geographical analysis of disease in small areas using hierarchical bayesian models mapping men s lung cancer mortality in galicia spain
Báo cáo khoa học: Functional analysis of mutations in UDP-galactose-4epimerase (GALE) associated with galactosemia in Korean patients using mammalian GALE-null cells pdf
... proteins were also observed in the cytoplasm, as seen for the wild-type protein Similar staining patterns were observed in other human cell lines, including hepatoma Hep3B cells and fibroblast 2fTGH ... 2fTGH cells (data not shown), suggesting that mislocalization of the mutant proteins was not cell-type-specific Aggresomes are structures formed in the presence of misfolded proteins and contain components ... behaved in a manner similar to the original CHO cells (data not shown), suggesting that the mild defects did not affect this phenotype This is consistent with previous results in yeast showing a steep...
- 10
- 511
- 0
Báo cáo khoa học: Functional analysis of disease-causing mutations in human galactokinase potx
... step of catalysis That five of the 10 disease- causing mutations resulted in insoluble protein in E coli suggests that in these cases protein folding and/or stability of the folded state may be ... the binding of galactose at some point in the reaction Modest changes in Km,ATP are seen in H44Y and R68C That H44 in uences the binding of both substrates suggests that the binding sites are ... the most likely kinetic mechanism for GALK1 is an ordered ternary complex one, in which ATP binds first Using ADP as an inhibitor was not possible using the enzyme-linked assay system described...
- 8
- 414
- 0
Báo cáo khoa học: Functional analysis of disease-causing mutations in human UDP-galactose 4-epimerase pot
... inhibitors in the solutions used during purification Kinetic analysis of disease- causing mutations The steady-state kinetic parameters of each of the nine disease- causing mutant proteins were determined ... compilation ª 2005 FEBS D J Timson Disease- causing mutations in human GALE Fig Crosslinking of wild-type and disease- causing mutants of UDP-galactose 4-epimerase (GALE) Crosslinking was carried out with ... exist in solution as a homodimer [1] One possible explanation for the in vivo effects of the disease- causing mutations is a failure to form dimers However, cross-linking using N(3-dimethylaminopropyl)-N¢-ethylcarbodiimide...
- 8
- 424
- 0
Báo cáo khoa học: "Clinical Analysis of stereotactic body radiation therapy using extracranial gamma knife for patients with mainly bulky inoperable early stage non-small cell lung carcinoma" pot
... or progressive disease were classified as having stable disease for weeks Overall efficacy consisted of CR and PR evaluated at four weeks after treatment was finished The major indexes of long-term ... response (PR), stable disease( SD), or progressive disease( PD) as judged according to CT image According to Response Evaluation Criteria in Solid Tumors (RECIST) (WHO 2000 version) [19], a CR was ... metastases The rest of patients with tumor progression were only given symptom relieving treatment and supportive treatment Factors influencing outcome of treatment The Univariate analysis showed...
- 7
- 364
- 0
báo cáo khoa học: "Real-time imaging and analysis of differences in cadmium dynamics in rice cultivars (Oryza sativa) using positron-emitting 107Cd tracer" ppsx
... viewpoints of physiological and genetic studies [2] A dose-dependent process exhibiting saturable kinetics has been shown in the roots of several graminaceous crops, including rice [35] The saturable ... the PETIS imaging NS and SIT processed the imaging dataset obtained by the PETIS SI1 drafted the manuscript with the assistance of NS and SF All authors discussed the results and commented on ... storage in root vacuoles All high-Cd indica cultivars used in this study showed a loss of function of OsHMA3, resulting in failure to sequester Cd in their root vacuoles [9, 10, 28] Our results indicate...
- 38
- 282
- 0
Báo cáo sinh học: " The analysis of disease biomarker data using a mixed hidden Markov model (Open Access publication)" ppt
... the IMI+ cows increased, as discussed in the sensitivity analyses below 3.2 Sensitivity analyses The robustness of the HMM approach was assessed by computing the biases in the estimates over a wide ... biomarkers assumed to be dependent upon the genetic make-up of the cows The t of the HMM was assessed on simulated data based on parameters obtained in a survey of clinical mastitis cases Bayesian estimates ... estimates of the parameters were obtained using the Gibbs sampler Finally, limitations and possible extensions of the current approach are discussed MATERIALS AND METHODS Throughout, k indexes the individual...
- 19
- 388
- 0
An analysis of errors in using English articles by 10th graders at Quảng Xương III High School, Thanh Hóa Province = Phân tích lỗi sử dụng mạo từ tiếng Anh của
... these type of exercises as the students often make these errors: 32 +errors in using indefinite articles +errors in using definite article for specific things +errors in using articles for definite ... phrases, using the in generic singular noun phrases where English would require a, using indefinite article for specific singular noun phrases, using Ø instead of the with the only one of sometthing, ... for definite or indefinite meaning +errors in misusing articles (such as, using the for generic plural or uncoutable noun phrases, abstract nouns, mass nouns, using the instead of Ø with generic...
- 50
- 522
- 2
A GEOGRAPHICAL ANALYSIS OF AIR HUBS IN SOUTHEAST ASIA
... issues and themes discussed in this thesis Finally, the concluding chapter reviews and summarizes the issues raised in this thesis and highlights some of the results and conclusions of this study ... uncertain outlook in the wake of skyrocketing fuel prices, he A Geographical Analysis of Air Hubs in Southeast Asia stressed the Singapore government s priority in safeguarding Changi Airport s status ... “other” side of air 12 A Geographical Analysis of Air Hubs in Southeast Asia hub development from the user s perspective The findings from this case study will also add an empirical dimension to issues...
- 191
- 537
- 0
Analysis of changes in earning distributions of urban chinese economy using quantile regression
... develop this thesis In addition, I wish to express my sincere thanks to A/Professor Liu Haoming, who has given me a lot of valuable suggestions for improving this thesis i Table of Contents SUMMARY ... is that the increasing demand for highly skilled labor, which seems to be caused by the spread usage of computers, raises wages for high-skilled workers This paper studies the change in earning ... concludes Figures (all of them are produced with software “R”) and tables are presented in the Appendix 2 Modeling 2.1 Ordinary Least Squares Linear regression is mostly used in modeling and analyzing...
- 39
- 164
- 0
Change detection and analysis of shoreline in the northeast of taiwan using remotely sensed data
... detection and analysis of shoreline in the northeast of Taiwan using remotely sensed data Assoc Prof Tang-Huang Lin and MSc Nguyen Van Hieu Abstract: This study focuses on the use of remotely sensed data ... to in coastal environment In assessment of coastal change, in a given period of time, the integration of remote sensing data with other geodata into Geographical Information Systems (GIS) is a ... images, and statistical tables, and other related documents And users have missions as designing of standards, updating data, analyzing information, and supplementing data for system Applications...
- 51
- 1,056
- 0
Báo cáo y học: " Mutation Analysis of hCDC4 in AML Cells Identifies a New Intronic Polymorphis"
... confirmed by sequencing DNA samples of 51 healthy individuals Interestingly, this SNP had not yet been registered in any SNP databases despite of its high frequency of 20% in samples of patients with ... mutations of the hCDC4 gene may not play a pivotal role in the pathogenesis of AML This supplements studies which have discovered hCDC4 mutations in subsets of solid tumors and implies that mutations ... products in the reference sequence (negative control) These fragments corresponded to the lengths of the sequence surrounding the detected mutation in exon Similarly, analysis of samples containing...
- 4
- 393
- 0
CONSOLIDATION ANALYSIS OF EMBANKMENT IN STAGED CONSTRUCTION ON SUBGRADE SOFT SOIL
... computably solved and predictably evaluated the behaviour and stability of the structures The main purposes of FE-analyses are the determination of stresses including pore pressures, of stress/strain ... Development of excess pore pressure during staged constructions (at point B) As soon as each filling layer is placed, excess pore pressure immediately increases and after that gradually dissipates ... Type Unsaturated soil weight, unsat RESULTS OF ANALYSIS Stress-strain behaviour The total stress distribution in principal (major and minor) directions at the end of the last construction is drawn...
- 7
- 377
- 0
Spectral analysis of total ozone column variability using TOMS data over Baghdad, Iraq
... the possible linked between weather elements and TOC in order to forecasting the daily ozone This study shows that its necessary to start or continue regular observation of TOC in many parts of ... 49 C in the summer months and several stations have records of over 53 C The summer months are marked by two kinds of wind phenomena The southern and southeasterly sharqi, a dry, dusty wind with ... available from stations in the foothills and steppes south and southwest of the mountains suggest mean annual rainfall between 320 and 570 millimeters for that area Rainfall in the mountains is more...
- 6
- 549
- 1
A discourse analysis of advertisements in english and vietnamese on the internet
... perspective of semiotics and discover the effects interpret the world around us of the combination of music, language and pictures in the success of Discourse analysis in advertising focus not ... Learning and pictures in advertisements Such discourse matters as lay-outs, 29 lexical choice and speech acts haven’t been discussed yet Besides, the instances used in this corpus were from online ... functions and the stylistic devices of advertisements in English and Vietnamese on the internet - To find out the effects of the combination of language, music and pictures in advertisements - To suggest...
- 15
- 2,309
- 3
A discourse analysis of advertisements in terms of persuasion strategies in english and vietnamese
... a lot of books in which discourse Analysis of Advertisements in terms of persuasion strategies in and discourse analysis are mentioned by well-known scholars such as English and Vietnamese” will ... languages In terms of advertisers (69.8% versus 58.3%) imperative sentences, EAs and VAs have the same using Imperative 5.2 IMPLICATIONS passive voice most in EAs is “Increase sentences are used in ... analysis of discourse analysis in terms of persuasion strategies in English and Secondly, basing on the typical discourse features of Vietnamese advertisements However, within the limitation of time...
- 13
- 1,084
- 2
A contrastive analysis of requests in english and vietnamese = so sánh lời đề nghị trong tiếng anh và tiếng việt luận văn tốt nghiệp đại học
... expressions, words and structures of requests in Vietnamese as well as English, then work out some affecting factors and politeness strategy of requests Besides, the frequency of using requests in ... with six sections They are forms of requests, request expressions, words and structures used in requests, the frequency of using requests in English and Vietnamese letters, factors affecting requests ... notion of politeness is often associated with indirectness It has been claimed that the degree of indirectness in requests is closely related to politeness So, what politeness is and its position in...
- 70
- 2,252
- 17
A contrative analysis of exclamation in english and vietnamese
... acts to commit themselves to future actions Promises and refusals are commissives - Expressives are those kinds of speech acts that state what the speaker feels They express psychological states ... anger, fear, disgust, happiness, surprise, and sadness Moreover, people every where express these feeling using the same distinctive facial gestures But people in various societies around the world ... Bless you! e Prasing someones performance Cheers! f Expressing annoyance You poor thing! g Expressing happiness at someones success Key: g 2f 3b 4e 5c 6a 7d II- Complete the sentences using exclamatory...
- 42
- 1,164
- 11
A discourse analysis of presuppositions in the declaration of independence made by president ho chi minh = phân tích diễn ngôn các tiền giả định trong tuyên ngôn độc lập của chủ tịch hồ chí minh
... Discourse Analysis 1.1.1 Discourse and Text There has been some confusion in using the two terms “discourse” and “text” Some researchers label their analysis “Discourse Analysis while others ... Allies…; possessives such as our workers, our forests, their sufferings and miseries…; and demonstratives such as this proposal, these last years The number of definite descriptions is too large ... items are just devices of assistance 3.2.1 In the Perspective of Semantics This section is hoped to present the findings about the different types of presupposition inducers used in the independence...
- 47
- 1,467
- 8
A contranstive analysis of consonants in english and vietnamese
... Minimal pairs: is pairs of words which are different in respect of only one sound segment The series of words pin, bin, tin, din, kin, gin, chin, fin, thin, sin, shin, win supplied with 12 words which ... example splice spy str sty skr sky Skw spring spew string stew screw skew Squirt 1.4.2 Final cluster A final consonant cluster is the cluster at the final position of a syllable The consonants that ... ŋk/ —»/ ŋks/ thing —» think—»thinks Clusters of four: /k/ —>/ks/ —>ksθ/ —»/ks s/ sicks—»six—»sixth—»sixths 43 Tips: Difficult final consonant clusters can be practiced using two words For example,...
- 54
- 938
- 5
An analysis of modality in some commentaries on global financial crisis 2008 2009
... Discourse Since discourse analysis is seen as a branch of linguistics, the term “discourse” has been defined in many different ways Discourse can be defined as a stretch of language consisting of several ... finish their discussion, teacher calls some representatives talking in front of the class Following are some suggestions topics for speaking class with modal expressions: - We are facing a serious ... emphasize This thesis just gives conclusion in small aspect of 33 some commentaries of Mr Rogoff Surprisingly, there is only one case that an adverb carrying modal meaning stands in the end of...
- 79
- 403
- 4
Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha thông tin liên lạc và các dịch vụ từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008