... during the acute phase of infection In conclusion, our findings provide new insight into theroleof PTX3 in acute alphaviral infection The newly identified roleof PTX3 in enhancing RRV infection ... against a number of viruses, including influenza virus [30], human/murine cytomegalovirus [7] and coronavirus murine hepatitis virus [53], in contrast to the pathogenic role identified inthe ... Taken together, these data indicate that the N-terminal domain of PTX3 is responsible for the binding interaction with RRV and its functionality in facilitating viral entry Discussion Robust innate...
... codification ofthe CBD marks the same tendency of defining the expanding sovereign rights of States over their GRs, even including the information contained therein The expansion of IPRs from inanimate ... above) consisting ofthe freedom of appropriation of GR and of TK on the part ofthe inventor on one side, while on the other the users inthe country in question had to purchase the secondary ... the Law ofthe Sea: Rethinking the Current Legal Dilemmas” (1981) 18 San Diego Law Review 415 K Baslar, The Concept ofthe Common Heritage of Mankind in International Law (Martinus Nijhoff, The...
... provisions ofthe law by increasing the activities of law enforcementagenciesin other coordinating relations with the people’s public security on theenforcementofintellectualproperty rights having ... acts of infringement of related rights (Article 28 of Law on Intellectual Property) ; acts of infringement of industrial property rights (Article 126, 127, 129, 130 of Law on Intellectual Property) ; ... accidentally or intentionally infringe theintellectualproperty rights; - Those people who infringe theintellectualproperty rights must have civil capacity; Some casesin which limitations of intellectual...
... enabling of others to help achieve the goals ofthe organisation Furthermore, the ability to control others is given no prominence in this recent definition of leadership A brief reviewof early ... philosophy underpinned the birth ofthe behavioural theories of leadership inthe 1930s and the perspective began to move from a belief inthe inborn characteristics of leaders, to a focus on behaviour ... raising the profile of women in management However, during this period of research, there was an emerging recognition ofthe importance of a concern for people inthe behavioural theories as being...
... years, foreign financial institutions, mainly foreign banks have played an important roleinthe opening up of Chinese financial industry Inthe early days of their operation in China, foreign banks’ ... price The trade of inter-bank bond market relies on the securities booking system ofthe CGSDTC and the bond trading system ofthe inter-bank lending centre The trading system ofthe national inter-bank ... source of financing for enterprises, if their own capital is excluded In summary, the deepening process ofthe financial markets has rendered the dominance ofthe banking sector inthe financial...
... explore the sources ofthe heterogeneity inthe efficacy ofthe BCG vaccine reported inthe individual studies Using a model that included the geographic latitude ofthe study site and the data ... adults (39 ) The renewed interest in examining the indications for BCG vaccination inthe United States included consideration ofthe wide range of vaccine efficacies determined by clinical trials ... induration after skin testing with TU of PPD tuberculin The Tice strain of BCG is administered percutaneously; 0.3 mL ofthe reconstituted vaccine is usually placed on the skin inthe lower deltoid...
... banks in making small business loans Loan officers at small banks can take into account a wide variety of factors in reviewing applications for small business loans, including the character ofthe ... counties inthe near future using more recent data 5In Charts 3-5, the size categories are not adjusted for inflation and are based on the size ofthe bank rather than the size ofthe banking organization ... change in small business lending due to themerger is likely to be swamped by unrelated changes in lending inthe rest ofthe bank Studies that disagree with the majority view that the absorption of...
... cost-effective way of assessing health risks; • the identification of all risk points along the chain of events fromthe origin ofthe wastewater to the consumption ofthe produce (e.g the farm-to-fork ... Figure 19 inthe timing and intensity of rainfall, or the period of time without rain, as well as affecting the quality of water in rivers and lakes through changes inthe timing and volume of peak ... Hoepner,2008) There is scope to improve the sustainability ofthe desalination process The process results inthe discharge of a concentrated brine into the receiving waters Temperature and salinity...
... cells were maintained in a hypoxia chamber (Invivo 400; Ruskinn Inc., Cincinnati, OH, USA) constantly maintained at 1% O2 Culture medium was replaced every other day inside the chamber For miRNA ... initiated at 48 h post-transfection by maintaining the cells in culture medium containing 2% horse serum Cells were fixed on day of differentiation and stained with hematoxylin and eosin One of ... relevant roleof miR-27 inthe regulation of adipose tissue functions in vivo, we examined the expression of miR-27 inthe genetically obese ob ⁄ ob mice The 2352 expression levels of both miR-27a...
... through the exchange between subunits of either their N-terminal, or their C-terminal ends [33–35] We found that the behavior with the model membrane ofthe dimer in which the C-terminal ends ... Nter are the C-terminal and N-terminal structural regions, respectively, ofthe two A and B monomers ofthe dimeric RNase The black circle between the monomers indicates the mass center ofthe dimer ... contribution ofthe protein to the degree of polarization ofthe fluorescence probe Leakage of vesicle aqueous contents induced by the RNases was measured by the 1,3,6-trisulphonate-8-aminonaphtalene...
... were used for measurement ofthe remaining [3H]GABA and [14C]sucrose The protein concentration inthe supernatant was determined using the bicinchoninic acid protein assay reagent (Pierce, USA) ... previous work using the expression system ofthe Xenopus oocyte [7] In order to exclude the possibility that the reduction in function inthe mutants could be due to a reduction inthe number of ... N-linked oligosaccharide side-chains are important for the GABA transport activity 1-Deoxymannojirimycin inhibits the GABA-uptake of GAT1 In order to gain further insight into theroleof the...
... basis ofthe discussion I t is thein interaction ofthe results of these asynchronous processes that the process of comprehension is defined 4.1 The processes are independent ofthe knowledge representations ... results Because ofthe parallel activation of a l l meanings of each recognized word in HOPE, the determination ofthe phonetic representation of a recognized word determines the breadth of active ... slowing of processing relative to on-line word recognition Studying the results of such "lesions" and their occurrence or not in pathological behavior is used to further understanding of the...
... Adjustment and theRoleof Bank Credit in Russia: Evidence from a 420 Firm's Qualitative Survey The main underlying question inthe above-mentioned conclusions rather brings back to the issue of ... side ofthe Graph does not reflect an internal adjustment but rather some exogenous characteristics ofthe sample 14 These phenomena are generated in a model of soft budget constraint in Berglof ... ô ằ (increase in indebtedness) by 15 points (33 minus 18), and increases the probability of Expected-Debt to be equal to ô ằ (not indebted and not going to be) by 13 points (34 minus 21) THE ACTUAL...
... many of them have been pioneers inthe Latin American microfinance industry As of today, out of 15 Latin American members are active in microfinance These members are involved in different ways in ... microfinance stands unrivalled in scale, and outreach continues to grow in terms ofthe number of microborrowers Institutions providing microfinance in Asia play a critical rolein increasing the ... benefit from insurance Thus, the importance ofthe microfinance movement today is the result of an enlarged vision of banking – where financial inclusiveness plays an important rolein social...
... deliberately confused customers, damaged the owner’s business and the infringing business has thus benefited fromthe reputation and goodwill associated with the mark Inthe UK the legal action used to ... arising fromthe seminars, which I have been presenting, on the commercial exploitation ofintellectualproperty assets by licensing, under the auspices of Thorogood Publishing since 1988 The theme ... slower, the effectiveness ofthe initial balancing is diminished; • The out of balance component must be removed fromthe machine, installed inthe balancing machine to correct balance, and then...
... inherent inthe visual scene Specifically, the more ambiguous the meaning ofthe visual image, the more influence is exerted by the musical score inthe process of interpreting the scene Music can ... the relationship is invertible without changing the perceived meaning (i.e., it is equally valid to say that the music projects the meaning ofthe image or the image projects the meaning ofthe ... Borrowing fromthe field of linguistics, Gorbman applies the term “ commutation” to describe the capability of music to influence the meaning of a film in this way (1987, p 16) As an example of the...
... formation ofthe oxazolinium ion intermediate; (C) Hydrolysis ofthe oxazolinium ion intermediate Copyright National Academy of Sciences, USA questioned on the basis of studies of chitinase A from ... However, the mechanistic roles of several of these residues are not described well and there is no example of mutational analysis of all of these residues inthe same enzyme To obtain an insight into ... this role, explaining the residual activity ofthe D215N mutant The possibility to interact is obviously lost inthe D215A mutant which in fact is one ofthe least active mutants described in this...
... properties ofthe document containing the sentence and properties ofthe sentence itself Regarding the former type, two features come into play: the relevance score ofthe document (from the IR engine) ... evaluating answers to definition questions In HLT/EMNLP 2005 J Lin and D Demner-Fushman 2006a Theroleof knowledge in conceptual retrieval: A study inthe domain of clinical medicine In SIGIR ... acquiring nuclear weapons?”, which are the focus ofthe AQUAINT program inthe U.S., and opinion questions such as “How does the Chilean government view attempts at having Pinochet tried in Spanish...
... whereas the slope ofthe slow semi-inactivation process was rather similar to the slope ofthe curve found when the medium did not contain AdoMet, with an estimated halflife of 10.5 Theroleofthe ... are located inthe central domain of each subunit, inthe interface between the two dimers comprising the tetrameric structure [29] This domain contains five cysteine residues, two of them (Cys35 ... forming a disulfide bond which may be necessary for the tetrameric state ofthe enzyme In addition, Cys69 is involved inthe correct folding ofthe monomer, supporting the establishment of the...
... additional schooling, the estimated schooling effect could include both the impacts of schooling and the fact that those continuing in school could earn more inthe absence of schooling.2 For the most ... student in a school in Ghana or Peru would gain the same amount of knowledge in any year of schooling as the average student in a school in Finland or Korea? Still, using the quantitative measure of ... scores 28 using the mathematics component ofthe transformed and extended tests shown in Figure 4.1, replicating and strengthening the previous results by using test data from a larger number of countries,...