endoscopic head and neck surgery the impact of minimally invasive surgery within multidisciplinary care
Báo cáo khoa học: "Prognostic factors for lymph node metastasis from advanced squamous cell carcinoma of the skin of the trunk and extremities" doc
... the parotid gland Head Neck 2001, 23:744-748 Joseph MG, Zulueta WP, Kennedy PJ: Squamous Cell Carcinoma of the skin of the trunk and limbs: The incidence of metastases and their outcome Aust ... development of lymph node metastasis, the presence of scar or ulcers previously in the area of the tumor This was observed also in other studies [10,18] The association of UV damage and a burn ... most of them are heterogeneous or include also initial stage lesions and head and neck tumors [1016] The present study investigates a consecutive series of only localized advanced SCCS of the...
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Báo cáo khoa học: "Normalization of prostate specific antigen in patients treated with intensity modulated radiotherapy for clinically localized prostate cancer" pot
... obtained the retrospective data from the charts, and wrote the first draft of the paper GDAP and PC conceived of the study, and participated in its design and coordination and helped to draft the ... relationship between the rate of normalization of PSA and the duration of NAAD therapy Previous studies have attempted to determine the optimal duration of androgen deprivation therapy for men with ... when the level of PSA normalization was set at less than ng/mL It is possible that the use of NAAD therapy acts as a radiosensitizer in areas of the tumor mass It is also possible that the androgen...
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Báo cáo khoa học: "Prior surgical intervention and tumor size impact clinical outcome after precision radiotherapy for the treatment of optic nerve sheath meningiomas (ONSM)" docx
... complained of new headaches, and three of recurrent hyperlacrimation of the irradiated eye, one with change of taste perception None of the patients developed dysfunctions of the pituitary gland, neuropathy, ... Sabine Kuhn and her team of technicians for excellent patient care Authors’ contributions SC, JD and SR treated the patients SA, SR and SC collected the data SC and SA evaluated the dataset and performed ... analysis SC, SA, SR, TW Page of and JD wrote and edited the manuscript All authors read and approved the manuscript Conflict of interest The authors declare that they have no competing interests...
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Báo cáo y học: "Genome-wide identification of novel expression signatures reveal distinct patterns and prevalence of binding motifs for p53, nuclear factor-κB and other signal transcription factors in head and neck squamous cell carcinoma" docx
... Determination of the regulation of these genes will require further study of the potentially complex contribution of expression, phosphorylation, and co-factor interaction of wild-type and p53 mutants, and ... J, Bradford C, Carey T, et al.: Genetic and expression profiles of squamous cell carcinoma of the head and neck correlate with cisplatin sensitivity and resistance in cell lines and patients Clin ... relationship between expression of cluster A and B genes and their association with dominant prevalence of binding sites of p53 in cluster A genes, and NF-κB, AP-1, and other transcription factors...
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Báo cáo khoa học: Alternative splicing produces an H-protein with better substrate properties for the P-protein of glycine decarboxylase doc
... extension of four amino acid residues at the N-terminus of each recombinant protein after removal of the His tag (Fig S4) The kinetic differences between the normal and alternative H-proteins, either ... and the artificial AtGLDH1AA, are indeed exclusively due to the insertion of two additional alanyl residues into the N-terminus of the H-protein In conclusion, the substrate properties of the ... is present at levels of approximately mm in the matrix of pea leaf mitochondria, which is 7-fold higher than the concentration of P-protein [12] and 40-fold higher then the Km values determined...
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Báo cáo sinh học: "High ERCC1 expression predicts cisplatin-based chemotherapy resistance and poor outcome in unresectable squamous cell carcinoma of head and neck in a betel-chewing area" pdf
... from the date of start of chemotherapy to the date of death or most recent follow-up Progression free The median age of the patients was 53 years (range 3672 years), and fifty-five (96.5%) out of ... (creatinine clearance >60 ml/min), and a computed tomography or magnetic resonance image scan of the head and neck region within three weeks prior to the initiation of treatment The clinicopathological ... cisplatin is the backbone of the chemotherapy regimen as a component of IC and CCRT in the treatment of locally advanced HNSCC Its main cytotoxic activity is based on the formation of DNA adducts,...
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AUDIT TOGETHER WITH INDEPENDENT AUDITORS* REPORT FOR THE PERIOD JULY potx
... amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements and the reported amounts of revenues and expenses during the reporting ... amounts of assets and liabilities and disclosures of contingent assets and liabilities at the date of the financial statements and the reported amounts of revenues and. expenses during the reporting ... Board of Regents policy and allows the Foundation to manage funds on behalf of the University The Foundation is a separate legal entity and not included as part of the reporting entity of the University...
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Báo cáo sinh học: "Membranous expression of Her3 is associated with a decreased survival in head and neck squamous cell carcinoma" pot
... value of c-erbB2 and other markers in patients treated with chemotherapy for recurrent head and neck cancer Head Neck 2000, 22:599-608 33 Werkmeister R, Brandt B, Joos U: Clinical relevance of erbB-1 ... contributions J-YC and SMH conceived of the study and devised the experimental design SMH and CM designed and build the tissuemicroarrays MT, J-YC, and YK performed experiments RX, HC, J-YC and SMH performed ... Collection of the material and TMA construction was supported by The University of Virginia School of Medicine through fellowship support of Seung-Mo Hong who collected cases and provided the design...
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báo cáo hóa học:" High ERCC1 expression predicts cisplatin-based chemotherapy resistance and poor outcome in unresectable squamous cell carcinoma of head and neck in a betel-chewing area" pdf
... from the date of start of chemotherapy to the date of death or most recent follow-up Progression free The median age of the patients was 53 years (range 3672 years), and fifty-five (96.5%) out of ... (creatinine clearance >60 ml/min), and a computed tomography or magnetic resonance image scan of the head and neck region within three weeks prior to the initiation of treatment The clinicopathological ... cisplatin is the backbone of the chemotherapy regimen as a component of IC and CCRT in the treatment of locally advanced HNSCC Its main cytotoxic activity is based on the formation of DNA adducts,...
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báo cáo hóa học:" Membranous expression of Her3 is associated with a decreased survival in head and neck squamous cell carcinoma" doc
... value of c-erbB2 and other markers in patients treated with chemotherapy for recurrent head and neck cancer Head Neck 2000, 22:599-608 33 Werkmeister R, Brandt B, Joos U: Clinical relevance of erbB-1 ... contributions J-YC and SMH conceived of the study and devised the experimental design SMH and CM designed and build the tissuemicroarrays MT, J-YC, and YK performed experiments RX, HC, J-YC and SMH performed ... Collection of the material and TMA construction was supported by The University of Virginia School of Medicine through fellowship support of Seung-Mo Hong who collected cases and provided the design...
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Báo cáo hóa học: " Unscented Kalman filter with parameter identifiability analysis for the estimation of multiple parameters in kinetic models" pptx
... sensitivity to the system output and then which of the parameters are linearly independent The method iterates over the columns of the sensitivity matrix Z to select the column with the highest sum of squared ... based on the model structure and the measurement data One of the benefits in integrating estimation and identifiability is the reuse of the variance generated by the UKF for the step size in the calculation ... sensitivity To make the adjustment of the net influence of each of the remaining parameters on the already selected parameters, all of the original columns of Z are being regressed on the column associated...
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Báo cáo hóa học: " A New MAC Protocol with Pseudo-TDMA Behavior for Supporting Quality of Service in 802.11 Wireless LANs" docx
... by the packet accumulation The second part is the expected value of a uniform random variable of how long a priority call may wait in states and Expected delay is independent of the load of the ... calculate the behavior of the proposed model in comparison with EDCA The performance of the MAC protocols is tested for variable number of contending stations, basic and handshaking access, and the ... Kingdom, and he is an M.Phil and Ph.D holder since 1978 and 1985, respectively Currently he is a Member of the academic staff of the Department of Electrical and Computer Engineering of the University...
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Báo cáo hóa học: " ITERATIVE SCHEMES WITH SOME CONTROL CONDITIONS FOR A FAMILY OF FINITE NONEXPANSIVE MAPPINGS IN BANACH SPACES" docx
... et al 127 In general, the control conditions (1.6) and (1.7) are not comparable (coupled with conditions (1.2) and (1.3)), that is, neither of them implies the others as in the following examples ... (1.2), (1.3), and (1.8) Then the iterative sequence {xn } defined by (1.1) converges strongly to QF a, where Q is a sunny nonexpansive retraction of C onto F Proof As in the proof of [1, Theorem 1], ... nonempty closed convex subset of a smooth Banach space E, let D be a subset of C, let J : E → E∗ be the duality mapping of E, and let Q : C → D be a retraction Then the following are equivalent:...
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báo cáo khoa học: "Sentinel lymph node biopsy for high-risk cutaneous squamous cell carcinoma: clinical experience and review of literature" ppsx
... upon the need for close surveillance regardless of the SLN status This study and review of literature highlights the potential limitations of SLN biopsy for SCC and the critical importance of careful ... collection and data analysis, reviewed the literature, and wrote the manuscript ZD provided the pathology figures and legends PW wrote the manuscript and supervised the work All authors read and approved ... Acknowledgements The authors wish to thank Drs Noel Weiss and Thomas Lumley for their helpful review of the epidemiological and analytical methods Author details Department of Surgery, University of Washington,...
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Báo cáo khoa học: "Large volume unresectable locally advanced nonsmall cell lung cancer: acute toxicity and initial outcome results with rapid arc" potx
... received by the x% of the volume; Vx% = volume receiving at least x% of the prescribed dose; CI = ratio between the patient volume receiving at least 95% of the prescribed dose and the volume of the ... RA with the aim of paving the way for further study of dose escalation In the present study, acute toxicities and initial outcome results, were evaluated and reported Methods Patients and procedures ... margin of mm from the primary tumor and of mm from the involved regional lymph nodes The protocol of treatment started with patients presenting stage III lung cancer in the upper quadrant, and with...
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Báo cáo khoa học: "Recurrence patterns of locally advanced head and neck squamous cell carcinoma after 3D conformal (chemo)-radiotherapy" pdf
... years and Definition of failure site Each local or regional treatment failure site was confirmed pathologically and reviewed within the multidisciplinary head- and- neck team As part of the study, the ... of radiotherapy, and of these patients experienced in-field recurrences of the total of 20 cases of LRR occurred in the group of patients who had had a less than CR to nonsurgical treatment and ... patients Analysis of patterns of failure in relation to the dosimetry of the radiotherapy plan, demonstrated that 76% of LRR occurred within the PTV (12 of 14 local recurrences and of 11 regional...
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Báo cáo khoa học: "Parotid gland-recovery after radiotherapy in the head and neck region: 36 months follow-up of a prospective clinical study" pdf
... in terms of parotid gland sparing The IMRT technique should therefore represent the standard of care for the treatment of head and neck tumors Parotid-gland-sparing up to mean doses of 26 Gy ... significantly impact on the Dmean of the parotids, and thus on the saliva flow and recovery of parotid gland Keywords head and neck cancer; irradiation, saliva; hyposalivation; parotid gland sparing; ... circumstances that the protection of at least one single parotid is achieved either with 3DCRT and IMRT Depending on the radiation dose to the salivary glands the time of recovery of the parotid glands should...
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Báo cáo khoa học: "Intensity-Modulated Radiotherapy for Squamous Cell Carcinoma of the Anal Canal: Efficacy of a Low Daily Dose to Clinically Negative Regions" ppsx
... Reviewed charts, gathered data, and drafted the manuscript M.G.H.: Aided in the design of the study, helped draft the manuscript D.W.L.: Aided in the design of the study, helped draft the manuscript ... (3) The first 45 Gy of radiotherapy were concomitant with the first cycles of chemotherapy and used parallel opposed fields and a daily fraction of 1.80 Gy After 30.6 Gy was administered, the ... Radiotherapy and concurrent FU and MMC is the current standard of care and allows many patients to avoid having a colostomy Several prospective trials on chemoradiotherapy have been performed in the...
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Báo cáo khoa học: " Optimal organ-sparing intensity-modulated radiation therapy (IMRT) regimen for the treatment of locally advanced anal canal carcinoma: a comparison of conventional and IMRT plans" ppsx
... V20 of 59% and V10 of 73% It is possible that sparing of the femoral heads and/ or other organs comes at the cost of increasing dose to the iliac crests The results of our study reinforce the ... around the PTV Six and 18 MV photons were used for the AP and PA fields, respectively The radiation dose was prescribed to the PTV, such that 100% of the PTV received > 95% of the prescribed dose and ... IMRT, and 7-field IMRT integrated boost plans were generated The volume of bowel and bladder receiving threshold doses were similar to ours, but the V45 of the femoral heads is 0% in both of their...
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Báo cáo y học: "Adherence with urate-lowering therapies for the treatment of gout" pps
... interpretation of the data, and critiquing of drafts of this article BB was involved in the design of this project, analysis and interpretation of the data, and critiquing of drafts of this article ... interpretation of the data, and drafting of this article IO was involved in the conception and design of this project, analysis and interpretation of the data, and critiquing of drafts of this article ... content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute of Arthritis and Musculoskeletal and Skin Diseases or the National...
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