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gt and gt compounds derived from different machine learning methods by using the independent validation set in this work

Machine learning approach in pharmacokinetics and toxicity prediction

Machine learning approach in pharmacokinetics and toxicity prediction

Cao đẳng - Đại học

... accuracies of GT+ and GT- compounds derived from different machine learning methods by using the independent validation set in this work 177 Table 8.3 Molecular descriptors selected from the RFE ... QSPkR models on independent validation set 114 Table 6.1 Number of compounds in the training, independent validation, modeling training and modeling testing sets for the inhibitors/substrates ... controlled by multiple mechanisms Thus it is of interest to examine the potential of using a larger number and more diverse groups of compounds and non-linear machine learning methods in improving the...
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BRANDS ARE BUILT IN THE CONSCIOUSNESS OF THE RECEIVER, NOT BY THE COMPANY potx

BRANDS ARE BUILT IN THE CONSCIOUSNESS OF THE RECEIVER, NOT BY THE COMPANY potx

Tự động hóa

... strong and, in the future, very successful position by investing in their brands Which is something we’re also doing.” “To have a focus on the whole and understand the interplay between many different ... nding what distinguishes them and makes them interesting and thus makes people want to choose them,” he says The challenge in all branding work is to whittle out what is the unique DNA of the ... of the most famous and tradition-bound chateaux in the Bordeaux region have begun selling their wines as bag -in- box t he ingenuity involved in wiping our behinds has included everything from...
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Báo cáo hóa học:

Báo cáo hóa học: " The synergistic effect of IFN-α and IFN-γ against HSV-2 replication in Vero cells is not interfered by the plant antiviral 1-cinnamoyl-3, 11-dihydroxymeliacarpin" pptx

Hóa học - Dầu khí

... the capacity of human IFNα and/ or IFN-γ to inhibit the replication of HSV-2 strains MS and G was initially performed in a plaque reduction assay The concentration of IFN-α and IFN-γ used in the ... MS-infected cultures and 2 -and 3-fold in G infected cultures respectively (Figure 1e and 1f) In HSV-2 infected cultures treated with combination of IFN-α and IFN-γ the inhibitory effect was different between ... dependent manner The combination of each IFN with CDM increased in log the antiviral effect but without altering the kinetics of the inhibition observed All these results suggest that the presence...
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Báo cáo hóa học:

Báo cáo hóa học: " Effects of rehydration nutrients on H2S metabolism and formation of volatile sulfur compounds by the wine yeast VL3" docx

Hóa học - Dầu khí

... GCTGCCGCTGAAGGTAAG CGAAGATGGAAGAGTGAGAGTC OPT1 TGTCCCGATTGGTGGTATTTAC MET10 CACTCACGTTCCATCCACTACC GTGTTGGTTAGTCATTGCTTCC CACTCACGTTCCATCCACTACC IRC7 CCTGGATTTGGCTGCTTGG AGAACCTTTGTAGTCACGAACC ... biosynthesis of the sulfur-containing amino acids and the sulfate assimilation pathway (Figure 2c) Addition of DAP, on the other hand, upregulated approximately 67% of the genes involved in sulfate ... still, further study is needed in order to link between the two effects and to understand the factors affecting H S during fermentation H2S is formed during fermentation as an intermediate in the biosynthesis...
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báo cáo khoa học:

báo cáo khoa học: " Awareness of the need for safe storage of Methadone at home is not improved by the use of protocols on recording information giving" doc

Báo cáo khoa học

... given by the clinic, 18 (10.3%) by the pharmacy, (0.6%) by a drug agency and (3.4%) by other sources Advice given by the clinic 40 (10%) sets of patients' notes were randomly selected from the ... provision of information on safety issues was poor The audit suggested improvements in the information giving process by adopting a standard policy The aim of this project was to re-audit the information ... http://www.harmreductionjournal.com/content/5/1/15 and the patients' acceptance of the advice It also evaluated the impact of the changes suggested by the original audit Methods Criteria The following criteria for the adequacy of information...
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DIRECT TREATMENT OF POLLUTED RIVER WATER BY THE MULTI-SOIL-LAYERING METHOD

DIRECT TREATMENT OF POLLUTED RIVER WATER BY THE MULTI-SOIL-LAYERING METHOD

Môi trường

... water and treated water, we determined the daily fluctuation of them by those sampling at hour interval in 7th to 8th November 1999 Soil and zeolite were sampled from the MSL systems after finishing ... for the other systems using smaller size of zeolite during the period with hydrologic loading rates lower than m3 m-2 day-1, they caused clogging within months after the loading rate was increased ... contact of inlet water and materials inside the system and filtering ability of SS in inlet water were improved by using smaller zeolite for those MSL systems However, those MSL1, and started...
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Cadmium Removal by the Hydroponic Culture of Giant Reed (Arundo donax) and Its Concentration in the Plant

Cadmium Removal by the Hydroponic Culture of Giant Reed (Arundo donax) and Its Concentration in the Plant

Môi trường

... was removed within days in every run Assuming the zero-order kinetics, the average cadmium removal rates within the days calculated from the linear approximations of the plots in Fig were estimated ... concentration in giant reed as a result of Run 6, indicating that the cadmium was highly concentrated in the rhizome The transportation index, Ti, indicates the ability of the plant to translocate the ... cadmium, and is synthesized from glutathione (GSH) Inouhe et al (1994) reported that the cadmium binding complex containing PCs has an important role for the cadmium-tolerance of seedlings of...
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ENGLISH ADVERBS OF MANNER AND TYPICAL ERRORS MADE BY THE STUDENTS AT LE HONG PHONG SPECIALISED SECONDARY SCHOOL, NAM DINH CITY

ENGLISH ADVERBS OF MANNER AND TYPICAL ERRORS MADE BY THE STUDENTS AT LE HONG PHONG SPECIALISED SECONDARY SCHOOL, NAM DINH CITY

Khoa học xã hội

... you *The “split infinitive”: In informal English, adverbs of manner are often placed immediately after the word to of an infinitive In this case, the infinitive is referred to as a split infinitive ... analyzed in order to find out typical errors and their causes The findings of the study show that most of the errors are made in forming adverbs of manner and distinguishing between adverbs and adjectives ... control Right at the beginning they received some instruction by the teacher on how to display the answer The students were encouraged to the test by themselves and no cheating was allowed Also,...
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Tài liệu The Insider’s Guide to PR: Chapter 6 PR IN PRACTICE The following case studies are examples of PR pptx

Tài liệu The Insider’s Guide to PR: Chapter 6 PR IN PRACTICE The following case studies are examples of PR pptx

Tiếp thị - Bán hàng

... across the country (The feedback from these groups determined the timing and content of the schools packs underpinning the schools programme) • Develop two cartoon characters, ‘Safe-T’ and the ‘H-Squad’ ... position the company as dynamic; leading the way out of the dot.com investment gloom • To distance the company from the harsh media criticism surrounding internet investment that was occurring at the ... range of online and traditional media, bulletin boards and chat rooms, advising the client of shareholder sentiment and emerging issues in the marketplace and react accordingly • Manage and advise...
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Tài liệu Art of Surface Interpolation-Chapter 5:Solving special tasks In the next sections there are examples of interpolation problems, ppt

Tài liệu Art of Surface Interpolation-Chapter 5:Solving special tasks In the next sections there are examples of interpolation problems, ppt

Kỹ thuật lập trình

... following two keywords COORD and ZCORN, which have to be included in the input data file The keyword COORD introduces the data describing coordinate lines and the keyword ZCORN introduces the data ... linear interpolation, the domain of the triangulation method is restricted to the convex envelope of the points XYZ To restrict the domain of the function constructed using the ABOS method by ... function set by the boundary (red rectangle) exceeds the domain defined by the points XYZ The boundary was set so that the aerodynamic resistance could be estimated aside the data on the left and...
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A CASE STUDY ON COMMON PROBLEMS IN LEARNING BUSINESS ENGLISH VOCABUALRY IN THE BOOK “BUSINESS BASICS” FACED BY THE 1ST YEAR STUDENTS AT VIETNAM UNIVERSITY OF COMMERCE, AND SOME SUGGESTED SOLUTIONS

A CASE STUDY ON COMMON PROBLEMS IN LEARNING BUSINESS ENGLISH VOCABUALRY IN THE BOOK “BUSINESS BASICS” FACED BY THE 1ST YEAR STUDENTS AT VIETNAM UNIVERSITY OF COMMERCE, AND SOME SUGGESTED SOLUTIONS

Kinh tế - Quản lý

... VUC to find out what teaching methods they are using, what problems they find from their 1st year students in vocabulary learning, and some recommendations made by them This is to support the two ... who are working with these students were invited to participate in an interview held by the researcher They are both male and female, aging from 25 to 50 and have worked with the book “Business ... improve the students’ vocabulary learning Scope of the study This study is limited to the area of investigating in English vocabulary learning faced by the first-year students in VUC when working...
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Tài liệu Báo cáo

Tài liệu Báo cáo " Survey of WO3 thin film structure built on ito/glass substrates by the Raman and xrd spectroscopies" doc

Báo cáo khoa học

... hours The crystalline structure of WO3 thin films was investigated by XRD patterns using Cu Kα radiation at 1.5406 Ǻ wavelength and Raman spectroscopy using He – Ne excitation (632.8 nm) In order ... this thermal stress, in order to survey WO3, we have combined the results from both XRD and Raman spectrum investigations Beside that, from XRD patter, the grain size of WO3 film were determined ... However, the absence of 950 cm-1 refuses that assumption The origin of this peak will be focused on in this paper Experimental In this research, ITO and WO3 layers were prepared by magnetron sputtering...
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Tài liệu Produced jointly by the British HIV Association (BHIVA), the British Association for Sexual Health & HIV (BASHH) and the Faculty of Family Planning & Reproductive Health Care doc

Tài liệu Produced jointly by the British HIV Association (BHIVA), the British Association for Sexual Health & HIV (BASHH) and the Faculty of Family Planning & Reproductive Health Care doc

Sức khỏe phụ nữ

... spermicidals) after intercourse and inseminating this into the woman’s vagina using a syringe and, if preferred, a quill This process of selfinsemination should be discussed fully with the couple and advice ... occurs, as evidenced by individual case observations, by the usual finding of invasive cancer within surrounding AIN3, and the overwhelming HR HPV ‘smoking gun’ evidence However, the frequency of ... or ethynodiol diacetate and mainly work by thickening cervical mucus, and by a lesser effect on the endometrium The newer desogestrel POP works by inhibiting ovulation in the majority of women...
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Tài liệu Cancer Pain Management: A perspective from the British Pain Society, supported by the Association for Palliative Medicine and the Royal College of General Practitioners docx

Tài liệu Cancer Pain Management: A perspective from the British Pain Society, supported by the Association for Palliative Medicine and the Royal College of General Practitioners docx

Sức khỏe giới tính

... of the psychosocial factors influencing the experience of pain will include: • the patient’s understanding of their condition • what the pain means to the individual and their family • how the ... and multimodal, using combination therapies including interventions where appropriate, which is tailored to the needs of an individual, with the aim of optimising pain relief while minimalising ... to reduce pain intensity • Cancer pain is often very complex, but the most intractable pain is often neuropathic in origin, arising from tumour invasion of the meninges, spinal cord and dura, nerve...
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Tài liệu The Role of BCG Vaccine in the Prevention and Control of Tuberculosis in the United States: A Joint Statement by the Advisory Council for the Elimination of Tuberculosis and the Advisory Committee on Immunization Practices docx

Tài liệu The Role of BCG Vaccine in the Prevention and Control of Tuberculosis in the United States: A Joint Statement by the Advisory Council for the Elimination of Tuberculosis and the Advisory Committee on Immunization Practices docx

Sức khỏe giới tính

... used vaccines were derived from the original M bovis strain, they differ in their characteristics when grown in culture and in their ability to induce an immune response to tuberculin These variations ... explore the sources of the heterogeneity in the efficacy of the BCG vaccine reported in the individual studies Using a model that included the geographic latitude of the study site and the data ... States, the Tice strain, was developed at the University of Illinois (Chicago, Illinois) from a strain originated at the Pasteur Institute The Food and Drug Administration is considering another...
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Tài liệu TRANSFER CREDIT SERVICES GUIDE: Produced by the Office of the Registrar ppt

Tài liệu TRANSFER CREDIT SERVICES GUIDE: Produced by the Office of the Registrar ppt

Ngân hàng - Tín dụng

... selecting My Degree Audit (EVAL) from the menu on the left 2) Choose a course from an outside institution that you think would fulfill your outstanding requirement*, and then have the Information ... students, including those transferring from other schools, are required to complete a minimum of 60 credits for the degree and 48 credits for the diploma at Berklee in order to graduate from the college ... online at my.berklee.net by clicking on Student Services, then selecting View Transcript from the menu on the left You can then compare your transcript/earned credits to the Grids by Major link...
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Tài liệu cwnaTMCertified Wireless Network AdministratorOfficial Study GuideEndorsed by the Wireless LAN AssociationIndustry Approved!TMExam PW0-100Objective-by-Objective coverage of the CWNA certification examVendor-neutral wireless network trainin pptx

Tài liệu cwnaTMCertified Wireless Network AdministratorOfficial Study GuideEndorsed by the Wireless LAN AssociationIndustry Approved!TMExam PW0-100Objective-by-Objective coverage of the CWNA certification examVendor-neutral wireless network trainin pptx

An ninh - Bảo mật

... Networking Finally, if you are stepping into the networking world for the very first time, please make sure you have a basic understanding of networking concepts, and then jump right in! The wireless ... rest of the pack by learning wireless networking to complement your existing networking knowledge The wireless LAN industry is growing faster than any other market segment in networking Many new ... operational standards and drafts in the United States that are created and maintained by the Institute of Electrical and Electronic Engineers (IEEE) These standards are created by groups of people...
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Tài liệu Audit of Contract Management by the Sectors doc

Tài liệu Audit of Contract Management by the Sectors doc

Kế toán - Kiểm toán

... audit standards set out in the TBS Internal Audit Policy and the Institute of Internal Auditors (IIA) Standards for the Professional Practice of Internal Auditing, which require the setting of ... abbreviated) The payment officer in central accounting could then sign or initial the statement to certify it In this way, instead of simply seeing initials in several places on the invoice without knowing ... irregularities In certain cases, the deliverables specified in the statement of work had not been received, either in whole or in part and in others, we found that there was a risk of developing an employer/employee...
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