... during the entirety of their treatment [30] Discussion and conclusion There is currently no panacea for the successful treatmentof SNU, with failures occurring in up to 25% of cases [3,10] The ... was oriented from the dorsal to the volar side at an angle of 30-45 degrees in the frontal plane, and exited the skin 2-3 mm from the tendon ofthe flexor carpi ulnaris muscle These two K-wires ... treatment, due to late presentations The mean duration of SNU at Ilizarov frame application (index procedure) was 13.9 months (range 7-36 months) The location ofthe SNU was in the waist of the...
... linear spline with knots at -60 weeks, the start of Apatone therapy and end oftherapy ( ) indicate where patients went off Apatone or started alternative therapy Table PSA Velocity and Doubling ... Standard therapy was defined to include radical prostatectomy, radiotherapy and hormonal ablation We did not include docetaxol chemotherapy in our inclusion criteria for failure of standard therapy ... total of ten capsules per day Following the 12 week study, two ofthe three “non-responders” in the study who had large body mass index values were given double the dose of Apatone by doubling the...
... occurrence of Buffalo Hump This is the first report on the development of Buffalo Hump in the course of antiretroviral therapy including these drugs: on the basis of our data we can formulate the hypothesis ... scan ofthe cervical region The scan evidenced a massive lipohypertrophy ofthe dorso-cervical region ofthe neck (the maximum diameter identified by focusing up and down through the planes ofthe ... increase of lipohypertrophy ofthe dorso-cervical region ofthe neck There was no localized accumulation of fat in her abdomen and in the submental region of her neck The hump in the back of her...
... gene delivery to the nucleus In the context of gene therapy, the delivery of therapeutic genes by liposomes can also result in the inhibition of angiogenesis and the observation of an enhanced ... would bind the oncogene The target ofthe 246 GENE THERAPY IN THETREATMENTOF CANCER FIGURE 10.4 Diagram of an antisense oligonucleotide, specifically generated based on the sense sequence of an oncogene, ... a “combination therapy. ” Cellular uptake ofthe antisense oligodeoxyribonucleotide appears to be the 248 GENE THERAPY IN THETREATMENTOF CANCER limiting factor for effective therapy In animal...
... overall survival of treated animals (Figure 6D) These results confirm the anti-tumor activity of anti-VLC therapy, as observed by others, and further support the use of anti-CD52 therapy in humans ... therapy twice-weekly for three weeks Therapy was then discontinued and tumor growth was monitored for several weeks Therapy significantly restricted solid tumor growth throughout the course of ... anti-CD52 therapy was initiated one week after the injection of tumor cells Anti-CD52 immunotoxin therapy lead to a delay in the accumulation of tumor-associated ascites and an improvement in the median...
... brachytherapy is performed at relatively few centers in the U.S Balloon-based APBI methods were developed to simplify the brachytherapy procedure The MammoSite™ (MS) brachytherapy applicator was the ... over the operative field, so that the radiation therapy could be delivered without Results The radiation oncologist then broke scrub, attached the XB controller to the catheter, and inserted the ... cc was found to be the proper size, a × cm XB balloon catheter kit was then opened by the OR staff The CED was then deflated and removed and a XB was then inserted in place ofthe CED If a 40 cc...
... chemotherapy, additional therapies include transarterial chemotherapy, ethanol injection, cryotherapy, radiofrequency ablation, and microwave ablation The role of hepatic transarterial therapy ... to 38% The median survival time from the date of diagnosis of metastases was 3.4 years the median survival time from the start of TACE treatment was 1.34 years The median survival time ofthe palliative ... toxicity, and, if the data allowed, the response to therapy Follow-up assessments included a tri-phase CT scan ofthe liver within at least one to two months from thetreatment Evaluation ofthe enhancement...
... with IMRT in their study where they defined the CTV as a part ofthe whole GTV Additionally, the presence ofthe tumor shifted small bowel outside ofthe PTV Many authors reported for other tumor ... maximal dose of 124% inside the PTV This hotspot wouldn’t have been observed if we had covered 95% ofthe volume by 95% ofthe dose Nevertheless, we may wonder whether the presence of these hotspots ... having the effect to increase thetreatment time per fraction [16] Some authors investigated the feasibility of diminishing the size of fields to only irradiate specifically the portion ofthe clinical...
... V20 of 59% and V10 of 73% It is possible that sparing ofthe femoral heads and/ or other organs comes at the cost of increasing dose to the iliac crests The results of our study reinforce the ... M, Pierart M: Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in thetreatmentof locally advanced anal cancer: results of a Page 10 of 11 (page number not for citation ... Contribution of conformal therapy in thetreatmentof anal canal carcinoma http://www.ro-journal.com/content/2/1/41 24 25 26 27 28 29 with combined chemotherapy and radiotherapy: results of a phase...
... significantly, the hematopoiesis recovery time did not significantly differ between the two groups (Table 1) (P > 0.05 using a ttest) There was no durable donor engraftment nor GVHD Therefore the umbilical ... died Therefore, the efficacy rate was 88% The median follow-up time was 35 months (range 13-47 months), and the 3-year overall survival rate was 92% Patients rapidly achieved reconstitution of ... Zhou et al Journal of Hematology & Oncology 2011, 4:27 http://www.jhoonline.org/content/4/1/27 Page of age: 11 years old) Of these patients, 12 were male and 13 were female, and there were 12 patients...
... however, there are reports in the literature of patients developing HAE as late as the ninth decade of life The severity ofthe disease usually improves in the seventh and eighth decades of life ... thickening may be seen CT ofthe abdomen may reveal bowel thickening and ascites with fluid accumulation in the colon, regardless ofthe severity ofthe attack There are three therapeutic goals for ... between the episodic phases The most sensitive and confirmatory test for detection of HAE is the measurement of C4d, a cleavage product of C4, which is abnormal in patients with HAE even when the...
... immunohistochemical profile between these tumours are illustrated in Table Thetreatmentof these tumours is based on surgical resection Postoperative complications consist mainly of hypopituitarism as in the ... consensual protocol has not been assessed because ofthe complex issue of these tumours and the lack of large series In fact, among the 14 cases reported in the literature, eight patients had a benign ... opposition to the SCO, granular cell tumour shows a strong expression of CD68 Besides, the cytoplasm ofthe granular cells is filled with phagolysosomes, and there are no mitochondria The distinction...
... identified the variant, performed the anatomical dissection, created the schematic drawing and reviewed the final version ofthe manuscript OI and AR prepared the draft ofthe manuscript AR improved the ... surface ofthe suprarenal gland; 3) the caudal group, which is made up ofthe sixth to ninth mesonephric arteries which run along to the ventral surface ofthe suprarenal gland [22] The caudal ... forms the arterial plexus ofthe urogenital system [22,23] Despite the fact that any ofthe nine mesonephric arteries can evolve to become the TA, Felix reported that the TA usually derives from the...
... gender or site predilection The size of these tumors is usually smaller than cm; however, the term giant lipoma is preferred when the size exceeds cm Our patient had a tumor of more than 11 cm in diameter, ... and interpretation of patient data regarding the histopathologic disease AVV performed the histologic examination and helped in preparation ofthe final manuscript PRM did the transperitoneal ... case report and accompanying images A copy ofthe written consent is available for review by the Editor-in-Chief of this journal Author details Department of Pathology, Laboratory Medicine, Transfusion...
... for any of these modalities There are some individual studies, however none show unequivocal proof of efficacy or effectiveness cisely The promoters also claim that the metal surface ofthe instruments ... involve the use ofthe patented form of instrumented-assisted soft tissue massage/mobilisation The treating student will initially scan the area for notional "muscle adhesions" usingthe Graston ... be" at the other Participants are asked to indicate which point along the line best represents their pain intensity The distance from the no-pain end to the mark made by the participant is their...
... around the world to search for new therapeutic options [5]; one of these options involves the use of Dendritic Cell (DCs) immunotherapy Clinical trails based on DCs have been conducted for thetreatment ... one-third of these patients progress to incurable metastatic disease, for which there are few treatment options The chemotherapy currently used has limited efficacy [3,4] This lack oftreatment ... Vaccines and Therapy 2008, 6:2 cific antigens (PSA), the south and southeastern regions of Brazil are expected to exhibit the highest incidence Seric PSA level has aided in the diagnosis of very small...
... deleted from the risk:benefit analysis In some cases a medication with greater side effects or medical risk may be the preferred treatment because ofthe documented efficacy ofthe agent either in ... renal disease are on the rise [65] As more of our patients develop renal disease, psychiatrists must be aware ofthe effects of psychotropics on the kidneys, as well the effects of decreased renal ... mortality [6-9] The authors concluded that the prevalence of obesity in this study of outpatients was related to the use of antipsychotics, but less so lithium or anticonvulsants Of those persons...
... angles ofthe dural opening The most significant step involves constructing small supporting pillars on the bilateral sides ofthe vessels as they pass the edge ofthe dural window (the pillars ... patient populations are small, these experiences are valuable At present, in the absence of definite proof ofthe efficacy of decompressive craniectomy in thetreatmentof TBI, such as from multicenter, ... the base backwards along the zygoma but left the fascia base 1-2 cm long for the blood supply Finally, they turned the temporal fascia beneath the temporal muscle and sutured it to the dura They...
... 100% relief of their pain in 86% ofthe patients with a median relief period of months The range of relief varied from zero days to up to 13 months for the facet injection group None ofthe lumbar ... that the direct visualization ofthe joint allows better de-innervation ofthe joint and removal ofthe entire end-plate receptors that adhere to the bone and capsular tissue Limitations ofthe ... improvement from the radiofrequency procedure, the length of improvement varied from months to 16 months Again, no one in the radiofrequency group developed permanent relief of their pain Thus, the endoscopic...