i extend my deepest gratitude to my supervisor dr kevin tan for giving me the opportunity to work in hi
Pathobiological studies of zoonotic blastocystis subtypes using in vitro model systems
... Interleukin IMDM Iscove’s modified Dulbecco’s medium iNOS Inducible nitric oxide synthase Min Minute ml Milliliter MLC Myosin light chain MLCp Phophorylated myosin light chain MLO Mitochondria like ... broadspectrum antibiotics 2.3.17 Cysteine protease inhibition causes parasite death 2.4 Discussion CHAPTER VARIATIONS IN NITRIC OXIDE SUSCEPTIBILITY AND POTENTIAL FOR EPITHELIAL INOS INHIBITION BETWEEN ... but it does help in predicting treatment outcomes Lastly, epithelial barrier dysfunction induced by pathogenic and metronidazole-resistant Blastocystis was significantly inhibited by inhibition...
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Báo cáo Y học: Incorporation of 3-nitrotyrosine into the C-terminus of a-tubulin is reversible and not detrimental to dividing cells potx
... nitrotyrosine is incorporated as such into the C-terminus of the a-tubulin subunit, by the same mechanism as tyrosine Capability of nitrotyrosinated tubulin to assemble into microtubules in vitro Eiserich ... conditions in which protein synthesis was inhibited by more than 95%, the decay of nitrotyrosinated tubulin was identical to that shown in Fig (day 2–3), while the tyrosinated tubulin form increased ... brain extract For monitoring the tubulin isospecies, we used radioactive amino acids as well as specific antibodies After incorporation of [14C]nitrotyrosine or [14C]tyrosine into tubulin, the...
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Báo cáo y học: " Draft genome sequence of the Daphnia pathogen Octosporea bayeri: insights into the gene content of a large microsporidian genome and a model for host-parasite interactions" pps
... in this studyidentifiedotherwise identified inexamples ofproteinswith assigned functions genome Enc.80O bayeriand1we identified in identifiedcounterparts that arebayeri bayeri proteinsassignmentwe ... so in this case our study simply corroborates previous findings The remainder of these eukaryotic proteins stood out for being involved in important functional processes In total, 14 are involved ... genome If this is the case, genome size variation in microsporidia could also be a consequence of variation in the size of telomeres This prediction is supported by the recent acquisition in our...
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Things I Learned The Hard Way: The business adventures of a freelancer
... unite with others (consider co-working, join certain business groups, ) Monday June 12 @matuvu Measure, Evaluate measure everything you your time, your projects your profits learn from your mistakes ... Network it is the best way to find exiting new clients or to find new partners or to fun stuff Monday June 12 @matuvu Surround Yourself the best way to loose your uncertainties is to talk to colleagues ... @matuvu Hi, I m Ine, a (web)designer & photographer, currently based in Ghent, Belgium (I m also lead designer of Emphas.is) I have been a freelancer since 2000 And I made loooooads of mistakes during...
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Báo cáo y học: "The NFI-Regulome Database: A tool for annotation and analysis of control regions of genes regulated by Nuclear Factor I transcription factors" pdf
... contain known binding sites for p53 and therefore it is listed here only as a gene Clicking on the gene link in the search menu will display binding site information for the gene From this page ... known cis-regulatory sites within a single database is daunting, therefore restricting our analysis to NFI-site containing regulatory regions provides us with a defined starting point for our ... containing AP-4 binding sites, aligned by ATG as The height of the bar indicates the number of binding sites of each type within the bin of 1000 bp Bins can be adjusted in size Proposed uses of the...
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The Marketing Strategy of a multinational join stock company.doc
... distribution, which is a major abstaining to the expansion of large-scale retailing in developing countries 1.4 The marketing mix strategies Philip Kotler, in his book “Principles of Marketing”; ... company is now considering expanding, as it is looking for more sources of capital Some employees in a multinational join stock company are thinking of investing in the company by buying its shares ... application to maintain successes in a long run In this thesis, the write also has suggested some of solutions to improve the marketing strategies for a multinational join stock company in the time...
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Tài liệu Issues Involved When Updating the Primary Key of a Parent Row pptx
... cascaded to the Orders table This is the default Checked, meaning that changes to the CustomerID primary key value in the Customers table are cascaded to the Orders table In addition, the settings ... contains a row with the CustomerID of J6COM, and because of the foreign key you can't change the CustomerID in the parent Customers table Even if you tried to change the CustomerID in ordersDT first ... Even if you tried to change the CustomerID in ordersDT first, you'd run into the same exception Conclusion The enforcement of the constraints in the previous three examples is correct, and they...
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Tài liệu Báo cáo khoa học: Involvement of two positively charged residues of Chlamydomonas reinhardtii glyceraldehyde-3-phosphate dehydrogenase in the assembly process of a bi-enzyme complex involved in CO2 assimilation doc
... residue is not directly involved in the interaction with the small protein It is likely that the introduction of the negative charge destabilizes the S loop, thus indicating that this loop, in ... proteinprotein interactions (Fig 1A) Hydrophobicity distribution patterns were also analyzed using a simple method to identify residues potentially involved in proteinprotein interactions [13] This method ... that the conserved residue arginine 64 of C reinhardtii PRK is involved in the interaction of this enzyme with the GAPDHCP12 subcomplex This report describes the behaviour of four GAPDH mutants to...
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Tài liệu Báo cáo khoa học: "Learning the Latent Semantics of a Concept from its Definition" pptx
... Linguistics Weiwei Guo and Mona Diab 2011 Semantic topic models: Combining word distributional statistics and dictionary definitions In Proceedings of the 2011 Conference on Empirical Methods in ... 1997 Finding predominant word senses in untagged text In Proceedings of International Conference Research on Computational Linguistics Linlin Li, Benjamin Roth, and Caroline Sporleder 2010 Topic ... Association for Computational Linguistics Ravi Sinha and Rada Mihalcea 2007 Unsupervised graph-based word sense disambiguation using measures of word semantic similarity In Proceedings of the IEEE International...
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Tài liệu Báo cáo Y học: Thermostability of manganese- and iron-superoxide dismutases from Escherichia coli is determined by the characteristic position of a glutamine residue pdf
... activities with either iron or manganese in the reconstituted enzyme [27] Double mutations have been introduced into P gingivalis and E coli SODs with the intention of altering their metal specificities ... that Q77 bonding to N74 also disrupts the active site residues, causing a shift in the position of Y34 and a twist in the ring of the metalbinding H81 Thermostability is not a new phenomenon amongst ... different for FeSOD and MnSOD enzymes [11] Bound azide is contained within a pocket formed by no less than six ˚ ˚ residues all within A (azide N1 comes within 2.1 A of the metal ion) Azide binding...
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NATIONAL REPORT OF MALAYSIA ON THE FORMULATION OF A TRANSBOUNDARY DIAGNOSTIC ANALYSIS AND PRELIMINARY FRAMEWORK OF A STRATEGIC ACTION PROGRAMME FOR THE BAY OF BENGAL potx
... Sedimentation The rapid pace of urbanization, indiscriminate destruction of rainforests and catchments for the establishment of new townships and industrial sites have resulted in the high sedimentation ... Malaysia participates actively in the regional and international fora on environment and has good working relationships with a number of international organizations Some of these linkages include ... plantations in Kalimantan and Sumatra and with palm oil prices expected to be bullish, the torching of forest lands in Indonesia could be on an industrial scale in the future The monitoring, control,...
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The Making of a European Constitution Judges and Law Beyond Constitutive Power docx
... VII Bringing politics back in: an ‘illiberal’ conclusion Constitutional mo(u)rning 13 14 Retelling the legal integration story Introduction: law’s proprium and the inadequacy of interdisciplinarity ... invented, including photocopying and recording, or in any information storage or retrieval system, without permission in writing from the publishers British Library Cataloguing in Publication Data ... integration: constituting society beyond the market IV.1 The limits to corporatist dissolution: constraining the self-defining European polity within the European market IV.2 The limits to organic interconnection:...
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Báo cáo khóa học: Mutational and computational analysis of the role of conserved residues in the active site of a family 18 chitinase docx
... in the family 18 chitinase from Coccidioides immitis was found to be in the ÔdownÕ position in the apoenzyme and in the ÔupÕ position in the complex with allosamidin [45], which is analogous to ... residues discussed in this report In the free enzyme, Asp142 is in the ÔdownÕ position, interacting with Asp140 Upon substrate-binding, Asp142 moves into the ÔupÕ position and interacts with the ... somewhat drastically, increased upon substrate-binding The D142N mutant is interesting because it retains significant activity (suggesting that a wildtype-like catalytic mechanism still applies) while...
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Báo cáo khoa học: "Techniques to incorporate the benefits of a Hierarchy in a modified hidden Markov model" pptx
... (O) for each internal state; II) apply the forward algorithm to estimate the state probabilities (¯ for the three b) transformed states; III) reform the transition matrix by including estimated ... Hierarchical Hidden Markov Models for Information Extraction In Proceedings of the 18th International Joint Conference on Artificial Intelligence, Acapulco, Mexico, Morgan Kaufmann A J Viterbi ... transformed into sin , sstay , (2) ¯ (i) = max πj × Oj,t , ¯ bin,t j=1 Ni where πj represents the transition probabilities of entering child state Sj The second probability of staying in state Si...
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Báo cáo Y học: Subsite mapping of the binding region of a-amylases with a computer program ppt
... (BCF), which gives information about the subsite-binding energy By using BCFs for a series of oligomeric substrates, it is possible to calculate the subsite binding energy for each subsite on the ... data possibilities Simple usage WINDOWS compatible, help in the menu Note is used for saving, editing and printing calculated data Graphical illustrations (minimization, subsite map) make the results ... kJÆmol)1) might indicate a binding subsite, but this is not convincing at all The computer modeling on the two different maltooligosaccharide series resulted in the same subsite map for PPA As it can...
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Báo cáo Y học: Crystal structure of the catalytic domain of a human thioredoxin-like protein pdf
... amino acids, if it does have some interaction with the N-terminal domain, the mechanism of regulating the catalytic activity may be similar to that of the dimer In other word, the active site ... human thioredoxin, 1–105 Oxidized human thioredoxin, 1–105 E coli thioredoxin, 1–108 Thioredoxin in chlamydomonas reinhardtii, 1–107 Thioredoxin domain of protein-disulfide isomerase, 1–120 1ERT ... and its N-terminal domain have the thioredoxin-like reductase activity To investigate the thioredoxin-like reducing activity of hTRXL, we expressed recombinant hTRXL and human thioredoxin as His-tagged...
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Báo cáo Y học: Kinetic and biochemical analyses on the reaction mechanism of a bacterial ATP-citrate lyase ppt
... observed with the enzyme in terms of citrate binding, as well as inhibition by ADP In addition, our results indicate the steps that govern the nucleotide dependency of the enzyme and the inhibition ... phosphorylation of the AclA subunit, as well as stabilizing its structure Examination of the inhibitory effect of ADP As an increased ratio of ADP towards ATP signicantly inhibits Cl-ACL activity, we investigated ... subunits, indicating the importance of the b subunit in the nucleotide preference [26] As alignment of Cl-ACL with Ec-SCS identied the corresponding residues for the interaction to nucleotides in...
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Báo cáo " Influence of laser parameters on the stationary operation of a two-mode random micro laser " pdf
... increased and the one of mode n is diminished (see Fig 1a) However, when the gain coefficient α augments, the transformation of photon densities is inverse (see in Fig 1b) This reveals that the increase ... coefficient β1 varies Fig 2b Loss coefficient β2 varies 3.3. Field coupling coefficients i, j Analogously, the influence of field coupling coefficients θ12 and θ21 on the photon densities is inverse ... transformation of loss coefficient, the mode photon density varies clearly and quickly Therefore, loss coefficient takes the important role in the process transformating the mode photon density in...
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Đề tài " On the Julia set of a typical quadratic polynomial with a Siegel disk " ppt
... when θ is of bounded type In this case, the Siegel disk ∆θ is a quasidisk in the sense of Ahlfors and its boundary contains the finite critical point The idea behind the proof of Theorem A is to replace ... The basin of attraction of in nity for Pθ should correspond to a similar basin A(∞) for Fθ (which is the immediate basin of attraction of in nity for fθ ) By imitating the case of polynomials, ... extension H : D → D? Question Under what optimal arithmetical condition EDI on θ does the model Fθ admit an invariant Beltrami differential satisfying David’s integrability condition in the plane? It...
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