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composition synthesis and biochemical action

synthesis and optical properties of au-ag alloy nanoclusters with controlled composition, p26

synthesis and optical properties of au-ag alloy nanoclusters with controlled composition, p26

Vật lý

... type and composition of bimetallic nanoparticles comprised of Ag and Au have been a subject of considerable interest; and the developed of simple and versatile methods for controlling the composition ... frequency and intensity of SPR band depend on the size, shape, structure and composition [39,40,45] of the metal nanoparticles While the techniques like TEM, HREM reveal the exact size and shape ... quick and gross idea on their shapes and sizes In this study we used TEM, HREM and HAADF, along with optical absorption spectroscopy to study the size, size distribution, fine structure and composition...
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Agents for hepatocellular carcinoma synthesis and mode of action

Agents for hepatocellular carcinoma synthesis and mode of action

Kỹ thuật - Công nghệ

... 2-1: General synthesis pathway for Series to 7, 8-1, 8-3 and 8-7 Scheme 2-2: Knoevenagel reaction between benzaldehyde and malonic acid Scheme 2-3: Reaction sequences involved in synthesis of ... bonds in 47 and guandinium side chain of Arg 97 and carbonyl O of Ser 263 Figure 4-10: H bonding between (A) sulfonyl O atoms of 3-12 and Arg 97, Ser 263 Phe 96; (B) Nitro O atoms of III and Ser ... the synthesis of 3-benzylidene indolin-2-ones of 58 2.6.4 Synthesis of sulfamoyl and N-substituted sulfamoyl benzoic acids 58 2.6.5 Synthesis of formyl benzenesulfonamides 59 2.6.6 Synthesis...
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Investigations into the chemopreventive potential of stilbenes, indolinones and isoindigos  synthesis and mode of action studies

Investigations into the chemopreventive potential of stilbenes, indolinones and isoindigos synthesis and mode of action studies

Cao đẳng - Đại học

... Professor Loh Teck Peng and his postgraduate students Zhao Yu Jun and Shen Zhi Liang for invaluable discussions and suggestions for organic synthesis I want to thank Oh Tang Booy and Ng Sek Eng for ... methoxy groups on ring A and B, (ii) bulky alkoxy groups on ring B, such as phenoxy and 3,4,5-trimethoxy, and (iii) chloro, fluoro and trifluoromethyl groups on rings A and B These compounds arrested ... Class and compounds (1-50) were synthesized by a Knoevenagel-type reaction between an aldehyde and oxindole (Scheme 2-6) Scheme 2-6: Synthetic pathway for Class and compounds (1-48), 49 and 50...
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Antiproliferative activity of curcumin analogs on acute promyelocytic leukemia   synthesis and mode of action studies

Antiproliferative activity of curcumin analogs on acute promyelocytic leukemia synthesis and mode of action studies

Tổng hợp

... compounds were synthesized and evaluated on two APL cell lines (NB4 and NB4-R1), two leukemic non-APL cell lines (HL60 and K562) and two nonmalignant cell lines (IMR90 and MCF10A) An assessment ... selective and APL non-selective compounds 112 4.3.2 N-CoR accumulated is in the misfolded state 116 4.3.3 Investigations on the interaction of curcumin and APL selective compounds 11, 22 and ... cells 146 5.3.4 Effects of 41, 219 and 227 on the ER stress sensors PERK and IRE2 .148 5.3.5 Effects of 41, 219 and 227 on apoptotic markers caspases 3, and PARP 151 5.4 Discussion...
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Tài liệu Global Farming Systems Study: Challenges and Priorities to 2030 SYNTHESIS AND GLOBAL OVERVIEW doc

Tài liệu Global Farming Systems Study: Challenges and Priorities to 2030 SYNTHESIS AND GLOBAL OVERVIEW doc

Nông nghiệp

... access to and control of natural resources – particularly land and water As populations increase and marginal lands suffer increasing levels of degradation, the demands of poorer, minority and indigenous ... development in these areas is to arrest land degradation and to improve income and living standards through soil and water conservation, integrated crop and livestock husbandry, agroforestry, introduction ... Asia and the Pacific Since the 1960s, pasture and grazing land has expanded, by 15 percent globally, to about 2.2 billion in 1994 Some of this expansion came at the expense of forest and woodland,...
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Tài liệu Adult environmental education: awareness and environmental action pdf

Tài liệu Adult environmental education: awareness and environmental action pdf

Sức khỏe giới tính

... change and initiate action Such projects go beyond creating understanding and awareness They aim at developing skills, creating a sense of commitment and stimulating individual and collective action ... health and population Booklets under this theme: 6a Adult environmental education: awareness and environmental action 6b Health promotion and health education for adults 6c Adult education and population ... their environment and acquire the knowledge, values, skills, experiences, and also the determination which will enable them to act individually and collectively to solve present and future environmental...
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Tài liệu How to accelerate graphics and computationIN ACTIONMatthew ScarpinoMANNING.OpenCL in docx

Tài liệu How to accelerate graphics and computationIN ACTIONMatthew ScarpinoMANNING.OpenCL in docx

Kỹ thuật lập trình

... arguments 182 ■ 8.4 Command queues 173 ■ Local 183 Creating CommandQueue objects 183 Enqueuing kernelexecution commands 183 Read/write commands 185 Memory mapping and copy commands 187 ■ ■ 8.5 Event ... how host applications are coded, and chapters and discuss kernel coding Chapters and explore the advanced topics of image processing and event handling Chapters and discuss how OpenCL is coded ... from, and the basics of its operation Chapters and explain how to code applications that run on the host, and chapters and show how to code kernels that run on compliant devices Chapters and explore...
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Tài liệu The Financial Crisis: A Timeline of Events and Policy Actions ppt

Tài liệu The Financial Crisis: A Timeline of Events and Policy Actions ppt

Tài chính doanh nghiệp

... investors, servicers, mortgage market participants, and credit and homeowners’ counselors encouraged by the Treasury Department and the Department of Housing and Urban Development Page of 32 October 15, ... Treasury/FHFA and Fannie Mae and Freddie Mac to ensure the GSEs positive net worth; 2) a new secured lending facility which will be available to Fannie Mae, Freddie Mac, and the Federal Home Loan Banks; and ... Federal Reserve Press Release The FOMC expands existing swap lines by $180 billion and authorizes new swap lines with the Bank of Japan, Bank of England, and Bank of Canada Page of 32 September...
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Tài liệu Báo cáo khoa học: The crystal structure of human a-amino-b-carboxymuconatee-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis ppt

Tài liệu Báo cáo khoa học: The crystal structure of human a-amino-b-carboxymuconatee-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis ppt

Báo cáo khoa học

... residues and solvent molecules engaged in ligand recognition and stabilization are drawn as balls -and- sticks and spheres, respectively The major interactions established between the DHAP inhibitor and ... ligand O1 and O1P ˚ atoms at 2.5 and 2.8 A, respectively Moreover, the ligand is engaged in a number of stabilizing interactions with the protein milieu by contacting both protein residues and ... expression profile and the associated variation in QA and PA levels [7], and other investigations have clearly demonstrated that changes in ACMSD activity are readily reflected by serum and tissue QA...
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Tài liệu Báo cáo khoa học: Structure determination and biochemical studies on Bacillus stearothermophilus E53Q serine hydroxymethyltransferase and its complexes provide insights on function and enzyme memory doc

Tài liệu Báo cáo khoa học: Structure determination and biochemical studies on Bacillus stearothermophilus E53Q serine hydroxymethyltransferase and its complexes provide insights on function and enzyme memory doc

Báo cáo khoa học

... the structure of E53QbsSHMT and its binary complexes with Gly, l-Ser, l-allo-Thr and ternary complex with Gly and 5-formyl-THF (FTHF) In addition, the biochemical and spectral properties of these ... group and contained one monomer in the asymmetric unit Cell dimensions and details of data collection are shown in Table Expression and purification of bsSHMT and E53QbsSHMT The expression and purification ... one containing the enzyme (500 lm) and the other containing Gly (100 mm) or Gly and THF (70 lm) or Gly and FTHF (200 lm) The contents were mixed and the reaction was initiated Single wavelength...
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Tài liệu Báo cáo khoa học: Tissue expression and biochemical characterization of human 2-amino 3-carboxymuconate 6-semialdehyde decarboxylase, a key enzyme in tryptophan catabolism pptx

Tài liệu Báo cáo khoa học: Tissue expression and biochemical characterization of human 2-amino 3-carboxymuconate 6-semialdehyde decarboxylase, a key enzyme in tryptophan catabolism pptx

Báo cáo khoa học

... curves and data were normalized to the copy number of 18S RNA Expression of ACMSD isoforms in E coli pGEM-ACMSD I and pGEM-ACMSD II were digested with XhoI and Bpu1102I and cloned into pET-15b and ... swiss-pdbviewer and visual molecular dynamics [49] Acknowledgements We thank G Magni and S Ruggieri for helpful comments and suggestions and T Begley (Department of Chemistry and Chemical Biology, ... Escherichia coli and Pichia pastoris ACMSD I and II cDNAs were subcloned into pET15b and pET32b E coli expression vectors, providing the recombinant proteins with a N-terminal His6-tag, and a thioredoxin-tag,...
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Tài liệu Báo cáo khoa học: Structural and biochemical characterization of a human adenovirus 2/12 penton base chimera pptx

Tài liệu Báo cáo khoa học: Structural and biochemical characterization of a human adenovirus 2/12 penton base chimera pptx

Báo cáo khoa học

... insertion of $ 230 residues (residues 133–367) between strands D and E and a smaller insertion of $ 50 residues (residues 404–458) between strands F and G The hypervariable loop, FEBS Journal 273 (2006) ... expression, the SF21 and Hi5 cell lines and the Bac-to-Bac expression system and vectors were from Invitrogen (Carlsbad, CA, USA) Protease inhibitors were from Roche (Basel, Switzerland) and Ni-NTA resin ... penton base (yellow), hAd2 ⁄ 12 (blue), and hAd2 fiber peptide complex (pink) The fiber peptide is drawn as ball -and- stick and colored by atom fiber peptide bound and unbound structures reveal a high...
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Tài liệu Báo cáo khoa học: Molecular and biochemical characterization ofD-phosphoglycerate dehydrogenase fromEntamoeba histolytica A unique enteric protozoan parasite that possesses both phosphorylated and nonphosphorylated serine metabolic pathways docx

Tài liệu Báo cáo khoa học: Molecular and biochemical characterization ofD-phosphoglycerate dehydrogenase fromEntamoeba histolytica A unique enteric protozoan parasite that possesses both phosphorylated and nonphosphorylated serine metabolic pathways docx

Báo cáo khoa học

... a limited set of enzymes involved in amino acid synthesis of Ser from Gly and Ala from Cys and conversions between Asp and Asn and between Glu and Gln [49] Serine metabolic pathways are often ... mM) and NAD+ (5.0 lM to 0.3 mM) The reaction was initiated by the addition of 3-PGA The PGDH activity in the reverse reaction was measured both fluorometrically and spectrophotometrically The reaction ... cyanobacteria, Clostridiales, Actinomycetales and archaebacteria belong to Type I, while b- and c-proteobacteria and Bacteroidales belong to Type IIA and Type III, respectively It is worth noting...
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Tài liệu Báo cáo khoa học: Specific targeting of a DNA-alkylating reagent to mitochondria Synthesis and characterization of [4-((11aS)-7-methoxy-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-on-8-oxy)butyl]-triphenylphosphonium iodide doc

Tài liệu Báo cáo khoa học: Specific targeting of a DNA-alkylating reagent to mitochondria Synthesis and characterization of [4-((11aS)-7-methoxy-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-on-8-oxy)butyl]-triphenylphosphonium iodide doc

Báo cáo khoa học

... binding and selective alkylation leading to a depletion of mtDNA in intact cells (Fig 1) Here we report the synthesis and characterization of a novel mitochondria-targeted alkylating reagent and ... mmol) in dimethylformamide (0.2 mL) and tetrahydrofuran (0.2 mL) was added dropwise to the reaction vessel and stirred for 3.75 h, after which time the reaction mixture was a yellow/brown suspension ... liver mitochondria (40 mg protein) and incubated with 500 lM mitoDC-81 for h and then cut with ClaI (C and D) DNA was separated by electrophoresis on an agarose gel and the ethidium bromide fluorescence...
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Tài liệu Báo cáo Y học: Phosphatidylinositol synthesis and exchange of the inositol head are catalysed by the single phosphatidylinositol synthase 1 from Arabidopsis docx

Tài liệu Báo cáo Y học: Phosphatidylinositol synthesis and exchange of the inositol head are catalysed by the single phosphatidylinositol synthase 1 from Arabidopsis docx

Báo cáo khoa học

... catalysing several enzymatic reactions: PtdIns de novo synthesis, using CDP-DAG and free inositol as substrates and producing PtdIns and CMP; a CMP-independent exchange reaction whereby the inositol ... without net synthesis of PtdIns; a CMP-dependent exchange reaction, far greater in quantitative terms than the CMP-independent one; and, finally, a reaction which is the reverse of synthesis, dependent ... reaction and what the exact mechanism for exchange is Our data does not allow us to distinguish between a reverse reaction followed by re -synthesis, as suggested by Paulus & Kennedy [19], and...
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Tài liệu Báo cáo Y học: Structural and biochemical characterization of neuronal calretinin domain I– II (residues 1– 100) Comparison to homologous calbindin D28k domain I–II (residues 1 –93) pdf

Tài liệu Báo cáo Y học: Structural and biochemical characterization of neuronal calretinin domain I– II (residues 1– 100) Comparison to homologous calbindin D28k domain I–II (residues 1 –93) pdf

Báo cáo khoa học

... for both CR and Calb [22,24,30] The biochemical properties of CR and Calb are similar to those of calmodulin, the best-known EF-hand calcium sensor It is difficult to localize the biochemical ... us to analyze the biochemical and structural properties of CR I– II and to compare them with Calb I–II Our data show that CR I –II and Calb I –II share virtually the same EF-hand structures However, ... underlined An EF-hand consensus sequence is placed between the aligned EF-hand I and EF-hand II sequences [3] The helices are shown as boxes with conserved hydrophobic (h) and other amino acids...
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Báo cáo khoa học: Proteomic and biochemical analysis of 14-3-3-binding proteins during C2-ceramide-induced apoptosis pot

Báo cáo khoa học: Proteomic and biochemical analysis of 14-3-3-binding proteins during C2-ceramide-induced apoptosis pot

Báo cáo khoa học

... (EX), wash (W) and eluted (EL) fractions were subjected to 10% SDS ⁄ PAGE, and silver stained Arrows indicate bands in both eluted fractions that showed differences in control and C2-ceramide-stimulated ... undergo direct interactions with 14-3-3 proteins TSC2 also showed a direct interaction with 14-3-3 proteins, supporting previous results [72], and giving confidence in this technique Biochemical validation ... cells, and is implicated in the restoration of genomic integrity in response to DNA double-strand breaks [80] B23 negatively regulates p53 and antagonizes stress-induced apoptosis in human normal and...
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Báo cáo khoa học: Synthesis and function of ribosomal proteins – fading models and new perspectives pptx

Báo cáo khoa học: Synthesis and function of ribosomal proteins – fading models and new perspectives pptx

Báo cáo khoa học

... of the biosynthesis of ribosomes to the requirements of cell growth and differentiation In addition, a relevant contribution of protein turnover to the regulation of 3200 RP synthesis and accumulation ... mouse, and human) have amply demonstrated that the FEBS Journal 276 (2009) 3199–3210 ª 2009 The Authors Journal compilation ª 2009 FEBS S Caldarola et al Ribosomal protein synthesis Fig Synthesis and ... for proteins involved in cell proliferation (MIF and cenpA), survival (i.e survivin, BI-1, and dad1), and ribosome biogenesis (members of the small and large ribosomal subunits) Interestingly, not...
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Báo cáo khoa học: Protein transport in organelles: The composition, function and regulation of the Tic complex in chloroplast protein import pptx

Báo cáo khoa học: Protein transport in organelles: The composition, function and regulation of the Tic complex in chloroplast protein import pptx

Báo cáo khoa học

... membrane binding and integration into the Tic complex Reducing conditions on the other hand lead to solubilization into the stroma and increased interaction with its other known interaction partner ... [12] However, analysis of the interaction between Tic110, Cpn60 and imported preprotein revealed that only the interaction with the mature form is ATP-dependent and thus mediated by Cpn60 This suggests ... [10] These structures have been implicated with channel function (e.g in ligand-gated and voltage-gated K+ channels) [16], and thus could provide an explanation for the observed channel activity...
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