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NEW MECHANISM EXPLAINING FLUID OVERLOAD IN PATIENT WITH DIASTOLIC HEART FAILURE OR HEART FAILURE PATIENT WITH PRESERVED EJECTION FRACTION : WHEN THE VEINS CAUSE HYPERTENSION IN THE ARTERY Presenter : Dinh Tran Xuan Truong OUTLINE 1.BACKGROUND 2.METHODS 3.RESULT 4.CONCLUSION BACKGROUND Heart failure (HF) Structural and functional impairment Ejection of blood Ventricular filling HFpEF BACKGROUND Intravascular (mainly venous) compartment Extravascular compartment FLUID OVERLOAD METHODS CHOOSE SAMPLE Time : From January 2015 to April 2016 Number of patient : 25 patients Dx : HFpEF CLASSIFY THE PATIENTS Location of fluid overload depending on SEFV test Present with pulmonary HTN or prediction of future pulmonary HTN STATISTICAL ANALYSIS: Fisher’s exact test for categorical variables Two-sample t-test for continuous variables METHODS METHODS METHODS 13% More elastic 65% More compliant METHODS METHODS Normal Person 𝑅𝐶 1<