... initial diagnosis The gynecologists will send all their patients the first questionnaire, together with a letter and leaflet to inform them about the study and an informed consent form The letter ... other hospital staff’s interpersonal skills and information provision scale; the exchange of information single-item scale; the waiting time; the hospital access; the comfort single-item scale; ... they received the SCP and whether they believe it has improved the communication between themselves and the gynecologist, and between themselves and their patient Sample size The initial patient...
... the mean change in positive cells between the analyses by the three observers (OB1 t0, OB2 and OB3) When the overall correlations between the analyses of the three observers were calculated the ... 'real' change [20], forthe intra-observer variances was calculated and used to evaluate their disciminatory power The nonparametric Mann–Whitney U-test was used to determine whether each analysis ... Within this setting, reliable and validated methods for studying the ST are pivotal The use of computerized or digital image analysis (DIA) has greatly facilitated the evaluation of ST The major...
... in the hospital setting, their low cost, and their relative safety, make the opportunity to evaluate this class of agents in prospective trials even more exciting These drugs have the potential ... to whether the patient was surgical or medical The survival benefit persisted out to year of follow-up At least one randomizedtrial in critically ill patients with infection has been completed ... growing literature on the benefits of statins, prospective randomized trials are now clearly indicated At least one such trial, conducted by the National Institutes of Health ARDS [Acute Respiratory...
... Pastor's and the other theaters Pastor and the elder Frohman were great pals They called each other by their first names, and the famous old music-hall proprietor was a frequent visitor at the shop ... career IV IN THE NEW YORK THEATRICAL WHIRLPOOL When Charles Frohman went to the Madison Square Theater in 1881 the three Frohman brothers were literally installed forthe first time under the same ... was the only clearing-house in New York for foreign theatrical papers, and to it came Augustin Daly, William Winter, Nym Crinkle, and all the other important managers and critics to get the news...
... Health Service, South Western Sydney Local Health Network, Liverpool, Australia 7Northern Beaches Hospitals, Northern Sydney Local Health Network, Manly and Mona Vale Hospitals, Manly, Australia ... Secondary StrokePrevention in NVAF (developed by MG and JMW) The prevalence of atrial fibrillation Stroke risk and atrial fibrillation (the CHADS2 score) Severity of stroke in patients with atrial ... rheumatic mitral valve disease, or mitral valve replacement, allowing the researchers to exclude these cases as examples of valvular atrial fibrillation Cases of atrial flutter, in the absence...
... one of the four trial conditions and were sent an information sheet about the project and theintervention conditions together with a consent form At this point, however, neither they, their interviewer ... Delivering interventions for depression by using the internet: Randomised controlledtrial British Medical Journal 2004, 328: 34 ICH E9 Expert Working Group: Statistical principles for clinical trials: ... International Journal of Medical Informatics 2007, 76:726-734 Griffiths KM, Christensen H: Internet-based mental health care programs: A powerful tool in the rural medical kit Australian Journal of Rural...
... initiatives—all at predetermined value The current delivery model forces the industry to trade between these values An adversarial and fragmented system will never be able to pull these together It ... general, the user groups focus on how much space they need and their budget, the real estate group focuses on optimizing the capital they have allocated and on ways to lower operational costs Other ... cooperation—represents the challenge This is where owners wield the power as catalysts for industry transformation Owners have the potential to bring together the tribal leaders They can focus these leaders...
... treated, or occur sooner The Economic Argument for Disease Prevention: Distinguishing Between Value and Savings always the same It matters whether the study evaluates the CE of theintervention compared ... Czech Republic.36 The Economic Argument for Disease Prevention: Distinguishing Between Value and Savings Whether prevention can even forestall disease also is questioned The goal of prevention is ... for emphasizing value is not just forprevention but for all of health care A Closer Look at the Issues Reframing the Question: What Saving Money Really Means Health is a good, and goods—whether...
... and power The analyses for Aim three, sustainability and scaling-up of WD practices, proceed logically from the analyses supporting the effectiveness trial of WD Analyses for Aim one: Malleability ... forthe random assignment of both students and teachers Here, we describe the procedures for random assignment in this multilevel trialFor details regarding the effectiveness arm of thetrial ... generally more than offset by the increase in power from growth curve analysis [61] For testing whether theintervention improved teacher practices, statistical power is slightly higher, for the...
... psychotherapy In this trialthe requirements for a low risk of bias (sometimes also termed as “high methodological quality”) are met Randomization, blinding of raters, control of therapy allegiance ... initial response to medication alone [7] Given the long duration of thetrial it would be unethical to keep nonresponsive patients on medication alone for 20 weeks In addition, the focus of the ... approved by the Institutional Review Board/Institutional Ethical Committee (IRB/IEC) of the University of Freiburg and the ongoing trial is under continued review by the IRB/IEC The local IRB/IECs...
... on the composite score and the goals subscale of the Working Alliance Inventory [19] The goals subscale reflects the agreement between therapist and client on what is to be achieved in the therapy ... This is the first randomizedcontrolledtrial to evaluate the therapeutic alliance between patient and therapist in online and face-to-face treatment settings for depression in an experimental design ... investigate the quality of the therapeutic alliance between patient and therapist in an online and face-to-face CBT for depression To our knowledge, this was the first randomizedcontrolledtrial in...
... understands all aspects of thetrial If they agree to enter the trial, they complete a copy of the consent form and send it to the researcher We remind participants that they can withdraw from thetrial ... aspects of thetrial If the participant agrees to enter the trial, she completes a copy of the consent form and sends it to the researcher The second procedure we use is by directly informing the patient ... Mental health and Addiction), Utrecht, The Netherlands 3Department of Epidemiology and Biostatistics, VU University medical centre, Amsterdam, The Netherlands 4Netherlands Center for Occupational...
... test A p-value of < 0.05 was considered significant Further information on statistical analysis is given in the Additional file 4: Statistical analysis The primary efficacy variable was the number ... ] Additional file 4: Statistical analysis Gives the model used forthe statistical analysis and describes how missing data were handled Click here for file [ http://www.biomedcentral.com/content/supplementary/1465-9921-1110-S4.DOC ... this paper MST was the Study Manager for Bayer Healthcare All authors contributed significantly to the development of the manuscript, and all have all seen and approved the final version and take...
... clinical study were incapable of granting informed consent Investigators therefore obtained informed consent from the subject's legal guardian or health proxy before administering the drug Given the ... potential benefit for head injury • The present clinical trial reveals that progesterone may be used as a potential safe drug forthe treatment of acute severe head trauma patients Competing interests ... compiled for all demographic and outcome measures Demographic and clinical data were analyzed using Fisher's exact test The statistical analyses were conducted to assess the differences between the...
... chart showing the retrieval process of clinical trial reports included in the systematic review Table Trial quality of randomizedcontrolled trials with sham acupuncture control Trial ID Risk of ... acupuncture treatment-related information was reported in thetrial by Fink etal [18] Additional file summarizes the treatment characteristics of therandomizedcontrolled trials with sham acupuncture ... to the difficulty in blinding the acupuncturists in clinical trials, most trials blinded the patients or outcome assessors Only three included trials assessed the degree of blinding by asking the...
... We would also like to thank the editorial team of Chinese Medicine for their input and advice Author details Yale Center for Medical Informatics and Departments of Anesthesiology and Genetics, ... scientists analyze some experimental evidence, and deduce that a compound of the herb HS acting on the brain can serve as a potential therapy forthe Alzheimer’s disease In this case, HS targets the brain ... underway in the CM community, e.g the regulatory standards for quality control of Chinese medicinal materials [26] This also brings up the question of how much information needs to be provided for describing...
... (Additional Files and 2) Ethics Approval Ethics approval was obtained from the Committee forthe Protection of Human Subjects at the University of California Berkeley and the PRISMA and Innovations for ... children, and children were also asked for their verbal assent before being included in the study This trial is registered with ClinicalTrials.gov (NCT01047033) Description of theIntervention PRISMA ... rigorously evaluate whether microcredit offers a promising platform for delivering supplemental services Additional material Additional file 1: CONSORT Flow Diagram As described in the Methods section,...
... address their own needs and to resume their former personal and social interests, which is imperative for their own mental health Procedure The project had ethical approval from University of the ... the pre -intervention scores The results are shown in Table The results show that if the baseline scores are controlled for, then the difference between the groups is significant for all categories ... participating relatives in the two groups were requested to complete the FBIS after the completion of psychoeducation in the psychoeducation group Statistical analysis We analysed the data with SPSS...
... prior to its approval Proof-of-concept trials Randomizedcontrolled trials in anti-tumor necrosis factor failure patients The evaluation of novel agents in a more real-world setting, after failure ... several landmark RCTs In these trials, patients with active disease despite DMARD therapy (again typically methotrexate) are recruited as partial responders following an incomplete or loss of therapeutic ... Traditional DMARD Therapy) trial [34], in which 40% had ‘failed’ methotrexate but which also included leflunomide and sulfasalazine among other DMARDs Of importance, these trials have demonstrated...