deformations in mechanisms and load distribution over the mated surfaces of parts
Báo cáo y học: "Antibody-induced arthritis: disease mechanisms and genes involved at the effector phase of arthritis" ppsx
... receptor-4-induced immune responses [112], indicating the complexity of interactions in the immune response The possible interactions of immune effector cells in the inflammatory phase of the arthritic ... enhances the incidence and severity of the antibody initiated disease by decreasing the threshold for arthritis induction, bypassing epitope specificity, and increasing pro-inflammatory mediators and ... drive the disease to the chronic stage, with complete distruption of joint architecture Thus, dissecting the fine specificity of the molecules taking part in the pathogenesis and understanding...
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báo cáo khoa học: "Gene-expression and network-based analysis reveals a novel role for hsa-mir-9 and drug control over the p38 network in Glioblastoma Multiforme progression" ppsx
... levels of each of the genes in the interaction and on the quality of the interaction The analysis takes into consideration the specific type of interaction (such as inhibition or promotion) The ... measure of the likelihood that the interaction occurs in the pathway When taking a pathway with two genes as input and one gene as output, the algorithm calculates their probability of being in an ... (by taking into account the expression levels of those genes in all the samples) The activity of this pathway is the probability that this interaction is "active", meaning the product of the probabilities...
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Báo cáo y học: " Epidemiologic heterogeneity of common mood and anxiety disorders over the lifecourse in the general population: a systematic review" ppsx
... of the sample, the sample size, the authors, and the study design in the first column, the age group of the sample in the second column, the timeframe of interviews in the third column, and the ... of symptoms of anxiety [51] A study of boys enrolled in the WIC program in Pittsburgh also identified four trajectories of symptoms of anxiety, including low, low-increasing, highdeclining, and ... heterogeneity in the longitudinal trajectories of mood and anxiety disorders Second, there may be true intra-individual heterogeneity in the longitudinal course of a single clinical disorder because of...
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Báo cáo y học: "PKC and PKA Phosphorylation Affect the Subcellular Localization of Claudin-1 in Melanoma Cells"
... opens up the possibility that Wnt signaling is involved in claudin-1 expression and localization 99 Indeed, a study shows that increasing β-catenin increases the expression of claudin-1 in colorectal ... that active PKC may exist in the nucleus of melanoma cells, and the presence of active PKC isoforms in the nuclei of many cell types has been confirmed (10-12) Staining of the G361 cells with antibodies ... expression of claudin-1 in the cytoplasm, with some nuclear expression of claudin-1 B) Treatment of these cells with PKA inhibitor results in nuclear translocation of claudin-1 in as little as 15 minutes,...
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Báo cáo khoa học: Characterization of a cathepsin L-associated protein in Artemia and its relationship to the FAS-I family of cell adhesion proteins pot
... Comparison of the fasciclin I domains in CLAP with selected proteins in the protein database The Conserved Domain Database of NCBI was screened with the protein coding sequence of clone of CLAP and the ... represent the pI values of the major bands in e and f, while the numbers at the left are the pI values of standard proteins The arrow at the right represents the pI value of 6.84 calculated for the ... Processing of the pro-CLAP C-terminus is essential to lower the molecular mass and pI of the protein to values observed by SDS/ PAGE and IEF Interestingly, pool sequencing of the mixture of CNBr...
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Effects of compost and phosphate amendments on arsenic mobility in soils and arsenic uptake by the hyper
... the absence of the fern, but decreased in the presence of the fern For the ASC soil, both treatments reduced As leaching regardless of the presence of the fern The results indicate that growing ... of the CCA soil was probably due to the similar pH of the soil and each of the amendments The application of the neutral pH amendments increased pH of the acidic ASC soil at first However, there ... arsenic and minimize arsenic leaching However, whether the increased plant will balance leaching from the top soil remains unclear The overall objective of this study was to determine whether soil...
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Báo cáo khoa học: Tumour necrosis factor-a attenuates insulin action on phosphoenolpyruvate carboxykinase gene expression and gluconeogenesis by altering the cellular localization of Foxa2 in HepG2 cells pptx
... a series of events beginning with the TNFa-mediated prevention of the effect of insulin on Foxa2 localization and leading to the abrogation of insulin inhibition of gluconeogenesis and glucose ... status in the presence and absence of insulin and ⁄ or TNFa Figure 2A, B shows the effects of TNFa pretreatment on insulin action on the localization of Foxa2 and Foxo1 within the cell Incubation ... by insulin for these time periods Control cells were incubated in the absence of any of these agents On termination of incubation, the glucose released in the medium was assayed as described in...
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Paper Manufacture in Central and Eastern Europe Before the Introduction of Paper-making Machines pptx
... as Polish The Union of Lublin (1569) united the Grand Duchy of Lithuania and the Kingdom of Poland into the ‘Commonwealth’ (Rzeczpospolita) in which Podlasie and the palatinates of Ukraine (Volhynia, ... stock in the vat, speeded up the manufacture of paper by increasing the dewatering rate of the stock during forming the sheet of paper As perceived in the picture by Porcelius, both the vatman and ... much to the development of making paper by hand in central and eastern parts of Europe, introduced to their new home-lands also their terminology of papermaking and their customs Some information...
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Báo cáo sinh học: " Possible active origin of replication in the double stranded extended form of the left terminus of LuIII and its implication on the replication model of the parvovirus" pptx
... analysis and interpretation of the data, participated in the idea and design of the models proposed and in the drafting and revision of the manuscript IDM collected the data resulting from the transfections ... (figure 1) In anticipation of the difficulties expected in manipulating the left end hairpin and to increase the chances of obtaining the desired construct two copies of the left end termini were ... essential cofactor for NS1 in the replication initiation process allowing efficient and specific nicking of the 3' minimal origin and leaving NS1 covalently attached to the 5' end of the DNA at the...
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báo cáo hóa học:" Possible active origin of replication in the double stranded extended form of the left terminus of LuIII and its implication on the replication model of the parvovirus" ppt
... analysis and interpretation of the data, participated in the idea and design of the models proposed and in the drafting and revision of the manuscript IDM collected the data resulting from the transfections ... (figure 1) In anticipation of the difficulties expected in manipulating the left end hairpin and to increase the chances of obtaining the desired construct two copies of the left end termini were ... essential cofactor for NS1 in the replication initiation process allowing efficient and specific nicking of the 3' minimal origin and leaving NS1 covalently attached to the 5' end of the DNA at the...
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Highway Bridge Loads and Load Distribution doc
... all loads from superstructure elements within half the distance to the adjacent girder This includes the dead load of the girder itself and the soffit, in the case of box girder structures The ... N/mm and emulates a caravan of trucks Similar to the truck loading, the lane load is spread over a 3-m-wide area in the standard 3.6-m lane The lane loading is not interrupted except when creating ... loaded, and when more than one lane is loaded L1 is the lesser of the actual span or 18,000 mm, W1 is the lesser of the edge-to-edge width of bridge and 18,000 mm in the case of single-lane loading,...
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Báo cáo y học: "Expression of cytokine mRNA and protein in joints and lymphoid organs during the course of rat antigen-induced arthritis" potx
... the study, including the animal experiments RWK contributed to the design of the study, including the animal experiments, and participated in the layout, writing, and finalization of the manuscript ... arthritogen, and on days 1, 3, and of the disease, the latter time point marking the transition to the chronic phase For the sake of clarity, individual cytokines are assigned to monokine- and Th1-/Th2-like ... injections into both flanks of the animals On day 0, AIA was induced by intra-articular injection of 100 µg mBSA in 50 µl of PBS into the right R446 knee joint; the left knee received 50 µl of...
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Báo cáo khoa học: "Job stress and job satisfaction of physicians, radiographers, nurses and physicists working in radiotherapy: a multicenter analysis by the DEGRO Quality of Life Work Group" ppt
... suggest that the stress does not get better after completion of training Efforts to debunk the myth of "things getting better" early in training and instead emphasize the importance of developing balance ... levels than the other professional groups With the aging of the population there will be a growing demand to recruit health care professionals -especially in oncology On the other hand birth rates ... [10] In oncology additional strain is produced by the frequency of the deliverance of bad news and dealing with patient's death and suffering [11] These imbalances with increasing demand of human...
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báo cáo khoa học: " Comparison of hyperthermia and adrenaline to enhance the intratumoral accumulation of cisplatin in a murin model of peritoneal carcinomatosis" potx
... performed in anaesthetized rats (isoflurane inhalation as induction and then 100 mg/kg of intramuscular ketamine and 15 mg xylazine into the back leg for maintenance) to check the presence of a peritoneal ... and resulting in an increase in the wash out of the cisplatin [33] In contrast with heat, adrenaline at a concentration of mg/l for hour achieved a to 3-fold increase in platinum content in the ... sampled and kept at -80° C until the platinum assay The comparison of groups and should assess the effect of hyperthermia; that of groups and should assess the effect of adrenaline; and that of groups...
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Báo cáo khoa học: "Pro/con debate: In patients who are potential candidates for organ donation after cardiac death, starting medications and/or interventions for the sole purpose of making the organs more viable is an acceptable practice" doc
... believe that starting certain medications and interventions such as inotropes, vasopressors, heparin and phentolamine in potential donors for the sole purpose of making the organs in DCD more viable ... equal proof of absence of harm; the incidence of harm from heparin is credible and has not been systematically examined A standard of practice to use heparin without good clinical evidence of benefit ... The ethical principle of the ‘rule of double effect’ provides moral justification for the provision of certain forms of care at the end of life that result in death [11] A practical example of...
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Báo cáo y học: "Modelling the relationship between obesity and mental health in children and adolescents: findings from the Health Survey for England 2007" pptx
... reviewing and contributed to the writing of the report HJM contributed to appraising the content and the writing of the report CDS contributed to the supervision and conceptualisation of the project ... psychological wellbeing was restricted to the parentally reported SDQ, in the absence of the SDQ impact supplement The use of SDQ internalising and externalising factor scores as the main outcome measure ... hereditary in nature), interacting with early environment gives rise to a tendency to dysphoric mood and low self-esteem that increases the risk of over- eating The reasons for the non-linearity of the...
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Báo cáo y học: " Influence of genetic variations in TLR4 and TIRAP/Mal on the course of sepsis and pneumonia and cytokine release: an observational study in three cohorts" pdf
... heterozygous and homozygous The distribution of SNPs in the studied Page of 11 patients and the cohort of healthy controls is shown in detail in Table Clinical influence of genotypes on postoperative infection ... affecting the capability to sense invading microorganisms, but rather the appropriate initiation and modulation of the innate immune response These findings are supported by the fact that following ... risk of severe infections and a combination of genetic variants in sequential molecules of the LPS-sensor consisting of TLR4 and its adaptor TIRAP/Mal The presence of TLR4 mutations in combination...
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Báo cáo sinh học: " Further insights of the variance component method for detecting QTL in livestock and aquacultural species: relaxing the assumption of additive effects" pptx
... of detecting dominance in the second stage, according to the conditional model (first estimating the most likely position of the QTL using the ADDITIVE and GENOTYPIC model and then fitting dominance ... of the test statistic under the null hypothesis of no QTL, obtained using the GENOTYPIC test The total number of individuals is equal to 500 The horizontal line is the 95% of the cumulative distribution ... between the empirical distribution obtained here and the distribution of the LR under the null hypothesis, as obtained previously by others [27] For the GENOTYPIC test (including additive and dominance...
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unmarked plural nouns in english and theis difficulties for the 1st year students at the faculty of tourism, honoi university of culture = danh từ số nhiều không có dấu hiệu nhận dạng trong tiếng anh tt
... language skills: reading, speaking, writing and listening As the final aim of learning language in general and learning English in particular is communicative, vocabulary is one of the most essential ... description of the subjects, the instruments, and procedures for the study 4.1 The subjects There are two types of subjects participating in the study The first type is the 1st year students at the Faculty ... like the following are used after the to represent a group as a whole such as the blind, the deaf, the dead, the rich, the poor, the young, the old, the unemployed, etc (ii) the + adjectives of...
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Tìm thêm: xác định các mục tiêu của chương trình khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha thông tin liên lạc và các dịch vụ từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25