transcription factor protocols

... pH 7.7. Transcription Factor Protocols Edited by Martin J. Tymms Methods in Molecular Biology Methods in Molecular Biology TM TM VOLUME 130 HUMANA PRESS HUMANA PRESS Transcription Factor Protocols Edited ... tran- scription factors or developmental regulators. Other DH sites can represent specific structural features, such as centromeres. 29 From: Methods in Molecular Biology, vol...

Ngày tải lên: 11/04/2014, 07:03

... the ethyl- ene response factor ⁄ Apetala2 transcription factor family, and that this is mediated by their meprin and TRAF (tumor necrosis factor receptor-asso- ciated factor) homology (MATH) ... and Ox40 are members of a tumor necrosis factor (TNF)-nerve growth factor receptor subfamily that bind TNF receptor-associated factors and activate nuclear factor kappaB. Mol Cell Biol...

Ngày tải lên: 18/02/2014, 06:20

... AP-2 transcription factor: AP-2 beta. Development 121, 2779– 2788. 6 Oulad-Abdelghani M, Bouillet P, Chazaud C, Dolle P & Chambon P (1996) AP-2.2: a novel AP-2-related transcription factor ... AP-2 family transcription factors. J Biol Chem 275, 29701–29708. 11 Williams T & Tjian R (1991) Analysis of the DNA-binding and activation properties of the human transcription facto...

Ngày tải lên: 18/02/2014, 08:20

... [11], exist for investigating transcription factors and transcriptional regulation, but the main purpose of using these methods is not in quantifying transcription factor DNA binding. Our goal ... intensively studied transcription factors is heat shock factor 1 (HSF1). HSF1 binding to its response elements in target gene promoters is an established model system of inductive transcrip...

Ngày tải lên: 18/02/2014, 14:20

... surfactant protein B gene promoter is a target for thyroid transcription factor 1 and hepatocyte nuclear factor 3, indicating common factors for organ- specific gene expression along the foregut ... should still emerge under physiological conditions, when the HD is part of a much larger transcription factor, and determine the extent of the conformational changes and, hence, the energe...

Ngày tải lên: 18/02/2014, 16:20

... other transcription factors. We chose E2F [29,30], ETS1 [31,32], hypoxia-inducible factor 1 (HIF-1) [33], hepatocyte nuclear factor 4 (HNF4), and c-Myc [34], and collected seed groups for these factors ... method relies on the assumption that the transcription factor of interest shows some biological activity in the data. If, for example, the transcription factor of interest is...

Ngày tải lên: 18/02/2014, 18:20

... http//http://www.uni-frankfurt.de/fb15/ mikro/euroscarf/), we tested all viable transcription factor deletion strains for their ability to grow in the presence of sorbic acid. This approach identified the transcription factor essential for Pdr12p ... C-terminal acti- vation domain, which is necessary for transcriptional activation of the target genes by other Zn(II) 2 Cys 6 transcript...

Ngày tải lên: 19/02/2014, 00:20

... studies indicate that growth factors such as nerve growth factor, insulin-like growth factor, fibroblast growth factor, epidermal growth factor (EGF), and hepatocyte growth factor can suppress apoptosis ... forkhead transcription factor FKHR [25], a proapoptotic tran- scription factor, thereby inhibiting them, the PtdIns3- K ⁄ Akt signaling pathway has emerged as the major mechani...

Ngày tải lên: 19/02/2014, 06:20

... Description and functionality of transcriptions factor hubs. Transcription factor (TF), degree (k), betweenness centrality (b). TF Description Associate disease kb· 10 3 TBP Basal transcription machinery ... them. Abbreviations ER, Erdo ¨ s-Re ´ nyi; HTFN, human transcription factor network; SF, scale free; SW, small world; TF, transcription factor. FEBS Journal 272 (2005) 642...

Ngày tải lên: 19/02/2014, 07:20

... (bhlhb2) and DEC2 (bhlhb3) are basic helix-loop- helix (bHLH) transcription factors which bind to CAC- GTG E-boxes and suppress transcription from target genes [7–12]. Expression of DEC1 and ... activities of the o ther group B bHLH proteins. In addition to BMAL1, DEC1 can bind to various transcription factors such as USF2 [29], MASH1 [23] and E47 [31], or t o co-repressors such as H DA...

Ngày tải lên: 19/02/2014, 16:20