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use of splicing reporter minigene assay to evaluate the effect on splicing of unclassified genetic variants

Bóa cáo y học:

Bóa cáo y học: "Use of an integrated clinical trial database to evaluate the effect of timing of drotrecogin alfa (activated) treatment in severe sepsis" ppt

Báo cáo khoa học

... comparisons) to adjust for the non-randomized nature of the data The values of major interest in these models correspond to the interaction between treatment and time to treatment In addition to the ... care at the discretion of the investigator Inclusion criteria were very similar across trials and, in brief, consisted of the following: infection, presence of at least three criteria of the systemic ... (within 24 hours of OD) does not change the course of septic shock or respiratory failure in isolation but has a more pronounced effect on the resolution of ODs in the form of MOD This study...
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báo cáo hóa học:

báo cáo hóa học:" Use of a novel cell-based fusion reporter assay to explore the host range of human respiratory syncytial virus F protein" ppt

Hóa học - Dầu khí

... transcriptional transactivator fusion protein consisting of the GAL4 DNA-binding domain fused to the activation domain of NFκB These effector cells were mixed with a separate set of reporter cells that ... indicating fusion of the two cell populations The maximum signal observed from mixing the effector and reporter populations was similar to the signal obtained when the activator and reporter plasmids ... fusion with the host cell membrane is believed to be mediated by insertion of a hydrophobic fusion peptide into the host cytoplasmic membrane after binding of F protein to a target receptor on the...
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Agent-based and analytical modeling to evaluate the effectiveness of greenbelts potx

Agent-based and analytical modeling to evaluate the effectiveness of greenbelts potx

Thời trang - Làm đẹp

... deviations of either trial, than does the tent pattern (Table 2) This is because the location of the seed service center in the middle of the left edge coincides with the top of the ridge of the ... outcomes The outcomes of ABM 1D were evaluated by running the model until the total number of agents equals the total number of cells to the left of the greenbelt This is equivalent to the constraint ... constraint on the mathematical model that g!M (Section 2.1) We then recorded whether or not any of the agents located to the right of the greenbelt To measure the degree to which the greenbelt served to...
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báo cáo hóa học:

báo cáo hóa học: " An exploratory study to evaluate the utility of an adapted Mother Generated Index (MGI) in assessment of postpartum quality of life in India" potx

Hóa học - Dầu khí

... limitations of the method used However, the study is limited by the poor ability of the subjects from the LSEC to complete the questionnaire The original mother generated index was modified in the context ... quality of life scores Also, the study was conducted in one district of a big metropolis limiting the generalizability of the results Despite the limitations the study provides useful information on ... contributed to the final version of the manuscript VLB will act as guarantor for the paper Additional material Additional file Mother Generated Index The mother generated index proforma with the suggestion...
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báo cáo hóa học:

báo cáo hóa học:" Pain in cancer. An outcome research project to evaluate the epidemiology, the quality and the effects of pain treatment in cancer patients" pptx

Hóa học - Dầu khí

... collection of information known to be causally associated with the choice of the treatments, then the production of a propensity score (the conditional probability of exposure to a treatment given the ... inclusion to week (day 28 from inclusion) As to the secondary objective of the study (i.e., to evaluate the effects of various therapeutic analgesic options administered by physicians to patients), ... Secondary objectives The database will be used to evaluate the effects of various therapeutic analgesic options administered by physicians - To evaluate the effectiveness of treatment regimens on...
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Báo cáo khoa hoc:

Báo cáo khoa hoc:" Selection of as grandparental combinations a procedure designed to make use of dominance genetic effects" pot

Báo cáo khoa học

... example, the expected genetic merit of the grandoffspring of (1 x 4) x (2 x 6) is the highest, we should select mating pairs 1x44 and x for the propagation of the population The genetic values of these ... chosen to propagate the population SIMULATION Because of the rather intuitive justification of the method given above, the performance of the newly proposed method was checked by computer simulation ... Infinitesimal genetic model The values of the genetic mean of the trait during the first six generations of selection, using the standard procedure and the new method are presented in table III, together...
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báo cáo khoa học:

báo cáo khoa học: "Helping hands: A cluster randomised trial to evaluate the effectiveness of two different strategies for promoting hand hygiene in hospital nurses" ppsx

Báo cáo khoa học

... environment and infection of other patient or HCWs Dissemination of patient flora to the rest of the healthcare environment and infection of other patients or HCWs Touching the patient’s environment ... strengths because of the large numbers of observations and participating wards, the randomisation of wards either to the state -of- the- art strategy or the extended strategy, and the use of unobtrusive ... value of the extended strategy as compared to the state -of- the- art strategy Results from our study will allow us to draw conclusions on the effects of different strategies for the implementation of...
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A mixed methods pilot study with a cluster randomized control trial to evaluate the impact of a leadership intervention on guideline implementation in home care nursing ppsx

A mixed methods pilot study with a cluster randomized control trial to evaluate the impact of a leadership intervention on guideline implementation in home care nursing ppsx

Báo cáo khoa học

... care due to a lack of recognition by practitioners of ischemia or an underestimation of the severity of infections [10] Comprehensive assessments by health care professionals of risk factors are ... study of 37 organizations found leadership to be the only predictor of sustained use of clinical guideline recommendations two and Page of 10 (page number not for citation purposes) Implementation ... 'other staff' to be one of the greatest barriers to nurses' use of research [60] Management behaviours such as support and commitment [56,58,6469], policy revisions [66,70] and monitoring of...
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báo cáo khoa học:

báo cáo khoa học: " A mixed methods pilot study with a cluster randomized control trial to evaluate the impact of a leadership intervention on guideline implementation in home care nursing" docx

Báo cáo khoa học

... care due to a lack of recognition by practitioners of ischemia or an underestimation of the severity of infections [10] Comprehensive assessments by health care professionals of risk factors are ... study of 37 organizations found leadership to be the only predictor of sustained use of clinical guideline recommendations two and Page of 10 (page number not for citation purposes) Implementation ... 'other staff' to be one of the greatest barriers to nurses' use of research [60] Management behaviours such as support and commitment [56,58,6469], policy revisions [66,70] and monitoring of...
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Báo cáo y học:

Báo cáo y học: "How to evaluate the microcirculation: report of a round table conference" potx

Báo cáo khoa học

... also be observed during compression of the tongue (for instance, by the investigators' finger, in an attempt to stabilize the tongue) or during contraction of tongue muscles Interestingly, all ... from to may not have the same implications for tissue perfusion as a change from to 3, which may complicate the interpretation of the effects of therapeutic interventions The two scores can be ... evaluation Adequate choice of optical magnification One may wish to increase optic magnification in order to enhance visualization of some structures (white blood cells) On the other hand, the increased...
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Báo cáo y học:

Báo cáo y học: " A multi-center, randomized, double-blind, parallel, placebo-controlled trial to evaluate the efficacy, safety, and pharmacokinetics of intravenous ibuprofen for the treatment of fever in critically ill and non-critically ill adults" pdf

Báo cáo khoa học

... stratified on the basis of the severity of the patient's condition Randomization envelopes were provided to each site and were opened by the pharmacist in sequential order At the time of randomization, ... died during the 28-day study observation period from conditions related to their critical medical condition at the time of enrollment in the study The laboratory parameters with the most subjects ... patients studied In addition, the duration of exposure was relatively short but none -the- less consistent with the notion that the IV form of ibuprofen would be used only for brief periods in...
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Experimental and numerical investigation to evaluate the performance of triangular finned tube heat exchanger

Experimental and numerical investigation to evaluate the performance of triangular finned tube heat exchanger

Tổng hợp

... numerical simulation across the heat exchanger using three–dimensional model The solution of conservation continuity, momentum and energy equations are used to analyze the flow field inside the heat exchanger ... Governing equations The governing differential equation for the fluid flow is given by Continuity equation or mass conservation equation, Navier Stokes equation or momentum conservation equation and energy ... For the tube of type A, since the inner channel of the insertion is not blocked, its flow cross-section area only differs mildly from that without the insertion While for the tube of type B the...
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Báo cáo y học:

Báo cáo y học: "An innovative method to evaluate the suture compliance in sealing the surgical wound lip"

Y khoa - Dược

... a horizontal plane (one drop over one centimeter of the incision line released from a height of 0.5 cm) This is to evaluate the permeability of each suture on the basis of the uptake of the stain ... too tight On the other hand, if the suture knot is too relaxed, the wound line will not be not sealed enough to prevent infiltration of microbes or other foreign bodies [9, 10] Wound infections ... capable of counteracting bacterial colonization along the suture track [9] Infection is often considered as the worst complication of a sutured wound, and bacteria usually multiply in the area...
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Indoor tests to investigate the effect of brine depth on the performance of solar still

Indoor tests to investigate the effect of brine depth on the performance of solar still

Môi trường

... depth) The objective of this work is to investigate the effect of brine depth on the productivity and efficiency of solar still under laboratory conditions Table shows a summary of some of the studies ... plate of galvanized iron to prevent inflation of the mica as it becomes heated during the operation The three heaters were connected in series to supply a total current of 4.5 A, a voltage of 220 ... and a total power flux of approximately 1000 W/m² to simulate the solar radiation intensity A variac was used to regulate the input voltage to the heaters Figure shows a photograph of the constructed...
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Research report:

Research report: "To study the effect of substituents on the properties of aniline by the method of approximate quantum AM1" pps

Báo cáo khoa học

... Correlation of the dipole moment with the Hammett constants of the substituents It is evident from the table II that electron-donating substituents on the phenyl ring increase the pKa of anilines ... Fugure Correlation of QN with the Hammett constants of the substituents According to the table 2, electron-donating substituents decrease the dipole moment of compounds and electron-withdrawing ... d(CN) The accompanying loss of electron density from the amino nitrogen atom decreases the pKa of the amino group Conversely, electron-donating substituents favor pyramidal sp3 hybridization at the...
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Báo cáo khoa học:

Báo cáo khoa học: " The effect on the small bowel of 5-FU and oxaliplatin in combination with radiation using a microcolony survival assay" pptx

Báo cáo khoa học

... small bowel crypts Therefore, the survival of these clonogens is likely to be a decisive factor in the repair of the bowel after cytotoxic therapy The pioneering work of Withers and Elkind presented ... Therefore, the survival of these clonogens is likely to be a decisive factor in the repair of the bowel after cytotoxic therapy However, it is possible that other factors, such as inflammation and ... 0.007 Conclusion In conclusion, the addition of 5-FU or oxaliplatin to radiotherapy lead to a similar decrease in jejunal crypt survival for both drugs Adding the drugs together with radiation did...
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Image denoising techniques to improve the performance on optical character recognition.

Image denoising techniques to improve the performance on optical character recognition.

Công nghệ thông tin

... external factors such as: ilumination power, photographic speed, transparence level of the lens, the dust in the surface of the documents…Thanks to the association of the factors, we will get the images ... automatical noise reduction The conception of the noise image: The noise image is the phenomenon which the random image points of the images are effected by outside factors Therefore, they’ll creat image ... intensity is the phenomenon which the outside light directly effect on the lens of camera or the surface of the object taken photograph This noise will influence on the image pixels, make the inside...
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báo cáo hóa học:

báo cáo hóa học:" TMD pain: the effect on health related quality of life and the influence of pain duration" pdf

Hóa học - Dầu khí

... Organisation as " an individual's perception of their position in life in the context of the culture and value system of which they live with the relation to their goals, expectations, standards ... From the axis II information, the duration and impact of the pain were assessed The influence of the duration of pain on HRQoL was examined by two means Firstly, the total sample was divided into ... from the department of Oral and Maxillofacial Surgery of the University Medical Center Groningen The group consisted of 95 patients consecutively consulting the TMD/Orofacial Pain section for their...
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Báo cáo y học:

Báo cáo y học: "Surviving meningococcal septic shock in childhood: long-term overall outcome and the effect on health-related quality of life" ppt

Báo cáo khoa học

... abroad; one was untraceable Of the remaining 170 eligible patients, 145 agreed to participate The other 25 patients and/or parents did not respond to the invitation or refused participation on practical ... in the interpretation of the results and writing of the manuscript EMWJ assisted in the interpretation of the results and writing of the manuscript KFMJ initiated this study and assisted in the ... the 90th percentile of the cumulative frequency distribution of the reference groups on a) the CBCL or b) the ASR Youth Self-Report (YSR) ratings of patients aged 11 to 17 years also served to...
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AN INVESTIGATION INTO USING AUTHENTIC MATERIALS TO SUPPLEMENT THE COURSEBOOK ON TEACHING SPEAKING SKILL FOR GRADE – 12 STUDENTS IN GIA BINH II HIGH SCHOOL, BAC NINH PROVINCE

AN INVESTIGATION INTO USING AUTHENTIC MATERIALS TO SUPPLEMENT THE COURSEBOOK ON TEACHING SPEAKING SKILL FOR GRADE – 12 STUDENTS IN GIA BINH II HIGH SCHOOL, BAC NINH PROVINCE

Sư phạm

... how the teachers adapt the lessons to make them suitable for students and whether or not they use authentic materials to supplement their lessons while teaching speaking The scope of the study The ... School The data help to answer the research questions raised above Design of the study The thesis consists of three parts: Part I is the Introduction, which presents the rationales, the scope, the ... ACKNOWLEDGEMENT vii PART I: INTRODUCTION 1 Rationale The scope of the study The research question and objectives of the study Significance of the study Methods of the study Design of the study PART II: DEVELOPMENT...
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