1 potential role of hemoglobin based oxygen carriers in trauma care
Báo cáo y học: "Fluvoxamine monotherapy for psychotic depression: the potential role of sigma-1 receptors" pps
... fluvoxamine (50 to 200 mg), but not paroxetine (20 mg), binds to sigma-1 receptors in the intact human brain at therapeutic doses [5], suggesting that sigma-1 receptors are involved in the active ... the role of sigma-1 receptors in the efficacy of fluvoxamine for psychotic depression Consent Written informed consents were obtained from the all patients in this case report Competing interests ... the beginning of treatment with fluvoxamine Discussion Here we report that fluvoxamine was effective in five patients with psychotic depression However, further studies using large numbers of patients...
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Báo cáo y học: "Fluvoxamine for aripiprazole-associated akathisia in patients with schizophrenia: a potential role of sigma-1 receptors" ppt
... pathophysiology of akathisia [1,2] At present, it is unclear whether sigma-1 receptor agonism is involved in the mechanisms of antiakathitic action of fluvoxamine Considering the important role of sigma-1 ... occupancy of sigma-1 receptors in the human brain after single oral administration of fluvoxamine: a positron emission tomography study using [11C]SA4503 Biol Psychiatry 2007, 62:878-883 14 Kerwin R, ... akathisia’) Fluvoxamine (50 mg, twice a day) was administered Substantial relief of akathisia was noted on day of fluvoxamine treatment The dose of aripiprazole was increased to 24 mg, since she still...
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Validation of chemical looping with oxygen uncoupling (CLOU) using cu based oxygen carrier and comparative study of cu, mn and co based oxygen carriers using ASPEN plus
... it is of interest to investigate the effect of air flow rate in the air reactor on the energy output in the CLOU process In addition it is also of interest to investigate the influence of different ... with increasing air flow rate using CuO as OC for 256 g/h of coal feeding rate Table Power output from three types of coal with increasing air flow rate using CuO as OC with coal feeding rate of ... Diego L., Adanez J Demonstration of chemical-looping with oxygen uncoupling (CLOU) process in a 1.5 kWth continuously operating unit using a Cu -based oxygen- carrier, Int J Greenhouse Gas Control...
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Tài liệu Male Reproductive Health Disorders and the Potential Role of Exposure to Environmental Chemicals pdf
... causing a small but significant increased risk of TDS disorders, but not being the major sole influence explaining the majority of cases In view of the effects in rats of certain phthalates, in ... but again the percentage of cases arising because of TDS remains uncertain Even if it is accepted that many cases of TDS disorders have their origins in fetal life, identifying the causes of TDS ... causing or contributing to TDS disorders in humans, assuming a sufficient level of exposure of the fetus Overview of experimental animal studies involving environmental chemical (EC) induction of...
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Tài liệu Báo cáo khoa học: Emerging pathways in genetic Parkinson’s disease: Potential role of ceramide metabolism in Lewy body disease pptx
... a key role in our understanding of the mechanisms of the disease We propose that pathology data will, in most cases, be more insightful than clinical data in defining the disease This is based ... phospholipase A2 participates in ER stress-induced INS-1 insulinoma cell apoptosis by promoting ceramide generation via hydrolysis of sphingomyelins by neutral sphingomyelinase Biochemistry 46, 10170– ... transport of cholesterol to post-lysosomal destinations Cells from NPC subjects show a decrease in acid sphingomyelinase activity, leading to the accumulation of sphingomyelin [27] Because one of the...
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Tài liệu Báo cáo khoa học: Models and mechanisms of O-O bond activation by cytochrome P450 A critical assessment of the potential role of multiple active intermediates in oxidative catalysis doc
... benzene ring of aniline to yield p-aminophenol [151] Formation of the oxygenating species has been recognized to be facilitated by the binding to HbO2 of aniline and some of its derivatives, causing ... exhibiting insignicant sequence identity with P450s in the heme-binding region [282], but bearing a C-terminal avoprotein fragment in the single polypeptide chain structurally resembling NADPH-P450 ... (1983) Mechanisms of extrahepatic bioactivation of aromatic amines: the role of hemoglobin in the N-oxidation of 4-chloraniline In Extrahepatic Drug Metabolism and Chemical Carcinogenesis (Rydstrom,...
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Tài liệu UNIT 5. ONLINE FACILITATION LESSON 1. THE ROLE OF THE FACILITATOR pptx
... reinforcing the purpose of the group • Clarifying and reinforcing the purpose of the group • Creating a welcoming and inclusive environment that encourages • Creating a welcoming and inclusive environment ... Summarizing: summarizing involves extracting the key points from discussion, organizing them, and restating them concisely restating them concisely Observing: being able to watch and interpret ... interpret what is happening in the group, looking at both individuals and Observing: being able to watch and interpret what is happening in the group, looking at both individuals and at the group...
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MICROECONOMICSPrinciples and AnalysisFrank A. CowellSTICERD and Department of Economics London School of Economics December 2004.ii.ContentsContents List of Tables List of Figures Preface 1 Introduction 1.1 The rôle of microeconomic principles . potx
... and a list of prices w := (w1 ; w2 ; ::; wm ) for each of the m inputs respectively (mnemonic –think of wi as the “wage” of input i) Of course it may be interesting to consider forms of economic ... …gure illustrating the corner solution in (b) Interpret this …rst-order condition using the concept of the …rm’ “relative value of one input in terms of another from the …rm’ s s point of view (see ... Fourth, imagine that you are employing a thousand hours of labour at the cost-minimising point: by how much would your …rm’ costs increase if there s was in in…nitesimal increase in the wage...
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Báo cáo khoa học: The role of residues R97 and Y331 in modulating the pH optimum of an insect b-glycosidase of family 1 pdf
... side chain of E399 may have moved to a new position closer to E187, in order to minimize unfavourable interactions with the apolar side chain of F331 Thus, the increment in the pKa of E399, in addition ... determinations using mM MUbglc as substrate The pH stability of the recombinant Sfbgly50 (n) was checked by incubating the enzyme in the same buers for an equal length of time and determining the ... 2) Taking into account the experimental errors, the pKa of E187 remained the same, but the pKa of E399 clearly increased Actually, the substitution of R97 by methionine or lysine resulted in the...
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báo cáo sinh học:" Wrong schools or wrong students? The potential role of medical education in regional imbalances of the health workforce in the United Republic of Tanzania" potx
... backgrounds, schooling in a rural area, having parents living in a rural area, motivation by an interest in medicine, intended specialization in medicine, intended specialization in public health, ... with specialist training in family or rural medicine Rural practice during the training Most students had some exposure to rural areas during medical training as shown in Row of Table The few (20% ... having a rural background [24] The influence of training institutions In a survey of 189 medical students at Monash University in Australia, Somers (2000) finds that the intention to practice in...
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báo cáo hóa học: " On the potential role of glutamate transport in mental fatigue" ppt
... is indispensable for information intake and processing within the central nervous system Glutamate neurotransmission is crucial in information intake and information processing within the brain ... blood brain barrier (BBB) is seen early in neuroinflammation, and parallels the release of proinflammatory cytokines [26-28] Mechanisms for disruption of the BBB in neuroinflammation are incompletely ... ([Glu]ec in normal (IL)-1β, and ILSchematic in thefactor-α (TNF-α),) interleukinbraincytokines Figure (right)1 tumor necrosis presence of regulation of extracellular (left), and drawing of cellularthe...
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Báo cáo y học: " The potential role of appetite in predicting weight changes during treatment with olanzapine" ppt
... gain during antipsychotic drug therapy [15] An understanding of the role of appetite changes in weight gain during antipsychotic treatment would be helpful to clinicians and patients, some of ... eating; EB = Eating Behavior Assessment; EI = Eating Inventory; FCI = Food Craving Inventory; kg = kilograms; N = number of patients in study included in the current analyses; n = number of patients ... interpreting the results in a clinical context, and revised the manuscript VPH was involved in study design and conduct of the clinical studies, in design of the current analyses, contributed to interpreting...
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Báo cáo y học: " Role of common human TRIM5α variants in HIV-1 disease progression" ppsx
... family of proteins characterized by a structure comprising a RING domain, one or two B-boxes and a predicted coiledcoil region [1] In addition, most TRIM proteins have additional C-terminal domains ... pressure TRIM5α amino acid variants in the context of primate sequence conservation and of the v1 and v2 Position of Position of common human TRIM5α amino acid variants in the context of primate sequence ... TRIM5α proteins were determined by Western blotting using an anti-HA antibody (Roche) Tubulin was detected with the anti-α tubulin antibody (Sigma) Single-cycle infectivity assays in HeLa cells...
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Báo cáo y học: " Integrating findings of traditional medicine with modern pharmaceutical research: the potential role of linked open data" ppsx
... traditional Chinese medicine, gene and disease information using text mining BMC Complement Altern Med 2008, 8:58 Zhao J: Publishing Chinese medicine knowledge as Linked Data on the Web Chin Med 2010, ... Chinese medicine For researchers without a strong background in Chinese medicine, the categorization of diseases, symptoms and indications according to Chinese medicine theory can be misleading and ... [http://obofoundry.org/] doi:10.1186/1749-8546-5-43 Cite this article as: Samwald et al.: Integrating findings of traditional medicine with modern pharmaceutical research: the potential role of linked...
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Investigation of the role of the ubiquitin proteasome pathway in dengue virus life cycle 1
... to display high levels of viremia and exhibit clinical signs of dengue infection, including fever and thrombocytopenia during primary infection with clinical isolates of DENV (Omatsu et al, 2011) ... third example of a successful program was in Singapore A vector control program was initiated in 1970 following the emergence of DHF in the early 1960s This resulted in the reduction of Ae aegypti ... secondary infection alone Indeed, while DHF/DSS immediately accompanied an Asian genotype DENV-2 in Cuba in 1981 in DENV-1 immune individuals, similar sequential infection of DENV-1 in 1990 and...
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Potential applications of chitosan based hydrogels in regenerative medicine
... listed in Table 3.1 Adsorption of growth factor was carried out by immersing a pristine disc in 100 µl of loading solution containing µg/ml of BMP-2 or FGF-2 in PBS for h, followed by a rinsing ... prospect of using CMCS scaffolds as dentin remineralization patches in dentistry by assessing the mineralization inducing ability of the scaffolds in a tooth model, which represents a more clinically ... or in combination with growth factors and bone marrow in bone grafting in the forms of solid or injectable cements depending on the indications of the bone defects to assist the regeneration of...
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Synthesis, characterization and potential applications of pyrene based organic materials
... APPLICATIONS OF PYRENE BASED ORGANIC MATERIALS JHINUK GUPTA (M Sc., Indian Institute of Technology Madras, India) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF CHEMISTRY ... packing and surface topology Some of the key findings showed significant enhancement of conjugation upon successive introduction of acetylene units in the side arms of small molecules and by incorporation ... patience during the course of this work My sincere thanks to Prof S Sankararaman of Indian Institute of Technology, Madras for his support and blessings I thank all the past and present members of our...
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The role of BLNK, DOK 3 DIP in BCR signaling 1
... domain of serine/threonine protein kinase Akt/PKB and recruit it to the membrane In doing so, this leads to the activation of Akt by the serine/threonine protein kinase PDK1, suggesting a link ... activating most of the isoforms of the protein kinase C (PKC) in B cells, including PKCα, β, δ, ε, and 31 CHAPTER 1♦INTRODUCTION θ (DeFranco, 1997) PKC is a family of serine-threonine kinases ... no intrinsic protein tyrosine kinases (PTKs) activity, it utilizes several distinct families of PTKs and protein tyrosine phosphatases (PTPases) Signaling events upon engagement of the BCR involves...
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The Potential Role Of Cyber-Liability Insurance In Data Breach Litigation
... incentives for clients to practice increased information security The cyber-liability industry falls short of offering holistic information security, but further development of the industry in ... determined that “an increased risk of financial harm by an unknown third party at an unidentified point in the indefinite future” too speculative to constitute an injury -in- fact for purposes of ... plaintiffs standing for incurring an increased risk of injury from the implant of defective medical devices.32 The Pisciotta plaintiffs issued a negligence claim against Old National Bancorp Inc...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các nguyên tắc biên soạn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ lồng sóc đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25