and the living is easy
And the Winner Is: Inviting Hollywood into the Neuroscience Classroom docx
... provide a therapeutic intervention for their son Lorenzo, stricken with the rare disease adrenoleukodystrophy (ALD) Indeed, the efforts of the Odones and the foundation they established, the Myelin ... is the story of a young couple's trip to Haiti, where their wedding is to take place But, this is no vision of Haiti as an idyllic Caribbean island; almost immediately after arriving on the island, ... post-viewing discussion, I ask the class to consider a number of issues, such as: This film begins with a plea from the film’s stars, Nick Nolte and Susan Sarandon, to support the Odones' work and the...
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Distinct histone deacetylases repress expression of LH and FSH beta genes in the immature gonadotrope alphat3 1 cells and the repression is reversed by GNRH
... Hypothesis and aims The hypothesis of this study was that HDACs along with co-repressors N-CoR, SMRT and/ or Sin3A comprise distinct repressive complexes at the LH and FSH β gene promoters, and ... synthesized in and released from the hypothalamus, binds to GnRH receptors on the surface of the gonadotrope This leads to the synthesis and secretion of LH and FSH, which stimulate the production ... hormone (FSH) The pituitary gland is a small gland located at the base of the brain, functionally linked to the hypothalamus It is divided into two lobes: the anterior or front lobe and the posterior...
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Tài liệu Health of Children Living in Urban Slums in Asia and the Near East: Review of Existing Literature and Data pdf
... competent and cheerful assistance on many other aspects of the research and development of the document, and for this we thank her vi About the Authors William J Cousins William J Cousins earned his ... conclude that the rural population is more underserved, ill, and poverty-ridden than the urban and that program resources and efforts should target the rural population rather than the urban The assumption ... bear out these assumptions For understanding the health status of urban slum children, the data are misleading “Urban” data not disaggregate the poor from the not poor, the comfortable from the slum...
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Tài liệu Internet in China: Big Mama is Watching You - Internet Control and the Chinese Government doc
... behaviour is the concept of the Panopticon, invented by Bentham and mediated by Foucault The concept of the Panopticon prison depends on the visibility and individualisation of the user and the uncertainty ... record the content of the information, the time of release and the name of the website An AN also needs to record the time the user logged on, the user’s account number, the visited websites and the ... introduce the theoretical framework that is used to canvass the thesis First, the question why the original characteristics of the internet made it hard to control will be discussed Then, the view...
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Tài liệu NATURAL ENDOWMENTS, PRODUCTION TECHNOLOGIES AND THE QUALITY OF WINES IN BORDEAUX. IS IT POSSIBLE TO PRODUCE WINE ON PAVED ROADS? pot
... ratio statistic The asymptotic distribution of likelihood ratio statistic under the null hypothesis is not known a priori Therefore, one has to simulate this distribution for each hypothesis that ... Intuitively, this test calculates the "distance" between parameters obtained by OLS and by TSLS If the distance (a χ2 statistic) is small, there is no difference between OLS and TSLS, and technologies ... ecosystem, there is an additional dimension the spiritual aspect that recognizes the joys, the heartbreaks, the pride, the sweat, and the frustrations of its history." In this paper, we restrict the...
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Báo cáo khoa học: Muramyl-dipeptide-induced mitochondrial proton leak in macrophages is associated with upregulation of uncoupling protein 2 and the production of reactive oxygen and reactive nitrogen species docx
... State is defined as the phosphorylation state and is dependent on the oxygen consumption in the presence of ADP, thus reflecting the mitochondrial respiration coupled to ATP production State 4, the ... for the involvement of UCP2 in the mitochondrial impairment caused by MDP The results obtained suggested a role of UCP2 in macrophage activation by MDP The question raised at this stage is whether ... and higher ROS levels than lean mice [28] These findings agree with the hypothesis [29] that an increase in the mitochondrial membrane potential would slow the transport of electrons through the...
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Báo cáo khoa học: The SWI⁄SNF protein BAF60b is ubiquitinated through a signalling process involving Rac GTPase and the RING finger protein Unkempt doc
... 6B) This observation is strong evidence that UNK-fl has the ability to shuttle between the nucleus and the cytoplasm and can therefore reach its putative substrate BAF60b in the nuclear compartment ... remain uncertain On the basis of the results of a mutational analysis (Figs and S1), it appears that the RING finger of exogenously expressed Unkempt is not critically involved in the ubiquitination ... BAF60b is ubiquitinated through a process depending on Unkempt and activated Rac, the question arises of the cellular compartment where this process takes place Indeed, although Rac activation is...
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Poisoning the Well: How the EPA is Ignoring Atrazine Contamination in Surface and Drinking Water in the Central United States pot
... eliminate the use of atrazine and control weeds while reducing their use of other dangerous chemicals Poisoning the Well: How the EPA is Ignoring Atrazine Contamination in Surface and Drinking ... date with all the data from the previous 365 days, then averaging the data from the next point and the previous 365 days, and so on Hayes TB, et al 2002 Atrazine-induced hermaphroditism at 0.1 ppb ... not incorporated into the determination of the level of concern associated with the contamination in the watershed In addition, the U.S Fish and Wildlife Service criticized the model for incorrectly...
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WORKING PAPER NO. 192 IS THE EUROPEAN CENTRAL BANK (AND THE UNITED STATES FEDERAL RESERVE) PREDICTABLE? pptx
... Abstract The objective of this paper is to examine the predictability of the monetary policy decisions of the Governing Council of the ECB and the transmission of the unexpected component of the monetary ... the series of shocks change on the days of the meetings This is a good measure of how the monetary policy decisions have surprised the markets Tables 3a-3b (5a-5b) list all the surprises in the ... persistence of the surprise According to the expectation hypothesis, a surprise change in the key rates that is expected to last for the term of the bond will increase the yield on this bond by the same...
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Báo cáo khoa học: A characteristic Glu17 residue of pig carnitine palmitoyltransferase 1 is responsible for the low Km for carnitine and the low sensitivity to malonyl-CoA inhibition of the enzyme docx
... lm) Figure 3C and Table show that the IC50 values of these two single mutants were similar and that they lay between the IC50 values of the human and pig CPT1B wild-type enzymes These results ... Cloning and expression of the liver and muscle isoforms of ovine carnitine palmitoyltransferase 1: residues within the N-terminus of the muscle isoform influence the kinetic properties of the enzyme ... before (H50P and P50H) and after (H128P and P128H) TM1 and TM2 respectively (Fig 2A) These chimeras had similar specific activities (Table 1) and were expressed in P pastoris at the same level...
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Americans and Their Cars: Is the Romance on the Skids? pptx
... information on the issues, attitudes and trends shaping America and the world Survey reports are the result of the collaborative effort of the social trends staff, which consists of: About the Survey ... care of many of the other routines and amusements of daily living Here is a (slightly scary) list of things people report having done in the past year while they were behind the wheel: • More ... congestion (23%) and “other drivers” (14%) topped the list of reasons Just 3% cited the expense Among the still sizable majority who say they like to drive, the biggest reasons offered were the relaxation...
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Processing Fluency and Aesthetic Pleasure: Is Beauty in the Perceiver''''s Processing Experience? pptx
... suggested by the discrepancy-attribution hypothesis On the other hand, expectations entail an attribution to the variable that gave rise to the expectation in the first place When this variable is irrelevant ... as discussed later When the variable is relevant to the evaluation (as is the case for symmetry, prototypicality, and so on, which are characteristics of the stimulus itself), the experience is ... is unknown and fluent processing comes as a surprise On the other hand, the fluencybased affective experience is discounted as a source of relevant information when the perceiver attributes the...
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Báo cáo Y học: Nuclear proteins that bind to metal response element a (MREa) in the Wilson disease gene promoter are Ku autoantigens and the Ku-80 subunit is necessary for basal transcription of the WD gene ppt
... MREa is also the most crucial MRE for transcription of the MT gene and that there is a relationship between the distance from each MRE to the TATA box and their influence on promoter activity of the ... observed another band of 82 kDa when the MREa-protein band from the EMSA was excised from the native gel and resolved by SDS/PAGE (unpublished data) We purified the MREa-binding proteins using the avidin–biotin ... staining, the bands were sliced out of the gel and subjected to automated amino acid sequencing Construction of the IR Ku-80 gene and the truncated Ku-80 (DKu80) For the double-stranded RNAi assay, the...
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Presentation References The Time Is Now: Invest in Sexual and Reproductive Health for Young People docx
... Development www.prb.org THE TIME IS NOW: INVEST IN SEXUAL AND REPRODUCTIVE HEALTH FOR YOUNG PEOPLE Guttmacher Institute, Facts on the Sexual and Reproductive Health of Adolescent Women in the Developing ... Motherhood, accessed at http://web.unfpa.org/mothers/facts.htm Guttmacher Institute, Facts on the Sexual and Reproductive Health of Adolescent Women in the Developing World UNFPA, State of the ... in Promoting Sexual and Reproductive Health: Lessons, Research, and Programmatic Challenge, accessed at www.popcouncil.org/ pdfs/AYSRH/6.pdf THE TIME IS NOW: INVEST IN SEXUAL AND REPRODUCTIVE HEALTH...
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Cancer Research UK’s strategy 2009–2014: Cancer Research UK’s aim is to reduce the number of deaths from cancer. Our future plans are ambitious, but they are in line with the challenge and the responsibility we face. docx
... experts and organisations to understand what causes delay in diagnosis, establish the best ways of helping the public to recognise symptoms and to get them checked out by a doctor, and to understand ... knowledge and understanding of the disease that research provides and in which Cancer Research UK is leading, both in this country and internationally There is clearly much more we need to Cancer is ... survival and in preventing thousands of new cases of the disease, both in the UK and across the world Cancer Research UK has been at the heart of this progress thanks to the sustained support and...
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Federal Reserve Bank of Dallas Globalization and Monetary Policy Institute - Ultra Easy Monetary Policy and the Law of Unintended Consequences* pptx
... stimulate the real economy and reduce unemployment? It is suggested in this paper that the answer to both questions is no. a) Ultra Easy Monetary Policy and the Transmission Mechanism When the crisis ... basis in complex systems. They also conform to a Power Law linking the frequency of crises to the inverse of their magnitude. Second, predicting the timing of individual crises is impossible. Third, there is no relationship between the size of the triggering event and the magnitude of the subsequent crisis. This way of thinking helps ... Singh (2011) provides evidence of how this practice fluctuates with the credit cycle. This is consistent with the hypothesis of psychologists that most humans suffer from “disaster myopia”. This could be the result of survival strategies becoming hard wired over millions of years of evolution. ...
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Reserve Recruiting and the College Market - Is a New Educational Benefit Needed doc
... recruiting In this report, we first review - x - the evidence on the rising demand for a college education among America’s youth in general and among reservists themselves, and we ask whether the composition ... like the overall population, the demand for college among reservists is high and has increased over time We also find that the demand for college has increased throughout the AFQT distribution and, ... as the reserve components adjust to the demands of homeland security and the war on terrorism, international peacekeeping efforts, and the DoD’s desire to more fully integrate the reserve and...
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Báo cáo khoa học: A hydrophilic cation-binding protein of Arabidopsis thaliana, AtPCaP1, is localized to plasma membrane via N-myristoylation and interacts with calmodulin and the phosphatidylinositol phosphates PtdIns(3,4,5)P3 and PtdIns(3,5)P2 pptx
... Arabidopsis thaliana [12] The protein is composed of 225 amino acid residues and is rich in Glu and Lys The protein has no transmembrane domain, but is associated with the plasma membrane, and was ... determine the amount of PCaP1 in tissues and the distribution of PCaP1 in the membrane and soluble fractions (by an immunochemical method), we prepared the recombinant PCaP1 as the standard protein ... PCaP1 is unclear In this study, we focused our attention on the biochemical mechanism of the association of PCaP1 with the plasma membrane We found that the protein con2268 tains a candidate for the...
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Living Through the Hoop High School Basketball, Race, and the American Dream ppt
... sport, and may have had distant familial ties to other players These players worked together because of the appreciation they had for the rich history of success at Northeast High School and their ... thinking and thereby shapes the directives that they give the young men who compete in often racially hostile environments In the time the young men spend with the coaches, they garner and emulate the ... Bolton,” his assistant shut off the lights in the gym When the lights went out, the Raiders’ fans cheered, and then the up-tempo music began And now, your Forest County Raiders!” the public-address...
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