... T cells slowly decreases while plasma viremia rises in most patients If sequential analysisofthe lymphoid tissue is performed, progression ofthe disease is reflected by destruction ofthe lymphoid ... versus fast disease progression These studies suggest that the HLA type could be responsible for the benign course of disease in about 40% of patients with a long-term non-progressive course of ... days The severity and duration of symptoms has prognostic implications, as severe and prolonged symptoms are associated with more rapid disease progression The nonspecific nature ofthe symptoms...
... storage also adds a more professional appearance for such remote locations as closets, basements, CEVs, and other tight spaces The rack-mount chassis includes cable support bars on the rear for ... affords greater flexibility in providing service to customers The Extend chassis supports 24 plug-in modules and, with advanced heat dissipation features, does not require use of valuable rack space ... optical fibers can be safely routed to splice decks and storage trays The second factor that helped gain approval ofthe Extend O/E Line Extender was density ofthe rack mount chassis, a feature...
... invention ofthe telescope and the discovery of sunspots, that the systematic scientific study ofthe Sun began, withthe discovery ofthe sunspot cycle and the application ofthe new science of spectroscopy ... heliosphere These objectives will be addressed by a Solar Probe mission Because ofthe importance of these objectives for the overall understanding ofthe solar-heliosphere system, as well as of other stellar ... and the interstellar medium and will change as these pressures vary At this point in the history ofthe solar system, most ofthe changes in the dimensions ofthe heliosphere probably result...
... invention ofthe telescope and the discovery of sunspots, that the systematic scientific study ofthe Sun began, withthe discovery ofthe sunspot cycle and the application ofthe new science of spectroscopy ... heliosphere These objectives will be addressed by a Solar Probe mission Because ofthe importance of these objectives for the overall understanding ofthe solar-heliosphere system, as well as of other stellar ... and the interstellar medium and will change as these pressures vary At this point in the history ofthe solar system, most ofthe changes in the dimensions ofthe heliosphere probably result...
... report is structured as follows: Section summarises the key results oftheanalysis in terms of projected GDP levels, growth rates and average income trends to 2050 Section discusses the potential ... analysis and stress testing We create scenarios and risk frameworks to help companies understand the risks and opportunities in their business and plan for them Impact analysis We help clients demonstrate ... Energy intensity Source: PwC analysis (last two rows are approximate estimates only based on IPCC AR4 report ranges) The first ‘business as usual’ scenario projects forward the experience ofthe 2000-11...
... calorie results, low-calorie diners had the highest health consciousness scores, on average, yet the difference in health consciousness scores across the three diner groups was much smaller Finally, ... consciousness were also compared across the categories of diners as well as the proportion of people who responded that taste or health was the most important characteristic when making a menu selection ... Summing the values across the three questions provided a person s level of health consciousness; scores could range from three to fifteen, with fifteen representing the most health conscious consumer...
... context ofthe exercise workflow So, for example, a discussion about designing buttons leads to a discussion of effects, which leads to a discussion of object styles Each chapter builds on the last, ... Serif fonts are fine for headers or typographical accents, but you want to stick with sans-serif fonts for your body text RR Serifs Sans-serif (No serifs) Serif and sans-serif fonts Sans-serif font ... always comprise two hexadecimal digits As withthe base 10 system, the first digit represents the number of times the base number, in this case 16, goes into a given value (0 - 255) and the second...
... at the level of standard-setting may be achievable through the use of consensus-based techniques by narrowing the focus of activity to a highly specific level But as soon as the effects of consensual ... effects and seriously jeopardise the stability ofthe entire system For example, the Basel Committee on banking supervision, comprised of central bank governors from ten states, does not possess ... disparities in the implementation of supranational legal norms While many have applauded the success ofthe WTO dispute resolution system, there have also been considerable criticisms These criticisms...
... have the disease If screened individuals are assigned a position in a two-by-two classification scheme on the basis of their disease status and test result, values for the three measurements can ... maintenance ofthe specimen banks, and specimen banks supported by government funds should not place excessive restrictions on the use ofthe specimens with regard to intellectual property issues Consistent ... expression in cancer cellsa Used as research tools Used as research tools Used as research tools Preclinical stage DNA arrays Identify polymorphisms associated with cancer risk In clinical use...
... factors in cellular senescence through the p53–p21 and JNK pathways [91] LC8 interacts withthe transcription factor TRPS1 and suppresses its transcriptional repression activity [92] LC8 binds to the ... His41 in DYNLL2) [21] In vitro the two LC8 isoforms bind the targets withthe same affin- ity The molecular surface around the ‘specificity residue’ might make contacts with other components of their ... complexes via antiparallel b-strands ofthe ligands has been observed hitherto only as a crystal contact in the crystal structure ofthe LC8–EML3 complex Subunits of LC8 are colored as in Fig 1; the...
... track sheet, in the hands ofthe individuals we call trackers Trackers are the field researchers ofthe science of shopping, the scholars of shopping, or, more precisely, of shoppers Essentially, ... was easier to read the song lists and see the photos, so cassette shoppers would browse in LPs, make up their minds, and then go to the tapes section to find their choices Our suggestion was ... singleS 45 rpm records-were still big sellers The store, wisely, displayed the Billboard magazine ch~rt of bestselling singles near the racks of records, as a stimulus to sales But our film showed...
... efforts—against polio, measles, and other diseases—have saved the lives of millions of children over the years and prevented lifelong illness that often comes with childhood diseases.42 CDC has played ... outcomes.57,58 With an emphasis on mass drug administration to address these diseases, the NTD Initiative reports that 50% ofthe recipients were women.36 THE U .S GOVERNMENT S EFFORTS TO ADDRESS GLOBAL ... deaths These initiatives are largely focused on sub-Saharan Africa, where the greatest burdens of these diseases as well as maternal and child mortality exist, but—in the case of PEPFAR and the...
... classic, without the help and against the active hostility ofthe professionals of taste; and has furthermore largely created the expectations and established the conventions of a new and flourishing ... Tales The Lays of Beleriand The Shaping of Middle-earth The Lost Road The Return ofthe Shadow The Treason of Isengard The War ofthe Ring Sauron Defeated: The End ofthe Third Age 10 Morgoth s ... Lord ofthe Rings The purpose ofthe book, they state, is “to help fans ofThe Lord ofthe Rings discover how the rich fabric of Tolkien s fantasy world enhances a Christian understanding of our...
... parameters suggests these measures may be useful biomarkers for assessing the clinical activity of this new cancer immunotherapy Session finished with a panel discussion led by Disis, Puri, Stroncek, ... predictors for clinical response The utility of these biomarkers has been limited by the small size of most of these trials, limited clinical response and by the fact that biomarker analysis is often ... biomarkers to assess the effect of immune-based cancer therapies is important for several reasons First, immune-based treatments, such as vaccines, are often designed to elicit a specific response so...
... achieve sustainable growth of poor countries In light of these limitations, some critics ofthe current aid system suggest that the ‘Big Push’ approach will not solve the problems the MDGs seek ... natural resources and labor to western states [30] As another example ofthe globalised nature of risks, the recent food crisis left many poor farmers unable to Page of sell their crops after a ... Health Partnership, and the related ‘joint assessment of national strategies’ processes can be used as a reference,[58] if it includes civil society as the Global Fund s decisional platforms [57] Both...
... paralogous pairs Numbers of synonymous substitutions (syn), non-synonymous substitutions (nonsyn), synonymous (dS) and non-synonymous (dN) substitutions rates, substitutions in intronic regions (subst/intron), ... genes in Leersia is not surprising considering its position in our trees, where all copies of all amplified sequences from this species are grouped in the same clade as the Oryza species For sequences ... Biosci 1996, 12:543-548 Swofford DL: PAUP* Phylogenetic Analysis Using Parsimony (*and Other Methods) Version Sinauer Associates, Sunderland, Massachusetts; 2003 Simmons MP, Ochoterena H: Gaps...
... recommendations (0.7 infections/1000 days versus 5.0 infections/1000 days of catheter use; P < 0.03) [15] Clinical management of sepsis is normally outside the remit of this section ofthe journal ... intensivists, its technology is innovative and its proposed status as an ‘online second opinion’ may give it, together with similar expert systems, a powerful consumerist resonance with patients, ... http://ccforum.com/content/9/1/12 successful convergence of multiple hospital systems, which makes them uniquely vulnerable to the consequences of system failures, whether in diagnostics, supplies, information...
... publication of results initially presented in abstracts: a meta -analysis JAMA 1994, 272:158-162 Kelly JA: Scientific meeting abstracts: significance, access, and trends Bull Med Libr Assoc 1998, ... minute historical details critical to a legal contest, I wished fervently for the existence of an open access, easily searchable, repository of meeting abstracts Retrovirology is committed to the ... Instituteof Human Virology Retrovirology 2005, 2(Suppl 1S1 [http:// www.retrovirology.com/supplements/2 /S1 ] Freed EO, Ross SR: Retroviruses 2004: Review ofthe 2004 Cold Spring Harbor Retroviruses conference...