a b feature vectors of compounds with the property e f feature vectors of compounds without the property feature vector hj pj vj represents such structural and physicochemical properties as hydrophobicity volume polarizability etc
Machine learning approach in pharmacokinetics and toxicity prediction
... limited number of compounds and these data are rarely determined by the same protocol Thus data selection has been primarily based on such considerations as the comparison of the data of the compounds ... which give ADMET data that are closer to the median of the values from the different sources are more accurate In classification problems, the most common range of the ADMET data for the compounds ... Ideally, these ADMET properties should be measured by a < /b> single protocol so that different compounds can be reliably compared with each other However, human ADMET data have been determined only for a...
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Polystyrene (PS) waste plastic conversion into aviation /kerosene category of fuel by using fractional column distillation process
... city chain store Wal-Mart PS waste plastic comes with other foreign materials and PS waste plastic and other foreign materials separated manually Then PS waste plastic washed with soap and water ... the research and development field as a < /b> laboratory Chemist in the company of Natural State Research, Inc He is co-author of several publications about waste plastic to fuel related journal He ... number small and bulky both functional groups are available and in low wave number double bond and single bond functional groups are available such as methane group, cis and trans alkene etc Hereafter...
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ANALYSIS OF NAMES OF ORGANIC CHEMICAL COMPOUNDS BY USING PARSER COMBINATORS AND THE GENERATIVE LEXICON THEORY doc
... the list [1, 2] of posLinkDyene and the difference-list composed of pentadyene are passed to alkadyeneCarbonChain (the list [1, 2] is passed by means of the parameter \j) The parser alkadyeneCarbonChain, ... name Remember that, as shown in section 3, the natural language ambiguities handled by Frost, Hafiz and Callaghan not require from the system the ability of altering the lexical items of the ambiguous ... complete compounds themselves but that are part of other compound names (for example, all the alkanes, alkenes and alkynes are represented by embedded names) As shown in section 4, OCLAS extends the...
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assessing damage of flood by using alos data in thua thien - hue province - vietnam
... 3.1 Flooded area of landuse/cover types The map of landuse/cover was overlaid on the map of flooded area to calculate area and map the flooded area of landuse/cover types The result of calculation ... points of height The data such as tide, wave in the area were collected for determining the wave height and sea level at the time of obtaining images to identify mean sea level on satellite image ... distribution of flooding areas at October nd 2007 and a < /b> DEM of Thua Thien Hue coastal area, with scale of 1:25000 are established from ALOS satellite data - Flooded level of landuse/ landcover types were...
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Optimization of Cost by Using 7 QC Tools docx
... Invalid cause for the problem Why the rejected parts were oversize in between? For this we have checked the run out of the tool when the part was rejected After analyzing the problem after deep ... identified and represented in the form of cause and effect diagram as shown in figure 156 Nitin K Mandavgade and Santosh B Jaju Figure 9: Identification of probable causes Step 4: Brainstorming The ... Knowledge of operator Observation:-After interviewing the machine operator it was confirmed that they are having adequate operating and inspection knowledge Also, there was standard operating...
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A computational study of chiral separation of tryptophan by using cyclodextrin
... through the chiral film slower than the other, and, therefore, differing levels of displacements of the two enantiomers are observed as a < /b> function of time Chapter describes the advantages of and the ... order to provide information on the selection of the separation phases, there has been a < /b> classification of the basic types of CSPs based on the diastereomeric complexes formation between the chiral ... βcyclodextrin can be used to discriminate and separate the enantiomers of tryptophan However, the energy difference between the pair of diastereomeric complexes is quite small and the separation efficiency...
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Tài liệu Báo cáo khoa học: Transcriptional upregulation of inflammatory cytokines in human intestinal epithelial cells following Vibrio cholerae infection pptx
... shown) As the mRNA of interferon (IFN)-c was barely detectable in both uninfected and infected Int407 cells, protein secretion was measured by ELISA IFN-c was detected at h following infection; the ... of V cholerae are also responsible for NF-jB and CREB activation The fractionation of V cholerae culture supernatant followed by the induction of epithelial cells with each of these fractions ... (Fig 5B) , whereas the active form of CREB was observed at h of LPS treatment Such facts suggest an optimal association of transcription factors at the site of transcription of IL- 1a < /b> and IL-6 by...
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Báo cáo Y học: Purification and characterization of novel chondroitin ABC and AC lyases from Bacteroides stercoris HJ-15, a human intestinal anaerobic bacterium pptx
... phosphate buffer (pH 5.0–8.5) The temperature dependence of the enzyme was investigated by measuring enzyme activity at different temperatures (20–60 °C) To investigate the effect of divalent metal ... in the warmed holder of spectrophotometer and the change of absorbance at 232 nm was measured at 1-s intervals over The activity was calculated from the change of absorbance per minute using an ... enzymes from B thetaiotaomicron When these chondroitin sulfate ABC and AC lyases were incubated with chondroitin sulfate A,< /b> these enzymes mainly produced disaccharide and tetrasaccharide/hexasaccharide,...
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Báo cáo y học: " Prediction of viral microRNA precursors based on human microRNA precursor sequence and structural features" pot
... of different programs are summarized in Table Average Frequencies of sequence-structure feature elements Average frequencies of the feature elements were compared between the positive set (validated ... employed RBF kernel and used a < /b> grid search strategy varying combinations of penalty parameter C and the Radial Bias Function (RBF) kernel parameter γ The performance of each model was assessed based ... are tagged, encoded as feature vectors and are mapped onto a < /b> feature space by the kernel function, with the aim of seeking a < /b> function that defines a < /b> global hyper-plane that would optimally separate...
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Báo cáo sinh học: " Effects of the number of markers per haplotype and clustering of haplotypes on the accuracy of QTL mapping and prediction of genomic breeding values" pot
... simulated dataset was: matrix based on the pedigree of the last four generations of animals and s G is the polygenic variance The esti- mated haplotype variance at each locus was calculated as ... information The bias of the predicted total breeding values of juvenile animals was also evaluated, by plotting the difference between simulated and predicted total breeding values for the juvenile ... aim of this paper was to investigate the effect of the number of surrounding marker alleles (window size) included in base haplotypes and the effect of clustering of base haplotypes based on IBD...
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Báo cáo sinh học: " Impacts of both reference population size and inclusion of a residual polygenic effect on the accuracy of genomic prediction" potx
... marker effects and the variance of DGVt, which was defined as the sum of DGV and the estimate of the residual polygenic effect, and their correlations with conventional EBV for the reference bulls ... The GEBV and parental average of pedigree-based EBV of the validation bulls were compared to their actual deregressed MACE EBV to evaluate the predictive ability of the genomic model To investigate ... procedure [24] Realised reliabilities for the pedigree-based EBV and the combined GEBV of the validation bulls were computed as the square of observed correlations with deregressed EBV, adjusted...
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The transference of meaning through class of words denoting parts of the human body in english and vietnames
... Vietnamese, we have the tables sum up the percentage of the forms of each types of semantic transference and the percentage of the types of semantic transference used in these classes Table 2: The ... the earth The hand of a < /b> child - The hand of a < /b> lock The heart of a < /b> man - The heart of a < /b> matter 37 The tongue of a < /b> man - The tongue of a < /b> shoe The tooth of a < /b> person - The tooth of a < /b> comb The head ... hands - The hands of a < /b> farm 13 The heel of a < /b> person - The heel of the hand 14 One's leg - The leg of a < /b> trip 15 One's brain - The brains of a < /b> family 16 The bosom of a < /b> person - The bosom of the...
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A contrastive analysis of metaphors relating to parts of human body in english and vietnamese
... 97AA6< , • B 96:;:< , # / 96::?< " s ) • =3 & 96:::< ? " 0B - D 2 96: :F 97AA7< " # ) z 97AAA< , ##5 ) 51mmm6 ... ^ ! 7AA6, 6 8F> < , U e ( T ' i ( R ^ & + U S ' * ( & T ' ,) U j * ) k" XNY V * U ^ * [ 7AA8, ?FA< Z W Y ( T ' * ( ' ( T ' " " - " H- % & ( & & h 9& -' , ( ( ' !* * ' D 6::8, F? F< + ( f' ( f' %...
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Tài liệu Báo cáo khoa học: Investigation and prediction of the severity of p53 mutants using parameters from structural calculations pptx
... limit between the classes was set to the activity value of 25%, because this value was observed to be a < /b> natural divider of the data The algorithm was also evaluated with other separation limits between ... were evaluated If the score was improved, the parameters were retained; if the score was impaired, the recent change was rejected However, if no improvements were found after a < /b> predefined number ... high-energy regions, were made Changes which decreased the energy were always retained, whereas changes that increased the energy were kept with a < /b> probability that decreased exponentially with increasing...
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Tài liệu Báo cáo khoa học: Allosteric modulation of myristate and Mn(III)heme binding to human serum albumin Optical and NMR spectroscopy characterization pptx
... with respect to Mn(III)heme were taken and the binding isotherm was analyzed by plotting the difference of absorbance between the maximum and the minimum of the two-signed difference spectra against ... concentration of paramagnetic agent) were determined by subtracting from the observed relaxation rate (R1obs ) the blank relaxation rate value (R1dia ) measured for the buffer at the experimental ... place the carboxylate head of the fatty acid, thus Fig Ribbon representation of the heart-shaped structure of HSA with the seven fatty acid binding sites labeled (FA1 to FA7); sites are occupied...
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Tài liệu Báo cáo khoa học: "Evaluating the Accuracy of an Unlexicalized Statistical Parser on the PARC DepBank" docx
... these results provide a < /b> reasonably accurate idea of the XLE parser’s relative performance on different features and relations Where we believe that the information captured by a < /b> DepBank feature ... However, DepBank treats the majority of prenominal modifiers as adjectives rather than nouns and, therefore, associates them with an adegree rather than a < /b> num feature The PoS tag selected depends ... 79 Table 1: Accuracy of our parser, and where roughly comparable, the XLE as reported by King et al croaverages The macroaverage is calculated by taking the average of each measure for each individual...
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Tài liệu Báo cáo khoa học: Role of cleavage and shedding in human thyrotropin receptor function and trafficking pdf
... 2A,< /b> see also Fig 4C) Increased basal internalization of the b1 mutant receptor A < /b> decreased cell surface expression of the b1 mutant receptor was observed when compared with the wild-type receptor ... dishes and transfected as described above Forty-eight hours later, membrane extracts were prepared as described [15] The extracts were loaded on a < /b> 10% SDS/PAGE and Western blot analysis were performed ... similarities with the ADAM (A < /b> Disintegrin and Metalloprotease) family of metalloproteases [12,18] The cleavage and shedding of the human TSHR may be of physiological importance because the precise quantification...
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Báo cáo " Assessment of the influence of interpolation techniques on the accuracy of digital elevation model " potx
... Field: add the Elev_Diff field to the feature class Extracted Pts - Calculate Field: calculates the elevation difference ∆ i by using Eq and takes its square value - Summary Statistics: calculates ... points will have two attributes: the original Elevation, and the extracted from DEM Int_Elevation These attributes are compared each with other to derive the elevation difference ∆ i for each point ... countries, the results of these research sometimes are contrary each to others This research investigates the influence of interpolation techniques on the accuracy of DEM in the examples of four projects...
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Báo cáo khoa học: Limited mutagenesis increases the stability of human carboxypeptidase U (TAFIa) and demonstrates the importance of CPU stability over proCPU concentration in down-regulating fibrinolysis doc
... favour the formation of H-bonds with one or several of these residues, attenuating the charge repulsions between some of the basic amino acids The stabilization induced by the replacement of H357 by ... twice more The depleted plasma showed no measurable proCPU, as detected by the reference HPLC-assisted assay ProCPU-depleted plasma was reconstituted with increasing amounts of activated WT and YQ ... instability of activity ‘Directed evolution’ approaches allow the random generation of a < /b> large number of mutants followed by selection for the desired features Several proteins have been changed...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam nội dung cụ thể cho từng kĩ năng ở từng cấp độ phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25