imaging of drugs and drug effects
Tài liệu The Acquisition of Drugs and Biologics for Chemical and Biological Warfare Defense - Department of Defense Interactions with the Food and Drug Administration doc
... review of information provided to individual recipients of IND drugs, medical monitoring and reporting of the use of such drugs, information about shipment and storage of drugs, disposition of unused ... development or acquisition of drugs and biologics for CBW defense It also recommends organizational changes in the Office of the Secretary of iii iv The Acquisition of Drugs and Biologics for CBW ... purchases of all drugs and biologicals are a small part of the commercial market, accounting for less than percent of all U.S sales of human-use drugs in 1999; government purchases of vaccines...
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Tài liệu BIOCHEMICAL TARGETS OF PLANT BIOACTIVE COMPOUNDS A pharmacological reference guide to sites of action and biological effects doc
... tens of thousands of individual primary scientific papers and reviews describing the isolation, structural characterization, pharmacological effects and biochemical targets of thousands of plant-derived ... properties Notwithstanding synthetic sweeteners, non-plant preservatives and an explosion of psychotropic drugs and other pharmaceuticals, plants are still major sources of such ameliorative and protective ... chemistry of living things) This biochemical review provides a detailed background for understanding the nature and function of the targets of plant defensive metabolites and proteins The remainder of...
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effect of drugs and alcohol on teenagers
... Result of Information Gathered: A) Source 1: Dr Nowinski's book describes specific cases of adolescent drug abuse that he has worked with He describes the different patterns of drug abuse and the ... dramatic rise in the use of marijuana and more use of stimulants, LSD and inhalants It also describes how this trend was a reversal from the recent downward patterns of drug use among teens D) ... is obvious that drug and alcohol abuse among adolescents is a prevalent and dangerous problem The use of these substances is dangerous and stupid I'm not going to be a hypocrite and say that I...
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evaluation of shape and size effects on optical properties of zno pigment
... diameters of about 200 nm and lengths of m The FE-SEM images of nanorod ZnO pigment are shown in Fig 2(g) and (h) It is found that the product is composed of well-dispersed Fig XRD patterns of the ... a large scale, and all of the nanorods have diameters of about 50 nm and lengths of 300 nm Fig (i–k) exhibits the FESEM images of nanoparticle-decorated ZnO pigment The surface of ZnO pigment ... ZnO band gap and this phenomenon is one of the most important ZnO characteristics [14] The particle sizes of scale-like and submicrorod ZnO pigments are in the optimum range of 0.25–0.45 m, and...
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Báo cáo sinh học: "High-resolution quantitative imaging of mammalian and bacterial cells using stable isotope mass spectrometry" docx
... Qualitative co-localization of DNA and RNA through simultaneous imaging of RNA and DNA Rat embryo fibroblasts were pulsed with 15N-uridine and BrdU as markers of newly synthesized RNA and DNA, respectively ... quantitative imaging of radioisotopes (such as 14C), and with high sensitivity, as shown in the pioneering work of Hindie et al [10] An example of parallel imaging at masses 14C- and 12C15N- of a whole ... and uniform carbon content The image of the 13C- ions (Figure 3e) is similar to the 12Cimage, but with a much lower count rate; the total number of counts of 13C- and of 12C- are 2.56 x 105 and...
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Báo cáo khoa hoc:" Biodegradable Nanoparticles are Excellent Vehicle for Site Directed in-vivo Delivery of Drugs and Vaccines" pptx
... delivery of vaccines, genes, drugs and other biomolecules in the body They offer enhanced biocompatibility, superior drug/ vaccine encapsulation, and convenient release profiles for a number of drugs, ... number of biomolecules, drugs, genes and vaccines to the site of interest in-vivo During the 1980’s and 1990’s several drug delivery systems were developed to improve the efficiency of drugs and ... nanoparticles and chemical binding of the drug to the polymer can be accomplished using incorporation/adsorption techniques The amount of drugs bound to NPs and the type of interaction –between drugs and...
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Báo cáo y học: "Distribution patterns of small-molecule ligands in the protein universe and implications for origin of life and drug discovery" doc
... bio-ligands Ligands and theand2 of bio-ligands and binding ATP, ligands Additionalfor file 1ownerships of metabolism-relevantADP and block numbers of for proteins folds that bindligands ligands them ... essence of drug action is the binding between drugs and target biomolecules (most of which are proteins), the ligand-protein binding features As indicated above, approximately 30% of ligands are ... features of super ligands are of significance for selecting and/ or designing multipotent agents Of course, the new strategy should be treated with wariness, because of the potential side effects of...
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Mechanical characterization of biopolymer and the effects of mechanical properties of extracellular matrix on cell behaviours
... the complexity of science and profundity of life Prof Too’s lessons extended far beyond the laboratory – from politics and current issues to virtues of integrity, honest work and humility Especially ... and gene expression In order to gain a better understanding of the effects of microenvironment on cell behaviors and vice versa, interdisciplinary approaches involving the use of principles and ... CHARACTERIZATION OF BIOPOLYMER AND THE EFFECTS OF MECHANICAL PROPERTIES OF EXTRACELLULAR MATRIX ON CELL BEHAVIORS WONG LONG HUI (B.Eng.(Hons.), NTU) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY...
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Elasticity of substitution and growth effects of taxation
... decreases the rate of return to the investment activities of the private sector and leads to a permanent decline in the rate of capital accumulation and in the rate of growth Devereux and Love (1994) ... determine the optimal paths of the shadow prices of physical and human capital (dynamic efficiency of resource allocation) The λ and µ are shadow prices of physical capital and human capital respectively ... elasticities of substitution and the growth effects of taxation Tables and 10 compare the impacts on growth of equal percentage and revenue equivalent changes in taxes Table 9: Growth Effects of Equal...
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Investigation of thickness and orientation effects on the III v DG UTB FET a simulation approach
... thickness of 12 AL and the lowest two conduction bands (Г1 and Г2) for UTB FETs with body thicknesses of 24 AL, 36 AL and 48 AL at the Г valley of VG = 0.4 V and VG = 0.8 V The effective mass of bulk ... conduction bands (Г1, Г2, Г3, and Г4) for UTB FET with body thickness of 12 AL and the lowest two conduction bands (Г1 and Г2) for UTB FETs with body thicknesses of 24 AL, 36 AL and 48 AL at ... QON QOFF ID (4.1) , where Cgs and Cgd are the intrinsic components of the capacitances, and QON(OFF) and ID are the number of charge at the ON (OFF) state and the drain current under Vdd =...
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Báo cáo y học: "Effects of typical and atypical antipsychotic drugs on gene expression profiles in the liver of schizophrenia subjects" docx
... BH and SW conception and design, analysis and interpretation of data, drafting the manuscript JS, IL and JD acquisition of data, analysis and interpretation of data RY and MW interpretation of ... typical and atypical AP drugs exert differ- Page of 15 (page number not for citation purposes) BMC Psychiatry 2009, 9:57 http://www.biomedcentral.com/1471-244X/9/57 Figure Effects of individual AP drugs ... therapeutic and side effects of typical antipsychotic (AP) and atypical AP drugs in schizophrenia have been documented [1,2] Typical APs such as haloperidol and phenothiazines induce elevation of serum...
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Báo cáo y học: " Effects of the K65R and K65R/M184V reverse transcriptase mutations in subtype C HIV on enzyme function and drug resistance" pps
... determination of specific activity and TFV susceptibility of recombinant subtype C and B HIV-1 RTs Purification, determination of specific activity and TFV susceptibility of recombinant subtype C and B ... compared to that of WT (P ≤ 0.01) and Figure of WT and mutant RTs dNTP concentration dependence of single-cycle processivity dNTP concentration dependence of single-cycle processivity of WT and mutant ... fingers domain of RT and its effect on reduction of NRTI incorporation and reduced excision is probably due to an increased rigidity of the active site and effective trapping of the dinucleoside...
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Báo cáo y học: "Comparison of Classical and Clozapine Treatment on Schizophrenia Using Positive and Negative Syndrome Scale of Schizophrenia (PANSS) and SPECT Imaging"
... in winter and early spring, and viral infections in the mother during the second and third trimesters of gestation A strong association between hypofrontality and negative symptoms of schizophrenia, ... dopamine These drugs function as antipsychotic medications and reduce delusion and hallucination By contrast, drugs such as amphetamine reinforce signal transmissions by dopamine and induce schizophrenic ... passivity and apathy, difficulty in abstract thinking, lack of spontaneity and flow of conversation, and stereotyped thinking (N1 to N7); and health concerns, anxiety, guilt, tension, mannerisms and...
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Báo cáo y học: "Advances in Molecular Diagnosis of HBV Infection and Drug Resistance"
... serological profiles fall outside of classical patterns Some key advantages and disadvantages of HBV DNA testing are presented in Table Current HBV DNA assays make use of differing technologies and can ... beacons) that decrease the number of handling steps, reduce contamination, and increase throughput and the accuracy of quantification will further enhance the utility of these assays [2,5] Given the ... necessary should the rate of emergence of resistance and the impact of such mutations turn out to be clinically relevant for therapy management Molecular Mechanisms of Drug Resistance HBV is a...
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Measurement of Color, Gloss, and Translucency of White Salted Noodles- Effects of Water Addition and Vacuum Mixing.pdf
... lightness (L*) and an increase in redness (a*) and yellowness (b*) values of raw WSN sheets from soft and hard wheat flour samples Measurements of L*, a*, and b* usually give low standard deviations ... a standard cooked noodle thickness of mm Experiment The effect of water addition and vacuum on color, gloss, and translucency for soft wheat WSN was also examined using ANOVA Translucency and ... translucency of noodles made from the soft, low-FSV wheat flour and the soft, high-FSV wheat flour (9.25% protein) were 39.75 and 43.75%, respectively The mean levels of translucency of noodles...
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Music cover, the effects of it and The attitudes of NEU’s students to Music cover in Vietnam
... understanding of “Music cover” 1.2 The real definition of “Music cover” To explain and make everybody understand clearly about “music cover” and “music copy”, the report researched Bern Convention and ... category of rock, rap, and hip-hop were covered by a lot of Vietnam’s musicians and singers Such as “Girl friend” (Avril lavigne), “The Accolade of Hip-hop” (Lee Huyn Do)… The effects of Music ... researches about one of many concepts which a lot of people don’t understand exactly which is called “Music cover” This paper is expected to give readers a deep understanding of music cover In order...
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Globalization and its effects on the development of educational service in Vietnam
... affect the demand and supply of education and training, and the effects are usually different from the effects of local investment We also distinguish between micro (firm level) and macro effects Page ... 1.4.1.3Trade and education at the micro level 1.4.2 The effects of FDI on Education 1.4.2.1 Macro effects on demand for education 1.4.2.2.Macro effects of FDI on the supply of education 1.4.2.3 Micro effects ... 1.3.3.3 Types of education 1.4 The effects of globalization on education 1.4.1 The effects of trade on education 1.4.1.1Trade and demand for education at macro level 1.4.1.2 Trade and supply of education...
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EFFECTS OF SPILLED AND STRANDED OILS ON SEAWATER INFILTRATION AND MACROBENTHIC COMMUNITY IN TIDAL FLATS
... biological effects include identifying and quantifying instances of exposure of biological communities to spilled hydrocarbons, evaluating acute, chronic and residual toxicity to organisms, and assessment ... at day 23 and 58 in the C and O simulators Fig.8 shows infiltration rate of seawater by tidal action both in the C and O simulators The infiltration rates of sweater at day 23 in the C and O simulators ... Estimation of Water Filtration and Nutrient Regeneration by Exposed Sandy Beaches Marine Environmental Research, 6, 37-47 Porter K.G and Feig Y.S (1980) the use of DAPI for identifying and counting...
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A computational study to investigate the effects of insulation and EGR in a diesel engine
... worked as a Professor and Head of department in the Department of Mechanical Engineering, Vidya Vikas Institute of Technology, Andhra Pradesh, India He has 14 years of teaching and research experience ... are larger than that of 400°CA and the eddy formed in right half of bowl is larger than that of left half of bowl At 400°CA, the shape of high temperature regions for baseline and adiabatic with ... Because of shortage of oxygen in the charge of cylinder in the EGR case, amount of burnt fuel and consequently accumulated heat release are less than the others Figure 10 shows the effect of insulation...
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