các yếu tố ảnh hưởng đến tiêu hao nl trong vận cơ
Targeted delivery of doxorubicin conjugated to folic acid and vitamin e d a tocopheryl polyethylene glycol succinate (TPGS
... special thanks to my friends Ms Anitha Paneerselvan and Mr Gan Chee Wee, from our group for having enlightened my knowledge by thoughtful discussions and timely help I would also like to thank the ... Biodistribution………………………………………………… 113 5.4 Conclusions…………………………………………………………………………118 CHAPTER 6: CONLCUSIONS AND RECOMMENDATIONS………………………………119 6.1 Conclusions…………………………………………………………………………119 6.2 ... drug and the polymer in destroying the cancer cells The rationale for polymer conjugation is to mainly prolong the half-life of therapeutically active agents by increasing their hydrodynamic volume...
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báo cáo khoa học: "Control of prostate cancer associated with withdrawal of a supplement containing folic acid, L-methyltetrahydrofolate and vitamin B12: a case report" pps
... 2011, 5:413 http://www.jmedicalcasereports.com/content/5/1/413 overall survival Two years later Heinle and Welch [2] reported FA stimulation of chronic myelogenous leukemia (CML) in three patients ... effective or unsuccessful The patient was restaged, with a bone scan and computed tomography yielding only evidence of biochemical PSA relapse He then received docetaxel 30 mg/m2 for three of every four ... ingesting a multivitamin such as Centrum Silver (Pfizer Consumer Healthcare, Madison, NJ USA) is commonly associated with hypervitaminosis of FA to levels demonstrated to be associated with unnatural...
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Báo cáo y học: "A folate-rich diet is as effective as folic acid from supplements in decreasing plasma homocysteine concentrations"
... capsule daily for five weeks, followed by a five-week “washout” period during which they consumed only their usual diet After this period, they were switched to the alternate treatment for another...
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Báo cáo y học: "The primary prevention of birth defects: Multivitamins or folic acid"
... of information Three groups were differentiated: (i) data only from the antenatal care logbook and/or other medical records; (ii) data only from the questionnaire; and (iii) concordant data from ... have only a preventable fraction by folic acid For all CAs the risk reduction associated with periconceptional multivitamin supplementation was 47% in the Hungarian RCT [2-5] while it was only ... the analysis: folic acid alone and folic acid plus other medicines The route of administration Only tablet for oral use was marketing The dose In Hungary, folic acid was available as a mg tablet...
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Báo cáo y học: Esterified Hyaluronic Acid and Autologous Bone in the Surgical Correction of the Infra-Bone Defects"
... periodontal disease [24,25] HA can be an ideal vector for the bone morphogenic proteins (BMP), the only growth factors universally recognized to be able to stimulate the formation of new bone tissue ... Austen L, Moore D, Hoare K ras-Trasformed cells express both CD44 and RHAMM hyaluronan receptors: only RHAMM is essential for hyaluronan promoted locomotion Exp Cell Res 1993;207:277-82 Heldin P,...
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THÀNH PHẦN hợp CHẤT AXÍT béo và CAROTENOID của gấc fatty acid and carotenoid composition of gac (momordica cochinchinensisspreng) fruit
... comparing to known, published spectra of carotenoids to identify these compounds, which are found commonly in fruit such as tomato, guava, and citrus RESULTS AND DISCUSSION Weight Distribution of Fruit ... palmitic acid contributed 5.6% (range, 5.2-6.2), while eicosa-113-enoic acid was found at 3.0%, but only in one fruit Small amounts of arachidic, cis- gac mesocarpb trans lycopene SDc RSDd cis-lycopene ... to have significant amounts of Vitamin E and omega-3 fatty acids (21), although our data show only 0.3-0.8% linolenic acid (Table 2) Seeds of tropical plants may contain high levels of saturated...
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Tài liệu Báo cáo khoa học: Marine toxins and the cytoskeleton: okadaic acid and dinophysistoxins pptx
... activate protein kinase C in vitro They have potent tumor-promoting activities on mouse skin, as strong as those of TPA-type tumor promoters It is well known that transformation of cells requires ... cytoskeletal dynamics and organization Although there have been numerous studies employing DSPs, and mainly OA, to examine the role of protein phosphatases in cytoskeletal dynamics and cytoskeletal organization, ... purpose, DSP toxins have been widely employed, with OA being one of the most useful tools As the only known targets for OA are Ser ⁄ Thr protein phosphatases, its toxic effects have been usually...
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Tài liệu Báo cáo Y học: The b-1,4-endogalactanase A gene from Aspergillus niger is specifically induced on arabinose and galacturonic acid and plays an important role in the degradation of pectic hairy regions pdf
... only D-galactotriose, D-galactotetraose and D-galactopentaose were detected but also L-arabinose substituted forms of these three oligosaccharides (Fig 6) After prolonged incubations (2 h), only ... pectin [1], whereas the others served as controls Expression of galA in the wild type strain was only detected in the presence of D-galacturonic acid (Fig 3) However, in the CREA mutant expression ... transferred for h to minimal medium containing carbon sources as indicated in Fig Expression of galA was only detected in the presence of sugar beet pectin, whereas expression of lacA was detected in the...
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Tài liệu Folic acid gia tăng chức vụ của màng trong mạch máu và giảm huyết áp những người hút thuốc lá: một thử nghiệm mới pptx
... nghiện thuốc Từ lâu, nhận thấy đợc tác dụng che chở tim mạch folic acid có thể, sinh tố B ngời có nhiều yếu tố nguy hiểm tim mạch nh bệnh nhân có nồng độ cao homocysteine, cholesterol bị đứng ... folic acid có ảnh hởng rõ rệt bệnh nh tiểu đờng, cao huyết áp, đứt động mạch não có lợng homocysteine cao hay cao máu Đây thử nghiệm với số bệnh nhân nhỏ mục tiêu thử nghiệm không đặt tiêu chuẩn ... ta đo khoảng cách mạch máu cổ (carotid) mạch máu đùi Sau dùng máy Conplior đo sóng máu lu thông, sóng đợc truyền vào computer tính đợc PWV Ngời ta đo 20 lần liên tiếp lần đối tợng đến thăm viếng...
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Báo cáo khoa học: Reconstruction ofde novopathway for synthesis of UDP-glucuronic acid and UDP-xylose from intrinsic UDP-glucose inSaccharomyces cerevisiae pptx
... W303a, TOY1 and TOY3 cells The assay revealed that UDP-GlcA was present only in the cells of strain TOY1, whereas UDP-Xyl was only present in the cells of strain TOY3, consistent with the idea that ... transmembrane region and is a soluble protein localized to the cytoplasm [17,18] In mammalian cells, only the membrane-type UXS enzyme has been identified [4] The reason for the existence of multiple ... 578.6) were detected in TOY1 cells (Fig 3A) As TOY3 carries both enzymes, we expected that not only UDP-Glc but also UDP-GlcA and UDP-Xyl would be present in these cells As expected, both UDP-Glc...
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Báo cáo khóa học: Characterization of Mesorhizobium huakuii lipid A containing both D-galacturonic acid and phosphate residues ppt
... of crude lipid A preparation obtained from M huakuii IFO 15243T LPS revealed the presence not only of 2,3-diamino-2,3-dideoxyglucose (DAG) and a complex set of fatty acids (both ester and amide ... chain fatty acids These are ester-linked to the lipid A The second group of fatty acids needs strong liberation conditions [32] This group comprises all 3-hydroxyl and 4-oxo fatty acids, which ... and 3-OH-20:0 clearly predominated The types of ester-bound fatty acids were also numerous, but only four of them, namely i-17:0, 20:0, 22:1 and particularly 27-OH-28:0 fatty acid, predominated...
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Báo cáo Y học: Concerted regulation of free arachidonic acid and hormone-induced steroid synthesis by acyl-CoA thioesterases and acyl-CoA synthetases in adrenal cells pdf
... thioesterase activity Although NDGA is commonly used as an inhibitor of the lipoxygenase pathway, it is also known to inhibit PLA2 activity [27] Since NDGA strongly inhibited both steroid production ... effect on steroid production suggests this is unlikely This, along with the fact that 22R-OH-cholesterol by-passes the effect of the inhibitors strongly indicates that the thioesterase and the ... of recombinant protein with NDGA inhibited thioesterase activity Interestingly, NDGA produced only a 20% inhibition of the mitochondrial enzyme activity when measured in mitochondria isolated...
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Báo cáo Y học: A polymer with a backbone of 3-deoxy-D-glycero -D-galacto -non-2ulopyranosonic acid, a teichuronic acid, and a b-glucosylated ribitol teichoic acid in the cell wall of plant pathogenic Streptomyces sp. VKM Ac-2124 pdf
... et al [14] The microtubers were immersed for 5–10 in a suspension of 14-day-old agar culture (mainly, spore mass) grown on Czapek’s agar [6] followed by incubation at 100% relative humidity for...
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Báo cáo khoa học: Polysaccharide binding sites in hyaluronate lyase – crystal structures of native phage–encoded hyaluronate lyase and its complexes with ascorbic acid and lactose docx
... opposed to the bacterial lyases, however, the phage hyaluronidase recognizes hyaluronan as its only substrate [7] The bound hyaluronidase produced by the bacteriophage is not secreted from the ... almost at the same regions of the concave substrate binding sites (Fig 4) In the case of position only, ascorbic acid binds at a position that is approxi˚ mately A away from that of lactose binding ... protein ⁄ water atoms This is one of the most firmly held ascorbic acid molecules, indicating the strong nature of the binding of ascorbic acid to proteins Although ascorbic acid is a small molecule,...
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Báo cáo khoa học: Salicylic acid and the hypersensitive response initiate distinct signal transduction pathways in tobacco that converge on the as-1-like element of the PR-1a promoter pot
... infected plants exhibiting the HR TMV infection of transformants 313–6 and 313–7 produced only 2.7- to 4.8fold stronger GUS activities than chemical treatment (Fig 4A) To account for possible errors ... report that the level of SA inducible gene expression is controlled by the as-1-like element in the strong )1533 bp PR-1a promoter from tobacco To further analyze the functional significance of as-1-like ... complementary to the 5¢ end of the reporter gene PCR products were cut with HpaI which cleaves only in the as-1 containing promoter regions, but not in the PR-1a wild-type promoter Reaction products...
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Báo cáo khoa học: Redox reaction between amino-(3,4-dihydroxyphenyl)methyl phosphonic acid and dopaquinone is responsible for the apparent inhibitory effect on tyrosinase doc
... monitored by oxygen consumption, a substantial drop in oxygen concentration was also registered only for the diphenolic derivative (compound 1) To identify the oxidation product(s) we originally ... 0.1 and 0.5 mM concentration in reactions with tyrosinase After h, the aldehyde was detectable only in the reaction Ó FEBS 2002 Oxidation of phosphonic 3,4-dihydroxyphenylglycine (Eur J Biochem ... tyrosinase was competitive in nature However, Km equal 0.52 ± 0.10 mM indicated that this was rather unlikely (Km for Dopa under our conditions was 0.37 ± 0.08 mM) We have not observed a decrease in...
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Separation of acetic acid and water by distillation effect of calcium chloride addition
... acetic acid, it was possible to go to as high as 60 weight % salt in the wateriich region but only t o about 30 weight % in the acid-rich range For any particular run, the acetic acid-water 100 ... content with 20 silver nitrate, using sodium chromate as the indicator (Mohr's method) (6) It was only necessary, prior to this second titration, t dis: charge the caustic-phenolphthalein end point ... molecular weight of the cellulose acetate, increased the effect He observed the salt effect mainly Kith calcium chloride and found that it increased with the amount of salt added An especially...
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báo cáo hóa học:" Implantation of neural stem cells embedded in hyaluronic acid and collagen composite conduit promotes regeneration in a rabbit facial nerve injury model" doc
... which were in contrast to the predominance of connective tissues and apparent angiogenesis in a chaotic manner in rabbits without management of nerve fiber truncation (data not shown) A lesser ... conduit of high surface area and porosity for cell adhesion and guide for the nerve fibers [26] Not only it is requisite to nerve regeneration, but also it is vital to accommodate effecter molecules ... vivo In the study the supplement of NT-3 to NSCs embedded in HA-collagen composite scaffold not only enhanced NSCs differentiation and neurite outgrowth, but also provided growth factor to promote...
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báo cáo hóa học: " Folic acid use in pregnant patients presenting to the emergency department" pptx
... represent folic acid use among the full spectrum of pregnant ED patients Similarly, our study focused only on those patients who presented to the ED with pregnancy-related symptoms Ideally, folic acid ... National Health and Nutrition Examination Survey, 2001-2002 Am J Clin Nutr 2007, 85(5):1409-16 Quinlivan EP, Gregory JF: Effect of food fortification on folic acid intake in the United States Am...
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CHAPTER 4: THE CITRIC ACID AND OXIDATIVE PHOSPHORYLATION ppt
... monosaccharide glucose is a sixcarbon sugar In the case of higher eukaryotes, a cell most commonly acquires glucose in two ways—by breaking down complex carbohydrates into simple sugars and by ... reaction cycle, including one GDP, one inorganic phosphate, three NAD+, and one ubiquinone, commonly referred to as, Q 33 REACTANTS AND PRODUCTS Products that emerge from one turn of the citric...
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