... AMIGO and examined the expression and localization of AMIGO in brain sections at the cellular level In order to gain a better understanding of functional domains of AMIGO, we generated AMIGO-LRR and ... (ClustalW) and schematic structural illustration ofof human NgR1, NgR2 and NgR3 A: The sequence alignment (ClustalW) of human NgR1 NgR2 and NgR3 Signal sequences (underlined), LRRNT, LRR 1-8, LRRCT and ... of DNA (or 0.8 μg of interest DNA with 0.2 μg of Enhanced Green Fluorescence Protein (EGFP) expression plasmid) with 2.5 μl of Lipofectamine 2000 Cells were then fixed and prepared for immunofluorescence...
... adipocytes and the adipose microvascualture, and the marked similarities in tumor growth and hypoxia compared with those of adipose tissue expansion remain of great interest Adipose tissueand lymphatic ... [6] At the other end of the spectrum is the condition of lipodystrophy, wherein the dramatic loss of adipose tissue triggers a high degree of insulin resistance and signs of other metabolic dysregulation ... quality of adipose tissue consistently point to the microvasculature and angiogenesis within adipose tissue as critical role players in adipose tissue health and expansion [3] Expansion of adult...
... between polh protein expression and oxaliplatin sensitivity of gastric cancer cell lines and the significance of that in predicting treatment responseand survival of metastatic gastric cancer patients ... design of the study RZL and HZZ reviewed the IHC slices ZQW and YHL participated in the statistical analysis RHX conceived of the study, and participated in its design and coordination and helped ... active in about 40-50% of advanced gastric cancer patients [14-16] Oxaliplatin and cisplatin share the similar mechanism, and cause mono-adducts and intra-strand or inter-strand cross-links in the...
... in brain cortex of rats exposed to an animal model of depression This activation occurs with increased levels of the pro-inflammatory cytokine IL-1b andof one of the main enzymatic sources of ... activation in brain cortex after stress exposure in rats mRNA expression levels for TLR-4 (A) and MD-2 (C) in brain in control and after CMS Protein expression of TLR-4 (B) and MD-2 (D) in brain in ... to stress-induced TLR-4 and MD-2 up-regulation at protein and mRNA levels, and to all of the other inflammatory and oxidative parameters previously determined in braintissue (Table 1) Interestingly,...
... Journal of Physiology, vol 285, pp 197–207, 1978 [29] B Harazin and J Grzesik, “The transmission of vertical wholebody vibration to the body segments of standing subjects,” Journal of Sound and Vibration, ... frequency, and ξ is the dumping ratio Model parameters (ωn and ξ) were estimated by utilizing the values of the dominant peak (amplitude and frequency) of the experimental frequency response; ... frequencies In particular we evaluate the symmetry of muscle motion and the similarity of frequency response between lower limbs For each posture and for all of the muscles analyzed we computed the correlation...
... for Mp and 0.362 for Sp The whole-ring values of standard deviation were in magnitude order of 0.201 for Df, 0.138 for Ns and 0.106 for Mp, giving coefficients of variation of 47%, 38% and 28% ... regression analyses of RW and lambda parameters for each of the three examined species Environmental and genetic (clone) control of the variability of distribution position and shape was examined ... parameters (e.g values of kur lower than and values of qkur lower than imply a peaked distribution) The upper tail length (utl) was especially high in Ns and earlywood of Df and Mp 3.2 Modelling within-ring...
... TetTox (a) Example of restricted pattern ofresponse to antigens Bars indicate mean proliferation and standard deviations of triplicate values (b) The proliferative responses to SLO and TT observed ... induction of migration, adhesion, andtissue infiltration of monocytes and polymorphonuclear leukocytes J Exp Med 1994, 180:203-209 Badolato R, Oppenheim J: Role of cytokines, acute-phase proteins, and ... proliferation and standard deviations of triplicate values T cell proliferative responses were judged to be different between the synovial fluid and peripheral blood compartments if the standard deviations...
... transmittance of the sun’s beam Agric For Meteorol 55 Lang ARG (1991) Application of some of Cauchy’s theorems to estimation of surface areas of leaves, needles and branches of plants, and light ... radiation: measurements andmodelling Agric For Meteorol 78, 121-131 Berbigier P, Bonnefond JM (1995) Measurement andmodellingof radiation transmission within a stand of maritime pine (Pinus ... PAR reflectance of the understorey Reflectance (p) and transmittance (τ) in the PAR waveband on needles of τ) analytical solution of these equations given by Bonhomme and Varlet- Grancher...
... WBRT and boost The 1-year survival andbrain control rates were 65% and 70% after WBRT plus SRS, and 63% and 78% after surgery plus WBRT and boost, respectively Based on the present results and ... design, analysis and interpretation of data, and helped to draft the manuscript EC and MFO performed the statistical analysis and participated in acquisition and analysis of data AB and RME critically ... survival rates were 58% and 24%, and respective brain control rates were 43% and 22% Sixteen patients recurred locally after SRS with 1-year and 2-year local control of 92% and 84%, respectively...
... (67 of 131) (22 of 47) 71% 76% 72% 65% (number of patients) (136 of 192) (22 of 29) (88 of 123) (26 of 40) Two-year drug survival (number of patients) 66% (97 of 148) 70% (19 of 27) 69% (66 of ... 45% (number of patients) (104 of 214) (19 of 30) (62 of 133) (23 of 51) ASAS40 responders at six months (number of patients) 46% (97 of 209) 52% (16 of 31) 48% (63 of 131) 38% (18 of 47) BASDAI50 ... 66% 65% (145 of 214) (24 of 30) (88 of 133) (33 of 51) 63% 71% 66% 51% (132 of 209) (22 of 31) (86 of 131) (24 of 47) (number of patients) ASAS20 responders at six months (number of patients)...
... design of the study and interpretation of in vivo data and writing the manuscript JSE participated in the design of the study and helped to perform the in vivo procedures All authors read and approved ... airway tissueand lumen eosinophilia Post-challenge intra-nasal administration of anti-Fas mAb to the lungs of these mice decreased the number of eosinophils in the airway lumen (BALF) at and 24 ... Fas-induced apoptosis of lung tissue eosinophils and insufficient clearance of apoptotic eosinophils The airway tissue eosinophilia was not reduced by antiFas mAb treatment (Figure 2B, and 2C) Yet, contrasting...
... design of the study, data collection, analysis, interpretation of data and writing of the manuscript FM actively participated in the conception and design of the study, interpretation of data and ... because of the small size of the sample (N = 20) R675 In severe TBI, the risk ofbraintissue hypoxia is common when CPP is below 60 mmHg, less frequent when it is between 60 and 70 mmHg, and lower ... stable in order to identify and correct causes of non-ischemic hypoxia [18] The principal causes of low-extractivity hypoxia, such as anemia and hypoxemia, and the causes of high-affinity hypoxia...
... records and p3 is the number of random regression coefficients used to model this permanent environmental effect Matrices W, Z , and Z are design matrices with covariates of the curve The random vectors ... during the first half of the period and nearly null during the second half, the QTL was detected in 95 percent of the cases with the random regression model and only 16 percent of the time with the ... detected here in 98 percent of the cases with the random regression model and only percent of the time with the 305d model Given the estimated parameters of the random regression model, the variances...
... discovery of penicillin by Alexander Fleming (9) The introduction of structure of penicillin began the new era of antibiotics, and greatly improved control, treatment and prevention of bacterial ... class No of Descriptors in Class Descriptors Simple molecular properties 18 no of C, N, O, P, S, no of total atoms, no of rings, no of bonds, no of non-H bonds, MW, no of rotatable bonds, no of H-bond ... phase and applied phase The research phase consists of target identification and validation, and lead identification and optimization The clinical phase consists of evaluating the safety and efficacy...
... tilting of the specimen; (3) bending error on bottom and top of the specimen; (4) strain non-uniformity of the specimen caused by end restraints, leading to bulging of the specimen; and (5) strain ... Vertical deflection Strain Mean strain Elastic strain Plastic strain ̃ Equivalent plastic strain ̃ Compression crushing strain ̃ Tensile cracking strain b Total unit weight Strain mobilization ... whole regime of stress -strain curve is nonlinear and decreases with strain increment The adopted 13 Young’s modulus is the tangent modulus of the initial, linear portion of stress -strain curve...
... requirement of soft tissue modeling 1.2 Variational methods for soft tissue modeling Many studies have been conducted to investigate the biomechanical models of soft tissue Deformable models for soft tissue ... data often comprise of a number of stress -strain curves with large deviations [101] Material parameters of soft tissue model are usually characterized using the mean stress -strain curve and ignoring ... presentation of soft tissue deformation during interactions similar to that of actual surgical manipulations The boundary conditions of soft tissues must be physically well defined and 1 their...
... calculated 80 Table 5.1 Geometrical parameters of nanofins used in this study where h refers to the height of the nanofins, and definitions of p, q, m and n can be found in Figure 5.4 Important parameters ... enhancement factor r roughness of the textured surface (ratio of the actual surface area to projected area) s fraction of area of the solid tops, i.e ratio of the area of the top of the nanostructure ... cell of nanofin could be effectively approximated with a nanochannel of equivalent height and length that contains the same volume of liquid The energy dissipated by the form drag per unit cell of...
... is a group of polyanionic polymers consisting of orthophosphate PolyP is present in numerous bacterial and archaeal cells, and also, in plant and animal tissues The wide distribution of polyP suggests ... precise roles of GAO are still not verified PHAs, glycogen and polyP are the three key biopolymers in the metabolism of PAO and GAO in the EBPR process To understand the EBPR process and its performance, ... supervisors, Associate Professor Liu Wen-Tso and Professor Ong Say Leong, for their meaningful advice, constructive suggestions and supervision in all aspects of my graduate career, and, moreover, for...
... on the 2/4 Development and Regeneration of Muscle Tissue proper use of equipment, such as crutches, and assess whether someone has sufficient strength to use the equipment and when they can function ... readily than skeletal and cardiac muscle tissue Similar to skeletal muscle tissue, cardiac muscle does not regenerate to a great extent Dead cardiac muscle tissue is replaced by scar tissue, which cannot ... effects of agerelated atrophy and improve muscle function The goal of a physiotherapist is to improve physical functioning and reduce functional impairments; this is achieved by understanding...
... the literature [24] The affected and the unaffected brain tissues as well as the whole brainof the HD andof control mice were used for our studies The affected brain regions were identified by ... half -brain (see above) of five of each transgenic and control mice were used for neuropathological evaluation The other half of the brain was deep frozen In addition to hematoxylin and eosin and ... HD In extracts of the posterior brain region of control and HD mice in the presence of excess ATP, NAD+, inorganic phosphate and glucose, we determined the total concentration of the triosephosphates...