Bài viết Hiệu quả điều trị trúng đích trên bệnh nhân ung thư phổi không tế bào nhỏ giai đoạn muộn có và không có đột biến gen EGFR trình bày: Liệu pháp điều trị trúng đích là một liệu pháp điều trị mới, đã được chứng minh có hiệu quả cho bệnh ung thư phổi không tế bào nhỏ, đặc biệt trên nhóm bệnh nhân có đột biến gen EGFR,.... Mời các bạn cùng tham khảo.
! "#$ %&%'#%( ) *+,-.(/012#03 4 56/,-5#4(.778% 9:;=?@ABCD=6E=,?F=?AB CD=:; ?G=?AB#H#I=?JKBL?@=?6M=A 2N OPQRSTU6VW56X4YUZ2NOPQRSTU6VW5[\]^_\T`4RVW2\TW\ aUbcd\edfUgchNihNjQRfkW\lX`YhlUbcd\edfUgchNi`mUZfnfOoWW\pQR`UQ\Wq\UbcrcsW\]tbQ\cQR h\Od\uU[\vQRhwtX]Q\xZfyWtUbhhNzQQ\q`tbQ\Q\{QWqfYhtUwQR|Q}~4R\UzQWpcQ\`feQ\ RUehlbfedpQRh]XQtY9 mUlUbcd\edfUgchNihNjQRfkW\\^UQ\q`tbQ\Q\{QcQRh\Od\uU[\vQR hwtX]Q\xRU^Uf]TQ`cYQWq X[\vQRWqfYhtUwQR|Q}~ XfeQ\RUeh\PURU^QQRtbQ\[\vQRhUwQ hNUQ9_ Xh\PURU^QQRh]XQtY9 ^clUbcd\edfUgchNihNjQRfkW\Q\q` tbQ\Q\{QcQRh\O d\uU[\vQRhwtX]Q\xRU^Uf]TQ`cYQWq X[\vQRWqfYhtUwQR|Q}~7 tbQ\Q\{QcQRh\Od\uU [\vQRhwtX]Q\xRU^Uf]TQfOoWfUgchNifkW\tQR|Nl]hUQUteWfiQ\fYhtUwQ}~tQR[h\ch RUsUhNQ\hR|Q XW]NdU]Q~\UQ\QWeWfedpQRfUgchNi^c h\eQR X 1h\eQR~\UQ\Q X]eQ\_ XW^WeWQ\q` tbQ\whrcsQR\UzQWpc[\vQRR\UQ\QfOoWhNOPQR\odQX] fedpQR\]XQh]XQ^ch\eQR\]yW1h\eQRfUgchNifkW\3qc\OmQRRUs` Q\q` fYhtUwQ }~9 ]mUQ\q` fYhtUwQ}~9 3qWsUh\UbQWqQR\^h\QR[zWs_XQ\q` fYhtUwQ}~9 }Nl]hUQUtRUjd[]XUQRtbQ\Q\{QcQRh\Od\uU[\vQRhwtX]Q\xRU^Uf]TQ `cYQWqfYhtUwQR|Q}~ ?ĂÂÊ:=9Ô?ƠƯ?Đ>?ă=9Ôâê@ô=?ơưđÔê>â=9=78%B>:Ư?FƯđ>:ÔCGÔC=9đàả? ẵ#ắ6#$ ặầẩẫấ ẩậè ẻẽ éẹềè ẩểễẩ ếệầìéẩẻỉẻèậểìéẩẻỉẻĩẽ ẻíẩềèịòẩẩỏềậéịậẻíẩõóọồổỗốộ ấờìéởềịẻỡẩẩẻìộịớềèìéẩẻỉ ẻợùợỉịèệ ủớéẩũọéèặịèéẻúì ịụịẻẽẻừẩỏịửờìớẩẫữẻẻớẩủẻầẻớẩ ẩẫứìéẩẻỉẻợỉịẩữệẫõựọỳổỗỷỹýỵỹ ịớịẩẫỉ0éẻìéẩẻỉẻèẩẻứ1ẻ2éẩẽ ĩèậẻũầị3ểèẩẻứẩẽĩèậẻũỗ4ẻớịềẹ ịớị1ẻộìợ5ị1ẻớịầợẽặầề6ẫíẩ1ẻòẻớẩ ẻ ủẹệ 1ẻộìé ẩẻỉ ẻầẻ7ì ẻẽẩịớị ẩẫỉ0éẻ1ẻẻớẩẻợùẫụềèậéợậể Si^W\ãlUzQ\bá2NạQ{Q\eQ\Z2NcQRh{`4R\UzQWpc ~|Q _N]h|UQZ2NOPQRSTU\VW56X4YU }`^Ulá^Q[\^Q\8`ằ^\]]W]` 4RXằQ\Qá 4RXằfOoWW\ẳdh\cQá 7 ẩẽẩẫứẻậ5ị8ị9ỗố5ị8 ợùịòẫíẩẻúì ẩẽ ĩ ẩẫậé ịớịẻỉụé ẩẻ ịợúì ẩẫ ẻỉ ẻ6ìẩẻìẩầẻòẩẫ ềèểẩẫ ầẩủộéẩậèẩẻứ ủì9ệ ịửĩẻẻừìéẩẻỉẻề6 ẫíẩẩẻíầịẻíó õóổỗẫậéẻởé9ệ é7ợừặầặẻịợùẻớẩẻợỉịẻúìợịẻ ẻừ ẩỏĩẻ ẻịẩúệ 9é ẩẫậé ìé ẩẻỉ ẻầẩẻỡị ợặủ ẫ ợ0ịử ẻởé 8ỉị ẻệ ệẹéỡ ịịẻẽẻậểẩợ éịửịẻỡéầ 1ậ8èẩẻ0éủộéềèừéịậịẻíẩỉé ủộéịửéỉ0ĩẻỗòèịẻíẩ ịịẻẽẻậểẩ ẩẻẩặẫậủ1ủ4ủịửẩẻ ẩẻứặẽìẩộ ẻớẩẩẫứĩứìệ2 ầ8ẫệéẫậ!ẩẻ "ịẩậẫ ẫịẩậẫ é#ệ é"ẩĩ ềè ẫậẩĩầ ợỉịéèìẻớợúìẩẫ ẩẫỡéợịẻỗếẻúì éẻấị ìợùịẻ éệẻệộấờìịẻ5ẩ ịẻ$éởợ ẩĩẽé ềẹệ ịợ ợớ éẩẻìộịịử1ẻộìẩẫậéìẻớợúìẩẫ ẩẫỡéợịẻỗ4ẻậ%éóỹýỳỹ ĩẻẻừìé 234356789 " #$% &'( )*+,' -./01 *$)'234,' 56785.9:(3';?@A.01 *$)''+BCD /: 'E' "F, 3$' ; / A$GH.CI' JK$ LM.0$NL FO0P. QR,0/*S' ' T'L'( " #$% &'( ) *+, ' - C:'( 01 *$)' (3' ; U'(0A"V'( M JK$ LM.0$NL FO 0P. WXY?ZLB ' $E'Q I$[$S \:C : / ' $NL'( $E'.VLJN $SL]L^.9:G$SL" A" 0$NL FO F_'(0P. FE'*S' ' T'L'( " #$ % &'( )*+,' -($:$0,I'CL1'?`,0/Q0N +$'( $E'.VL0 a. H. $S'JK$Cb. $ELc 5?dA' ($A eGS0A"V'( ,+'*1fg>>h JK$0$NL FO0P. 2 :$' /C *S' ' T'L'( " #$% &'( )*+,' -($:$0,I'CL1'./ J+% &'(./01 *$)'(3';? 8?dA' ($A U$($:'iM'(*S' % &'( $)' F$j'fk=lhJ+ U$($:'iM'( ,+'*1fglhi:L 0$NL FO0P. 2' /C *S' ' T'L'( " #$ % &'( )*+,' -($:$0,I'CL1'./J+% &'( /01 *$)'(3';? mnopqrsptu vmwxyz{y|}wx~| $)'.VLQC& ^ G,I FU'( a"Q./ 3, R$R. U$($:' iM'( EC? mnxz|} 6*S' ' T'L'( " #$% &'( )*+, ' - ($:$0,I' [ a 0$NL FO*'( I$*S' J$E':,J+*S' k #$ZFL'( '(Q*S' J$S' ZFL'( '(Q*S' J$S' L\( OJ+*S' J$S'I. :$?S' ' T' a '0,A'4A.0O' RH:J+,%) ]L^C& *S' .J+% &'(C.L'( '+,% A.? @A.CLC&L'( " #$0_. F,'(":F:$'Q a.G+C 4 '( $SC ¡C 01 *$)'(3'; I$ FL'( TC '( $E' VL >QgJ3F:GG>3i",'i3 >: 3h0 a. P' *'( #'(.9: eGS0A"V'( ,+' ,+'f@>hJ+ eGS 0A"V'(C1 " ơ' fk>h? *>R'YU!.Z-?YX !#$%!&'()!*+, >4-?>@ 9!5A-?%BC .< D4;)7!.E-?!*- -./-#*0%!12#3).).4#+-5.* 6-.-.4-?;)7!.E-?!*-)%F*)G-?!14-?!1HI-?.J, K9!!.L48M*.4N)5+!!.()-?.*C-)O%P 5+!!.()-?.*C-)O%P [\]^_`ab]c^dbefg]ehi]^ecjfkclmnoph]fqmrs adtu vwkcfiexy]^ z{{| }.E-?)7!1*6%).O-?1M1D-?)~R 6-.;5.--?.4!#T-?K- {| }.--?.4!#T-? @-.!.HI-?;!1*6%).O-? 6-.!F*!.*:% {| }.--?.4!#T-? @-.!.HI-?-.H-?,.*)F? -?P7KN!)~R!1*6%).O-? 6- E-?)75.--?.4!#T-? @-.!.HI-?.4N)'DK >*6)-.H-?)-!,.)>!F* {| } !.*:%#HJ) {| $-)7S?*(,#)$-!.*+!>D#HJ)).KS7)B!+ {| $-)7S!1J?*(,19!'->D#HJ)).KS7)B!+!.HI-?%BC{| }.E-?!,.)>!F*!.*:%;)$-)7S!1J?*(,'*C-!)>D#HJ)).KS7)#N) *C! {| *6!?*HI-?;-K>*6 .H-?).HR)7-?%B)!=>4-? {| 6-.-N-?).KS7)#N) *6! 6-.>*6z{| 9,.F* {| =>4-? [\]^`dkc]xb]c^dbxbw]^eckectecjfĂÂÊÔƠ [Đ]cxb cƯ]^mnxb]c^db w]^cfg ] efg]Ơ ơHI-?53-.'F*%#3) -.9!)~R5.F*%!1C- } * +-K9! .4N)ưđ-?) -?#T).9!). 1>0 @- #*:K%-?!.HUàảY !.HI-? ã-!.H-? *+-K9! !.O,.Z! 4D-!4D1 dkc]xb]c^dbxbw]^eckect [Đ]cxbw]^ [Đ]c]^â]^ [Đ]cedê]ehdt] uyecă]Ơ edê]ehdt]ĂôƠ ôƠ K±{| -?°{|S4 Q*K°{|S4 Q* >*!1H)#*0%!12 4±N){!|-? >*!1H)#*0%!12 }.E-?!-?U-.H-?).HR!1>0 *+,!)!-? -?H-? @-.!.HI-?Y ạ%9!.*6-!.CK -!*8R*8á-?-.H-?5.E-?%9! KT 4N)-.*0% *6-!.CK!ã-!.H-?K* !ã-!! H?K* 2343561789 9 !"$"%&'()*+,)-./0.1023& 45&$ 0E2}&$0j&$~L4B& & I&2tLz4B& *"B& 7&$6 869%6:%&; & 4+e2>J&$4&${?E{4B& & I& -./0O80-& 0E-j24"y&$=&( 2>J&$ O=F:+0EP&$ Q%2R&$AS? TUVWXY Z[\]^ZYX_`a$ "S& 0bc 2cI& A R"c*+zz4B& & I&A&$0E-j24"y&$=& 2D -de -D 080 &$ceS& 2f0 -gJ -b0 2>J&$ &+e 4&$ z?lj 2c}"2>c&$ 4 & 0c&$ :+ wMxwMw? :B&26 7&&%F0w &$ "S& 0bc e h0-./0ij"-k&$ -gJ -b0 F 0E*+A &$0E-j24"y&(?9 &$ 2>J&$&$ "S&0bceG"& >.!&$lg" h0mi+ &E 22cR0J0-|&$.&$ 22cR0xL&F aj"6 SnceB2? 0"yF 2:B0%J 7&0w& EF 0E:HnJ-% GR0804B& & I&-|0%J2c}"?0"&JF2cey& %>0"&JF*e %>0"&JF2y4+J:1& \_Z[âZêôơư wMxwMw \đâư âZêư \đâư âZêààư zNNMwạ {Nz{M~¹ xuNwM~¹ xzMw¹ wNuMx¹ x~zLMu¹ wN{xM{¹ NN~M¹ ~wwMw¹ w~M~¹ x{~M¹ wxMz¹ ~LxLL¹ L L {xLL¹ L L zzxLL¹ L L :B-j24"y&$=&(2>J&$cd&2&$ "S&0bc:+zNạ {v~LM2>J&$-E0 Deyc:+-j2 4"y&ặ-j24"y&OE%-Jg&-"& & A &$:+F:B0 A c&$n0 F|=OJ&xu0"yFNNMạ *+-j24"y&-"F ~N~=OJ&wx0 "yF {~Muạ?a$J+">%0ầ&6 82 "B&Fj2GR-j24"y&0E &$ Q%A 80*1"2:B26 7&& -j24"y&-"Fxu)=OJ&x~wM~¹*+-j24"y&OE%-Jg& A &$-"& & =OJ&xuwM~¹?9 &$6 82 "B&2>.!&$ /6&+JF%&$-j24"y&$IeA 8&$ 9ÈG4&$z? 234356789 !"#$%&'() *+,-.!/-0'12&!"3!456 7!/'89!"-0'12&! 4*:!-0'12&! ;?!"@!">A2BCD EFGIJKLMNOPQRS TTUVWQXXYS EFGIJKLMNOPQZS [\UVWQTXYS EFGIJKL]PM^ _` aWU[\QXXb\YS EFGIJKL]VXVP a_ _TU[\Q[Vb`YS EFGIJKLNc_`d _V _U[\QabVYS EFGIJKLefghijLklmLnhJoLlpLl _` _U[\QabVYS EqJrsJhtu vLn Glwx GlobLnlJyL xvz xaGlJhJogzhJzG~LyzG~yLQ[GltLn klmLn nlJLl{L h|}xG~|Ln l}u Li htu PP_b[[Ă`XYÂWb\_Rab_ar\GltLnPP vLnliLGiLgz[GltLnlix\GltLnhJz TĂ`XYÂR_bT`R_Tbc[SƠyLxjLlhfbnlJ G~hxlfezl|sLnnJGhtuvLnGiL Ll{LxtxhtuvLnGiLG~jLnxƯgILlLlĐL IF PP Llf hFGIJKL MNOP QRSi rsJ xliGlăxlâqêg~LiôkÔLhLlUGơLngzW[ Llf hFGIJKLMNOPQZSPPgzW[GltLn GltLnrW\GltLnhJzG~Llf hFGIJKL rW\GltLnLlf hFGIJKLMNOPQZSL MNOPQZSL|}G\`bTTY rVWY irsJ |}G[[b[[Y raWY irsJLlf hFGIJKL Llf hFGIJKLMNOP QRSXabacY rTWYb MNOPQRSaXY rXY QILnXSzLlJyLb xliGlăxlJzl|sLnxJGlJLGiLG~jLnr wxlyLlxlLklmLnxfLnlgGlqLnky xưLơLnGqGlưLLlfxfhFGIJKLMNOPQZS !"đ$=,+,-+!"'/,'/B'/3:64;D ;)'/+!" ;)'/+!" :92-+!" 456BDQL[\S 456BDQLTTS 456BDQLaWS 456BDQLaWS P W W W W P _aU[\Q[[b[[YS UTTQaXYS WTUaWQaWYS W_UaWQXYS d _XU[\QT_b\cYS _TUTTQ[_bVaYS _TUaWQcWYS _TUaWQcWYS W`U[\QaXYS _`UTTQT[b_VYS WaUaWQ_WYS WXUaWQaXYS _UaWQXYS PPPZP _aU[\Q[[b[[YS UTTQaXYS TUaWQaWYS PP_b[[Ă`XYÂWb\_Êab_a PPTĂ`XYÂR_bTV\Ê_Tbc[ QPhtuvLnliLGiLĂPhtuvLnFGulLĂdILlÔLhLlĂILlGJKLG~JoLĂPP htuvLnGiLIFS 12 34546789 21 !"#$%&'(')(*+ !,- ,/0 !1,23-'245678/-95:;< @8AB,2( ! @8A",2( ! >-0?)(*+ ! CDE1F