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Báo cáo y học: "Out of the sequencer and into the wiki as we face new challenges in genome informatics" doc
... Marcin Piechota (Institute of Pharmacology, Krakow, Poland) described genes2mind.org, an online resource for the genomic profiling of psychoactive drugs The database contains comparisons of the ... science The growth of sequencing data is far outpacing the rate of curation Previously successful models are not meeting the demands of genome biology and, in many historical cases, the majority of ... copy number variants and transcript diversity Chromatin immunoprecipitation sequencing (ChIPSeq) provides an extraordinary window into the dynamics of protein-DNA binding Xin Feng (Stony Brook...
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báo cáo khoa học: " Changes in time-use and drug use by young adults in poor neighbourhoods of Greater Buenos Aires, Argentina, after the political transitions of 2001-2002: Results of a survey" potx
... responded that, in both 2001 and 2004, they spent “zero hours” in these activities: changes in time of drug use; work; looking for work; and hanging out in the neighbourhood In the case of the variable ... number of substances they used and their routes of administration These included the age of first use, and data on frequency of use “ever” and for last months, for: cannabis, intranasal cocaine, ... from office in less than two months During the 1980s and 1990s, Argentina struggled with high inflation and industrial stagnation that peaked in the 1990s [9] By the end of 2001, a large number of...
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Báo cáo khoa học: Photodynamic treatment and H2O2-induced oxidative stress result in different patterns of cellular protein oxidation ppt
... determine the sites of the oxidative modifications within the tubulin molecule, and to elucidate the role of these modifications in the functional damage to tubulin Interestingly, for the two modes of ... patterns of protein labeling were distinctly different (Fig 4A,B) Matching the blot with the protein map shows that PDT caused labeling of a-tubulin and b-tubulin (spots and 2) The minor spot ... crosslinking of proteins Kinetics of the FMN- 24 25 26 27 28 29 30 31 32 33 34 35 36 and rose bengal-sensitized photooxidation and intermolecular crosslinking of model tyrosine-containing N-(2-hydroxypropyl)...
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báo cáo hóa học:" Concordane of OSTA and lumbar spine BMD by DXA in identifying risk of osteoporosis" pptx
... shows the different cutoffs for LS BMD T score by DXA and the categories of low, moderate, and high risk of osteoporosis by OSTA index Table was the fourfold table of OSTA in assessing risk of osteoporosis ... weight, nutritional status, history of fracture, childbearing, and so on[15] We think there were limitations in OSTA risk index by using only age and weight According to the OSTA formula, if the ... according to the OSTA index is shown in Figure On the basis of categories used in Asian women[4], there are 50.5% women (n = 110) of low risk, 42.2% (n = 92) of moderate risk, and 7.3% (n = 16) of...
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báo cáo hóa học:" Activation of PKA, p38 MAPK and ERK1/2 by gonadotropins in cumulus cells is critical for induction of EGF-like factor and TACE/ ADAM17 gene expression during in vitro maturation of porcine COCs" doc
... maturation of oocyte It has been reported that during the ovulation process the PKA-dependent pathway involving the ligand activation of G protein-coupled receptors by their ligands in cumulus and/ or ... Competing interests The authors declare that they have no competing interests Authors' contributions YY and MS conceived of the study, participated in its design and coordination and drafted the ... resulting from the addition of U0126 was not overcome by the addition of EGF, the addition of EGF to H89- or SB203580-containning medium overcame the negative effect of each inhibitor on these...
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Báo cáo toán học: "OXIDATIVE PHOSPHORYLATION: Kinetic and Thermodynamic Correlation between Electron Flow, Proton Translocation, Oxygen Consumption and ATP Synthesis under Close to In Vivo Concentrations of Oxygen" docx
... Fourth, to 10 μl of standard medium containing from to 400 nmols of ADP were added into the cell and the system again incubated until the O2 and ATP (contaminating the sample of ADP) added Oxygen ... O2 and protein Thus, when the concentration of protein is increased maintaining constant the concentration of O2, the energy directly involved in the synthesis of ATP is substantially reduced Indeed, ... measuring the steepest portion of the traces Each unit represents μmole in the presence of cytochrome c and 3.57 μmole in the presence of NADH In Fig 4c the extent of ATP synthesis was determined in...
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Báo cáo lâm nghiệp: "Variations in seed and seedling responses to water stress in three provenances of Eucalyptus camaldulensis Dehnh" pptx
... reduced leaf area most in Katherine seedlings (Fig 4), and the provenances also differed in stress-induced changes in the partitioning of dry matter into roots, stems and leaves (Fig 5) Stressed ... between provenances in the production of hairs on the collar of germinating seedlings (Fig 1which bind the III to the soil and assist early uptake Shoot growth of Petford seedlings was best at high ... Creek and Katherine and, in several instances, it appeared the most adaptable provenance It occurs naturally on well-drained, sandy, infertile soils and is developing a reputation as an outstandingly...
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Báo cáo y học: " Rates and risks for prolonged grief disorder in a sample of orphaned and widowed genocide survivors" potx
... participated in the design, the coordination and the assessments of the study JPD participated in the design and the coordination of the study TE participated in the design of the study and contributed ... contributed to the interpretation of findings and writing of the paper All authors read and approved the final version Competing interests The authors declare that they have no competing interests ... and N.J.) in the basic theoretical concepts and in sensitive and empathic interviewing techniques The first interviews in the field were conducted under the supervision of the psychologists and...
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Báo cáo khoa học: " Early decompressive craniectomy and duraplasty for refractory intracranial hypertension in children: results of a pilot study" ppsx
... of traumatic hematomas and other space occupying lesions, prevention of secondary brain injury is the mainstay of intensive care treatment in pediatric severe head injury Diffuse brain swelling ... space occupying intracranial lesions [10] Continuing and sustained deviation of the ICP > 20 mmHg for longer than 30 was treated by single doses of barbiturate (2–5 mg/kg) and by infusion of mannitol ... all patients received catecholamines (epinephrine and norepinephrine) as needed Intensified treatment protocol Standard therapy was intensified in cases of an ICP increase > 20 mmHg for at least...
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Báo cáo y học: "Association between inflammatory mediators and response to inhaled nitric oxide in a model of endotoxin-induced lung injury" docx
... (metabolite of prostacycline) The levels of the proinflammatory cytokine IL-8 followed the endotoxin evolution in blood Endothelin-1 and inhaled nitric oxide The ET-1 in plasma rose rapidly and markedly ... analysis ML was involved in the study design and in revising the manuscript GH has made a substantial contribution to the design and conception of the study, and to the interpretation of data Acknowledgements ... hour after onset of endotoxin infusion) and on endotoxin exposure, and remained low until the end of the experiment (T4 to T6) Initially the neutrophils decreased as a fraction of the total leukocyte...
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Báo cáo y học: "Tandem and cryptic amino acid repeats accumulate in disordered regions of proteins" ppt
... repeats the proportions of repeats lying within domains were Tables and list the identifiable InterPro domains most commonly containing each of the main tandem and C4 repeat types Of the tandem ... of proteins that might have a number of functions, including binding to other proteins and small molecules and providing flexibility in multidomain proteins In an analysis of repeat content of ... length of 10, on average 85% of proteins contained a predicted IUR Twenty to 21% of mammalian proteins and 13% of chicken proteins contained some kind of tandem AAR and 12% of mammalian proteins and...
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An Overview into the Semantic of Questions in English and Vietnamese
... request for information The semantics refers to the close and intense relationship between the form and the meaning of a sentence (Thiêm, 2004) Comparing and contrasting questions in terms of their ... không…? Interestingly, in Vietnamese, to emphasis a confirmation, we can reverse the position of the tag to the beginning of the question (Thiêm, 2004) The tags can be put at the beginning or ... thông? On the other hand, in English, a rising intonation is important when using tag questions In fact, rising intonation is the only feature that makes this type of questions distinct from...
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AN INVESTIGATION INTO THE SENTENCE PATTERNS USED IN TRAVEL ADVERTISEMENTS ON ENGLISH AND VIETNAMESE WEBSITES
... Advertising is the activity of individuals or organizations of manufacturing and services, using modes and means of communications to inform the publics about their demands and ability or the benefits ... from the clause without affecting its acceptability and without affecting the relations of structure and meaning in the rest of the clause E.g.: She kindly sent them a warm greeting A_optional In ... description of advertising, helping give out types of advertising as in the following 1.2.1.2 Types of advertising According to Leech (1972), most frequent and important type of the advertising is...
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Tài liệu University Oars Being a Critical Enquiry Into the After Health of the Men Who Rowed in the Oxford and Cambridge Boat-Race, from the Year 1829 to 1869, Based on the Personal Experience of the Rowers Themselves pdf
... emigrated, and were either residing in our Colonies or in other parts of the world, and the only method I could discover of obtaining information regarding several of viil INTRODUCTION them, was ... captain of the John +, a boat which has often played a prominent part in the struggles of the Isis, and which has served as the training-school for no fewer than ten of the Crews which during the ... can in no possible way be traced to the effects of rowing, we come to the consideration of those diseases of the respiratory and the circulatory systems (in other words of the lungs and of the...
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Tài liệu Báo cáo Y học: A Raman optical activity study of rheomorphism in caseins, synucleins and tau New insight into the structure and behaviour of natively unfolded proteins pot
... structure relies mainly on the evidence outlined above In view of the close similarity of the ROA spectra of the casein, synuclein and tau proteins shown in this paper, we have reproduced in Fig from ... that the former is likely to be in the Cterminal half and the latter in the N-terminal half of the protein [29,48±51] Sequence-based structure prediction methods suggest that the caseins are of the ... form of b strand [18] The positive bands at » 1675 cm)1 in the amide I region of the ROA spectra of b- and j-casein, which originate mainly in the peptide C O stretch, are characteristic of disordered...
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Báo cáo khoa học: Protein transport in organelles: Protein transport into and across the thylakoid membrane pptx
... immediate vicinity of the twin arginine motif, whereas Hcf106 cross-links less strongly to residues in the hydrophobic core and the early mature protein [32] Binding of the precursor can occur in the ... membranes The transported protein is released from the translocase into the lipid bilayer, where the signal peptide is removed by the TPP and the mature protein is released into the lumen After protein ... region ending in an Ala-X-Ala terminal processing site Proteins destined to be transported by the Tat pathway contain a characteristic pair of arginine residues in the N-terminal region of the signal...
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Báo cáo khoa học: Insertion of the plant photosystem I subunit G into the thylakoid membrane In vitro and in vivo studies of wild-type and tagged versions of the protein doc
... 386 and 387, or at the extreme C-terminus of PSI-G (Fig 1) These cassettes were both cloned into binary vectors under the control of the 35S promoter and terminator, and into vectors for in vitro ... harvesting complex (LHCI), consisting of four members (Lhca1–4) of the chlorophyll a ⁄ b binding protein family LHCI is bound along one side of PSI only, in the vicinity of the PSI-F and PSI-J ... Incorporation of tagged PSI-G into PSI Whilst it is evident that both C-terminally and looptagged PSI-G can insert into the thylakoid in vivo (Figs and 5), it is possible that the tags hinder assembly into...
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Báo cáo Y học: The mechanism of nitrogen monoxide (NO)-mediated iron mobilization from cells NO intercepts iron before incorporation into ferritin and indirectly mobilizes iron from ferritin in a glutathione-dependent manner pot
... using the GSH synthesis inhibitor, BSO (0.1 mM) This latter agent is a potent and selective inhibitor of the enzyme c-glutamylcysteine synthetase that is involved in GSH synthesis [40] A 20-h incubation ... performed Examining the intracellular distribution of 59Fe in control cells, ferritin-59Fe increased as a function of reincubation time (Fig 3B) In fact, after a reincubation time of 240 in control ... within cells [23,30] Further, Rogers and Ding [48] have shown that L-cysteine is necessary for the removal of dinitrosyl–Fe complexes from [Fe–S]-containing proteins in Escherichia coli Interestingly,...
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Báo cáo khoa học: Protection of chylomicron remnants from oxidation by incorporation of probucol into the particles enhances their uptake by human macrophages and increases lipid accumulation in the cells ppt
... differentiate into macrophages by incubation for 72 h in the presence of PMA (200 ngÆmL)1) Then, cells adhering to the culture plates, and the medium containing the PMA and any remaining monocytes, ... antioxidants, are absorbed in the intestine and secreted into lymph in chylomicrons, large triacylglycerol-rich lipoproteins which pass into the blood via the thoracic duct and are then rapidly metabolized ... Effect of pCRLPs on lipid synthesis in THP-1 macrophages The effects of CRLPs and pCRLPs on lipid synthesis in THP-1 macrophages were investigated by measuring the incorporation of [3H]oleate into...
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Báo cáo khoa học: Characterization of a membrane-bound angiotensin-converting enzyme isoform in crayfish testis and evidence for its release into the seminal fluid ppt
... the lung, myocardium, liver, intestine and testis, as well as in the epithelial cells of the kidney and intestine [3] Its role in the regulation of the renin– angiotensin–aldosterone system has ... section of vas deferens, staining is strong in the seminal fluid (sf), with weak staining also being present in the spermatozoid membranes (spz) The walls (w) of the vas deferens are not stained ... in spermatozoid metabolism Indeed, during mating, the male crayfish deposits sperm near the openings of the female gonoducts (i.e at the base of the third periopods), using the two first pair of...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc các đặc tính của động cơ điện không đồng bộ đặc tuyến hiệu suất h fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008