what kind of weather is associated with cirrostratus clouds
Báo cáo sinh học: "Membranous expression of Her3 is associated with a decreased survival in head and neck squamous cell carcinoma" pot
... primary HNSCC tissues, 20 matching metastatic tissues and 17 recurrent HNSCC tissues The clinical information of these patients was obtained from the University of Immunohistochemistry and scoring ... clear[27,30,36] In case of breast cancer, membranous staining is the criterion for positivity[17] Another interesting finding is that Her2 expression was associated with histological grade, with the most ... Special thanks to Ms Angela Miller of the Biorepository and Tissue Research Facility of The University of Virginia for construction of the TMAs used in this study This research was supported by the...
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báo cáo hóa học:" Membranous expression of Her3 is associated with a decreased survival in head and neck squamous cell carcinoma" doc
... primary HNSCC tissues, 20 matching metastatic tissues and 17 recurrent HNSCC tissues The clinical information of these patients was obtained from the University of Immunohistochemistry and scoring ... clear[27,30,36] In case of breast cancer, membranous staining is the criterion for positivity[17] Another interesting finding is that Her2 expression was associated with histological grade, with the most ... Special thanks to Ms Angela Miller of the Biorepository and Tissue Research Facility of The University of Virginia for construction of the TMAs used in this study This research was supported by the...
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báo cáo khoa học: "Down-regulation of TM4SF is associated with the metastatic potential of gastric carcinoma TM4SF members in gastric carcinoma" ppt
... protein levels were inversely associated with lymph node metastasis of gastric carcinoma Furthermore, the reduction of CD9 protein was associated with distant metastasis of gastric cancer Our results ... decreased levels of CD9 are strongly associated with an increased risk of recurrence, especially in patients with N0 nodal status and M0 metastatic status These findings are consistent with previous ... levels of CD63 were associated with distant metastasis and CD63 protein correlated lymph node status Taken together, these results suggested that decreased levels of CD63 were associated with a...
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Báo cáo y học: "Relaxin''''s induction of metalloproteinases is associated with the loss of collagen and glycosaminoglycans in synovial joint" ppsx
... fibrocartilaginous disc explants Our findings are consistent with the hypothesis that relaxin-mediated induction of MMPs is associated with the loss of matrix macromolecules that could compromise tissue function ... this is the first study to demonstrate a similar targeting of fibrocartilaginous tissues from the synovial TMJ, and may implicate this hormone in the pathogenesis of TMJ disease in a subset of ... values of the control hemisection within each animal and the fold changes were plotted as histograms The statistical significance of differences was determined by single-factorial analysis of variance...
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Báo cáo y học: "High nuclear expression of STAT3 is associated with unfavorable prognosis in diffuse large B-cell lymphoma" doc
... immunoreactivity Statistics The Chi-square test was used to analyze the consistence of expressions of STAT3 in nucleus and P-STAT3 Correlation analysis of the STAT3 expression and the PSTAT3 level with clinicopathological ... thank Professor Wei Song in Central Laboratory of Beijing Cancer Hospital for her kind help in the final revision Page of 6 10 Author details Department of Lymphoma, Peking University School of Oncology, ... doi:10.1186/1756-8722-4-31 Cite this article as: ZL et al.: High nuclear expression of STAT3 is associated with unfavorable prognosis in diffuse large B-cell lymphoma Journal of Hematology & Oncology...
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Báo cáo y học: " Risk of malnutrition is associated with mental health symptoms in community living elderly men and women: The Tromsø Study" pdf
... category of BMI 25-27.4 kg/m2 Discussion In this study, we found that mental health symptoms were strongly associated with the risk of malnutrition in elderly individuals Both the risk of malnutrition ... level of education, and a smaller proportion had a history of smoking Mean BMI was 27.0 kg/m2 in both genders Risk of malnutrition (combining medium and high risk) was found in 7.1% (222/3112) of ... SCL-10 the assessment of the relationship between risk of malnutrition and mental health Increased risk of malnutrition (combining medium and high risk) was found in 7.1% of the individuals in...
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Báo cáo y học: " Activated mammalian target of rapamycin is associated with T regulatory cell insufficiency in nasal polyps" pps
... results show that rapamycin administration is associated with elevated Foxp3+ Tregs in cultured nasal polyps Inhibition of mTOR signaling by rapamycin is associated with enhanced Foxp3 expression ... Infiltration of pmTOR+ cells and Foxp3+CD4+ cell in nasal tissues by histologic examination Infiltration of pmTOR+ cells and Foxp3+CD4+ cell in nasal tissues by histologic examination The number of pmTOR+ ... polyps is of significant interest In the present study, we investigated the phosphorylation status of mTOR in a group of Chinese CRSwNP patients by immunohistochemistry, and the infiltration of Foxp3+CD4+...
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Báo cáo y học: "Intensivists'''' base specialty of training is associated with variations in mortality and practice patterns" docx
... System (TISS) over first 24 hours of admission to ICU, year of admission, time of year of admission (by 28-day block to coincide with trainees' length of rotation), level of care at time of admission ... file is available with the online version of this paper; it contains a total of 12 tables providing more detailed results of the analyses Tables S1 and S2 list the variables associated with ICU ... DNR) and discharge, admission diagnosis, Intensivist gender, Intensivist base specialty of training, years since completion of Critical Care Medicine Fellowship, and ICU occupancy at admission and...
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Báo cáo y học: " A Novel Variable Number of Tandem Repeat of the Natriuretic Peptide Precursor B gene’s 5’-Flanking Region is Associated with Essential Hypertension among Japanese Females"
... models with a deletion of this gene develop disorders that resemble the symptoms of subjects with a deleted allele in the 5’-untranslated region of NPRA We previously isolated a missense mutation of ... 5’-flanking region of the NPPB gene was discovered This polymorphism was associated with EH in female subjects However, this finding does not necessarily imply that there is a relationship between ... (GenBank accession number AB265677) This VNTR polymorphism is a tandem repeat of the 4-nucleotide sequence TTTC (Fig 1A) There were alleles of this VNTR polymorphism, ranging from 9-repeat to 19-repeat...
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Tài liệu Báo cáo khoa học: The splicing factor ASF/SF2 is associated with TIA-1-related/ TIA-1-containing ribonucleoproteic complexes and contributes to post-transcriptional repression of gene expression doc
... control of gene expression As each step of the RNA metabolism is tightly regulated, the regulation of mRNA export, stability and translation rate is essential for the control of the expression of ... Tris, pH 8.0) in the presence of RNAse A (10 lgÆmg)1 extract) After 15 h of binding at °C, beads were washed twice with mL of IgG BB and once with mL of Tev cleavage buffer (Tev CB: 25 mm Tris, ... reflect the capacity of TIAR to be associated with polysomes Although the association of DDX21 with TIAR relies on RNA intermediate, DDX5, hnRNP M and ASF ⁄ SF2 are associated with TIAR by protein–...
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Tài liệu Báo cáo khoa học: Down-regulation of heme oxygenase-2 is associated with the increased expression of heme oxygenase-1 in human cell lines docx
... cultured human cells Discussion We have shown that the selective knockdown of HO-2 expression with each of two different siRNAs is consistently associated with increased expression of HO-1 mRNA and ... measurement of heme content is useful for evaluation of heme dynamics in cultured cells Role of heme metabolism in cellular heme content Regulatory role of free heme in expression of HO-1 To evaluate ... influence the expression of HO-1 The dominant expression of HO-2 protein, in comparison with the low expression of HO-1 protein, in H146 small cell lung cancer cells is of particular interest because...
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Báo cáo khoa học: Muramyl-dipeptide-induced mitochondrial proton leak in macrophages is associated with upregulation of uncoupling protein 2 and the production of reactive oxygen and reactive nitrogen species docx
... enhancement of non-specific resistance to viral and bacterial infections, potentiation of anti-tumour activity of macrophages, manipulation of cytokine release and restoration of haematopoiesis [18–20] ... that the activity of UCP2 is consistent with the level of free radicals Results In vitro effect of muramyl peptides and lipopolysaccharide on respiratory mitochondrial activity of murine peritoneal ... as MB, is capable of inducing mitochondrial proton leak in the spleen and liver of injected mice Moreover, it is of importance to note that the maximum in vivo effect of MDP and some of its derivatives...
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Báo cáo khoa học: Cellular refractoriness to the heat-stable enterotoxin peptide is associated with alterations in levels of the differentially glycosylated forms of guanylyl cyclase C pdf
... differentially glycosylated forms of GC-C It is possible that the reappearance of the 145 kDa form following removal of ST peptide was a consequence of further glycosylation of the ER -associated 130 kDa form, ... synthesis was not required, and a pool of ER -associated GC-C is available to replenish the ligand-activable form of the receptor, lost from the cell surface on ST addition The levels of cGMP ... inhibited the reacquisition of responsiveness by 50% This shows that modification of the a-1,6 arm of the mannose residues was essential to allow formation of the 145 kDa form of GC-C and ligand...
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Báo cáo khoa học: N-Methylation in polylegionaminic acid is associated with the phase-variable epitope of Legionella pneumophila serogroup 1 lipopolysaccharide pptx
... it to virulence For this purpose, the isogenic mutant 5215 was generated by deletion of the LPS biosynthesis operon ORF 8±12 in the virulent wild-type RC1 With the aid of this genetically de®ned ... careful NMR spectroscopic analysis was used to elucidate the structure of N-methylated derivatives of legionaminic acid Comparison of the 1H NMR spectra of the OPS of pool III from all three investigated ... nitrogen of an N-acetimidoyl group, i.e that an (N,N-dimethylacetimidoyl)amino group is present (Fig 8, structure 2) This group is linked to C5 of a legionaminic acid residue, which is substituted with...
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Báo cáo khoa học: Suppression of urokinase receptor expression by bikunin is associated with inhibition of upstream targets of extracellular signal-regulated kinase-dependent cascade pptx
... possibly through suppression of upstream targets of ERK Thus, one of the functions of bikunin is the regulation of uPA synthesis and uPA binding by modulating uPAR It is most likely that the PMA-induced ... reported that bikunin expression is associated with a less malignant phenotype [24] There is evidence that bikunin significantly prevented pulmonary metastasis of mouse Lewis lung carcinoma 3LL cells ... increased level of phosphorylated ERK is associated with increased level of cell-surface uPAR, which results in enhanced invasion [10] To determine the role of bikunin in the regulation of ERK1/2 phosphorylation,...
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Báo cáo khoa học: The unique pharmacology of the scorpion a-like toxin Lqh3 is associated with its flexible C-tail pdf
... isomerization of the P9-E10 peptide-bond was most likely unrelated to the pH dependence of Lqh3 To test the possibility that the pH-dependent binding of Lqh3 is associated with protonation of surface histidines ... 6B) Discussion Insight into the molecular basis of preferential interactions of scorpion a-toxins with insect or mammalian Navs was thus far obtained mainly from mutagenesis and comparison of bioactive ... populations (His66, His43; Fig 7C,D), such a conformational change may provide the basis for the dependence of Lqh3 binding on pH This hypothesis is supported by the decreased sensitivity to pH of the...
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Báo cáo khoa học: A distinct sequence in the adenine nucleotide translocase from Artemia franciscana embryos is associated with insensitivity to bongkrekate and atypical effects of adenine nucleotides on Ca2+ uptake and sequestration pdf
... alignment of the Artemia ANT protein sequence with that of other species (Xenopus, Drosophila, mouse isoforms 1, 2, and 4, rat isoforms and 2, bovine isoforms 1, 2, 3, and 4, and human isoforms ... compared with the known structure of bovine ANT Comparison of the predicted three-dimensional structure of Artemia ANT with that of bovine ANT The structure of bovine ANT (isoform 1) is known ... PTP As shown in Fig 2A, this was not observed in mitochondria isolated from embryos of A franciscana It is of note that, in the presence of oligomycin and ADP, addition of Ca2+ failed to induce...
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Báo cáo khoa học: Homologous desensitization of guanylyl cyclase A, the receptor for atrial natriuretic peptide, is associated with a complex phosphorylation pattern pot
... phosphorylation of this residue in the inhibitory regulation of GC-A activity To follow this hypothesis, we tested the influence of the substitution of Ser487 with glutamate on the process of homologous ... top) This suggests that this phosphorylation site, in contrast with the others, is phosphorylated during homologous desensitization Hence, homologous desensitization of GC-A is associated with ... accomplished using multiquant 1.0 software (Applied Biosystems) [33] Estimates of the relative abundance of phosphorylated tryptic peptides of GC-A isolated from HEK293 cells treated with ANP...
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Báo cáo khoa học: Mutation of epidermal growth factor receptor is associated with MIG6 expression docx
... [14,15] and its loss is associated with ErbB2 ⁄ HER-2 oncogenic potency leading to Herceptin resistance [16] Furthermore, its overexpression is associated with down-regulation of phosphorylated-ErbB2 ... transcriptional regulation of this mutant is of clinical importance in terms of contributing towards our understanding of patient sensitivity to Iressa, as well as side effects and drug resistance The results ... showed that MIG6 expression is correlated with the phosphorylated active state of EGFR and that ERRFI1 expression is associated with basal EGFR kinase activity in the absence of ligand Furthermore,...
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báo cáo hóa học:" Higher percentage of CD133+ cells is associated with poor prognosis in colon carcinoma patients with stage IIIB" pptx
... percentage of CD133+ tumor cells and the prognosis of colorectal cancer patients This study showed that the percentage of CD133+ tumor cells was associated with the prognosis among patients with locally ... Kojima's study, a total of 189 patients consisted of 106 cases of colon cancers and 83 cases of rectal cancers with TNM stages varying from I to VI, that is, one group of patients with a definite stage ... function of CD133 is unknown, preliminary evidence proposed that expression of CD133 is associated with the activation of stemness-related signal pathway, resistance to apoptosis and bioenergetic...
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