... diagnosis of the synchronous described malignancies Neuroendocrine tumors fromanunknownprimarysite are uncommon; they arise froman occult or clinically undetectable primarysite in one of several ... panel is synaptophysin, chromogranin and neural cell adhesion molecules (CD56) [11] The association of basal cellcarcinoma and neuroendocrine carcinomaof the skin, also called Merkel cellcarcinoma ... neuroendocrine carcinomafromanunknownprimary site: A case report and review of the literature Journal of Medical Case Reports 2011 5:462 Authors’ contributions MM was involved in the analysis of the...
... clinical course of our case, with the appearance ofcervicallymphnodemetastases after four years of follow-up, supports the approach of Goode and Corio [10] The prognosis of oncocytic carcinomas ... number of studies have reported multiple recurrences of this tumor and regional or distant metastases [2,6,8-10] The cervicallymph nodes may be affected as with other malignant tumors of the ... mitoses and cellular pleomorphism with extensive invasion and destruction of adjacent structures [6] This tumor is predominantly composed of round or polyhedral cells arranged in small clusters and...
... ofsquamouscellcarcinoma Microscopic examination ofsquamouscellcarcinoma A) Esophagus infiltrative squamouscellcarcinoma (H and E 10×); B) Esophagus infiltrative squamouscellcarcinoma ... immunohistochemistry of the fused cells showed an intense and diffuse positivity for CD117, CD34 and CD99 and negative results for S100, desmin and actin (Figure 3A, B) The proliferate index Ki 67 was less than ... regions such as the large intestine, rectum, and omentum and with an incidence of less than 5% in the esophagus [4] A The median age of onset is 60–69 years and the symptoms are usually non-specific...
... tumors at multiple sites One patient had a history ofan esophagus carcinoma, a basal cell carcinoma, and a melanoma; another one suffered from a prostate and a bladder carcinoma, and one patient ... development ofsquamouscellcarcinomaof the head and neck (SCCHN) Journal of Negative Results in BioMedicine 2010 9:10 Submit your next manuscript to BioMed Central and take full advantage of: • ... frequency in squamouscell carcinomas of the head and neck underestimated? Analysis of p53 exons 2-11 and human papillomavirus 16/18 E6 transcripts in 123 unselected tumor specimens Cancer Res 2003,...
... tumor located at the posterior wall and the dome of the urinary bladder (another site than described for the squamouscell carcinoma) As an initial attempt at transurethral resection (TUR) resulted ... authors thank Prof Dr Wolf F Wieland and PD Dr Maximilian Burger, Department of Urology, University of Regensburg, Germany, for their excellent support References 10 Katchy KC, Ziad F, Alexander ... that the outcome of pPNET of the urinary bladder cannot be predicted On the one hand, this is due to its rarity and thus missing long-term data, and, on the other hand, because it often affects...
... equilibrium and probably triggered the pulmonary metastatic malignant growth of dormant tumor cells from the primary renal carcinoma This supports the importance of immune surveillance as part of tumor-host ... diagnosis of clear cell adenocarcinoma pT2pN0M0 (primary tumor localized in the kidney parenchyma without metastases in the regional lymph nodes and without distant metastases according to "tumour -node- metastasis" ... probable trigger of such expansion Tumor dormancy represents an existence ofan apparent balance between tumor cell elimination and proliferation, or between effective immune surveillance and immune...
... Advanced cutaneous squamouscellcarcinomaof the trunk and extremity: analysis of prognostic factors J Surg Oncol 1997, 64:212-217 Veness MJ: Time to rethink TNM staging in cutaneous SCC Lancet ... M, Gabrielli F, Migliano E, Pagan M, Concolino F, Ruatti P: Lymphatic mapping and sentinel node identification in squamouscellcarcinoma and melanoma of the head and neck Tumori 2002, 88:S39-41 ... excision of perineal squamouscell carcinoma: H&E staining at 2X (A) and 40X (B) Sentinel lymphnode biopsy: H&E at 10X (C) and immunostaining with pancytokeratin at 10X (D) showing no evidence of...
... PJ: SquamousCellCarcinomaof the skin of the trunk and limbs: The incidence ofmetastases and their outcome Aust N Z J Surg 1992, 62:697-701 Ames FC, Hickey RC: Squamouscellcarcinomaof the ... carcinomaof the skin and lip J Am Acad Dermatol 1989, 21:241-248 Vauterin TJ, Veness MJ, Morgan GJ, Poulsen MG, O'Brien CJ: Patterns oflymphnode spread of cutaneous squamouscellcarcinomaof the ... significant factor: of 11 patients with preceding chronic skin lesion at the siteof SCC presented lymphnode metastasis, versus of 35 (p = 0.050) The mean time of presentation oflymphnode metastasis...
... review of duodenal metastasesfromsquamouscellcarcinomaof the cervix presenting as an upper gastrointestinal bleed Rani Kanthan1, Jenna-Lynn Senger1, Dana Diudea1, Selliah Kanthan2 Department of ... more common than primary lesions, and most commonly arise from malignant melanoma, carcinomaof the lung, genitourinary cancers, breast cancer, Kaposi’s sarcoma, colonic and renal cell carcinomas ... Bowel MetastasesfromSquamousCellCarcinomaof the Cervix as Reported in the Literature (PubMed and Medline available since 1981) – search terms: squamouscellcarcinoma AND “cervix”/”carcinoma...
... The impact ofsquamouscellcarcinoma (SCC) antigen in patients with advanced cancer of uterine cervix treated with (chemo-)radiotherapy Anticancer Res 2005, 25:1663-1666 Page of 15 Ngan HY, Cheng ... Serum squamouscellcarcinoma antigen and CYFRA 21-1 in cervical cancer treatment Int J Radiat Oncol Biol Phys 2002, 52:23-32 17 Chan YM, Ng TY, Ngan HY, Wong LC: Monitoring of serum squamouscell ... Forni F, Ferrandina G, Deodato F, Macchia G, Morganti AG, Smaniotto D, Luzi S, D’Agostino G, Valentini V, Cellini N, et al: Squamouscellcarcinoma antigen in follow-up ofcervical cancer treated...
... when samples were less than 70% of tumor cells Primary tumor and lymphnode specimens were obtained from all patients by surgical resection ofprimary tumors with lymph nodes dissection according ... standards Consequently, 80 pairs ofprimary tumors and the corresponding lymph nodes metastases were analyzed All samples were from patients of Chinese origin with NSCLC The characteristics of ... database of lung cancer cases undergoing curative resection for excision ofprimary tumor and the corresponding lymph nodes metastases at the Pathology Department of Tianjin Medical University Cancer...
... normal The cervical ultrasound showed multiple cervicallymph nodes which were of different sizes ranging from mm to 17 mm A cervical CT revealed bilateral cervicallymph nodes less than cm in ... suspicion ofcarcinoma [1] Malignant tumors developing from the thyroglossal duct have two origins: thyrogenic carcinoma arising from thyroembrionic remnants in the duct or a cyst, and squamouscellcarcinoma ... CC: Primary papillary carcinomaof a thyroglossal duct cyst: Report of a case and literature review Br J Surg 1991, 78:87-89 Chu YC, Han JY, Han HS, Kim JM, Min SK, Kim YM: Primary papillary carcinoma...
... GH: An analysis of distant metastasesfromsquamouscellcarcinomaof the upper respiratory and digestive tracts Cancer 1977, 40:145-151 Papac RJ: Distant metastasesfrom head and neck cancer Cancer ... in head and neck cancer Int J Radiat Oncol Biol Phys 1998, 42:803-806 El-Sayed S, Nelson N: Adjuvant and adjunctive chemotherapy in the management ofsquamouscellcarcinomaof the head and neck ... incidence of malignant disease II Carcinomaof the lip, oral cavity, larynx and antrum Am J Cancer 1937, 31:238-252 Kowalski LP, Carvalho AL: Natural history of untreated head and neck cancer Eur J Cancer...
... observation of the entire esophagus: 1) disappearance of the tumor lesion; 2) disappearance of ulceration (slough); and 3) absence of cancer cells in biopsy specimens If small nodes of cm or less ... esophageal carcinomas Anticancer Res 2003; 23: 3493-8 Yamada H, Maki H, Takeda Y, et al Evaluation of combined nedaplatin and docetaxel therapy for human head and neck cancer in vivo Anticancer Res ... for T4 and/or M1 lymphnodesquamouscellcarcinomaof the esophagus J Clin Oncol 1999; 17: 2915-21 Kaneko K, Ito H, Konishi K, et al Definitive chemoradiotherapy for patients with malignant stricture...
... of pluripotent embryonic stem and germ cells [11,12] Recent data show that cells expressing high levels of Oct4 are present in breast cancer, bladder cancer and oral squamouscellcarcinoma and ... correlations of Oct-4 and Nanog in oral cancer stem-like cells and high-grade oral squamouscellcarcinoma Clin Cancer Res 2008, 14:4085-4095 Ezeh UI, Turek PJ, Reijo RA, Clark AT: Human embryonic stem cell ... significance of Oct4 and Sox2 expression in hypopharyngeal squamouscellcarcinoma Journal of Translational Medicine 2010 8:94 Page of Submit your next manuscript to BioMed Central and take full advantage...
... treatment for head and neck squamous- cell carcinoma: three meta-analyses of updated individual data MACH-NC Collaborative Group Meta-Analysis of Chemotherapy on Head and Neck Cancer Lancet 2000, 355:949-955 ... The primary tumor site was also heterogeneous, and the prognosis of HNSCC is dependent on the primary tumor site In our study, those oral cavity cancer had the worst prognosis and laryngeal cancer ... Sources of support: Chang Gung Memorial Hospital Grant (CMRPG890471 to Yi-Ju Chen, CMRPG890921 to Chang-Han Chen and CLRPG871342 to Samuel HH Chan) Author details Department of Medical Oncology, Chang...
... grade Material and methods Cell lines and human oesophageal specimens This study used three human oesophageal squamouscellcarcinomacell lines and an oesophageal adenocarcinoma cell line Moderate-differentiated ... oesophageal squamouscellcarcinoma cells, but expressed in other three types of oesophageal cancer cell lines (B) Verification of over-expression and knockdown of MTSS1 in the oesophageal cancer cell ... expression in oesophageal cancer cell lines and over-expression and knockdown of MTSS1 (A) RT-PCR analysis of MTSS1 mRNA expression within a panel of oesophageal cancer cell lines MTSS1 was not...
... breast cancers, with scores of 0,+1, +2, +3 for increasing intensity and “continuity” of staining of the cell membrane[17] For quantification of Her3 staining, we scored two compartments of the cell ... Her3, using cut-offs of greater than or equal to +1 (range to +3)for membranous staining of Her2 and Her3, and greater than or equal to (range to 12) for cytoplasmic expression of Her3 Her2 gene ... that of the three cell lines tested, MCF7 cells had high levels of Her3, BxPC3 cells had intermediate Her3, and A549 cells had low Her3 (Figure 1) We analyzed the expression pattern of Her2 and...
... treatment for head and neck squamous- cell carcinoma: three meta-analyses of updated individual data MACH-NC Collaborative Group Meta-Analysis of Chemotherapy on Head and Neck Cancer Lancet 2000, 355:949-955 ... The primary tumor site was also heterogeneous, and the prognosis of HNSCC is dependent on the primary tumor site In our study, those oral cavity cancer had the worst prognosis and laryngeal cancer ... Sources of support: Chang Gung Memorial Hospital Grant (CMRPG890471 to Yi-Ju Chen, CMRPG890921 to Chang-Han Chen and CLRPG871342 to Samuel HH Chan) Author details Department of Medical Oncology, Chang...
... grade Material and methods Cell lines and human oesophageal specimens This study used three human oesophageal squamouscellcarcinomacell lines and an oesophageal adenocarcinoma cell line Moderate-differentiated ... oesophageal squamouscellcarcinoma cells, but expressed in other three types of oesophageal cancer cell lines (B) Verification of over-expression and knockdown of MTSS1 in the oesophageal cancer cell ... expression in oesophageal cancer cell lines and over-expression and knockdown of MTSS1 (A) RT-PCR analysis of MTSS1 mRNA expression within a panel of oesophageal cancer cell lines MTSS1 was not...