asthma, mechanisms and protocols

[...]... Zealand Arch Dis Child 61, 6–10 19 Crane, J., Pearce, N., and Flatt, A E A (1989) Prescribed fenoterol and death from asthma in New Zealand, 1981–83: case-control study Lancet i, 917–922 20 Mcnicol, K N., Macnicol, K N., and Williams, H B (1973) Spectrum of asthma in children I Clinical and physiological components Br Med J 4, 7–11 21 Williams, H and Mcnicol, K N (1969) Prevalence, natural history, and. .. hyperreactivity and asthma in relation to environmental factors Arch Dis Child 63, 473–478 8 Yemaneberhan, H., Bekele, Z., Venn, A., Lewis, S., Parry, E., and Britton, J (1997) Prevalence of wheeze and asthma and relation to atopy in urban and rural Ethiopia Lancet 350, 85–90 9 Shaheen, S O., Aaby, P., Hall, A J., Barker, D J., Heyes, C B., Shiell, A W., and Goudiaby, A (1996) Measles and atopy in Guinea-Bissau... of wheezy bronchitis and asthma in children An epidemiological study Br Med J 4, 321–325 22 Strachan, D P., Butland, B K., and Anderson, H R (1996) Incidence and prognosis of asthma and wheezing illness from early childhood to age 33 in a national British cohort Br Med J 312, 1195–1199 23 Roorda, R J., Gerritsen, J., van Aalderen, W M., Schouten, J P., Veltman, J C., Weiss, S T., and Knol, K (1993) Risk... of the bronchi in normal subjects, in status asthmaticus, in chronic bronchitis, and in emphysema Thorax 24, 176–179 48 Takizawa, T and Thurlbeck, W M (1971) Muscle and mucous gland size in the major bronchi of patients with chronic bronchitis, asthma, and asthmatic bronchitis Am Rev Respir Dis 104, 331–336 49 Heard, B E and Hossain, S (1972) Hyperplasia of bronchial muscle in asthma J Pathol 110, 319–331... Membrane-bound and soluble alpha IL-5 receptor mRNA in the bronchial mucosa of atopic and nonatopic asthmatics Am J Respir Crit Care Med 155, 1413–1418 Clutterbuck, E J., Hirst, E M., and Sanderson, C J (1989) Human interleukin-5 (IL-5) regulates the production of eosinophils in human bone marrow cultures: comparison and interaction with IL-1, IL-3, IL-6 and GM-CSF Blood 73, 1504–1512 Lopez, A F., Sanderson,... need to understand the nature of airway EC differentiation and how it is regulated To achieve these goals, progress has been made in culturing differentiated airway ECs from human tissues in a well-defined culture environment (4,5), From: Methods in Molecular Medicine, vol 44: Asthma: Mechanisms and Protocols Edited by: K F Chung and I Adcock © Humana Press Inc., Totowa, NJ 31 32 Wu and for mucin quantitation... regarded as occurring prior to the development of asthma, and therefore this has been taken to mean that exposure to these allergens causes asthma Thus, the degree Asthma: Cell and Molecular Biology 13 Fig 3 Interactions between environmental and genetic factors in the induction of chronic inflammation in asthma, leading to airway hyperresponsiveness and narrowing, which underlie the clinical presentation... P K., Wardlaw, A J., Nelson, F C., Collins, J V., and Kay, A B (1989) Bronchial biopsies in asthma:an ultrastructural, quantiative study and correlation with hyperreactivity Am Rev Respir Dis 140, 1745–1753 46 Glynn, A A and Michaels, L (1960) Bronchial biopsy in chronic bronchitis and asthma Thorax 15, 142–153 47 Dunnill, M S., Massarella, G R., and Anderson, J A (1969) Comparison of the quantitative... pathway include PGs and thromboxane PGD2 and PGF2α, and thromboxane may facilitate the release of acetylcholine from cholinergic nerves, to augment bronchoconstriction (119–121) PGE2, on the other hand, may have antibronchoconstrictor properties, and protects against exercise- and allergen-induced bronchoconstriction (122,123) Neuropeptides, such as sub- Asthma: Cell and Molecular Biology 11 Fig 2 Release... 18 Chung and Adcock 10 Shirakawa, T., Enomoto, T., Shimazu, S., and Hopkin, J M (1997) Inverse association between tuberculin responses and atopic disorder Science 275, 77–79 11 Demissie, K., Ernst, P., Gray Donald, K., and Joseph, L (1996) Usual dietary salt intake and asthma in children: a case-control study Thorax 51, 59–63 12 Keating, G., Mitchell, E A., Jackson, R., Beaglehole, R., and Rea, H . history, and rela- tionship of wheezy bronchitis and asthma in children. An epidemiological study. Br. Med. J. 4, 321–325. 22. Strachan, D. P., Butland, B. K., and Anderson, H. R. (1996) Incidence and. actuation normal T-cell expressed and Asthma: Cell and Molecular Biology 7 secreted (RANTES), IL-8, eotaxin, and macrophage chemoattractant protein-1 (MCP-1) and -3, and granulocyte-macrophage colony-stimulating. y0 w1 h1" alt="" Asthma: Cell and Molecular Biology 1 1 1 From: Methods in Molecular Medicine, vol. 44: Asthma: Mechanisms and Protocols Edited by: K. F. Chung and I. Adcock © Humana Press Inc.,