0

1 600 kda completely blocked both lung neutrophil and monocyte infiltration induced by mechanical ventilation

Báo cáo y học:

Báo cáo y học: "High-molecular-weight hyaluronan – a possible new treatment for sepsis-induced lung injury: a preclinical study in mechanically ventilated rats" ppsx

Báo cáo khoa học

... 0.025% of 1, 600 kDa HMW HA 12 5 ± 72 ± 442 ± 21 448 ± 9* LPS + 0.5% of 1, 600 kDa HMW HA 11 2 ± 86 ± 475 ± 17 445 ± 10 * LPS + 0 .1% of 1, 600 kDa HMW HA 97 ± 16 87 ± 495 ± 18 4 01 ± 23* LPS + 0 .1% sodium ... scores (Figures and 3) The inhibition of lung injury by 1, 600 kDa HA and not 35 kDa HA correlated with 1, 600 kDa HA inhibition of IL -1 Pretreatment with both 1, 600 kDa and 35 kDa hyaluronan inhibited ... high-molecular-weight hyaluronan (1, 600 kDa) completely blocked both lung neutrophil and monocyte infiltration Animals were pretreated with either 1, 600 kDa or 35 kDa hyaluronan 18 hours prior to ventilation Lipopolysaccharide...
  • 11
  • 297
  • 0
báo cáo hóa học:

báo cáo hóa học: " Interleukin 1 receptor antagonist knockout mice show enhanced microglial activation and neuronal damage induced by intracerebroventricular infusion of human β-amyloid" pdf

Hóa học - Dầu khí

... http://www.jneuroinflammation.com/content/2 /1/ 15 10 11 12 13 14 15 Acknowledgements We thank Sara Medgysi for assistance with mouse colony maintenance and assays These studies were supported in part by the Institute for ... Neurobiol 19 95, 21: 290-3 01 Das S, Potter H: Expression of the Alzheimer amyloid-promoting factors 1- antichymotrypsin and apolipoprotein E is induced in astrocytes by IL -1 Neuron 19 95, 14 :447-456 ... the Study of Aging (DMW) and by NIH grants R37 AG13939 (LVE), R 01 AG20243 (LVE), and P 01 AG 211 84 (LVE, DMW) JMC is a predoctoral fellow of the Center for Drug Discovery and Chemical Biology training...
  • 9
  • 307
  • 0
Báo cáo y học:

Báo cáo y học: " Reducing ventilator-induced lung injury and other organ injury by the prone position" ppt

Báo cáo khoa học

... volume, and positive end-expiratory pressure Am Rev Respir Dis 19 88, 13 7 :11 59 -11 64 11 Muscedere JG, Muller JB, Gan K, Slutsky AS: Tidal ventilation at low airway pressures can augment lung injury ... 19 94, 14 7 :13 27 -13 34 Page of (page number not for citation purposes) 12 Albert RK, Hubmayr RD: The prone position eliminates compression of the lungs by the heart Am J Respir Crit Care 2000, 16 1 :16 60 -16 65 ... Crit Care 2000, 16 1 :16 60 -16 65 13 Imai Y, Parodo J, Kajikawa O, De Perrot M, Fischer S, Edwards V, Cutz E, Liu M, Keshavjee S, Martin TR, et al.: Injurious mechanical ventilation and end-organ epithelial...
  • 2
  • 204
  • 0
Báo cáo y học:

Báo cáo y học: "Alveolar instability caused by mechanical ventilation initially damages the nondependent normal lung" ppt

Báo cáo khoa học

... 302.2 ± 17 .62 289 ± 18 .33 296.4 ± 20.85 290.78 ± 26.85 308.4 ± 32 .11 Tidal volume (ml) 6.9 ± 1. 53 11 .5 ± 1. 01 11. 9 ± 1. 37 12 .3 ± 1. 16 12 .1 ± 1. 18 12 .9 ± 1. 25 11 .7 ± 1. 33 Lung static compliance ... 17 .18 300.6 ± 10 .66 294.5 ± 17 .62 292.5 ± 21. 46 3 31. 7 ± 1. 79 333.8 ± 14 .23 Tidal volume (ml) 6.2 ± 0.55 3.8 ± 1. 06* 3 .1 ± 1. 08* 3 .1 ± 1. 08* 2.4 ± 1. 02* 2.5 ± 1. 05* 2.5 ± 1. 07* Lung static compliance ... 2.88 Ventilation positive end-expiratory pressure cmH2O (n = 9) PCO2 31 ± 3.67 26.4 ± 4.27 22.5 ± 2 .17 17 .8 ± 1. 82 17 .4 ± 2.34 18 ± 2.40 17 .25 ± 3.26 PO2 228.5 ± 24. 91 293.4 ± 18 .33 302.2 ± 17 .62...
  • 10
  • 184
  • 0
(1) how learners approach learning, both in and out of classrooms, and (2) the kinds of strategies and cognitive processing they use in second language acquisition

(1) how learners approach learning, both in and out of classrooms, and (2) the kinds of strategies and cognitive processing they use in second language acquisition

Kinh tế - Quản lý

... Oxford, 19 89; Green & Oxford, 19 95; 32 Kaylani, 19 96; Noguchi, 19 91; Nyikos, 19 90; Oxford, 19 93; Oxford & Ehrman, 19 93; Oxford & Nyikos, 19 89; Politzer, 19 83; Sy, 19 94 & 19 95; Willing, 19 88; Yang, 19 92& ... & Oxford, 19 95; Kaylani, 19 96; Lan & Oxford, 2003; Oxford, 19 96; Oxford & Ehrman, 19 95; Philips, 19 91) Ehrman (19 90) and Chamot et al (19 87) find the differences in both the range and the frequency ... gender and strategy use have come to mixed conclusions Ehrman and Oxford (19 89) and Oxford and Nyikos (19 89) discovered distinct gender differences in strategy use The study by Green and Oxford (19 95)...
  • 83
  • 622
  • 0
Tài liệu Báo cáo khoa học: 1,5-Diamino-2-pentyne is both a substrate and inactivator of plant copper amine oxidases ppt

Tài liệu Báo cáo khoa học: 1,5-Diamino-2-pentyne is both a substrate and inactivator of plant copper amine oxidases ppt

Báo cáo khoa học

... collisioninduced fragmentation of the parent ion belonging to the DAPY oxidation product (m/z 17 8 .1) fragmentation peaks were observed with m/z 16 1 .1, 14 9 .1, 14 4 .1, 13 5 .1, 13 2 .1, 12 0 .1, 10 9 .1, 95.0 and ... Floris, G (20 01) The reductive 10 11 12 13 14 15 16 17 18 19 20 21 and oxidative half-reactions and the role of copper ions in plant and mammalian copper-amine oxidases Eur J Inorg Chem 1, 35–42 Medda, ... provided the following m/z values and elemental composition of ions: 16 1 .11 (C10H13N2), 14 9 .11 (C9H13N2), 13 5.09 (C8H11N2), 10 9.08 (C6H9N2), 95.06 (C5H7N2) and 82.06 (C5H8N) Ó FEBS 2004 4704...
  • 13
  • 604
  • 0
Báo cáo khoa học: Downregulation of protease-activated receptor-1 in human lung fibroblasts is specifically mediated by the prostaglandin E2 receptor EP2 through cAMP elevation and protein kinase A pot

Báo cáo khoa học: Downregulation of protease-activated receptor-1 in human lung fibroblasts is specifically mediated by the prostaglandin E2 receptor EP2 through cAMP elevation and protein kinase A pot

Báo cáo khoa học

... ATCC and 13 21N1 cells were cultured in DMEM supplemented with 10 % fetal bovine serum and 10 0 lgÆmL )1 penicillin and streptomycin and kept at 37 °C in a humidified atmosphere of 5% (A549 cells) and ... cells and were taken as a control *P < 0.05 as compared to stimulation with PGE2 in the presence of H-89 10 0 10 1 10 2 10 3 10 4 FL1-H Fig Influence of inhibition of protein synthesis on PAR -1 expression ... used the human astrocytoma cell line 13 21N1 and the human alveolar epithelial cell line A549 In 13 21N1 cells, mithramycin A reduced the PAR -1 mRNA level by 60–75%, whereas in A549 cells, this...
  • 11
  • 338
  • 0
Báo cáo y học:

Báo cáo y học: "HIV-1 Capsid Assembly Inhibitor (CAI) Peptide: Structural Preferences and Delivery into Human Embryonic Lung Cells and Lymphocyte" pptx

Báo cáo khoa học

... References 10 11 12 13 14 15 16 17 18 19 20 21 22 UNAIDS Report on the global AIDS epidemic 2007 AIDS epidemic update UNAIDS publications 2008; 1: 3-43 Richman DD HIV chemotherapy Nature 20 01; 410 : ... processes and their mechanism of action in the intervention of the viral life cycle are not yet completely characterized Molecules like the CAP -1 [11 , 12 ] also termed PA-457 [11 , 13 , 14 ] and most ... perturbed by treatment with Triton X -10 0 solution (0 .1 % in Hank’s) on ice for minutes, followed by twice washing the cells Then 15 0 µl of Streptavidin, Alexa Fluor® 488-solution (1: 100 in PBS)...
  • 10
  • 421
  • 0
Báo cáo y học:

Báo cáo y học: "RNA interference against polo-like kinase-1 in advanced non-small cell lung cancers" doc

Báo cáo khoa học

... Biol 19 93, 13 :7793-78 01 46 Lee KS, Yuan YL, Kuriyama R, Erikson RL: Plk is an M-phase-specific protein kinase and interacts with a kinesin-like protein, CHO1/MKLP -1 Mol Cell Biol 19 95, 15 : 714 3- 715 1 ... MK, Kostas SA, Driver SE, Mello CC: Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans Nature 19 98, 3 91: 806- 811 11 Bumcrot D, Manoharan M, Koteliansky V, ... to tumor mediated by atelocollagen: Combined therapy using siRNA targeting Bcl-xL and cisplatin against prostate cancer Int J Cancer 2009, 12 5:2978-2990 doi :10 .11 86/2043- 911 3 -1- 6 Cite this article...
  • 6
  • 322
  • 0
Báo cáo y học:

Báo cáo y học: " Alpha-1-antitrypsin deficient man presenting with lung function decline associated with dust exposure: a case repor" docx

Báo cáo khoa học

... 2 011 , 5 :15 4 http://www.jmedicalcasereports.com/content/5 /1/ 154 Page of 5 Volume in Liters (FEV1, FVC) 4.5 4.5 FEV1 FEF 25-75 3.5 3.5 3 2.5 2.5 2 1. 5 1. 5 1 0.5 0.5 10 09 08 07 06 05 04 03 02 01 ... into account 18 serial measurements taken over 2 41 months, analyzed by least squares regression, the patient’s FEV1 fell by 77 ml/year, FVC fell by 54 ml/year and FEF 25-75 fell by 11 0 ml/s/year ... Weiden MD, Prezant DJ: Accelerated spirometric decline in 1 antitrypsin deficient New York City firefighters Chest 2 010 , 13 8 :11 16 -11 24 10 Akbar-Khanzadeh F, Milz SA, Wagner CD, Bisesi MS, Ames...
  • 4
  • 284
  • 0
báo cáo khoa học:

báo cáo khoa học: " DNA ligase 1 deficient plants display severe growth defects and delayed repair of both DNA single and double strand breaks" potx

Báo cáo khoa học

... http://www.biomedcentral.com /14 71- 2229/9/79 References 10 11 12 13 14 15 16 17 18 19 20 21 22 23 Molinier J, Ries G, Zipfel C, Hohn B: Transgeneration memory of stress in plants Nature 2006, 442( 710 6) :10 46 -10 49 Ries ... http://www.biomedcentral.com /14 71- 2229/9/79 A B 35 18 col 30 leaf length /mm root length /mm 25 LIG1-RNAiA 20 15 10 LIG1-RNAiB 14 LIG1-RNAiA 12 10 0 time /days 10 D 12 col0 20 25 30 45 40 cell diameter /microns LIG1-RNAiB ... LIG1-RNAiB 10 15 time/ days C LIG1-RNAiA leaf width /mm col0 16 LIG1-RNAiB 35 30 25 20 15 10 0 15 20 E 25 Col0 30 LIG1-RNAiB F time /days 4C Number of nuclei 4C Number of nuclei LIG1-RNAiA 8C 2C 16 C...
  • 12
  • 221
  • 0
thiết kế nhà máy sản xuất mì chính hiện đại năng suất 1.600 tấn sản phẩmnăm từ nguyên liệu tinh bột sắn

thiết kế nhà máy sản xuất mì chính hiện đại năng suất 1.600 tấn sản phẩmnăm từ nguyên liệu tinh bột sắn

Báo cáo khoa học

... mực, v.v… Thời gian :  90 phút cho nhóm Khoa Sơ Cấp Nghề www.ispace.edu.vn HỎI VÀ ĐÁP LEANING BY DOING ...
  • 76
  • 847
  • 5
Báo cáo y học:

Báo cáo y học: "Emulsified Isoflurane Preconditioning Reduces Lung Injury Induced By Hepatic Ischemia/Reperfusion in Rats"

Y học thưởng thức

... hepatic I/R Neutrophil recruitment in the lung was assessed by measuring tissue MPO content Lung tissue MPO was low in sham rats (1. 41 0. 51 U/g), but increased to 5.5 1. 37, 5.22 1. 33 and 3. 81 1. 62 U/g ... reduced lung injury induced by hepatic I/R, as evidenced by amelioration of lung edema and neutrophil recruitment, decreased TNF-α level in the lung tissue and down-regulation of ICAM -1 Zhang ... Anesthetic -induced preconditioning: previous administration of isoflurane decreases myocardial infarct size in rabbits Anesthesiology 19 97; 87: 11 82 -11 90 http://www.medsci.org Int J Med Sci 2 011 , 8 10 11 ...
  • 9
  • 389
  • 0
DSLR 1.x crop factor vs. Full frame : Effect and reality

DSLR 1.x crop factor vs. Full frame : Effect and reality

Chụp ảnh - Quay phim

... phải tiêu chí wide angle lens Khi đắn đo 12 mm 18 mm ta quan tâm đến angle view 12 mm thật đáng kể, k0 kích thước ảnh 18 mm to ! Vậy thì, lắp 12 mm vào APS-C 1. 5x rõ ràng sensor nhỏ làm góc nhìn ảnh ... góc nhìn ảnh bị hẹp lại đáng kể Tỷ lệ tương đương với crop factor 1. 5 Như lens 12 mm APS-C 1. 5x cho ta hình có view angle hẹp 1. 5 lần so với FF Sự kết hợp làm cho người tiêu dùng bị thiệt hại ... thước ảnh cho 300mm với FF to 1. 5 lần so với kích thước ảnh cho 200mm với APS-C 1. 5x Như vậy, cho dù góc nhìn, phối cảnh nhau, ảnh 300mm với FF phóng to với tỷ lệ 1. 5 lần Có thể phóng paper, hay...
  • 11
  • 422
  • 0
Tài liệu Module 1: Introduction to Microsoft Windows 2000 File, Print, and Web Servers pdf

Tài liệu Module 1: Introduction to Microsoft Windows 2000 File, Print, and Web Servers pdf

Hệ điều hành

... provides a way for users, and other clients in a distributed environment, to name, store, and retrieve information 10 Module 1: Introduction to Microsoft Windows 2000 File, Print, and Web Servers The ... distributed environment, to name, store, and retrieve information Active Directory enhances file and print server functionality by publishing shared folders and printers so that users can locate ... printers by using a Web browser, to print by using a Web page, and to view print job information in Hypertext Markup Language (HTML) format It also allows users to connect to printers by using...
  • 16
  • 490
  • 0
Tài liệu Mechanical Ventilation for children with Lung Disease: ALI, ARDS, and Hypoxemic Respiratory Failure. docx

Tài liệu Mechanical Ventilation for children with Lung Disease: ALI, ARDS, and Hypoxemic Respiratory Failure. docx

Sức khỏe trẻ em

... 0.2 0 .15 0 .1 0.05 10 0 Count Count 10 0 12 0 Mortality 0.35 0.3 0.25 0.2 0 .15 0 .1 0.05 80 60 40 20 >10 10 n=290 12 0 10 0 ... Pulmonol 19 97; 23 :11 76 -18 3 Day OI and Mortality n =15 6; ALI 80 0.6 70 0.5 60 Number 40 0.3 30 Mortality 0.4 50 0.2 20 0 .1 10 0 25 OI Survivors Deceased Mortality Khemani and Newth, ... 0.25 0.2 0 .15 0 .1 0.05 Mortality 12 0 to 10 80 60 40 20 10 Vt (ml/kg) Day Vt and Mortality
  • 51
  • 597
  • 1
Tài liệu Báo cáo khoa học: The endogenous retinoid metabolite S-4-oxo-9-cis-13,14-dihydro-retinoic acid activates retinoic acid receptor signalling both in vitro and in vivo pdf

Tài liệu Báo cáo khoa học: The endogenous retinoid metabolite S-4-oxo-9-cis-13,14-dihydro-retinoic acid activates retinoic acid receptor signalling both in vitro and in vivo pdf

Báo cáo khoa học

... 4d234 43d234 dd234 43234, 43234 4334 234 (normal) 1 4 3 1 1 1 10 0 .1 0.2 0.5 0.2 0.5 S-4o9cDH-RA 2.5 10 10 Ethanol 11 13 PRV 64 67 93 10 0 12 19 73 85 88 90 a Digit identities are read from anterior ... regulation by retinoic acid J Lipid Res 43, 17 73 18 08 14 Tickle C (19 91) Retinoic acid and chick limb bud development Dev Suppl 1, 11 3 12 1 15 Tickle C, Alberts B, Wolpert L & Lee J (19 82) Local ... Cyp26 B 3.0 bmp-2 13 12 11 10 Hoxb-8 C 2.5 *** *** ** 2.0 1. 5 ** RER RARb2 A J P Schuchardt et al 1. 0 0.5 0.0 shh E 10 *** 2.0 * RER * 1. 0 RERshh 1. 5 0.0 Ethanol S-4o-9c-dh-RA: mg·mL 1 0.5 Ctrl: at-RA:...
  • 17
  • 406
  • 0
Tài liệu Báo cáo khoa học: Mitogen-activated protein kinase phosphatase-1 modulated JNK activation is critical for apoptosis induced by inhibitor of epidermal growth factor receptor-tyrosine kinase pdf

Tài liệu Báo cáo khoa học: Mitogen-activated protein kinase phosphatase-1 modulated JNK activation is critical for apoptosis induced by inhibitor of epidermal growth factor receptor-tyrosine kinase pdf

Báo cáo khoa học

... inhibited the AG147 8induced JNK activation and also AG1478 -induced apoptosis These results indicate that there is a link between the decreased MKP -1 activity and AG147 8induced apoptosis: MKP -1 expression ... 276 (2009) 12 55 12 65 ª 2009 The Authors Journal compilation ª 2009 FEBS 12 61 JNK activation is critical for AG1478 -induced apoptosis K Takeuchi et al (clone 41) , p38 MAPK (pT180 ⁄ pY182) phospho-specific ... containing 13 7 mm NaCl, mm EGTA, mm EDTA, 1% Nonidet P-40, 1% Triton X -10 0, 10 0 lgÆmL )1 phenylmethanesulfonyl fluoride, lgÆmL )1 pepstatin A, lgÆmL )1 p-toluenesulfonyl-l-arginine methyl ester, lgÆmL )1 leupeptin,...
  • 11
  • 659
  • 0
Tài liệu Báo cáo khoa học: Analysis of oxidative events induced by expanded polyglutamine huntingtin exon 1 that are differentially restored by expression of heat shock proteins or treatment with an antioxidant ppt

Tài liệu Báo cáo khoa học: Analysis of oxidative events induced by expanded polyglutamine huntingtin exon 1 that are differentially restored by expression of heat shock proteins or treatment with an antioxidant ppt

Báo cáo khoa học

... and oxidation W J J Firdaus et al C 25Q 25Q +NAC Counts 40 80 12 0 16 0 200 A 10 1 10 2 FL2-H 10 3 10 4 72Q 72Q+NAC Counts 40 80 12 0 16 0 200 10 0 10 1 10 2 FL2-H 10 3 10 4 B 10 3Q 10 3Q+NAC Counts 40 80 12 0 ... was induced by httEx1-25Q-EGFP expression, and only a slight decrease (about 10 %) was induced by httEx172Q-EGFP and httEx1 -10 3Q-EGFP expression (Fig 7A) No significant effects were induced by either ... NO• increase induced by both httEx1- Huntingtin inclusions and oxidation 72Q-EGFP and httEx1 -10 3Q-EGFP polypeptides Hence, correlations again exist between NO• and ROS upregulation and the presence...
  • 18
  • 721
  • 0
Tài liệu Báo cáo khoa học: Role of transcription factor activator protein 1 (AP1) in epidermal growth factor-mediated protection against apoptosis induced by a DNA-damaging agent doc

Tài liệu Báo cáo khoa học: Role of transcription factor activator protein 1 (AP1) in epidermal growth factor-mediated protection against apoptosis induced by a DNA-damaging agent doc

Báo cáo khoa học

... 20, 10 3 11 1 17 Meisenhelder J, Suh PG, Rhee SG & Hunter T (19 89) Phospholipase C-c is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro Cell 57, 11 09 11 22 18 ... et al Role of AP1 in EGF-mediated cell protection A Fig EGF protects TMK -1 cells against apoptosis induced by ADR (A) TMK -1 cells were pretreated or not with 1, 10 or 10 0 ngÆmL )1 EGF for 48 h ... the ability of EGF to rescue TMK -1 cells, Puro2 cells, and TAM1 cells from apoptosis induced by ADR EGF sup3748 pressed ADR -induced cytotoxicity in both TMK -1 and Puro2 cells, but not in the two...
  • 13
  • 493
  • 0

Xem thêm