Suitability of insulin like growth factor 1 (IGF1) as a measure of relative growth rates in lingcod

... ARTICLE Suitability of Insulin- Like Growth Factor (IGF1) as a Measure of Relative Growth Rates in Lingcod Kelly S Andrews* and Brian R Beckman National Oceanic and Atmospheric Administration–Fisheries, ... body growth for lingcod Ophiodon elongatus using plasma insulin- like growth factor (IGF1) with the ultimate goal of measuring spatial dif...

Ngày tải lên: 04/09/2015, 17:15

... presence of four families of type II transmembrane serine proteinase [30] The matriptase subfamily constitutes three members (matriptase, matriptase and matriptase 3) It is conceivable that some of ... analyses of purified matriptase Soluble matriptase was purified from the conditioned medium of DLD-1 cells as described in the text The purified matriptase (approximate...

Ngày tải lên: 19/02/2014, 07:20

... degradation of IGFBP-1 isoforms The y-axis shows the percentage of the ratio between the spot area of the degraded and that of the untreated protein measured using IMAGE J 1.37V software the presence of ... almost to the same extent as the unmodified protein and that the susceptibility to proteolytic degradation of the isoforms increased with the...

Ngày tải lên: 07/03/2014, 00:20

... high-af®nity binding proteins (IGFBPs) with  10 -fold higher af®nity than their binding to IGF receptors IGFBPs thereby in¯uence the availability of IGF to bind to IGF receptors [12 ] Over the past 14 years, ... analogue binding to highanity recombinant IGF1 R Binding of IGF- II (A), des- (1 6) -IGF- II (B) and Arg6 -IGF- II (C) to rhIGF1R measure...

Ngày tải lên: 08/03/2014, 22:20

... Effects of inhibitor treatment (wortmannin and U0126) on insulin ⁄ IGF-1-induced phosphorylation of PI3K ⁄ Akt ⁄ mTOR-dependent signaling in C2C12 myotubes Fig S2 Complex formation of TSC1 and TSC2 ... versus control group (P < 0.05) Phosphorylation of Akt and S6K1 was induced within 10 min, and was maintained for at least 60 Altered distributions of TSC1 an...

Ngày tải lên: 15/03/2014, 11:20

... hyperinsulinemic hypoglycaemia Chang Gung Med J 2008, 31: 107 -11 doi :10 .11 86 /14 79-5876-8 -11 7 Cite this article as: Pantaleo et al.: The emerging role of insulin-like growth factor receptor (IGF1r) ... WT: Insulin-like Pantaleo et al Journal of Translational Medicine 2 010 , 8 :11 7 http://www.translational-medicine.com/content/8 /1/ 117 Page of growth facto...

Ngày tải lên: 18/06/2014, 16:20

... H: Cytokines and bone loss in a 5-year longitudinal study — hormone replacement therapy suppresses serum soluble interleukin-6 receptor and increases interleukin- 1receptor antagonist: the Danish ... Baylink DJ, af Ekenstam E, Lindh E, Mohan S, Ljunghall S: Circulating levels of insulin-like growth factor- I and -II, and IGF- binding protein-3 in inflammation...

Ngày tải lên: 09/08/2014, 01:21

... (IGF) -1 to IGF -binding proteins, on 12 5I-labeledinsulinbinding NBI- 317 72, a small-molecule inhibitor like growth factor (IGF) -1 to IGF -binding proteins, on 12 5I-labeled IGF -1 binding to human osteoarthritic ... – 0 .1 10 10 mary cultured factor (IGF) -1 to IGF -binding proteins (IGFBPs), in insulin-like of NBI- 317 72, a small-molecule inhibit...

Ngày tải lên: 09/08/2014, 01:23

... this article as: Jones et al.: Comparison of Radioimmuno and Carbon Nanotube Field-Effect Transistor Assays for Measuring InsulinLike Growth Factor-1 in a Preclinical Model of Human Breast Cancer ... conditions in the University of Maryland, Baltimore animal facility and maintained in accordance with institutional guidelines approved by the Univ...

Ngày tải lên: 11/08/2014, 00:23

... cytokine- inducible SH2-containing protein, suppressors of cytokine signaling- 2 and suppressors of cytokine signaling3 Bars represent the mean expression of mRNA of cytokine- inducible SH2-containing ... activation of cytokines We therefore measured the serum concentrations of a pleiotropic cytokine (IL-6) and an anti-inflammatory (IL-10) cytokine and...

Ngày tải lên: 13/08/2014, 08:20

... before and after cultivation for days Values are the means and standard errors of the mean (n = 6) other tissues also secrete this peptide at a lower level [20–22] The predominant secretion of 8K-BLP ... than to those of bombyxin and insulin, which are of the order of 100 pm [23,24] The very high titer of 8K-BLP may be due to a remarkably high level of gene expressio...

Ngày tải lên: 18/02/2014, 13:20

... skeletal myotube hypertrophy FEBS Journal 273 (2006) 3709–37 21 ª 2006 The Authors Journal compilation ª 2006 FEBS 3 719 Insulin-like growth factor signaling 14 15 16 17 18 19 20 21 22 23 24 25 A ... that Neu2 expression is dependent on AKT activation during IGF -1- induced differentiation of myoblasts Neu2 expression is strictly dependent on IGF -1 signaling To...

Ngày tải lên: 19/02/2014, 06:20

... (IGF1R): Insulin-like Growth Factor- 1 receptor; (IGFBP-3): Insulin-like Growth Factor Binding Protein-3; (IGFBP-4): Insulin-like Growth Factor Binding; Protein-4; (MAPK): Mitogen-activated protein kinase; ... role of secreting IGFBPs in melanoma However, data not support the clinical utility of measuring levels of IGFBP-3 and -4 in sera of melan...

Ngày tải lên: 18/06/2014, 15:20

... Insulin-like growth factor-I peptides act centrally to decrease depression-like behavior of mice treated intraperitoneally with lipopolysaccharide Sook-Eun Park1,2,4, ... response to activation of the innate immune system [1-3] Exposure of volunteers to a low dose of endotoxin induces depressed mood that correlated with cytokine expression, independen...

Ngày tải lên: 19/06/2014, 22:20

... 1. 1 Nhân tố tăng trƣởng hIGF- 1 1. 1 .1 Giới thiệu 1. 1.2 Đặc điểm gene mã hóa cấu trúc phân tử protein hIGF- 1 1. 1.3 Đặc điểm hoạt động hIGF- 1 1. 1.4 Chức hIGF- 1 ... hành nghiên cứu sản xuất protein hIGF- 1 công nghệ DNA tái tổ hợp Trong khuôn khổ chương trình nghiên cứu, luận văn thực nhằm: Nghiên cứu tạo dòng, biểu thu nhận hIGF- 1 (human...

Ngày tải lên: 25/07/2014, 08:29