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figure™1number of roh versus total length of rohs in each individual

Statistical methods for the detection and analyses of structural variants in the human genome

Statistical methods for the detection and analyses of structural variants in the human genome

Cao đẳng - Đại học

... identified an average of 207, 179 and 126 ROHs per individual for Chinese, Malays and Indians respectively Indians have lower numbers as well as lower total length of ROHs as compared to Chinese and Malays ... number of reads that fall in each pre-specified window of a certain size (Abyzov et al., 2011; Yoon et al., 2009) The underlying concept of identifying CNVs using DOC is similar is that of using intensity ... concepts in CNV /ROH analysis, including definitions and introduction to existing technology, software and algorithms in detection of CNV /ROH These will facilitate the understanding of subsequent...
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Báo cáo khoa học: Structure–activity relation for synthetic phenoxazone drugs Evidence for a direct correlation between DNA binding and pro-apoptotic activity pdf

Báo cáo khoa học: Structure–activity relation for synthetic phenoxazone drugs Evidence for a direct correlation between DNA binding and pro-apoptotic activity pdf

Báo cáo khoa học

... parameters of the endothermic melting of DNA and its complexes with drugs, calculated using eqns 2–4 and the binding parameters, DHbind, DSbind and DGbind, are summarized in Table Differences in interaction ... Synthesis of analogues of actinomycin XX Amides of actinocin containing crown ethers Zhurnal Organicheskoi Khimii 32, 406–408 17 Glibin, E.N., Ovchinnikov, D.V & Plekhanova, N.G (1997) Synthesis of ... stability (melting temperatures, Tm, and intervals of melting, DT) of DNA and its complexes are presented in Table A quantitative estimate of the binding parameters was obtained by subtracting the values...
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Báo cáo y học:

Báo cáo y học: "Direct electrochemical analyses of human cytochromes b5 with a mutated heme pocket showed a good correlation between their midpoint and half wave potentials" doc

Báo cáo khoa học

... heme-containing catalytic domain of about 99 amino acids; a membrane-binding hydrophobic domain containing about 30 amino acids at the carboxy terminus of the molecule; and a membranetargeting region ... acid in the presence of 200 μM of poly-L-lysine at 25°C as described in the main text Midpoint potentials were measured in the absence (line (a)) or presence (line (b)) of 200 μM of poly-L-lysine ... resulting in the independency on the polyL-lysine concentration However, our computer modeling study did not support any of these possibilities, indicating the limitation of this kind of modeling...
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báo cáo khoa học:

báo cáo khoa học: " A hypothetical correlation between hyaluronic acid gel and development of cutaneous metaplastic synovial cyst" potx

Báo cáo khoa học

... be interesting to consider the development of cutaneous metaplastic synovial cysts as a possible side effect of the use of hyaluronic acid fillers for increasing the volume of certain regions of ... cyst in the zygomatic region is the element of a seemingly obvious relationship: its formation was attrib- Figure Results of the histological examination of the cystic capsule utable to local injection ... Inchingolo et al Head & Face Medicine 2010, 6:13 http://www.head-face-med.com/content/6/1/13 Page of Figure Preoperative appearance of the neoplastic nodule ondary to injection of hyaluronic...
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Báo cáo y học:

Báo cáo y học: "Association between copy number variation of complement component C4 and Graves’ disease" ppsx

Báo cáo khoa học

... 5Division of Endocrinology and Metabolism, Department of Medicine, China Medical University Hospital, Taichung, Taiwan 6Department of Endocrinology and Metabolism, College of Chinese Medicine, China ... Taiwan 2Graduate Institute of Integrated Medicine, China Medical University, Taichung, Taiwan 3School of Chinese Medicine, China Medical University, Taichung, Taiwan 4Department of Health and Nutrition ... C4 polymorphisms according to the presence of GD is shown in Table No individuals had a full deficiency of C4 alleles After adjusting for age, individuals with copies of C4 gene were more susceptible...
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báo cáo khoa học:

báo cáo khoa học: " Ethical issues raised by common copy number variants and single nucleotide polymorphisms of certain and uncertain significance in general medical practice" potx

Báo cáo khoa học

... setting Our experience has been that findings of troublesome uncertain significance occur in about 1% of routine prenatal samples [23] Families seem not to be excessively distressed by findings of ... Competing interests The author is Professor and Chair of the Department of Molecular and Human Genetics at Baylor College of Medicine, which offers extensive genetic laboratory testing including ... many individuals and is illegal in many parts of the world For couples at in risk (such as when both carry a CF mutation) or in risk (such as an HNPCC mutation) of having an affected offspring,...
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A Contrastive Analysis between the Verb ‘Run’ in English and the Verb ‘Chạy’ in Vietnamese

A Contrastive Analysis between the Verb ‘Run’ in English and the Verb ‘Chạy’ in Vietnamese

Khoa học xã hội

... forms of ‘teacher’ and ‘teachers’ differ in respect of their grammatical meaning ‘Teacher’ is singular form (of a noun of a particular class), and ‘teachers’ is plural form (of a noun of a particular ... competitor • Running (noun): act of jogging or moving quickly; act of competing in a race or election, as in ‘Running in the early morning is my hobby’ 13 • Runnable (adjective): may be run, as in ‘The ... as to make something extent in space, as in ‘I need to run this wire along the wall.’ (9) To be operating/working Run, in term of the language of engineering or the language of information technology,...
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Tài liệu Báo cáo khoa học: The crystal structure of human a-amino-b-carboxymuconatee-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis ppt

Tài liệu Báo cáo khoa học: The crystal structure of human a-amino-b-carboxymuconatee-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis ppt

Báo cáo khoa học

... upregulation in the liver of streptozotocin-induced diabetic rats and the suppression of such elevation following insulin injection [21,22], we decided to investigate the effect of FEBS Journal ... represents the first structure of an ACMSD in a ligand-bound form and can be used to provide insights into catalysis In particular, the residues involved in inhibitor binding can be suggested to be ... Crystallization and structure determination Crystals of hACMSD were obtained using the vapour diffusion technique in hanging drop A volume of lL of reservoir solution containing mm DHAP, 2% poly(ethylene...
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Báo cáo khoa học: Interaction between Lim15/Dmc1 and the homologue of the large subunit of CAF-1 – a molecular link between recombination and chromatin assembly during meiosis pot

Báo cáo khoa học: Interaction between Lim15/Dmc1 and the homologue of the large subunit of CAF-1 – a molecular link between recombination and chromatin assembly during meiosis pot

Báo cáo khoa học

... the role of CAF-1 in chromatin assembly following various DNA synthesis events, its involvement in chromatin assembly following meiotic recombination is unknown In this study, we test the involvement ... Interaction between CcCac1L and CcLim15 in a yeast two-hybrid assay The inserts in the activation domain (AD) and DNA-binding domain (BK) are shown +, binding; ), no binding The mild selection medium (SD3: ... previously [44] The CcCac1L cDNA corresponding to 1146–2346 bp was used as a probe Immunostaining of nuclei of C cinerea meiotic cells Immunostaining of nuclei of C cinerea meiotic cells was performed...
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Báo cáo khoa học:

Báo cáo khoa học: "Augmented Dependency Grammer: A Simple Interface between the Grammer Rule and the Knowledge" pptx

Báo cáo khoa học

... clarified in any paper Suppose interpretalon is a process of determining the relation between " OBJECTs and THINGs ", the ordinary notion of semantics allows us to determine words' semantics in particular ... given in Fig Three different kinds of information sources other than the lexicon support language comprehension, and two inference functions defined on them extract the interpretation of input ... syntagmatic information, and further case interpretaion of subject-predicate,object-predicate relations However this kind of case interpretation brings into difficulties to select case marking ambiguities...
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Báo cáo khoa học: Correlation between conformational stability of the ternary enzyme–substrate complex and domain closure of 3-phosphoglycerate kinase potx

Báo cáo khoa học: Correlation between conformational stability of the ternary enzyme–substrate complex and domain closure of 3-phosphoglycerate kinase potx

Báo cáo khoa học

... units within a protein molecule Disruption of native PGK structure upon cooling occurs in two distinct stages, corresponding to independent and reversible unfolding of the individual domains [66,70–72] ... the individual PGK domains have been observed in the case of engineered mutants of yeast PGK that contain modifications in the hinge region between the two domains [20,68] and in the case of cold-active ... established interdomain interactions, resulting in a stronger coupling between domains Structural basis of PGK domain cooperativity: conserved features of the interdomain region In order to rationalize...
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HOW TO BRIDGE THE DISTANCE BETWEEN BUSINESS STRATEGY AND DESIGN.A VISUAL PRESENTATION BY MARTY potx

HOW TO BRIDGE THE DISTANCE BETWEEN BUSINESS STRATEGY AND DESIGN.A VISUAL PRESENTATION BY MARTY potx

Quản trị kinh doanh

... otherwise used for profit without the written permission of the author WHAT YOU’LL LEARN: A modern definition of brand The five disciplines of brand-building READY? LET’S START BY DISPELLING SOME MYTHS ... 1925 1950 Marketing today is about creating tribes 2000 People join different tribes for different activities DRIVING VOLKSWAGEN READING COMPUTING AMAZON DELL SPORTS COOKING BANKING NIKE WILLIAMS-SONOMA ... SOUTHWEST AIRLINES GOOGLE NISSAN UNITED ARTISTS HANES NORDSTROM VIRGIN Any brand can be charismatic EVEN YOURS But first, you have to master the FIVE DISCIPLINES OF BRAND-BUILDING DISCIPLINE 1: DIFFERENTIATE...
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Báo cáo khoa học: A dimer of the FeS cluster biosynthesis protein IscA from cyanobacteria binds a [2Fe2S] cluster between two protomers and transfers it to [2Fe2S] and [4Fe4S] apo proteins ppt

Báo cáo khoa học: A dimer of the FeS cluster biosynthesis protein IscA from cyanobacteria binds a [2Fe2S] cluster between two protomers and transfers it to [2Fe2S] and [4Fe4S] apo proteins ppt

Báo cáo khoa học

... results obtained with the variants containing single mutations this indicated that none of the three residues was involved in cluster binding In variants where one of the two cysteine residues in the ... number of proteins have been shown to be involved in the assembly of FeS clusters although the exact function of these proteins remained unclear In this work we studied the properties of the prominent ... ferredoxin (A) Apo ferredoxin was incubated with IscA1 carrying a FeS cluster After h an aliquot containing lg ferredoxin was removed and analysed by nondenaturing PAGE The gel was stained with Stains...
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Báo cáo khoa học: Insights into the design of a hybrid system between Anabaena ferredoxin-NADP+ reductase and bovine adrenodoxin pot

Báo cáo khoa học: Insights into the design of a hybrid system between Anabaena ferredoxin-NADP+ reductase and bovine adrenodoxin pot

Báo cáo khoa học

... synthesized In the present study we have tried to increase the knowledge of the parameters that keep running the ET reactions in proteins by the combination of two biological ET chains involved in the ... similarities, it is interesting to point out the different arrangement of the [2Fe)2S] centres of these Fds The cyanobacterial Fd presents an increased shielding from the solvent of the active Fe in ET when ... electrostatic interactions, which account for the initial protein–protein encounter, are rather weak, or that after breaking of the long-range interactions, short-range specific interactions at the protein–protein...
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báo cáo hóa học:

báo cáo hóa học: " Evaluation of adaptation to visually induced motion sickness based on the maximum cross-correlation between pulse transmission time and heart rate" docx

Hóa học - Dầu khí

... changes in ρmax of individual subjects from Day to Day Each value represents ρmax at Part-3 As shown in this figure, the ρmax increased for of subjects in TS-down group and for of subjects in TS-up ... Journal of NeuroEngineering and Rehabilitation 2007, 4:35 Background In recent years, medical services including rehabilitation programs are changing substantially as results of rapid aging of the ... coefficient is defined as physiological index: Figure subjects from Day to Day 3, in SSQ total score (TS) of 14 Change,2 Change, from Day to Day 3, in SSQ total score (TS) of 14 subjects Page of (page...
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Báo cáo hóa học:

Báo cáo hóa học: " The correlation between radiative surface defect states and high color rendering index from ZnO nanotubes" docx

Hóa học - Dầu khí

... reason of the strong emission of the UV could be assigned to the entrance of the electron beam into the nanotube where it can travel adopting a helical path by striking again and again with the inner ... Color rendering index, color temperature, R9 and x, y coordinates values corresponding to different injection currents Color temperature Color rendering index R9 X-coordinate Y-coordinate 50 4,586 ... Science and Technology, Campus Norrköping, Linköping University, SE-601 74 Norrköping, Sweden 2School of Materials Science and Engineering, Georgia Institute of Technology, Atlanta, GA 30332-0245...
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Báo cáo sinh học:

Báo cáo sinh học: "A balancing act between the X chromosome and the autosomes" ppsx

Báo cáo khoa học

... These findings confirm that, in Drosophila somatic tissues, there is a doubling of transcription from the single male X chromosome In the germline, however, the findings of Gupta et al [8] suggest ... hypertranscription of the male X chromosome in the Drosophila soma may be related to the use of common pathways between sex determination and dosage compensation in this species Interestingly, the expression of ... chromosomes in females (pink) and the single X chromosome in males (blue) is also equal to 1.0 To achieve this dosage compensation, the single X chromosome in the Drosophila male soma and germline,...
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Báo cáo y học:

Báo cáo y học: " A rigid barrier between the heart and sternum protects the heart and lungs against rupture during negative pressure wound therapy" doc

Báo cáo khoa học

... was inserted Anesthesia was maintained with a continuous infusion of ketamine (Ketaminol® vet 50 mg/ml; 0.4-0.6 mg/kg/h) Complete neuromuscular blockade was achieved by continuous infusion of ... importance of protecting exposed organs during NPWT has received increasing attention recently, following reports of heart rupture and death Sartipy et al described cases of injury following NPWT of ... deep sternal wound infection in Sweden, of which were fatal [7] In a series of 21 deep sternal wound infections treated with NPWT, Bapat et al reported that one of a total of mortalities was...
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Báo cáo y học:

Báo cáo y học: "a diagnostic dilemma between psychosis and post-traumatic stress disorder: a case report and review of the literature" ppsx

Báo cáo khoa học

... the emergence of psychotic features in a preceding PTSD Some authors underline the importance of both disorders being characterized by intrusions In PTSD, the interpretation of intrusive symptoms ... style culminates in feelings of shame, guilt and worthlessness, which emerge during trauma acting as positive feedback to enhance symptom severity and keep the individual in a constant state of psychotic ... was made to integrate all aspects relating to his history in a meaningful way [3] In our case report, our patient had PTSD symptoms including experiencing recurrent distressing images of the traumatic...
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