... on the SH groups ofthe substrate andthe catalytic Cys89, which is conserved throughout the thiolase superfamily The results obtained indicate that thesulfur atoms of both the enzyme andthe ... ¨ The catalytic cavity lies at the bottom ofthe pantetheine-binding tunnel The terminal oxygen of OPP is ˚ 5.2, 7.4, 6.2 and 7.6 A away from thesulfur atoms of Cys89, Met288, and Cys378 and ... the oxidation state ofthe catalytic cysteine Binding mode of CoA to the C89A thiolase variant To better understand the importance ofthesulfursulfur interactions in the catalytic cavity of...
... upon the details ofthe method of analysis In the analyses other than U, the cellulose is excluded in calculating the calories Nutrient ratio is the proportion ofthe sum ofthe carbo-hydrate and ... comprised in the other two classes, and cannot well be excluded from consideration Water forms an essential part of all the tissues ofthe body It is the solvent and carrier of other substances ... in sodium chloride and other salts that the addition of common salt is unnecessary An excess ofthe latter excites thirst and spoils the natural flavour ofthe food It is the custom, especially...
... for the pyrolysis and combustion of these fuels, for which there is lack of information in the literature The obtained data should be useful for the design of furnaces, which will utilize these ... cj is the fraction of combustibles in component j, aj(t) is the reacted fraction of component j in time t and m∞ is the normalized amount ofthe solid residues (minerals) at the end ofthe experiment ... Ej is the activation energy of component j, g expresses the effect of ambient gas composition and f describes the change of surface reactivity as a function ofthe fractional burn off: As the function...
... the piece of discourse under analysis The later includes the type of communicative event, the topic, the purpose ofthe event, the setting, the xii participant andthe relationships between them ... medium ofthe language activity It is the manifestation ofthe nature ofthe language code being used Halliday and Hassan include here: “Mode is the function ofthe text in the event, including therefore ... renovation cause and to raise its economy's competitiveness on the one hand, and on other hand to affirm the consistency ofthe Party and State's policies to integrate the national economy into the world...
... to the bulge ofthe equator Many forms of life on the coast are tailored to the cycle of tides High and low The gravitational pull ofthe Moon on the Earth causes tides in the oceans and seas of ... motion, due to the rotation ofthe Earth, the gravitational pull ofthe Sun and Moon, andthe difference in temperature and salt content ofthe water These movements form strong currents in the oceans, ... gravity and formed the Sun, the dust and particles around it clumped together to form the planets The heat ofthe Sun melted the ice particles nearby and eventually these rocks grew larger to form the...
... may provide the competent authorities the authority to inform the right holder ofthe names and addresses ofthe consignor, the importer andthe consignee, andofthe quantity ofthe goods in ... into the Party's territory of copies ofthe work; B the first public distribution ofthe original and each copy ofthe work by sale, rental or otherwise; C the communication of a work to the public; ... BETWEEN THE UNITED STATES OF AMERICA ANDTHE SOCIALIST REPUBLIC OF VIETNAM ON TRADE RELATIONS The Government ofthe United States of America andthe Government ofthe Socialist Republic of Vietnam...
... the operational status ofthe system The types of tests selected andthe frequency in which they are conducted depend on the importance ofthe system andthe resources available for testing These ... fill the gap between the state ofthe art in system development and actual operation of these systems Two, security testing is important for understanding, calibrating, and documenting the operational ... for the testing organization to alert other security officers, management, and users that network mapping is taking place Since a number of these test mimic some ofthe signs of attack, the appropriate...
... contradictory to the conclusions ofthe Final Document ofthe Moscow Meeting ofthe Conference on the Human Dimension ofthe CSCE and in breach of Article 19 ofthe International Covenant on Civil and Political ... or the economic well-being ofthe country, for the prevention of disorder or crime, for the protection of health of morals, or for the protection ofthe rights and freedoms of others Finally, the ... for the outbreak of conflicts andof their prevention, settling and dealing with their aftermaths The development of democratic institutions andthe protection of human rights are among the OSCE’s...
... membrane and mediate interactions with the cytoskeleton and with signaling molecules On the basis of extensive searches ofthe human and mouse genomic sequences, it is now known that 18 a-subunits and ... conformation and biological function For example, only N-glycans located on either the b-propeller of a5 [55] or the I-like domain of b1 or b3 [68] contribute to the regulation of integrin function Therefore, ... Downregulation ofthe alpha-Gal epitope expression in N-glycans of swine endothelial cells by transfection with the N-acetylglucosaminyltransferase III gene Modulation ofthe biosynthesis of terminal...
... sense and antisense strands ofthe piRNA hairpin are involved in formation ofthe piRNA-interacting complex (piRC) and function in the transcriptional gene silencing of retrotransposons and genetic ... positions and sequences used to amplify pri-miR9-1, 9-2 and 9-3 Arrows indicate the position and orientation ofthe primers Bold font represents the sequence of mature miR9* and italic fonts the sequence ... vector The promoter sizes ofthe construct are indicated by numbers in parentheses )44 means located 44 bp upstream ofthe first base pair at the 5¢-end of pre-miR-9-1 defined as +1 FLuc is the ORF of...
... interactions between the peptides andthe Grb4 SH2 domain The affinity ofthe binding interactions was evaluated by measuring the changes of fluorescence polarization ofthe peptides at each step of titration ... from the differences ofthe 13Ca and 13Cb chemical shifts ofthe We next address the questions of whether secondary tyrosine phosphorylations would affect the Grb4 SH2 domain binding to the ephrinB2(301–333)-pY304 ... Taken together, both the NMR and fluorescence polarization experiments Table The effect of tyrosine phosphorylations on the binding affinity of ephrinB2(301–333) to the SH2 domain of Grb4 and to the PDZ...
... ATnI130)252, and ATnI232)292 did not migrate into the gels, while free ATnI-52K and ATnI1)128 exhibited a band near the origin and at the middle ofthe gel, respectively The bands corresponding to the ... PAGE Lanes a and d, in the absence of both TnC and Ca2+; lanes b and e, in the presence of TnC andthe absence of Ca2+; lanes c and f, in the presence of both TnC and Ca2+ Ac, actin; Tm, tropomyosin; ... actin and TnC in the absence and presence, respectively, of Ca2+ These phenomena should directly reflect the mechanism of Ca2+ switching involving the alternative binding ofthe C-terminal region of...
... LPO and MPO They deal with thethe major importance of catalase activity in MPO with respect to LPO, the different sensitivity ofthe enzymes to Cpd III inactivation andthe redox potential ofthe ... in the presence of H2O2 alone, a non-physiological condition We believe that the absence of direct evidence ofthe radical in the presence of cosubstrates limits the validity of extrapolating the ... oxidize them [19] On the other hand, this fact does not represent proof ofthe presence of one or two oxidizing equivalents on the decay product of Cpd I The EPR spectrum of a spin-trapped radical...
... context, they exceed the percent rate of return suggested for government programs by the Office of Management and Budget; they also exceed the historic real rate of return in the stock market of approximately ... implementation site, and also among families within a single program site.190 The intensity ofthe services provided, the skills ofthe home visitors, andthe content ofthe home visiting curriculum ... to meet the needs of working parents Furthermore, states should welcome a diverse set of providers that meet quality standards andthe needs ofthe parents and communities they serve Business...
... expedition and to offer it to "the Sun whom they called father and to the earth their mother." They severed its head and raised this as though offering it to the sun They then tilled the earth where the ... another to Oco-telulco, the third to Tizatlan andthe fourth to Quiahuiztlan, that is to say, the men ofthe Mountains, the men ofthe Limepits, the men ofthe Pinetrees, andthe Watermen; all these ... the lord ofthe North, and designates it as the name of one ofthe four principal and primitive gods ofthe Mexicans The commentator ofthe Telleriano-Remensis Codex, moreover, records that these...
... one hand, and on the other by the attitude ofthe speaker towards the message andthe addressee "Thus into the domain ofthe organization of utterance pertains all that is connected with the processual ... upon the face ofthe deep; andthe spirit of God moved over the waters And God said: Be light made And light was made And God saw the light that it was good; and he divided the light from the ... darkness And he called the light Day, andthe darkness Night; and there was evening and there was morning one day." (Douay Version, 1610) "In the beginning, when God created the heavens andthe earth,...
... Academy of Sciences to secure the services of eminent members of appropriate professions in the examination of policy matters pertaining to the health ofthe public The Institute acts under the responsibility ... setting the stage for another swing ofthe pendulum back to the latter as a result of disappointments with the results of diffuse grassroots investments ofthe 1970s In the early 1980s the USAID ... of Sciences, the National Academy of Engineering, andthe Institute of Medicine The members ofthe committee responsible for the report were chosen for their special competences and with regard...
... Francistown to cater for the needs ofthe people in the northern part ofthe country (including Palapye), and one in Gaborone catering for the needs of people in the southern part ofthe country If, for ... conditions of poverty from a very early age and some of these children were born to single mothers The caregivers are mostly from their mother’s side ofthe family and are often grandparents ... and they assist with the identification of orphans and provide psychosocial support to them One ofthe strengths ofthe orphan care programme, as identified by the caregivers, is the supply and...
... petitioned the court to rehear the case andthe final outcome of these and had yet to be determined at the time of this report’s publication In 2007, EPA’s Office of Water (OW) initiated the aforementioned ... Montana andthe Dakotas are part of Region as well, these states have some distinct features Most of Montana has characteristics ofthe Rockies, but the eastern areas of both Montana and North ... however, are not often fully addressed in NEPA documents due to the difficulty in understanding the complexities of these impacts, a lack of available information on their consequences, andthe desire...