... amplifiedusing the primer pairs listed in Table 1, and then sequenced to determine the orientation ofthe fragments in the repor-ter vector. These constructs were then transfected into P19cells ... of miR9 To detect the transcript level of pri-miR9, the upstreamregion of pri-miR9-1 was isolated from the genomic DNA of HeLa cells and cloned into a promoterless vector,pGL3_Basic vector (Promega, ... transcriptionfactors that are required to maintain the neuronaldifferentiation of stem cells.Moreover, the molecular mechanisms ofthe bioge-neses of a number of miRs are equivocal. miR23a, which was...
... 3Â5Â-guanosine), to facilitate dockingintotheactivesiteofRTA.Here, twoofthe models proposed [10] have beenexamined (Fig. 1). The third model in whichthe hexanucle-otide is bound tothe active site of ... red. C1 of the hexanucleotide is at the bottom left and the target adenine is at the top of each model. The sidechains of RTA are shown in blue. (A) Model 1 has the tetraloop bound in the active ... determine whether the reduction inactivity of this RTA variant could be attributed solely to the change in charge and size ofthe sidechain of this singleresidue. The structure of RTA R213D is essentially...
... half ofthe year, down from net inflows of EUR 142 billion for the same period in 2010. This reduction reflects the change in investor confidence from a high level at the beginning of 2010 to ... Italy for whichthe funds of funds data areincluded in the other fund categories; (3) net sales of non-UCITS are included in "other" funds, except net sales of special funds, which are ... into UCITS amounted to EUR 48 billion during the first half of 2011, slightly behind the EUR 55 billion recorded in the first half of 2010. Long-term UCITS attracted EUR 87 billion during the...
... percent during the quarter. Over the first half of 2012, total net assets of UCITS have increased by 5.6 percent. The number of UCITS at end June 2012 stood at 35,766, compared to 36,106 at ... Italy for whichthe funds of funds data areincluded in the other fund categories; (3) net sales of non-UCITS are included in "other" funds, except net sales of special funds, which are ... debt crisis increased investor caution during the second quarter. This can be seen from the trends in monthly net sales1 for UCITS. Equity funds continued to suffer on account ofthe poor...
... between the projection ofthe tilt ofthe z axis on the xÂ,y plane (dened direction of tilt of z and the x axis), and j % a + c denes the location ofthe rhombic (x, y) axes. The orientation ofthe ... a distal Tyr at position E7 as the source ofthe H-bond to ligand on the basis of apartial sequence, which had indicated a Tyr on the distalE-helix. The similarity in the 1HNMRspectraofthethree ... data of Pe HbO2. The static structure of neither WT nor rWT metMb would allow the TyrE7 ringreorientation without significant distortion ofthe hemepocket.Comparison to other nematode/trematode...
... that the effect of APMA on ACE sheddingwas not as a result of over-expression ofthe protein.Together these data confirm that APMA induces the shedding of ACE but not the shedding of APP from two different ... failed to activate the shedding of APP, revealing that this is the first pharmacological agent to clearly differentiate between the shedding of APP and ACE. What is emerging fromthis and other ... neither ADAM10 nor TACE are involved in the shedding of ACE and that APMA, which activates adistinct ACE secretase, isthe first pharmacological agent to distinguish between the shedding of ACE...
... sphere is equal to a circle whose radius is equal tothe line drawn from the vertex of the segment tothe circumference ofthe circle whichisthe base of the segment.5Next to these, that, in ... polygon is smaller than the circumference ofthe circle; for each ofthe sides ofthe polygon is smaller than the circumference ofthe circle whichis cut by it.textual commentsIt is customary ... grateful tothe Curator of Manuscripts there,William Noel, tothe conservator of manuscripts, Abigail Quandt, to the imagers ofthe manuscript, especially Bill Christens-Barry, RogerEaston, and...
... Spanish Auto in English original poetry. The nearest approach to it, and the only one, is The Prometheus Unbound of Shelley. There, indeed, The Earth, Ocean, The Spirits ofthe Hours, The ... eloquent verses in praise of these saints, and set them on their tombe. There is mention of them also in the Romaine Martirologe, and in that of Usuardus: as also in the 5. tome of Surius; in Cardinal ... venture to call the region of sacred mythology, as in The Sibyl of the East, in whichthe profound legends identifying the Cross of Calvary and the Tree of Life are wrought up into a poem of surpassing...
... augments, the transformation of photon densities is inverse (see in Fig 1b). This reveals that the increase of one mode photon density caused in the decrease ofthe other one. Fig. 1a. Gain ... influence of field coupling coefficients 12θand21θon the photon densities is inverse (see Fig 3a, 3b). This shows that in the process of interation between the fields oftwo modes, the increase ... Journal of Science, Mathematics - Physics 23 (2007) 139-142 1413.2.Losscoefficientsiβ In this case, the augmentation of loss coefficient of one mode will decrease the photon density of this...
... sorrowful. Then when Juliet shot herself in the head, it was really dramatic, as you heard the sound of the shot. To summarise thetwo films, all I can say is that I loved them both, because they are ... because they are so different,but if I had to choose, I’d choose the Luhrmann version, starring Claire Danes and LeonardoDiCaprio, just because I loved the ending. ...