complete the sentence with the correct form of the verb ser juanita alta
Tài liệu Supply the correct form of the verbs1 docx
... live in a snake.14. My brother managed to kill the snake just at the time when I were almost exhausted. Supply the correct form of the verbs1. Cats could fly if they (have) wings.2. If Peter ... (not,want) to live in a snake.14. My brother managed to kill the snake just at the time when I (be) almost exhausted. Ifhe (be) a little late, I (kill) by the snake.15. Had I know you were ill, ... snake.14. My brother managed to kill the snake just at the time when I (be) had been almost exhausted. If he (be) had been a little late, I (kill) would have been killed by the snake.15. Had...
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Báo cáo khoa học: The pharmacological chaperone isofagomine increases the activity of the Gaucher disease L444P mutant form of b-glucosidase docx
... measures of dis-ease (e.g. reduced spleen weight, GC and plasmamarkers) were observed in only one of the 18 patientswho completed the study. The results of this trial pro-vide preliminary proof -of- concept ... c-octyldeoxynojorimycin[33]. As a result of the very low level of GCase activityin the L444P fibroblasts, alternative methods weredeveloped to reduce the amount of IFG in the assay,thereby increasing the overall sensitivity. ... cleared (Fig. 6), and support the long half-life of the enzyme. The inability to detectIFG in the brain of L444P GCase mice is most prob-ably a result of the dose of IFG tartrate administered(20...
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Báo cáo khoa học: An arginyl in the N-terminus of the V1a vasopressin receptor is part of the conformational switch controlling activation by agonist docx
... mutation of Arg46 had the dualeffect of (a) decreasing agonist affinity and (b) promoting the agonist-induced active conformation due to the loss of astabilizing constraint on the ground state of the ... Results The effect of systematic substitution of Arg46on agonist binding The structural requirements of the residue at position 46 in the N-terminus of the V1aR (Fig. 1) were investigated, with respect ... compared to the wildtype Arg46, with the precise value depending on the identity of the substituentamino acid (Fig. 5). These data establish that the mutantreceptors are much less likely than the wildtype...
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Economic Impact of the Abolition of the Milk Quota Regime – Regional Analysis of the Milk Production in the EU – doc
... on average, with +35.5% in the EU-10 and +13.8 in the EU-15. This excess supply makes the net trade position of the EU-27 stronger towards the Rest of the World. Within the EU there is a quite ... through either the transfer of an entire farm, the leasing or purchase of quota, or the allocation of quota from a national reserve. The transfer of milk quota may take place via a variety of administrative ... Impact of the Abolition of the Milk Quota Regime – Regional Analysis of the Milk Production in the EU" (AGRI-2007-0444). The project aimed at a thorough policy impact analysis of the EU...
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Báo cáo khoa học: Phosphorylation of the arginine/serine dipeptide-rich motif of the severe acute respiratory syndrome coronavirus nucleocapsid protein modulates its multimerization, translation inhibitory activity and cellular localization pptx
... copies of the N protein, respectively. (C) The RNA binding efficiency of N protein is represented as a percentage of bound RNA (i.e. the percentage of bound RNA = 100%)percentage of free probe). The ... suppression.Moreover, phosphorylation of the RS motif modulates the ability of the N protein to form SGs.RS motif deletion induces the N protein to form large RNP complexes The SARS-CoV N protein might ... SRPK1.Phosphorylation of multiple serines within the RS motif The RS motif of the SARS-CoV N protein is divergentfrom that of canonical SR proteins and contains fewerRS dipeptides. To determine which serines...
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Báo cáo khoa học: H NMR study of the molecular structure and magnetic properties of the active site for the cyanomet complex of O2-avid hemoglobin from the trematode Paramphistomum epiclitum pdf
... between the projection of the tilt of the z axis on the xÂ,y plane (dened direction of tilt of z and the x axis), and j % a + c denes the location of the rhombic (x, y) axes. The orientation of the ... consistent with the % 10° tilt of the Fe-CN vector from the heme normal to avoid van der waalsoverlap with the Tyr32(B10) Og. The location of the rhombic axes, j % 50 ± 10°,isinagreementwiththeexpectations ... [16,17], and the detailed structures provide import-ant information on the novel Hb. The Tyr66(E7) ring isoriented out of the heme pocket in both forms with the Tyr32(B10) in one of the structures...
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Báo cáo khoa học: Structure of the exceptionally large nonrepetitive carbohydrate backbone of the lipopolysaccharide of Pectinatus frisingensis strain VTT E-82164 doc
... in 7b compared with 7a (Table 1) because of the b-effect of the acetylation. Acetylation of 7b was confirmed byESI MS data, which gave the expected mass of 3221.4 Da. The spectra of oligosaccharide ... and showed, in particular, the configuration of ManNAc to beD.From the combined the data on the structures of the isolated oligosaccharides, the overall structure of the P. frisingensis LPS carbohydrate ... methylation. The mostimportant result obtained from NMR analysis of com-pound 4 was the determination of the anomeric configur-ation of Kdo D (see above).Mild acid hydrolysis of the LPS with subsequent...
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Báo cáo khoa học: Determination of the redox potentials and electron transfer properties of the FAD- and FMN-binding domains of the human oxidoreductase NR1 doc
... mixing the human CPR FMN domain with its FAD/NADPH domain(% 16-fold) (29). However, the domain mixture still recon-stituted only % 2% of the activity of the full length CPR. InthecaseofNR1,thekcatfor ... the reconstituted activity is % 3% of that in full length NR1,similartotheratioachievedwithCPRdomains.To explore further the influence of the hydride transferstep on catalytic activity of the ... todetermine the midpoint reduction potentials for the fourredox couples of NR1 (Fig. 9). These data indicate that the relative potentials of the flavins are ordered similarly toTable 2. Summary of observed...
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Báo cáo khoa học: Structure of the O-polysaccharide fromProteus myxofaciens Classification of the bacterium into a newProteusO-serogroup pptx
... LPS)[5,6]. The serological specificity of the bacteria is definedby the structure of the O-specific polysaccharide chain(O-antigen) of the lipopolysaccharide. On the basis of the O-antigens, the strains ... the structure of the O-polysaccharide of P. myxofaciens and serological pro-perties of the LPS of this strain, including cross-reactivity with several other Proteus and Providencia strains with Correspondence ... the Dconfiguration (the b effect on C3 of L-GlcAwouldbeclosetozero[27]).On the basis of the data obtained, it was concluded that the repeating unit of the O-polysaccharide of P. myxofac-iens has the following...
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Báo cáo khoa học: Expression and characterization of soluble forms of the extracellular domains of the b, c and e subunits of the human muscle acetylcholine receptor pot
... amounts of the ECDs of the non-a sub-units of human muscle AChR for use as starting material for the determin-ation of the 3D structure of the receptor ECDs and for the characterization of the ... to verify the identity of the inserts.Yeast transformation and dot-blot screening of positive clonesPlasmids (10 lg) encoding the b1–221 ECD (with or with- out the FLAG epitope) and the various ... con-tains the major part of the binding site for the cho-linergic ligands. The two sites are nonequivalent, onebeing formed at the interface between one a subunitand the c ⁄ e subunits and the other...
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Báo cáo khoa học: Role of the N- and C-terminal regions of the PufX protein in the structural organization of the photosynthetic core complex of Rhodobacter sphaeroides pptx
... in the light of our results. The presence in vitro of a less stabledimer in the mutant PufXD2)7neither affects the photo-synthetic capability of the bacteria nor the efficiency of exchange of ... ability f or photosynthetic growth, the insertion of PufX in the core LH1–RC complex, the stability of the dimers and the kinetics of flash-induced reduction of cytochrome b561 of the cytochrome bc1complex. ... an inhibitory effecton the formation of the LH1 complex. This result suggeststhat the central core of the PufX protein is responsible of the break in the continuity of the LH1 ring in vivo [14],...
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Review of the Literature Regarding Critical Information Needs of the American Public
... surrounding the questions of if and how local community information needs are being served and whether any barriers exist to the fulfillment of these information needs. Clearly then, policy-relevant ... down into the complexities surrounding the questions of if and how local community information needs are being served and whether any barriers exist to the fulfillment of these information ... account of the increasing failure of the news ecosystem to adequately report on education nationally and locally, with some suggestions for the formation of a non-profit reporting sector. The third,...
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Báo cáo sinh học: " Viroporin potential of the lentivirus lytic peptide (LLP) domains of the HIV-1 gp41 protein" docx
... could have the effect of stabi-lizing the Env trimers and/or the resulting transmembranepore that could then be formed by the LLP-1 and -2domains. The location of the LLP-3 domain on the innerleaflet ... http://www.virologyj.com/content/4/1/123Page 9 of 14(page number not for citation purposes)Proposed models of the C-terminus of TMFigure 5Proposed models of the C-terminus of TM. Proposed models of LLP domains in the context of TM ... association with the inner leaflet of the lipid bilayer. On the other hand, the LLP domains maypossess different activities in the different cell types that itinfects, or there may be some as of yet...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam nội dung cụ thể cho từng kĩ năng ở từng cấp độ phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy chỉ tiêu chất lượng 9 tr 25