molecular aspects of insulin like growth factor binding proteins

... RG (1997) Identification of a family of low-affinity insulin- like growth factor binding proteins (IGFBPs): characterization of connective tissue growth factor as a member of the IGFBP superfamily ... H & Miyazaki K (1996) Synergistic growth stimulation of mouse fibroblasts by tumor-derived adhesion factor with insulin- like growth factors and insulin Cell Growth Differ 7, 1671–1677 10 Ahmed ... insulin- like growth factor binding protein-3 protease J Endocrinol 142, 407–415 Fowlkes JL, Serra DM, Bunn RC, Thrailkill KM, Enghild JJ & Nagase H (2003) Regulation of insulinlike growth factor- 1...

Ngày tải lên: 19/02/2014, 07:20

... Insulin- like Growth Factor; (IGF1R): Insulin- like Growth Factor- 1 receptor; (IGFBP-3): Insulin- like Growth Factor Binding Protein-3; (IGFBP-4): Insulin- like Growth Factor Binding; Protein-4; (MAPK): Mitogen-activated ... Perloff M, Malone WF, Formelli F: Relationships between plasma insulin- like growth factor- I and insulin- like growth factor binding protein-3 and second breast cancer risk in a prevention trial of ... distribution of insulin- like growth factor- 1 receptor in human carcinomas Hum Pathol 2003, 34(8):803-8 Kanter-Lewensohn L, Dricu A, Girnita L, Wejde J, Larsson O: Expression of insulin- like growth factor- 1...

Ngày tải lên: 18/06/2014, 15:20

... modulation of insulin signaling and lifespan Proc Natl Acad Sci USA 2008, 105:63686373 14 Yamanaka Y, Wilson EM, Rosenfeld RG, Oh Y: Inhibition of insulin receptor activation by insulin- like growth factor ... Hwa V, Oh Y, Rosenfeld RG: The insulin- like growth factorbinding protein (IGFBP) superfamily Endocr Rev 1999, 20:761-787 Journal of Biology 2008, 7:18 18.4 Journal of Biology 2008, Volume 7, Article ... evolutionarily conserved function of the Drosophila insulin receptor and insulin- like peptides in growth control Curr Biol 2001, 11:213-221 Mohan S, Baylink DJ: IGF -binding proteins are multifunctional...

Ngày tải lên: 06/08/2014, 18:21

... (1995) Insulin- like growth factors and their binding proteins: biological actions Endocr Rev 16, 3–34 Firth SM & Baxter RC (2002) Cellular actions of the insulin growth factor binding proteins ... elevation of insulin- like growth factor (IGF) binding protein-1 decreases plasma free IGF-I and muscle protein synthesis Endocrinology 144, 3922–3933 Westwood M (1999) Role of insulin- like growth factor ... Huber R & Holak TA (2006) Structural basis for the inhibition of insulin- like growth factors by insulin- like growth factorbinding proteins Proc Natl Acad Sci USA 103, 13028– 13033 Westwood M,...

Ngày tải lên: 07/03/2014, 00:20

... R.E & Cascieri, M.A (1990) The roles of tyrosines 24, 31, and 60 in the high anity binding of insulin- like growth factor- I to the type insulin- like growth factor receptor J Biol Chem 265, 15648± ... Cascieri, M.A (1988) Structural analogs of human insulinlike growth factor I with reduced anity for serum binding proteins and the type insulin- like growth factor receptor J Biol Chem 263, 6233±6239 ... Hayes, N.S., Green, B.G & Bayne, M.L (1988) Mutants of human insulin- like growth factor I with reduced anity for the type insulin- like growth factor receptor Biochemistry 27, 3229±3233 14 Bayne,...

Ngày tải lên: 08/03/2014, 22:20

... cultured factor (IGF)-1 to IGF -binding proteins (IGFBPs), in insulin- like of NBI-31772, a small-molecule inhibitor of the binding of priActivitygrowth rabbit chondrocytes lin -like growth factor ... inhibit the binding of insulin- like growth factor (IGF) to IGF -binding proteins Bioorg Med Chem Lett 2003, 13:1931-1934 50 Roelfsema V, Lane MH, Clark RG: Insulin- like growth factor binding protein ... hormonal regulation of insulin- like growth factor binding proteins in bovine chondrocytes Endocrinology 1993, 133:563-570 Bunn RC, Fowlkes JL: Insulin- like growth factor binding proteolysis Trends...

Ngày tải lên: 09/08/2014, 01:23

... trình chạy điện di thể bảng 37 Đa dạng di truyền gen Insulin- like growth factor binding protein gà đa dạng di truyền gen Insulin- like growth factor binding protein gà Bảng Các cặp primer sử dụng nghiên ... AA quần thể nghiên cứu 39 Đa dạng di truyền gen Insulin- like growth factor binding protein gà đa dạng di truyền gen Insulin- like growth factor binding protein gà Bảng Tần số kiểu gen alen điểm ... Wang, Y.X Wang (2006) Identification of a single nucleotide polymorphism of the insulin- like growth factor binding protein gene and its association with growth and body composition traits in...

Ngày tải lên: 24/03/2014, 23:21

... imatinib resistance [55] Glycemic derangements related to insulin- like growth factors such as the pro-IGF-IIE and insulin- like growth factor- binding proteins have been described in GISTs, and they may ... Hankinson SE: Insulin- like growth factors and neoplasia Nat Rev Cancer 2004, 4:505-18 20 21 Tao Y, Pinzi V, Bourhis J, Deutsch E: Mechanisms of diseases: signalling of the insulin- like Growth Factor ... http://www.translational-medicine.com/content/8/1/117 Page of growth factors and insulin- like growth factor- binding proteins in relation to disease status and incidence of hypoglycaemia in patients with a gastrointestinal...

Ngày tải lên: 18/06/2014, 16:20

... index of body growth for lingcod Ophiodon elongatus using plasma insulin- like growth factor (IGF1) with the ultimate goal of measuring spatial differences in relative growth rates Insulin- like growth ... measure growth One of the principal hormones regulating growth is insulin- like growth factor (IGF1) In the laboratory, positive relationships between the concentration of plasma IGF1 and growth ... Larsen, S Moriyama, B Lee-Pawlak, and W W Dickhoff 1998 Insulin- like growth factor- I and environmental modulation of growth during smoltification of spring Chinook salmon Oncorhynchus tshawytscha...

Ngày tải lên: 04/09/2015, 17:15

... Efstratiadis A (1993) Role of insulin- like growth factors in embryonic and postnatal growth Cell 75, 73–82 26 Holt RIG (2002) Fetal programming of the growth hormone insulin- like growth factor axis Trends ... Zapf J (1985) Insulin- like growth factors and insuln: comparative aspects Diabetologia 28, 485–493 Clemmons DR (1989) Structural and functional analysis of insulin- like growth factors Br Med ... Silkmoth IGF -like peptide N Okamoto et al Members of the insulin- like peptide (ILP) family are present in a wide variety of metazoans In vertebrates, insulin and insulin- like growth factors (IGFs)...

Ngày tải lên: 18/02/2014, 13:20

... cell growth [2] The most well defined signaling mechanism regulating mTOR activity in skeletal muscle is the insulin like growth factor- 1 (IGF-1) ⁄ insulin- dependent pathway [5,6] Stimulation of ... Although it is clear that growth factorinduced activation of Akt blocks TSC1 ⁄ TSC2 inhibition of mTOR signaling [9–11], the molecular mechanism by which Akt inhibits the function of TSC1 ⁄ TSC2 protein ... concentration of wortmannin (10 lm) was required to inhibit insulin- induced activation of mTOR signaling in C2C12 myotubes (Fig S1A) so we cannot rule out the possibility of the inhibition of other...

Ngày tải lên: 15/03/2014, 11:20

... subcellular localization of the neurotrophin protein Neuropsychopharmacology 2007, 32:23512359 Bourguignon J, Gerard A: Role of insulin- like growth factor binding proteins in limitation of IGFI degradation ... of depressive -like behavior Psychoneuroendocrinology 2007, 32:516-531 Park SE, Dantzer R, Kelley KW, McCusker RH: Central administration of insulin- like growth factor- I decreases depressive -like ... Rosenzweig-Lipson S: Increasing the levels of insulin- like growth factor- I by an IGF binding protein inhibitor produces anxiolytic and antidepressant -like effects Neuropsychopharmacology 2007,...

Ngày tải lên: 19/06/2014, 22:20

... press 28 Heemskerk VH, Daemen MA, Buurman WA: Insulin- like growth factor- 1 (IGF-1) and growth hormone (GH) in immunity and inflammation Cytokine Growth Factor Rev 1999, 10:5-14 29 Jansson JO, Eden ... means ± standard error of the mean Numbers of patients for whom data were available are shown in parentheses ESR = erythrocyte sedimentation rate; IGF-1 = insulinlike growth factor 1; IL-1Ra = IL-1-receptor ... sedimentation rate; IGF-1 = insulin- like growth factor 1; IL-1Ra = IL-1-receptor antagonist; sIL-6R = soluble IL-6 receptor; TNF-α = tumor necrosis factor α TNF-α, a mediator of inflammation and joint...

Ngày tải lên: 09/08/2014, 01:21

... http://www.jnanobiotechnology.com/content/9/1/36 Page of 14 Kim JH, Cho YH, Park YL, Sohn JH, Kim HS: Prognostic significance of insulin growth factor- I receptor and insulin growth factor binding protein-3 expression ... and prognostic role of the insulin growth factor pathway members insulin- like growth factor- II and insulin- like growth factor binding protein-3 in serous effusions Hum Pathol 2009, 40:527-37 ... R: Plasma insulin- like growth factor- I and serum IGF -binding protein can be associated with the progression of breast cancer, and predict the risk of recurrence and the probability of survival...

Ngày tải lên: 11/08/2014, 00:23

... method offers the advantage of avoiding wt adenovirus infection and of yielding rAAV preparations that are presumed to be free of adenovirus http://www.virologyj.com/content/6/1/3 Insulin- like growth ... virus VP1 capsid protein J Virol 1988, 62:3356-3363 Jones JI, Clemmons DR: Insulin- like growth factors and their binding proteins: biological actions Endocr Rev 1995, 16:3-34 Gao G, Qu G, Burnham ... cells at a density of × 104 per well were plated in ml of growth medium in 24-well tissue culture plates just one day before transduction After incubation overnight, 0.5 ml of the growth medium was...

Ngày tải lên: 12/08/2014, 04:21

... regard, the effect of sepsis and the influence of nutrition on tissue protein metabolism and on the functioning of the growth hormone (GH) insulin- like growth factor- I (IGF-I) axis is of particular ... activation are implicated Circulating levels of IGF-I and of the insulin- like growth factor binding protein-I (IGFBP-I) are exquisitely sensitive to provision of nutrients, the former being increased ... induction of SOCS and both the presence of sepsis and the administration of PN [14] Administration of 16 hours of PN was associated with induction of the expression of hepatic mRNA of the SOCS...

Ngày tải lên: 13/08/2014, 08:20

... Activities of vascular endothelial growth factor (VEGF) family members PlGF, placenta growth factor; T.F svVEGF, Trimeresurus flavoviridis, snake-venom vascular endothelial growth factor Ligands Binding ... region of the brain called the ‘penumbra’ [14] Therefore, degree of angiogenesis appears to correlate with rate of recovery from stroke A variety of angiogenic factors such as VEGF, fibroblast growth ... safety of VEGF-E appears greater than that of VEGF-A Therapeutic aspects of VEGF in brain diseases hypoxia-inducible factor (HIF) system [17] Further study is needed to clarify which factor is...

Ngày tải lên: 18/02/2014, 11:20

... of insulin- like growth factor I Mol Cell Biol 19, 3115– 3124 James PL, Stewart CE & Rotwein P (1996) Insulin- like growth factor binding protein-5 modulates muscle differentiation through an insulin- like ... (1996) Growth hormone and the insulin- like growth factor system in myogenesis Endocrine Rev 17, 481–517 DeVol DL, Rotwein P, Sadow JL, Novakofski J & Bechtel PJ (1990) Activation of insulin- like growth ... (1993) A Role of insulin- like growth factors in embryonic and postnatal growth Cell 75, 73–82 Louvi A, Accili D & Efstratiadis A (1997) A growthpromoting interaction of IGF-II with the insulin receptor...

Ngày tải lên: 19/02/2014, 06:20

... day of life Eur J Pediatr 145: 187-189 Juul A, Bang P, Hertel NT et al (1994) Serum insulin- like growth factor- I in 1030 healthly children aldolescent, and adults: relation to age, sex, stage of ... Continuous administration of growth hormone (GH) does not prevent the decrease of IGF-I gene expressionin zinc-deprived rats despite normalization of liver GH binding Growth Horm & IGF Res 8: ... Thissen JP, Collette et al 1996 Zinc supplementation increases growth and circulating insulin- like growth factor I (IGF-I) in Vietnamese growth- retarded children Am J Clin Nutr 63: 514-519 Ninh NX,...

Ngày tải lên: 25/03/2014, 03:22

... Torres-Aleman I: Role of serum insulinlike growth factor I in mammalian brain aging Growth Horm IGF Res 2004, 14(Suppl A):S39-43 30 Tong M, Dong M, de la Monte SM: Brain insulin- like growth factor and neurotrophin ... Department of Physiology, School of Medicine, University of Málaga, 29071 Málaga, Spain 2Department of Medical Physiology, CEU-San Pablo University School of Medicine Institute of Applied Molecular ... translocase; AUF: arbitrary units of fluorescence; bw: body weight; EC: Enzyme Commission of the International Union of Biochemistry; IGF: Insulin- Like Growth Factor; MDA: malondialdehyde; MMP:...

Ngày tải lên: 18/06/2014, 22:20