al., 1986) and a...
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A STUDY ON THE IMPORTANCE OF LEARNER IDEAL SELF TO THE SUCCESS IN LEARNING ENGLISH OF THE LEARNERS AT THE BORDER GUARD ACADEMY
... apparent that accessing to a wide range of technolgy brings a lot of benefits to the L2 learners when they take advantage of invaluable sources of material in the target language as well as the ... criteria in second/foreign language learning According to The National Standards for Foreign Language Learning of the United States of America, students studying a second/foreign language are necessary ... Guard Academy Border Guard Academy is an armed-force unit training officers and cadets working at the frontier areas where relations with neighboring countries take place Because it is an academy,...
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Cloning and characterization of a novel kelch like gene in zebrafish
... sacrolemma of striated muscle Table Summary of EST clones homologous to klhl iv 73 List of abbreviations LIST OF ABBREVIATIONS aa amino acid AP alkaline phosphatase arp acidic ribosomal protein ... first animal model of congenital sideroblastic anaemia (CSA) in humans The sau mutant is characterized by delayed erythroid maturation and abnormal globin gene expression, resulting in a microcytic, ... cDNA sequencing was initiated in 1991 by a landmark paper by Adams and colleagues (1991) demonstrating the richness of data that could be derived from an EST sequencing project The basic strategy...
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The use of credit scoring models and the importance of a credit culture
... estimate annual and cumulative defaults 10 Marginal and Cumulative Mortality Rate Equation MMR(t) = Total value of defaulting debt in year (t) total value of the population at the start of the year ... Empresas ICA Sociedad Controladora Grupo Televisa SA Kimberly-Clark de Mexico Telefonos de Mexico SA de CV Vitro SA de CV n .a: not available BBBBB+ BB BB+ Dec 94 n .a AAA BBBABBB AA AAA AAA BB+ ... “Distress” Zone 25 AN EMERGING MARKET CORPORATE MODEL US Bond Rating Equivalent Based on Adjusted Z” Score Model Z”=3.25+6.56X1+3.26X2+6.72X3+1.05X4 US Equivalent Rating AAA AA+ AA AAA+ A ABBB+ BBB BBBBB+...
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Economic viability of a residential building integrated photovoltaic generator in South Africa
... extensively in Europe than in Africa, with Japan, USA and China entering the market recently The PV market has not grown to expected levels in South Africa other than a few rural or far off-grid solar ... rate was used instead of the nominal interest rate The discount rate was adjusted to remove the effects of expected or actual inflation using equation (2) The market rates used and the base-case ... investment minimum acceptable rate of return was taken to be the maximum nominal interest rate charged by local commercial banks of 7% in 2009 The project is considered attractive and acceptable...
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Tài liệu Báo cáo khoa học: Local stability identification and the role of a key aromatic amino acid residue in staphylococcal nuclease refolding pdf
... et al Staphylococcal nuclease refolding investigated Two point-mutated proteins, with a single base substitution of alanine for tryptophan (W14 0A) and alanine for lysine (K13 3A) , and two truncated ... enthalpy change (DHcal) of each protein was calculated by integration of the curve covering area (Tm was taken as the curve peak point) using origin software Acknowledgements This work is partially ... Boehringer (Mannheim, Germany) Ethanol (> 99%) was obtained from Panreac (Barcelona, Spain) Urea was a product of Acros (Pittsburgh, PA, USA) The QuickchangeTM kit containing Pfu DNA polymerase,...
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Tài liệu Báo cáo Y học: Interallelic recombination is probably responsible for the occurrence of a new as1-casein variant found in the goat species potx
... TAT AGT CTA CAC GTT GTA C 3¢ 5¢ CTT AGC ATC TTC CAT GGC TTG ATC 3¢ 5¢ ATA CAC ACA AAC TCA CAA GG 3¢ 5¢ CAA CAT ATT TTA AAT AAA ATT GAC AAT 3¢ 5¢ ATA AAA ATG GTA TAC CTC ACT TGT*C 3¢ 5¢ TAA CAA ... TGG TAG GTA 3¢ 5¢ TGG CAC AAC ATT GTA CAT TCT TGG G 3¢ 5¢ GTA TGG AAG TGT GGA ATA GTT T 3¢ 5¢ GGA CAC CAC AGA TAT CCA ATA G 3¢ 5¢ CAT AAA ACT AAC AAT ACA TGT 3¢ 5¢ TAG CAG ATA TTG AAA AGG AG 3¢ ... TAC TAC AAC TT 3¢ 5¢ CAT GAA AAG CAT TTC AAA AA 3¢ 5¢ TAA AAA ACA GTG GTT ACC AA 3¢ 5¢ CTA AAG AGT ACA CTA TCC TCA C 3¢ 5¢ TTG CTG TGG TTG CCT ATC CTA 3¢ Sequencing of amplified genomic DNA fragments...
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Báo cáo khoa học: Identification and characterization of a nuclear receptor subfamily I member in the Platyhelminth Schistosoma mansoni (SmNR1) pot
... 5¢-CCGTAAGGTCACAGGTCACTCG-3¢, DR2: 5¢-CCGTAAGGTCACAAGGTCACTCG-3¢, DR3: 5¢-CCG TAAGGTCACAGAGGTCACTCG-3¢, DR4: 5¢-CCGTAA GGTCACAGGAGGTCACTCG-3¢, DR5: 5¢-CCGTAAGG TCACCAGGAGGTCACTCG-3¢ PAL0: 5¢-CGCAAGGT ... procedures Parasites The NMRI strain of S mansoni was maintained in snails (Biomphalaria glabrata) and Syrian golden hamsters (Mesocricetus auratus) Cercariae were released from infec- FEBS Journal 274 ... Journal compilation ª 2006 FEBS 391 S mansoni NR1 A B W Wu et al DNA binding domain Ligand binding domain Fig Sequence alignment (A) Alignment of DNA binding domain (C domain) and its C-terminal...
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Tìm thêm: xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 động cơ điện không đồng bộ một pha thông tin liên lạc và các dịch vụ chỉ tiêu chất lượng 9 tr 25