... reliability between observers and was 0.86 Fig Unilateral absence ofthefrontal sinus; on the right, the absence ofthefrontal sinus, and on the left, the limited aeration ofthefrontal sinus; axial ... may expand and cross the midline toward the agenetic side, which mimics the presence of bilateral frontalsinuses [1] CT scans of agenetic patients show almost normal frontal recesses and sinuses, ... a metopic suture, thefrontalsinuses are small or absent [8-10] The form ofthe face and forehead in the presence of a metopic suture conforms to the evolutionary trend ofthe skull [30] In...
... specialty, address, and place of work These reports are tallied and published as the Survey of Physicians [13] The number of medical doctors in our baseline year of 2008, stratified by sex and age, was ... in a serious doctor surplus in Japan The purpose of this study is to project the future growthofthe Japanese medical workforce and to forecast whether the 80 000 65 + 15 - 64 60 000 - 14 40 ... especially after most ofthe baby boomers die Yet the Japanese government andthe two major parties have given little thought to predicting long-term trends in the supply ofand demand for medical...
... those ofthe bailiff: he looked after all the live and dead stock ofthe manor, saw to the manuring ofthe land, kept a tally ofthe day's work, had charge ofthe granary, and delivered therefrom ... freeholders; andthe territory is divided into demesne land and tributary land of two classes, viz that ofthe villeins and that ofthe freeholders The cultivation ofthe demesne (which usually means the ... meadow, andthe corn on their strips of tillage, both grass and stubble became common land and were thrown open for the whole community to turn their stock upon The size ofthe strips of land in the...
... at the wood level The spacing of parenchyma bands, the radial enlargment of wood fibres and parenchyma cells, the wall thickness of wood fibres and to a lesser extent the width of parenchyma bands, ... segments, and these were measured In addition, the number of tiers per unit, the number of branches per tier, the number of sympodial units per branch, the mean basal diameter of branches andthe circumference ... 5A) These variations resulted mainly from changes in the number of cells per unit area (fig 5B) These types of concentric and repeated variations - in the spacing of parenchyma bands and in the...
... examine the temporal aspects ofthegrowthof young Terminalia superba trees in the same natural environment, including the lateral and radial growthofthe tree In the present paper, shoot growthof ... hairs) At the resumption of shoot growth, a few leaves arrested in their growth fell off and short internodes were then found on main stems, indicating a period ofgrowth rest For the rest ofthe observation ... activi- ty ofthe main apex and to the appearance of sylleptic outgrowths nearby, on the main shoot in general These concomitant (maximum activity ofthe main apex andthe appearance of sylleptic...
... biomolecules into and out ofthe cell, and, regulate the production of themselves or other proteins In order to accomplish these functions, proteins often works together with another protein or ... process within and between the cell(s), the cascade of immune responses, the process underlying cell adhesion andthe regulation ofthe cell cycle are but a few 16 ofthe essential tasks of proteins ... sequence) The process is known as the transcription of DNA The mRNA transcripts are then exported out ofthe nucleus into the cytoplasm for protein production This process, called the translation of the...
... different proof ofthegrowthofthe number of simple closed geodesics by using the ergodic properties ofthe earthquake flow on PMg,n , the bundle of measured geodesic laminations of unit length ... Similar upper and lower bounds for the number of pants decompositions of length ≤ L on a hyperbolic surface X were obtained by M Rees in [Rs] Idea ofthe proof of Theorem 1.2 The crux ofthe matter ... of cX (L) is independent ofthe genus of X See [Bus] andthe references within for more details and related results Similar statements hold for thegrowthofthe number of closed geodesics on negatively...
... ) < exp(Cn1+δ ) The strategy for the proof of this theorem is the same as the strategy ofthe proof of Theorem 1.3.9 described in Chapter Denote the supremum C and C -norms ofthe family (3.1) ... to the strategy ofthe proof of Theorem 1.3.9 At the n-th stage ofthe induction over the period we consider the family of polynomial ˜ perturbations {fε
... complex of E coli [22], the 5¢-end ofthe bound DNA molecule was not in the vicinity ofthe DNA-binding pocket of RecD Therefore, it is not clear how the invariant D and E residues ofthe ATP-binding ... RecD The 5¢-end ofthe DNA substrate has also been shown schematically to indicate the relative positions of domains andof RecD as seen in the structure ofthe DNA-bound RecBCD complex of E ... between the wild-type and mutated amino acids The location ofthe H386D mutation between motifs III and IV is also indicated (B) Alignment ofthe amino acids ofthe seven helicase motifs of RecD...
... component of LM(L(G)) Proof The first part ofthe corollary follows from Lemma 12, andthe second part follows from Lemmas 15 and 16 Corollary 18 There exists an integer J1 such that every component of ... a component of LMk+1 for k ≥ J1 , and every component of LMk+1 is generated by exactly one component of LMk Proof Let ck denote the number of components of LMk By Corollary 17, the sequence ... characterization of graphs for which the MDGP holds Lemma The MDGP holds for a graph G if and only if L(M(G)) ∼ M(L(G)) = Proof Assume that the MDGP holds for G Then M(G) has an edge, and by Lemma...
... COMPENSATORY GROWTHOFTHE SANDBAR SHARK but they were unable to rule out their methodology as the cause of these differences Cassoff et al (2007) reported changes in life history parameters ofthe Porbeagle ... MSE and AIC values, the VB3 model provided the best fit for males and females for the VIMS1983 data set COMPENSATORY GROWTHOFTHE SANDBAR SHARK 193 FIGURE Length frequencies of (A) female and ... in the parameters ofthegrowth model for Sandbar Sharks in the WNA between the periods 1980–1983 and 2000–2004 that indicate slightly faster growth We also have found a decrease in the value of...
... ofbone graft in the damaged site and on the other hand, it creates an environment with a rich content of HA, with all the advantages deriving from the phenomenon The present study’s clinic and ... showed absence ofbone remodelling, and satisfactory filling ofthe infra -bone defects with the graft material in situ After months, radiographs showed presence of mild bone remodelling and excellent ... proliferation, migration, and differentiation ofthe epithelial cells [2,12,18,19] Following the surgical treatment of adult periodontitis, the epithelial regeneration ofthe periodontal attachment...
... cloned into pGEX-4T-2 The KIND domains of Spir-2 and PTPN13 were generated by RT-PCR and inserted into pEGFP-C1 and pGEX-4T-2 The N- and C-terminal regions ofthe v-KIND KIND2 andthe MAP2 CD were ... structural and functional importance ofthe v-KIND and MAP2 interaction core modules in the regulation of dendrite growthand branching in hippocampal neurons and cerebellar granule cells Further studies ... proteins of these subregions (Fig S1C) and 1654 Fig Of all members ofthe KIND family of proteins, only KIND2 binds to MAP2 Pull-down assay (PD) ofthe endogenous MAP2 from cerebellar lysates of P21...
... the greatest blood supply These include the ends ofthe arms and legs (nearest the torso), the pelvis, the ribs, andthe spine When lung cancer spreads to bone, several factors can increase the ... called growth factors that promote thegrowthofthe cancer cells, creating a vicious cycle in which: ― Growth factors are released as bone is destroyed ― Thegrowth factors stimulate thegrowthof ... remodeling During thebone remodeling process: • Bone cells called osteoclasts break down and remove (resorb) bone • Bone cells called osteoblasts make and deposit new bone at the site ofbone removal...
... subfamily ofthe Bcl-2 family involved in the initiation of apoptosis through the mitochondrial pathway The key event in the mitochondrial pathway is the release of proapoptotic factors from the mitochondrial ... apoptosis The mitochondrial release of cytochrome c and second mitochondria-derived activator of caspase (Smac ⁄ DIABLO) allows for the formation ofthe apoptosome, a complex that enables the activation ... there could be a link between EGF-induced reduction in Bid and tBid levels andthe ubiquitin ligase activity of Itch In this study, we first examined the ability of Itch to interact with Bid and...
... neurodegenerative disease Synthesis and secretion of GIF in the brain Cellular and temporal localization of GIF synthesis Whilst the MT1 and MT2 isoforms are ubiquitously synthesized throughout most ... conditions [22] In the traumatically injured brain, however, the synthesis of MT1 and MT2, as well as the synthesis of GIF, are up-regulated by reactive astrocytes in the vicinity ofthe lesion [23] ... remains no clear consensus on the role of GIF in the pathogenesis of AD, and therefore we will briefly review some ofthe current thoughts on the role of GIF in AD There are numerous pathological...
... a candidate target of miR-23a miR-23a expression level 20 growth activities at the same time points (Fig 2A) To detect the effect of miR-23a on the long-term and independent growth activity of ... and colony formation assays confirmed the active role of miR-23a in thegrowth promotion of malignant cells The fundamental function of miRNAs is to regulate their targets by direct cleavage of ... ofthe tumor types were confirmed by pathologic analysis The experiments were undertaken with the understanding and written consent of each subject The study methodologies conformed to the standards...
... removal ofthe CUB domains and thereby activation ofthegrowth factor domains PDGF-C and -D contain both the CUB andgrowth factor domains when they are secreted and proteolytic cleavage is therefore ... and -D, structure and function L J Reigstad et al endothelial growth factors (VEGF) andthe family is therefore often referred to as the PDGF ⁄ VEGF family The PDGF family ofgrowth factors The ... lymphoid cell infiltrates ofthe lung and fibrosis in the liver [110] Conclusions The novel members, PDGF-C and -D, ofthe PDGF subfamily ofthe cystine knot family ofgrowth factors are potent...
... discussion ofthe thermotropic phase behavior of Myr2Gro-PGro and other members ofthe homologous series of linear saturated PGs, see Zhang et al [24] The addition of mol percent of one ofthe three ... decreases in the order GS14 > GS10 > GS12, as does the temperature andthe relative magnitude ofthe new endotherm or endotherms induced by the addition ofthe peptide However, the magnitude ofthe effects ... conformation There is good evidence from studies ofthe interaction of GS and its analogs with bacterial cells that the destruction ofthe integrity ofthe lipid bilayer ofthe inner membrane is the primary...
... quanti®cation The DNA content ofthe cell layer at the end of incubation was quanti®ed by the method of West et al [31] After solubilization ofthe cell layer in M NaOH and subsequent neutralization ... probe and calf thymus as standard 365 488 289 665 Direct implication of cAMP increase, the second messenger of FSH, in the bFGF regulation was evaluated by addition to the culture medium of either ... testicular development, the physiology of Sertoli cells is modi®ed The cell proliferation decreases and ceases allowing the establishment ofthe hematotesticular barrier around the 20th day postpartum...