... primed with pEGFPIFIT4 or pEGFP-C1 were generated with days of GM-CSF/ IL-4 stimulation and further treatment with days of LPS, and then these DCLCs were cultured with allogeneic CD4+ cells with ... gene expression withdisease activity and lupus nephritis in patients withsystemic lupus erythematosus Arthritis Rheum 2006, 54:2951-2962 Crow MK: Interferon pathway activation in systemic lupus ... patients with SLE positively correlated with the presence of autoantibodies (ANA, anti-dsDNA and anti-Sm), leucocytopenia and hypocomplementaemia Compared with DC-like cells (DCLCs) primed with pEGFP-C1...
... [2] PAH is aggravated by physiological changes associatedwith pregnancy [3] Mortality in pregnant patients with PAH related to connective tissue disease is as high as 56% [4] Typically, patients ... first time cure of SLEassociated PAH and successful pregnancy with combination immunosuppressive and vasodilator therapy In healthy women, physiological changes associatedwith pregnancy and puerperium ... with inhaled iloprost was established to times daily at an initial daily dose of 50 mg, increasing to 100 mg within week A caesarean section was scheduled for week 37 Hemodynamic assessment with...
... iron absorption One possible underlying intestinal diseaseassociatedwith impaired iron absorption is celiac disease [3,4] Previously, celiac disease was usually considered in patients who had ... Furthermore, it is often associatedwith multiple deficiencies of macro- and micro-nutrients [3] It has only recently become clear that in addition to the classical form of celiac disease there is a ... count returned to the normal range without any specific treatment Discussion The clinical presentation of celiac disease is variable ranging from a "typical" form with diarrhea, steatorrhea, weight...
... Summary of results Alleles associatedwith patients CLU SLEIGH Caucasian (n = 62) AA (n = 135) Without Multiplex (n = 123) With Multiplex (n = 154) With Serositis none Without Nephritis none 239/241 ... of Fli1 and thus may be associatedwith lupus or with specific disease phenotypes such as nephritis The association of microsatellites with the occurrence of several diseases including SLE, rheumatoid ... initially hypothesized, specifically the possibility that a particular length may be associatedwithdisease or a disease phenotype Analyses of length in cases and controls in the CLU cohort were...
... closely associatedwith the MAPK pathway and 10 with cell signaling such as TCR and chemokine and cytokine pathways Unique pathways associatedwith non-progressive HIV disease Among the 15 MAPK -associated ... the patients, assisted with clinical follow up and details; WBD assisted with LTNP samples, intellectual input with LTNP biology, assistance with writing; YHY assisted with the mathematical and ... and CD8+ T cell transcriptomes from three different HIV disease groups was undertaken to identify gene expression signatures associatedwithdisease progression All the enriched categories derived...
... different disease durations and healthy controls Levels of bFGF were detectable in 4/9 patients with pre-SSc, in 2/9 patients with short disease duration and in 10/34 patients with longer disease ... (VEGF) in systemic sclerosis (SSc) patients with and without fingertip ulcers Compared with healthy controls, serum levels of VEGF were increased in patients with fingertip ulcers In patients without ... increased in patients with anti-topoisomerase antibodies and diffuse SSc, which are associatedwith a more rapid and severe disease course [38] These results are consistent with findings from Kikuchi...
... D-MEM/F12 supplemented with 10% FBS on a poly D lysine-coated 96 well plate at a density of 105 cells/well After 30 min, the medium was replaced with Neurobasal media supplemented with 2% B-27, 0.5 ... immunohistochemistry was performed as previously reported [21] with minor modifications Briefly, spinal cord tissue sections were treated with an antibody against Vgf (rabbit anti rat monoclonal D20, ... Cruz Biotechnology, Inc.) labeled with Zenon Alexa Fluor 594 (mouse IgG labeling kit; Molecular Probes Inc.) at 25°C for h Furthermore, the sections were treated with the monoclonal antibody against...
... condensation of dopamine (DA) with aldehydes or pyruvic acid Increased concentrations of these TIQs are found in the cerebrospinal fluid (CSF) of patients with Parkinson’s disease (PD) [1–3] Accumulation ... revealed that 6,7-dihydroxylated TIQs associatedwith PD FEBS Journal 275 (2008) 2109–2121 ª 2008 The Authors Journal compilation ª 2008 FEBS J Scholz et al compete with the essential tetrahydropterin ... with the essential pterin cofactor (Fig 2B); hTH inhibition by NMNorsal was noncompetitive with respect to tyrosine (data not shown) We compared the inhibitory effects of NMNorsal and NMSal with...
... of the association with religious attendance is about equal to that with family integrity An intact two-parent family and regular religious participation are also associatedwith the parent reporting ... structure and child behavior problems Children who live with both biological parents or two adoptive parents exhibit the fewest behavior problems Child Behavior Problems by Religious Attendance ... Survey of Children’s Health Finds Intact Family and Religious Participation Are Associatedwith Fewer Developmental Problems in SchoolAge Children By Nicholas Zill, Ph.D and Philip Fletcher, Ph.D.1...
... (solid line) and of patients with Alzheimer's disease Cumulative survival high (dashed line) initial AOC levels with Cumulative survival of patients with Alzheimer's diseasewith low (solid line) and ... levels being positively associatedwith cognitive performance: the median AOC value of the group with the lowest MMSE score range was significantly lower than that of the group with the highest MMSE ... AOC level as a factor significantly associatedwith survival of patients The hazard of dying was lower in patients with elevated AOC levels than in patients with low AOC levels (RH = 0.34; 95%...
... between systemic sclerosis and contraceptive use, earlier age of menarche, or ever being pregnant [9] A number of drugs have been reported to be associatedwith the development of scleroderma-like disease, ... who are more likely to have diffuse disease compared with Caucasians and Australians [8] Although hormones are supposed to play a role in the aetiology of the disease in women, a case control study ... between systemic sclerosis and exposure to solvents Since then several case reports and series [12-17] as well as epidemiologic studies [18-21] have found systemic sclerosis to be positively associated...
... Three plants with atypical CBD symptoms were also harvested in the states of Minas Gerais (MG) and MT Plants with atypical symptoms had all of the typical CBD symptoms along with withered and ... some states [2] The viral origin of CBD was only recently identified [3] In Brazil, the disease is associatedwith a virus from the family Luteoviridae, genus Polerovirus, named Cotton leafroll dwarf ... were observed with CLRDV, TYV, BMYV, BChV, and BWYV, respectively Phylogenetic analysis grouped the three divergent isolates with CLRDV in the Polerovirus branch of the tree, together with other...
... femur fracture associatedwith Paget's disease of the bone for which functional bracing was ultimately successful illustrates the usefulness of biological fracture treatment in patients with this ... fracture area Treatment of fractures secondary to Paget's disease using MIPO techniques might avoid the significant complications associatedwith more commonly used techniques of internal fixation ... middle thirds, and Paget's disease involving the entire femur of the fracture (Figure 5), the patient is able to walk unaided with a single T-cane Discussion Although Paget's disease of the bone is...
... Cell viability (%) A Without ascites With ascites * Without ascites With ascites * * * * * 10 TRAIL (ng/ml) 25 10 TRAIL (ng/ml) 25 Cell viability (%) 318A cells Without ascites With ascites * * 10 ... against TRAIL is associatedwith a shorter disease- free interval In previous studies, death receptors or ligands have been reported to be associatedwith outcome in patients with ovarian cancer ... activity of ascites against TRAIL is associatedwith a shorter disease- free interval in patients with ovarian cancer Journal of Ovarian Research 2010 3:1 Publish with Bio Med Central and every scientist...
... present late in disease course with widespread intra-abdominal metastasis Five-year relative survival rates drop from > 90% for disease diagnosed at an early stage to < 30% for disease diagnosed ... than controls No difference was identified between women with early stage disease and controls (p = 0.6) In addition women with late stage disease (p = × 10-4) and recurrence of their cancer (p ... levels seemed more indicative of disease status than CA125 Specifically, one of our 58 year old women with stage IIIC disease had a CA125 level of 32.3 U/ml (within normal limits) but a low GPX3...
... 16 teeth) had a higher risk for lung cancer (HR, 1.70) than men with 25 to 32 teeth Although periodontal disease was associatedwith significant increases in total (HR, 1.21) and hematological ... risk factors, including smoking and dietary factors, men with a history of periodontal disease had a higher risk for total cancer than men without such a history (HR, 1.14) When they looked at specific ... 541) Men who reported a history of periodontal disease at baseline had a slightly higher total cancer incidence than men without periodontal disease (unadjusted hazard ratio [HR], 1.28) After...
... Table Table Characteristics of patients with hepatocellular carcinoma (HCC) with chronic liver disease without cirrhosis or with CLD without cirrhosis treated with radiofrequency ablation (RFA) Characteristics ... in patients with hepatocellular carcinoma (HCC) associated to CLD without cirrhosis Fig Overall actuarial probability curves for new hepatocellular carcinoma associatedwith CLD without cirrhosis ... of RFA for HCC associatedwith CLD without cirrhosis, and current guide lines on this topic are limited Aim of this study was to investigate treatment with RFA for nodular HCC with no indications...
... patients with both SSc and PAH and from 26 patients with SSc without PAH who were randomly selected from among patients with SSc who donated DNA samples at the time of admission to Aoyama Hospital with ... significantly different between patients with SSc and PAH and healthy control individuals (P < 0.0001) and between patients with SSc with PAH and those with without PAH (P < 0.0001), as shown in ... the plasma of patients with SSc, especially in those with SSc complicated by PAH [13,14] However, reported levels of circulating NO in patients with SSc are inconsistent, with several studies [15-18]...
... arthritis patients with and without cardiovascular disease The baseline characteristics of the RA patients with and without CVD in our study population are shown in Table The RA patients with CVD were ... 0.001) Table Characteristics of rheumatoid arthritis patients with and without cardiovascular disease RA without CVD (n = 541) RA with CVD (n = 72) p value 62 (11) 67 (10)