... of NG2 in multiple cell types during the processes of demyelination and remyelination Following microinjection of L-a-lysolecithin into thespinalcord white matter, we have investigated the activation, ... mouse spinalcord J Cell Sci 1972, 10:535-546 37 Blakemore WF, Eames RA, Smith KJ, McDonald WI: Remyelination inthespinalcordofthe cat following intraspinal injections of lysolecithin J Neurol ... Lysolecithin-induced demyelination in wild type and NG2 null mice Use of MBP staining (green) to compare demyelinated regions inthe white matter of wild type and NG2 null mouse spinal cords one...
... the decision of continuing the ongoing therapy or stopping and redirecting the patient to other salvage therapies Our study also supports the idea of routine use of PET or preferably PET/CT in ... uptake in our study It is an important limitation that the number of patients is small especially inthe first group, the number ofstudiesinthe literature investigating the role of PET inthe ... patient andinthe proximal jejunal segments ofthe intestine in another patient were not FDG avid So they were accepted as non malignant and no therapy indication was discussed clinically As per the...
... of ligand-protein binding Power-law behaviors of ligand-protein binding The number of ligands (N) decays with an increase inthe number (L) of (a) domains and (b) folds that bind the ligand and ... binding of ligands with primordial proteins would also be a critical step inthe origin of life Thus, it is intriguing to explore the chronology of ligand-protein binding and answer the following ... release during ligand binding may meet the free energy demand during protein folding It is tempting to examine the conjecture of ligand-induced formation and/ or folding of primordial proteins through...
... ArgA145 and ArgB263, on the negatively charged COO– inthe aminic part determines the position ofthe substrate within the S1¢-binding subsite O atoms ofthe main chain CO groups of LeuB387 and TrpB240, ... atoms ofthe side chain d-guanidino group of this residue are involved in H-bonding as follows: Ne with the O atom ofthe main chain CO group ofthe TrpB240; Ng1 shares H bonding with O atom ofthe ... subsite Substrate binding induces conformational changes involving the ArgA145PheA146 fragment ofthe protein chain, acting as a flap, first opening and then closing the groove [45] The catalytic reaction...
... (GalNAcAcontaining trisaccharide repeating unit) (Fig 4A, inset), based on this ratio about 40% of GalNAcA in both CPS and O-chain polysaccharides was present inthe form of a primary amine When the carboxyl-reduced ... presence of sugars consistent with the composition of CPS and LPS O-chain polysaccharide, namely 2-amino-2-deoxy-Dquinovose, 3-amino-3-deoxy-D-quinovose and 2-amino2-deoxy-D-galacturonic acid, inthe ... during the 72-h in vivo culture period In addition, sugars detected inthe inoculum TSB culture were also present Based on sugar ratios of 3-amino-3-deoxy-D-quinovose and L-rhamnose, 10% of the...
... medication for PsA in Finland inthe years 1990 and 1995 A total of 65 incident cases of PsA were identified inthe 1990 study, resulting in an annual incidence of per 100,000 ofthe adult population ... with men, in whom the rate increased steadily from 1950 to 1974 and then began to decline during the late 1970s and early 1980s The same finding of different secular trends, according to sex, ... recently there have been very few studies on the epidemiology of gout In 1967, a study using the Framingham data reported the prevalence of gout at 1.5% (2.8% in men and 0.4% in women) [78] In England,...
... increase inthe conduction velocity along the whole motor nerve from thespinalcord to the site ofthe recording electrode located very close to the muscle These results confirm the finding in paralyzed ... reported that in SCI rats there was an increase inthe excitability ofthe afferent neurons innervating urinary bladder but there was no change in neurons innervating the colon Inferences from the present ... paper RF assisted in data analysis and revising the manuscript AW assisted in interpreting the data andin writing and revising the manuscript All authors read and approve the final manuscript...
... finding hospitals (the points in Figure 1.3a), streams (the line segments in Figure 1.3b), and parks (the continuous-line polygons in Figure 1.3c) in a given area (the broken-line polygon in Figures ... the distance between two points, ofthe length of a line consisting of straight segments, ofthe area of a polygon, ofthe angle of a slope, and so forth A second set of operations is used for ... from the University of Pennsylvania in 1975 and his doctoral degree in Engineering from the University of Tokyo in 1977 Previously he has held the position of Associate Professor at the Institute...
... viewpoint implies that the meaning of data is not inherent inthe data itself, but rather resides inthe structures into which the data is incorporated Data is, in itself, only useful when set into ... that, they leave the target area, analyze the data collected, and compile a summary of their studies Through this process of postanalysis, the researcher can gain a new understanding regarding the ... specifies the same feature or area in two photos by drawing a rectangle or polygon on each ofthe two photos Inthe example shown in Figure 2.10, the same building appears in two photos, andthe user...
... GIS-based Studiesinthe Humanities and Social Sciences vation o exca Link t d order n time a record record record record record record record record Time record Excavation schedule FIGURE 3.6 Links of ... for Acquiring Archaeological Data 41 record record record record Link to location and strata record record Links generated in data acquisition record record record GIS (Geographic Information ... Links of individual records of archaeological relics and remains to excavation timetables Link to record record docum ents record record record record record record Report or article record Analysis/...
... an initial position and velocity ofthe feet at the beginning half ofthe swing phase, then remain inactive throughout the rest half ofthe swing phase Here the initial position refers to the ... foot swings by, pivoting on the other foot The two feet interchange inthe step by landing and then shifting in a rhythmic pattern According to the ballistic walking model proposed by Mochon and ... all the client computers and integrates them into the global coordinate system to make a frame (Step 4.3.1) Since there may be many points impinging upon the same foot, where the number of points...
... the number of sample points included inthe area of buildings to the population data The relationship between the actual population of each village P, andthe number of sample points within the ... analysis ofthe changing pattern of population throughout the period from the beginning ofthe Japanese modern era to the present day The chapter consists of six sections, including this introductory ... grid of 20-meter intervals on a map and regarded the lattice points as systematic sample points The number of such points included inthe area of buildings was counted (Figure 5.1) Let N be the...
... core and also satisfy the commuting-ratio requirement for being an outlying area ofthe other municipality, the one with the lowest commuting ratio is inthe core, andthe other is its outlying ... being an outlying area ofthe other municipality, the one with the lowest commuting ratio is inthe core, andthe other is its outlying area (a) A municipality is a first-order outlying area of ... identified inthe first iteration, those that satisfy the following two requirements are included inthe cores ofthe UEAs to which they belong If a candidate is a “major” city, it is included in the...
... GIS-based Studiesinthe Humanities and Social Sciences enables the management and searching of a single database containing archaeological information collected in Japan, Britain, andthe U.S.A The ... integrating notations and semantics (Worboys, 1994) This chapter introduces the research findings inthe data modeling of archaeological information with the aim of effective information sharing and ... enabling the integration of general-information systems and GIS Moreover, with the application of geographic-information standards, the defining processes of archaeological feature shapes and time...
... characteristics of a surface in terms ofthe configuration of “peaks,” “col,” and “bottoms,” (Figure 8.12) They vary, in that the rules for joining these critical points (the continuous lines in Figure ... at a finite number of points inthe region (the points in Figure 8.11), and so we have to estimate the surface (the surface in Figure 8.11) In this case, we click on “Estimation of a surface” (Section ... (Abstract), the annual meeting ofthe Association of American Geographers, New Orleans, 2003 Okabe, A and Yoshikawa, T., SAINF: A toolbox for analyzing the effect of point-like, line-like and polygon-like...
... Examining the Effect We consider an example of how to use SAINF by examining thein uence of three infrastructural elements on the location of luxury apartment buildings in Kohtoh, Tokyo These ... for the result We put inthe names of these file, andin a few seconds, a display, such as the one in Table 9.2, is shown As stated inthe hypothesis H’o, if the hypothesis Ho was valid, the observed ... to count the observed number of points placed in R(di , di +1 ) We click on “Number of non-infra features” inthe “SAINF-Tools” menu, and a dialog box appears, showing the layer of noninfrastructural...
... 10.3 Software and Data Setting The software SANET consists of two components: the main program, andthe interface between this and a GIS viewer The main program performs the geometric and algebraic ... realized set of points for the streets in Shibuya-Shinjuku using Tool (the number of points is the same as that in Figure 10.3) To obtain the expected K function, as many as 1000 sets of points are ... and Okabe (2004) To explain the meaning of a “clump,” we define the r-neighborhood of a point, p i , as the sub-network of a network in which the shortest-path distance from p i to any point in...
... analysis, for the starting point andthe destination ofthe route, as well as most of buildings appearing in this description cannot be identified by the analysis ofthe text, and hence the route ... is judged by the coincidence of building use inthe 1920s, the reliability of this judgment is rather low, and hence is given for the weight On the other hand, a road branching off and a description ... 11.3.2 Consistency of Branching Off of Road If the road is branching off into the same or larger number of roads in Sayyed Reza Khan’s map, then the link is judged consistent with the phrase This...
... with the highest at 699 m and others more than 400 m dotting the landscape Settlements are formed along the rivers and on slopes facing the sea, and these rely mainly on rice farming The northern ... estimated from landforms will enable further understanding of ironworking and other crafts in addition to the fishing discussed here, and also will enable estimates ofthe roles of other economic ... resulting values are the first to the 50th largest, and their diameters correspond to their values Note that once the ith largest cell is determined, the values ofthe cells within the radius of...
... considered the physical remains ofthe hunt We should deepen the historical understanding of a site by interpreting the physical remains in a social context For example, even if the shell mound of a ... (polygons) andthe spatial distribution of pottery, stone artifacts, dwellings, and other remains These data were recorded with their locations, but we often met the following difficulties The boundary ... of areas contained within a certain time radius of walking We conclude inthe historical interpretation that the two distinctive characteristics ofthe Sannai-Maruyama site are a very large and...