Analysis of transcription factors in living human cells with

Analysis of transcription factors in living human cells with the help of split ubiquitin system

... the split- ubiquitin system The main objective of this analysis is to demonstrate the feasibility of the split- ubiquitin system to detect interactions between human proteins inside human cells and ... linker histone hH1 with the other core histone proteins, hH2A, hH2B, hH3 and hH4 have been analyzed inside human HT1080HPRT- cells with the help of...

Ngày tải lên : 29/09/2015, 13:01

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Tài liệu Báo cáo khoa học: Roles of AP-2 transcription factors in the regulation of cartilage and skeletal development doc

... role of AP-2a and AP-2e in chondrogenesis Overview of the differentiation stages during chondrogenesis and the involvement of transcription factors (henatoxylin and eosin-stained section of an ... analyses of the regulation of AP-2 and the interactions of the transcription factor with binding partners, as well as of the regulation of target...

Ngày tải lên : 16/02/2014, 09:20

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Tài liệu Báo cáo khoa học: Characterization of the promoter for the mouse a3 integrin gene Involvement of the Ets-family of transcription factors in the promoter activity doc

... within )260/)119, we Ó FEBS 2002 Integrin a3 gene promoter (Eur J Biochem 269) 4529 Fig Eﬀects of mutations in the Ets- and GATA-binding sites and the E-box of the mouse a3 integrin gene on promoter ... assay (EMSA) using the Ets consensus site at )133 As the involvement of the Ets consensus binding site at )133 in the promoter activity of th...

Ngày tải lên : 21/02/2014, 03:20

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báo cáo khoa học: " Roles of arabidopsis WRKY18, WRKY40 and WRKY60 transcription factors in plant responses to abscisic acid and abiotic stress" doc

... WRKY40 and WRKY60 proteins indeed function in a complex pattern in plant responses to ABA and abiotic stresses The complex roles of the three WRKY transcription factors in plant biotic and abiotic ... al.: Roles of arabidopsis WRKY18, WRKY40 and WRKY60 transcription factors in plant responses to abscisic acid and abiotic st...

Ngày tải lên : 11/08/2014, 11:21

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Báo cáo y học: "Oxygen-sensing mechanisms and the regulation of redox-responsive transcription factors in development and pathophysiology" ppsx

... that feeds into the biosynthetic machinery, allowing the formation of glutathione (GSH) by the action of the rate-limiting enzyme, γ-glutamylcysteine synthetase (γGCS) The activity of γ-GCS is ... discussion of the regulation of oxygen-sensing mechanisms The regulation of oxygen sensing mechanisms Oxygen sensing and its underlying molecular stratagems have...

Ngày tải lên : 12/08/2014, 18:20

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Báo cáo y học: "Science review: Redox and oxygen-sensitive transcription factors in the regulation of oxidant-mediated lung injury: κ role for nuclear factor-κ" pdf

... into the lungs and to increased pulmonary proinflammatory cytokine expression [7] However, the initial events induced by hyperoxia, thereby leading to acute inflammatory lung injury, remain incompletely ... [26–37] In a murine hyperoxia model, the effects of lisofylline on the activation of NF-κB and CREB, on the expression of proinflammatory cytokines in the lungs...

Ngày tải lên : 12/08/2014, 19:21

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Báo cáo y học: "Science review: Redox and oxygen-sensitive transcription factors in the regulation of oxidant-mediated lung injury: α role for hypoxia-inducible factor-1α" pptx

... required for the expression of many cytokines involved in the pathogenesis of acute lung injury [26–35] In acute lung injury caused by infection of bacteria, cytokine receptors HIF-1 consists of two ... function play a central role in initiating the innate immune system and in activating NF-κB Anti-inflammatory cytokines have the ability to suppress inflammat...

Ngày tải lên : 12/08/2014, 19:21

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Báo cáo y học: "Expression of hepatocytic- and biliary-specific transcription factors in regenerating bile ducts during hepatocyte-to-biliary epithelial cell transdifferentiation" docx

... bile ducts [17-19] In the present study, the expression of hepatocyte- and biliary-specific HNFs is examined during reprogramming of cell lineage during transdifferentiation using DAPM + BDL and ... followed by incubation with pertinent primary antibody overnight at 4°C The primary antibody was then linked to biotinylated secondary antibody followed by routine avidin-bio...

Ngày tải lên : 13/08/2014, 13:20

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Báo cáo y học: "Genome-wide identification of novel expression signatures reveal distinct patterns and prevalence of binding motifs for p53, nuclear factor-κB and other signal transcription factors in head and neck squamous cell carcinoma" docx

... regulatory modules including TBPF (TATA -binding protein factors) , ECAT (enhancer of CCAAT binding factors) , or PCAT (promoter of CCAAT binding factors) p53 binding motifs were also displayed '(+)' and ... genotype and protein expression in UM-SCC cell lines p53 genotype and protein expression in UM-SCC cell lines (a) The p53 genotype of ten University o...

Ngày tải lên : 14/08/2014, 07:21

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Báo cáo y học: " Regulatory module network of basic/helix-loop-helix transcription factors in mouse brai" doc

... bHLH regulatory TF network in mouse brain The bHLH regulatory TF network in mouse brain The graph depicts the inferred regulatory network of bHLH TFs (yellow ellipses) and their target genes (pink ... have constructed a transcriptional regulatory network of bHLH TFs in mouse brain using microarray data (gene expression profiles) and the module network metho...

Ngày tải lên : 14/08/2014, 08:20

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The role of kruppel like factors in embryonic stem cells

... transcripts zinc finger protein 42 zinc finger protein 143 zinc finger protein of the cerebellum XI Introduction CHAPTER I INTRODUCTION Introduction CHAPTER I INTRODUCTION Stem cells can be identified ... MEF feeders in the presence of serum The conditioned medium can support the normal growth of ES cells in the absence of feeders indicating that fibroblasts are pr...

Ngày tải lên : 14/09/2015, 14:07

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Tài liệu Báo cáo khoa học: Altered deoxyribonucleotide pools in T-lymphoblastoid cells expressing the multisubstrate nucleoside kinase of Drosophila melanogaster doc

... differences in RNA or protein synthesis between the Dm-dNK expressing cells and their corresponding parental cell lines, the incorporation of dCyd was increased in the Dm-dNK expressing cells (by 1.6-fold ... gene expressing cells than into DNA of the parental B Fig Mitochondrial DNA (mtDNA) in H9 cells overexpressing Drosophila melanogaster nucleoside k...

Ngày tải lên : 20/02/2014, 01:20

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Báo cáo khoa học: NrpRII mediates contacts between NrpRI and general transcription factors in the archaeon ¨ Methanosarcina mazei Go1 pot

... to the NrpRI ⁄ NrpRII complex decreases the binding afﬁnity of NrpRI to the operator as well as decreasing the NrpRII binding afﬁnity to the general transcription factors, potentially by inducing ... Role of NrpRII in M mazei K Weidenbach et al 2-Oxoglutarate directly affects NrpRI binding to the operator and NrpRII binding to the general transcriptio...

Ngày tải lên : 29/03/2014, 21:20

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Báo cáo hóa học: " Outage Analysis of Ultra-Wideband System in Lognormal Multipath Fading and Square-Shaped Cellular " ppt

... Spain, September 2004 [9] P Pirinen, “Ultra wideband system outage studies in a square cell with partial rake receiver and lognormal fading, ” in Proceedings of IEEE International Conference on Ultra-Wideband ... “Performance of RAKE reception for ultra wideband signals in a lognormalfading channel,” in Proceedings of International Workshop on Ultra Wideband Systems (...

Ngày tải lên : 22/06/2014, 22:20

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