the public switched telephone network is designed to be available 99 999 of the time
Báo cáo khoa học: Probing the catalytic potential of the hamster arylamine N-acetyltransferase 2 catalytic triad by site-directed mutagenesis of the proximal conserved residue, Tyr190 pot
... corresponding to the pKaacetyl of the active site Cys. This unchanged pKaacetyl of the activesite Cys in Y190F could be ascribed to dipole–dipoleinteraction between the para-hydrogen of Phe and the aspartyl ... TS-I). If, however, the pKatransacetyl of the His is significantly lower than that of the conjugate acid of the attacking arylamine, thendeprotonation is favored to follow the tetrahedral inter-mediate ... His107 (Fig. 1). ThisTyr is highly conserved [34–36] in all the NAT sequencesreported to date, with the only exception being the iso-form banatB from Bacillus anthracis, where a His is atthe...
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Tài liệu GPON Migration Ensuring my Network is Ready to Migrate to GPON doc
... will the network migrate from one PON flavor to the next as bandwidth demand continues to rise.GPON MigrationEnsuring my Network is Ready to Migrate to GPON Ensuring my Network is Ready to ... characteristics – but they may also be quite different. The spectral attenuation refers to the loss of a signal as a direct correlation between the wavelength and the distance traveled. The lower the ... design. This applies equally to overbuilds, Greenfield applications, or even a migration network. To be profitable, it’s imperative to understand the impact of the decisions made early in the planning...
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Báo cáo khoa học: In vitro gamma-secretase cleavage of the Alzheimer’s amyloid precursor protein correlates to a subset of presenilin complexes and is inhibited by zinc potx
... different mechanisms to control the aggregationstates of these substrates and supports our originalhypothesis that mammalian cellular factors enableendogenous proteins to be presented to the c-secretasecomplex ... thenligated into the HindIII ⁄ BamHI site of p3XFLAG-CMV-14and the resulting vector named SPC99-3FLAG. The follow-ing primer pairs were used to amplify the C99-3FLAGsequence from SPC99-3FLAG: ... zinc-bind-ing domain may be present in the Ab sequence of C99,we hypothesized that zinc may affect the oligomeriza-tion state of C101-3FLAG. Therefore, the molecularmass of C101-3FLAG before and after...
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Báo cáo Y học: Barley a-amylase Met53 situated at the high-affinity subsite )2 belongs to a substrate binding motif in the bfia loop 2 of the catalytic (b/a)8-barrel and is critical for activity and substrate specificity pot
... view of the global structure of the AMY2 (top) and TAA (bottom) complexes[16,17]. The inhibitors are in green and the arrow indicates the nitrogen(in dark blue) that corresponds to the oxygen of ... characterize the number of recognizedsubstrate glucosyl residues, the binding affinity of individualsubsites, and the position of the bond to be cleaved [31–34]. The spatial distribution of binding ... the transglycosylation/hydrolysis ratio of that enzyme. Thisexplanation may also apply to the AMY1 mutant,although the shape of the binding cleft of S. fibuligeraa-amylase is very similar to that of TAA [60]...
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báo cáo sinh học:" Empowering health personnel for decentralized health planning in India: The Public Health Resource Network" ppt
... Health Resource Network is an efforttowards this end.Discussion The Public Health Resource Network Started in 2005, the Public Health Resource Network (PHRN) is an innovative distance-learning ... decentral-ized governance of systems of planning and delivery, atleast at the level of the district. In India, a district is the smallest administrative unit. The country has 604 districtsacross its ... managerstowards strengthening the public health system in theirdistricts, and assisting in the emergence of state and dis-trict resource groups for this purpose;ã empowering civil society to create...
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Comparing the cultural and linguistic analysis of the English word “meal” and words relating to it in contrast with Vietnamese equivalents.
... rice, the guest often stops and says he or she is full even if s/he is starving. To respond thoughtfulness towards the host, the guest can serves alittle of the other dishes to another to family ... teaspoonful for the pot. Boiling water is poured into the pot and the tea is left for about five minutes before the host serves the guest.Even there are the adages from the side of the Victorian about ... vestigial the presence of the napkin is, because the purpose of table manners is to preserve cleanliness and proper appearance. Assoon as the meal is served, the diners remove the napkin from their...
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Tài liệu Báo cáo " STABILITY OF THE ELASTOPLASTIC THIN ROUND CYLINDRICAL SHELLS SUBJECTED TO TORSIONAL MOMENT AT TWO EXTREMITIES " pptx
... givenin table 1. The calculating results based on the elastic theory are presented in table 2. Figure1 is graph of the elasto-plastic instability case . The comparison between the elasto-plasticinstability ... on the theory of elastoplastic p rocesses the above mentionedproblem has been solved by approach simulation of instability form of the cylinder (see[1],[5]). In this paper, the solution of ... based on the elastic theory is reliable.c) The expression of deflection δw in (3.1) has exactly described real bending form of structure.This paper is completed with financial support from the National...
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Tài liệu Báo cáo khoa học: P25a ⁄ TPPP expression increases plasma membrane presentation of the dopamine transporter and enhances cellular sensitivity to dopamine toxicity pptx
... cells sensitized them to the toxicity of extracellular dopamine. Neuronal expression of p25a thusholds the potential to sensitize the cells toward dopamine and toxinscarried by the dopamine transporter.Structured ... neurons of the sub-stantia nigra pars compacta is responsible for the major motor symptoms of PD. The neurotransmitterDA has been hypothesized to play a major role in thisselective loss of dopaminergic ... risk of oxidative stress, as DA can auto-oxidize at the neutralpH of the cytosol and thereby form toxic DA-quinonespecies, superoxide radicals and hydrogen peroxide. The low pH in the DA storage...
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Tài liệu Integrative Medicine and the Health of the Public: A Summary of the February 2009 Summit docx
... This publication is the product of the efforts of many individuals, and the Institute of Medicine (IOM) is grateful to all who contributed to the success of the summit. Recognition ... members are drawn from the councils of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine. The members of the committee responsible for the ... well-being throughout the life span. This is the background to the IOM’s Summit on Integrative Medi-cine and the Health of the Public. Integrative medicine may be described as orienting the...
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Tài liệu Báo cáo khoa học: Identification of differentially expressed genes of the Pacific oyster Crassostrea gigas exposed to prolonged thermal stress docx
... constitutive isoforms of HSP70 aresynthesized in the gills and mantle of C. gigas [26]. The expression level of the constitutive forms increasesafter thermal stress, whereas the inducible one is expressed ... amplication efciency of the target orgene of interest, Eref is the amplification efficiency of the reference (ribosomal 18S) and Ct is the crossing threshold.Statistical analysis The variations in ... exposed to a temperature slightly above the upper natural watertemperature in the area. Our study is the first to applyan overall genomic approach to the study of the response of C. gigas to prolonged...
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Tìm thêm: xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam mở máy động cơ lồng sóc các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008