... among ACS patients is very likely to contribute towards enhanced pro-inflammatory status in cardiovascular patients and development of secondary complications of atherosclerosis Conflict of Interest ... conducted to unsure specificity of the primers and probe Real-time PCR was performed with the iCycler IQ ystem (Biorad, USA) µl of extracted DNA was analyzed with the PCR mixture in a total volume of ... presence of 16S rRNA by conventional PCR, we have found that patientswith ACS were positive for the genetic marker of C pneumoniae Finally, just patients (out of 18) had increased levels of two...
... reported previously to correlate with the onset of ARDS or SIRS and subsequent survival ARDS and SIRS seriously affect the prognosis of postoperative patients Anastomotic Page of 11 leak and pneumonia ... indicators of clinical course are shown (Additional File 1) With respect to gene markers’ association with surgical parameters, upregulation of TNF-a mRNA correlated with increased duration of anesthesia ... indicator of poor prognosis (as are days of ventilator dependence, days of ICU stay, and days of SIRS (p < 0.0001); a high level at POD3 predicted the onset of pneumonia (p = 0.021) Days of ventilator...
... foot could be due both to the presence of excessive adipose tissue inside the thighs, as previously suggested [5] and to the presence of flat foot dueto the overload Recent studies of the load ... respect to obese patients and healthy subjects, and is likely to be the landmark of the pathological gait strategy of PWS patients In relation to knee joint, the 63.16% (12/19) of PWS patients presents ... daily activity such as walking Taken into consideration the peculiar clinical picture ofpatientswith PWS, aim of our study was to characterize the gait pattern of these subjects by using 3D-Gait...
... did not tolerate ketoprofen on single-blind, placebo-controlled oral challenges.52 On subsequent challenges, of (37%) ketoprofen reactors did not tolerate nimesulide Three ketoprofen reactors reported ... urticaria than patientswith a history of single intolerance to NSAIDs other than aspirin.45 Patients already presenting with a history of multipleNSAID intolerance, with or without underlying chronic ... remain the only way to assess tolerance or intolerance to specific NSAIDs in subjects with a history of urticaria induced by these substances and, hence, to respond satisfactorily topatients requests...
... complete relief of symptoms and return to full functioning in all areas of life) within weeks of therapy [5] A better understanding of the factors that influence the outcome of a depressive episode ... and social factors, and the presence of other medical diseases, were found to be associated with a negative outcome of a depressive episode and hence with a reduced possibility of achieving remission ... mood symptoms may not provide a full understanding of factors influencing outcomes of depression Therefore, the use of appropriate instruments for the assessment of health-related quality of life...
... performed on a total of 404 patients having a total of 797 post-baseline observations (see Table 5) Baseline MCS value was associated with MCS score through the study with on average scores of MCS 0.35 ... confirmed by Trompenaars et al [5], who showed lower levels of quality of life among patientswith major depression with respect to those with dysthymia and adjustment disorders A large population-based ... symptoms, including pain, are a specific component of depression, and were studied as a factor influencing the quality of life ofpatients In a recent Spanish study involving 1,150 primary care patients...
... immunoglobulin (IVIG) has emerged as a powerful tool to improve patient status or to cure the disease In most instances, immunosuppressed patients or patientswith haematopoietic disorders have been treated ... mechanisms have been proposed to explain the immunomodulatory effects of IVIG These include modulation of cytokine production and the neutralization of circulating autoantibodies [11] In addition, ... associated with an enhanced formation of immunoglobulin complexes, resulting in the induction of complement and cytokines and in the stimulation of inflammatory reactions In addition, at the end of the...
... amplified in ST samples from three of the seven patientswith RA (43%) and from three of the six with OA (50%) Accordingly, the proportion of ST samples from ReA and UA patients yielding positive PCR ... our patients may be dueto the use of the primer pair (Bac08F/Uni1390R) as well as the use of the T4 Gene 32 Protein, which may increase the yield of PCR products [3032] Sequence analysis of the ... understanding of the contribution made by intestinal microflora to human biology is needed to elucidate the potential role played by microflora in the pathogenesis of ReA [41-44] Our approach of cloning...
... re-induction with CAG Efficacy of CAG regimen for newly diagnosed vs relapsed /refractory AML There were a total of 327 new AML patients from 14 studies, and 370 patientswith relapsed /refractory (R/R) ... studies involving 397 patients, of whom 144 (36.2%) were induced twice with CAG Of the patients who received one cycle, 46.60% (185/397) went into CR, another 8.31% (33/397) of the patients achieved ... CR rate of CAG was significantly higher than those of other regimens, with an odds ratio of 2.43 (95% CI, 1.52-3.88) (Figure 5) Cardiotoxicity and early death rate of CAG The toxicity of CAG in...
... Characteristics of the patients Characteristics of the patients at the time of diagnosis are listed in Table The median age of these patients was 70 (60–84) years Seven patients had history of myelodysplastic ... regimen with less toxicity in elderly patientswith AML Furthermore, of the patientswith AML secondary to MDS achieved CR, suggesting HA regimen is also effective in elderly patientswith AML ... chemotherapy of homoharringtonine Probability of overall survival in elderly patientswith AML Probability of overall survival in elderly patientswith AML undergoing induction chemotherapy of homoharringtonine...
... two Japanese patientswith Paget's disease of the bone To the best of our knowledge, this is the first report of a long-term follow-up ofpatientswith PDB after a six-month treatment with low-dose ... Japanese patientswith PBD In Case 2, we had to resume her treatment twice to maintain normal levels of T-ALP and uNTX, and the relief of bone pain These results suggested that the effects of low-dose ... treat Japanese patientswith PBD since July 2008 It might be better to treat patients like Case with a high dose of oral risedronate (17.5 mg per day) for eight weeks in accordance with the guidelines...
... varying from two to twelve patients, of which to were CNCM patients A total of 231 CNCM and 612 NN patients were in the final dataset In the CNCM region, 67.7% was diagnosed with severe mental ... needs more often may come to light In addition, a small group ofpatientswith common, less severe mental disorders, outside the range of SMI or MMI, were not excluded to avoid a loss of power ... network, with higher likelihood of return to preonset employment These first episode patients, particularly those with psychotic disorders, often have low insight and therefore are less likely to formulate...
... a method of Le Fort I osteotomy in combination with simultanously bone grafting in the anterior and posterior maxilla and placement of endosseous implants for treatment ofpatientswith atrophied ... with Grafton®-DBM-Putty (Osteotech, Eatontown, NJ, USA) To fulfill the patient's desire the teeth 11 and 21 were left in the maxilla Case report The patient was a 46-year-old man, afflicted with ... Medicine 2007, 3:2 The surgial approach of maxillary advancement is especially challenging in cleft patientsdueto the impared bony situation This report describes a methodological approach of treating...
... of evidence [26] From this perspective, and in order to assess the face validity of the tool, a sample of eight psychiatrists with expertise in treating schizophrenic patientswith symptoms of ... items in all patientsof the sample and to explore the unidimensionality of the PANSSEC The equamax rotation was chosen to be consistent with many previous studies of the PANSS The factor’s extraction ... reduction of 58% on PANSS-EC; ratings of much improved corresponded to median reduction of 38% on PANSS-EC; and ratings of minimally improved corresponded to median reduction of 18% on PANSS-EC Montoya...
... more patients need to be included for further study, one certain clue, which can be provided to clinical doctors, is that some patientswith HBeAg-positive CHB could probably be expected to achieve ... cases during the total course of anti-viral therapy Discussion The aims of treatment for CHB are to achieve sustained suppression of HBV replication, thereby inducing remission of liver diseases ... shortest period of treatment was 20 weeks) or sequential therapy with pegasys and baraclude (the longest period of treatment with pegasys was 24 weeks, the shortest period of treatment with pegasys...
... large, state of the art, adult intense care unit to use HFOV There is no data to indicate that the survival of adult patientswith ARDS is improved with the use of HFOV Animal data Most of the studies ... had been ventilated with CMV for fewer days before institution of HFOV compared with non-survivors, suggesting potential benefit to early use of HFOV in the support ofpatientswith ARDS Two additional ... adults with ARDS The early use of HFOV, perhaps by mitigating ventilator-induced lung injury, may be advantageous Con: No, HFOV is not useful in the management of adult patientswith respiratory...
... inflammatory cascade associated with CPB [7,9] Tumor necrosis factor-α (TNF-α), interleukin (IL)-6 and IL-8 (proinflammatory cytokines) may contribute to myocardial dysfunction and increased apoptosis ... observed in any of the patients However, 65% of the POEE patients fulfilled at least one MOD criterion as defined by Trotter et al [23] Postpericardiotomy syndrome with effusions and fever of non-infectious ... modulators of the inflammatory response TNF-α stimulates human vascular endothelium, thus mediating leukocyte recruitment to sites of inflammation IL-10 release is specific to CPB surgery [7] and patients...
... bleeding risk for all patientswith severe sepsis In these trials, patients at increased risk for bleeding (e.g some patientswith multiple trauma) or patientswith severe thrombocytopenia (i.e platelet ... (activated) topatientswith platelet counts of 30,000/mm3 or less Indeed, serious bleeding events in drotrecogin alfa (activated) patients appear to be associated with severe thrombocytopenia, ... those with scores below 25 amounted to 9/436 (2.1%) In PROWESS (F1K-MC-EVAD), 75% (634/850) ofpatients who received drotrecogin alfa (activated) and a similar percentage (76%; 637/840) of patients...
... status ofpatientswith COPD? IPV is a mucus clearance device Inflammatory cells are abundant in the sputum ofpatientswith chronic mucus retention These cells are able to release mediators that ... studies are needed to determine the long term effects of IPV and to clarify the impact of IPV in the management ofpatientswith acute exacerbations of COPD Key messages • IPV led to a significant ... incidence of NIV use and a shorter duration of hospital stay In acute exacerbations of COPD patients, NIV has profoundly changed the management and outcome of these patients [2] The results of several...