Eukaryotic Translational and Post translational Gene Regulation

... modification can alter gene expression in many ways Describe how phosphorylation of proteins can alter gene expression 3/4 Eukaryotic Translational and Post -translational Gene Regulation Because ... degraded ([link]) One way to control gene expression, therefore, is to alter the longevity of the protein 2/4 Eukaryotic Translational and Post -translational Gene...

Ngày tải lên: 30/10/2017, 23:53

... The interplay between viral and cellular SR proteins certainly has a substantial effect on post- Table Functional interplay between viral proteins and cellular SR proteins as well as SR kinases ... Therefore, SR proteins, together with other RNA-binding proteins, coordinate the coupling of splicing and polyadenylation Viral and cellular SR pr...

Ngày tải lên: 23/03/2014, 06:20

... Eukaryotic Post- transcriptional Gene Regulation regulation, with the frequency of different splicing alternatives controlled ... evolve without eliminating the original, functional protein Link to Learning 2/5 Eukaryotic Post- transcriptional Gene Regulation Visualize how mRNA splicing happens by watching the process in action ... proteins at the 5' or 3' UTR influences the...

Ngày tải lên: 30/10/2017, 22:32

... 1169–1178 ª 2005 FEBS Characterization of Drosophila Met gene product of pBluescript II (Stratagene), and the identity of the cDNA clone was confirmed by sequencing Binding assay The DCC assay was ... sequence Therefore, it is reasonable to consider that the GAL4–DBD fusion of MET sits on the UAS of the reporter construct even in the absence of ligand, an...

Ngày tải lên: 16/03/2014, 18:20

... regions Their findings suggest that several factors, including both specific DNA sequences and epigenetics, are involved in controlling meiotic recombination in humans Nutritional influences during ... before and during pregnancy may affect the establishment of CpG methylation and the life-long expression of metastable epialleles (epigenetically modified alleles) in human...

Ngày tải lên: 14/08/2014, 17:22

... Cy3 Cy5 gel2 Cy5 gel3 Cy3 Cy5 gel4 Cy5 Cy3 Cy2 Cy5 Cy2 Cy2 Cy3 Cy2 Cy2 gel5 Cy3 gel6 Cy3 Cy5 Cy2 gel7 Cy5 Cy3 Cy2 Cy5 Cy2 gel8 Figure Cy3 Each two-dimensional gel was loaded with 50 μg of a Cy3-labeled ... falciparum schizont-stage proteins (a) Protein reference pool (internal standard) labeled with Cy2 (b) Overlay of images showing Cy3-labeled and Cy5-labeled parasite proteins from tim...

Ngày tải lên: 14/08/2014, 21:20

... II complex S2 Serine of yeast RNA polymerase II C-terminal domain S2-P Phosphorylated serine of yeast RNA polymerase II C-terminal domain S5 Serine of yeast RNA polymerase II C-terminal domain ... study the RNAPII modifications on both the CTD and the globular core of the enzyme in the presence and absence of Rtr1 IV Mechanisms for RNAPII de...

Ngày tải lên: 24/08/2014, 09:44

... 7.3) 20 mM CaCl2 20 0 mM CaCl2 20 mM MgCl2 20 0 mM MgCl2 Thermofluor 50 mM Hepes (pH 7.5) 150 mM NaCl 20 mM CaCl2 20 0 mM CaCl2 20 mM MgCl2 20 0 mM MgCl2 50 mM NaPO4 (pH 7.5) 150 mM NaCl 20 mM CaCl2 20 0 ... the stability and oligomeric state of CRMP -2, and a number of different post-translationally modified isoforms of CRMP -2 could be identified in the brain Our data, i...

Ngày tải lên: 16/03/2014, 06:20

... retinoic acid (RA) treatments on GnRH II promoter activity To investigate the in vivo effect of RARa and RXR on the transcriptional regulation of the hGnRH II gene, the expression vector of human ... on the promoter activity of the hGnRH II gene in TE671 and JEG-3 cells In vivo effect of RARa and RXRa with their ligands, ATRA and 9-...

Ngày tải lên: 16/03/2014, 10:20

... [104,105] and in S cerevisiae [88] have lead to a profound understanding of how DNA binding, inducer binding and dimerization function in TetR This informa- Gene regulation by tetracyclines (Eur ... concentrations of tc for full induction [15] These conflicting requirements are met by the genetic organization of the resistance determinants (reviewed in [6]) and...

Ngày tải lên: 23/03/2014, 21:20

... Interestingly, yeast growing in a colony undergoes cyclic changes in metabolism, from acidic to alkaline [46] Furthermore, alkali-producing colonies can entrain colonies in the acidic phase and ... involving oscillations and cycles, which are diffused in all disciplines of natural (and not only) sciences In biological studies over recent decades, it has become more and more c...

Ngày tải lên: 30/03/2014, 04:20

... induction of the major immediate early enhancer of human cytomegalovirus by cyclic AMP J Gen Virol 71, 105–113 12 Meier, J.L & Stinski, M.F (1996) Regulation of cytomegalovirus immediate early genes ... factors and proteins related to the proliferation/differentiation of cells [39,40] To examine the effects of LPS and CpG-ODNs in cells that harbor a CMV promoter and to...

Ngày tải lên: 30/03/2014, 13:20

... [32] Figure Gene expression analysis of MPD neutrophils Gene expression analysis of MPD neutrophils Gene expression of neutrophils from MPD patients, healthy subject neutrophils and healthy subjects ... the molecular basis of MPDs, we compared gene and miRNA expression profiles of neutrophils from MPD patients with those from healthy subjects We...

Ngày tải lên: 18/06/2014, 15:20