... variation is not situated within a conserved sequence; therefore, it might not have a functional consequence on the regulation of transcription of MMP2 Even though the functional potential of this ... showing low Clark level lesions It is of note that we are unable to verify whether the missingness of data on TILs in this study is informative therefore these results should be considered preliminary ... to the one reported in the dbSNP forthe Italian panel, but the inverse distribution was seen when compared to the PGA-European panel Although this difference was not significant (p = 0.73) The...
... markers of response to therapy and thus be related to outcome Therefore, we investigated whether baseline status or levels of ACPA or IgM-RF and their changes in the year thereafter are associated with ... over the first year occurred in the majority of patients, with a median decrease in level of 22% for ACPA and 28% for RF Recently, another study in very early RA patients reported an increase of ... represent the change in the Disease Activity Score on 28 joints (DAS28) in the first year The Y-axes of c and d represent the change in the Health Assessment Score (HAQ) in the first year The Y-axes of...
... S The male flowers (catkins) Theperiodof male flowering extends from the end of March to the end of July (the anthers are dehiscent and the majority of pollen from a single tree is shed) The ... development periods coincide withthe end ofthe unfavorable season, in these trees, annual flowering coincides withthe fertilization ofthe flowers ofthe previous year In Umbria de Valcorchero the ... the beginning ofthe development ofthe young prolonged acorn summer will coincide withthe drought To avoid this, the species has resorted to an extension oftheperiodof dormancy so that the...
... approved the final manuscript Acknowledgements We thank our research nurses and the nurses of our ICUs for their help withthe collection ofthe blood and urine samples PP is a recipient of a Clinical ... Clinical Fellowship grant ofthe Netherlands Organisation for Scientific Research (ZonMw) References The SIG – indicative ofthe presence of unmeasured anions, which are often present in metabolic ... MM collected all ofthe data and drafted the manuscript PP conceived the study and cowrote the manuscript PvdV and JGvdH participated in the design ofthe study and corrected the manuscript All...
... processing ofthe CA-SP1 junction in the SIVm3 virions was only moderately affected by DSB as compared to the more pronounced effects ofthe compound on cleavage of HIV-1 Page of 10 (page number notfor ... shown are normalized against the infectivity ofthe respective vehicle-treated virus The absolute infectivity values ofthe control viruses are shown in Fig 2B Results are representative of two ... assayed for infection of P4-CCR5 indicator cells Infectivity was calculated after normalizing forthe RT content ofthe SIV inocula Values shown are normalized against the infectivity ofthe vehicle-treated...
... fraction ofthe children in group NA reported heredity for these diseases Figure shows the number of registered health care visits with a diagnosis of asthma from birth up to the age of seven forthe ... investigations ofthe maternal medical records at the University Hospital, including PHC data ofthe statements made by the mid-wife in her records ofthe check-up ofthe mothers during the pregnancy ... included in the study At the age of seven, all of them still living in the region were included in a follow-up of their computerised medical records, which were examined forthe occurrence ofthe diagnosis...
... sceptical view about the existence of normative reasons, rather than an internalist theory of them Then another large part of what Hume says is concerned withthe psychological question of what gives ... moreover, his reasonsfor excluding prudential and moral considerations, unless they are already in the agent’s S, not turn at all on whether these considerations are or arenot a priori They turn ... truth-condition for them in the form of (I) He then challenges the external reasons theorist to explain the content of propositions about reasons in a way which shows how external reasons can exist:...
... it’s not right that those who promise to pay you for a job arethe ones who ask for money before giving you the promised job More often than not, those who ask for any fees up front are scams They ... read the Privacy Policy to make sure that the site is legitimate If the site has no prominent Privacy Policy link, then ignore it and look for another survey site 2 There are scammers out there ... not ask for membership fee or other recurring fees Scammers are getting clever these days, so don’t be fooled The job or the site may appear legitimate, with all the photos and testimonials of...
... Newsletter Why hormones arenot used: There are a number ofreasonswhy hormones arenot used in the poultry industry In the United States, European Economic Community, and most other developed ... productive The hormones which may enhance growth are actually proteins Therefore, if they were consumed in the feed they would be digested in the same way as the corn or soybean meal that they eat The ... what the levels of protein, energy, vitamins and minerals are to achieve optimal growth and performance Third, is the understanding ofthe environmental needs ofthe birds The healthier the environment...
... distinguish the fact that they are performers and that is what they for a living; instead they copy what they see Another, group that had a great influence on girls is the Spice Girls The group of five ... also punish themselves fornot having perfect bodies They believe, "It is our body's fault that we arenot happy- with our relationships, our jobs, and our lives." Therefore, they deny their bodies ... women" There message was truly positive to young girls everywhere, however the message some how did not fit with their image Their attitude and appearance were just one of many reasonswhy their...
... comprised ofthe program coordinator and supervisors, the principal ofthe school, and the research team The role of each organization is different but each provides information and support forthe other ... Savings Accountsfor College ICS accountsare held in a bank as savings accounts in the child’s name, but under the custodial care of and monitored by the implementing agency Statements are sent ... longitudinal research The paper begins withthe design features ofthe school savings program Next, we examine patterns of deposits, saving, and withdrawals during the first two years ofthe program Although...
... indicated WT denotes untransfected HEK293 cells The positions of molecular mass markers (in kDa) are indicated to the left ofthe blot and the position of SUR1 is indicated by the arrow Note that ... deletion ofthe C-terminus of SUR1 affects the efficacy of drug response To further characterize this, dose–response curves were constructed for two of these and it was found that the Ki was not significantly ... rise to currents significantly in excess ofthose from wildtype cells [15] However the magnitude of these varied with clonal isolates and some lines possessed smaller currents than others With 1.2...
... Source: WHY HAVE ENTERPRISE SOFTWARE VENDORS #FAILED WITH USER EXPERIENCE? THE BUYER & THE USER ARENOTTHE SAME PERSON ENTERPRISE SOFTWARE USERS ARE A CAPTIVE AUDIENCE ENTERPRISE SOFTWARE IS RARELY ... considerations in the workplace.” out of 10 people recalled the last time they saw a product they just had to have, and it was because ofthe design ofthe product IEEE STUDY $1,000,000,000 THE AMOUNT ... CONSUMER SOFTWARE ENTERPRISE SOFTWARE DEVELOPMENT IS LARGELY TECHNOLOGY & FEATURE FOCUSED BIG IDEAS THE USER EXPERIENCE OFTHE SOFTWARE THAT RUNS YOUR BUSINESS IS AS IMPORTANT AS ANY OTHER MAJOR...
... particular have led to the rise of global transparency: the spread of democratic governments, the rise ofthe global media, the spread of nongovernmental organizations, the proliferation of international ... some ofthe worst offenders Moreover, disclosure regimes exist in only a small number of issue areas and, even in those areas the high costs of collecting and reporting information limit their ... abuses of state power around the world International organizations monitor the behavior of governments and determine whether they are adhering to international agreements Together, these forces are...
... expression data was performed withthe LightCycler software (version 3) Crossing points were assessed by the second derivate maximum algorithm and plotted against the concentrations ofthe standards Sample ... analyzed using CellQuest software Results and Discussion Ten HLA-A2 positive patients with AML were analysed for mRNA expression levels of WT1 and for mutations ofthe WT1 epitope or epitope ... loss ofthe HLA-A2 allele, we analyzed HLA-A2 expression on leukemic blasts of patients In all patients more than 90% of blasts stained positive for HLA-A2 In none ofthe patients a difference of...
... ending, the former is usually given withthe word and the other is added: e g., aequilate -us, instead of aequilatus, there being no difference in the application Usually the singular form ofthe ... pair of membranous scales above the halteres, behind the root ofthe wing, one above or before the other; the anterior attached to the wing and moving with it, the posterior fastened to the thorax ... whose definitions are used, or who have used the term in the sense defined In the terms of venation, these parentheses occur most frequently Most ofthe signs and abbreviations arethose in common...
... cooperating withthe negotiations at the 1997 Kyoto Round (the Third Session ofthe Conference ofthe Parties) and the 2000 Hague Round (the Sixth Session ofthe Conference ofthe Parties) ofthe United ... study ofthe development ofthe American federal government, has noted that the rise ofthe natural resource management agencies and ofthe regulatory apparatus that went along with them was one of ... the rise ofthe environmental regulatory state to be one ofthe central and defining features ofthe development ofthe modern form of liberal democratic government in the Western countries There...
... species The evolution of life must be at least part oftheexplanationofthe development and forms of consciousness The problem, then, is this: What kind ofexplanationofthe development of these ... the laws of physics, or the existence and properties of God and therefore of his creation, cannot conceivably be other than they are Physicists not typically believe the former, but theists tend ... part ofthe larger project of making sense ofthe world Further, any such explanation must account forthe fact that the appearance of consciousness on earth and the different forms it takes are...
... the year ofthe mobile web 2007: the year ofthe mobile web 2008: the year ofthe mobile web 2009: the year ofthe mobile web 2010: the year ofthe mobile web lim 2005: the year ofthe mobile ... hardware 2006: the year ofthe mobile web small ma 2007: the year ofthe mobile webrket bad browsers 2008: the year ofthe mobile web costly data 2009: the year ofthe mobile web ns pla 2010: the ... the year ofthe mobile web 2010 WAS THE YEAR OFTHE MOBILE WEB 2011 WILL BE EVEN MORE SO BATTLE OFTHE DEVICES By chriswsonic357 on Flickr JANUARY 2007 APPLE IPHONE The iPhone has taken the frustration...
... hospitals accounted for 11.8% of admissions, and 2.3% of admissions were identified as being readmissions ofthe same patient within the same hospital stay Compared withthosenot mechanically ventilated ... of onset of asthma or amount of maintenance therapy), management, ventilation strategies, complications and detailed evolution ofthe condition within the ICU stay arenot collected as part of ... described for all admissions with asthma, admissions of patients with asthma who were mechanically ventilated during the first 24 hours and those who were notThose aged less than 16 years and those...