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the law of conservation of energy states that the total amount of energy in the universe is

Báo cáo khoa học: Identification and characterization of four novel peptide motifs that recognize distinct regions of the transcription factor CP2 doc

Báo cáo khoa học: Identification and characterization of four novel peptide motifs that recognize distinct regions of the transcription factor CP2 doc

Báo cáo khoa học

... apreponderance of histidines, implying the importance of this amino acid residue in the CP2-binding motif of proteins that interact with CP2. Indeed, two orthree histidine residues are found around the HXPRmotif ... althoughtheir physiological functions and roles are well charac-terized. Of the proteins that have CP2-binding motifs, wefurther investigated the CP2 binding of the twoHXPR-motif-containing proteins, ... CP2-interacting peptides and discovered that they containedsome new motifs that play an important role in the interaction between CP2 and its binding proteins.ResultsIsolation of CP2-binding...
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Federal Reserve Bank of Dallas Globalization and Monetary Policy Institute - Ultra Easy Monetary Policy and the Law of Unintended Consequences* pptx

Federal Reserve Bank of Dallas Globalization and Monetary Policy Institute - Ultra Easy Monetary Policy and the Law of Unintended Consequences* pptx

Ngân hàng - Tín dụng

... increasehasbeennotable,72This is nottodenysuccessfuleffortsbyanumber of countries,includingChina,toexpandmarkets in otherEME’s. Of coursethisstillleaves the broaderquestion of the robustness of the totality of thosemarkets in the event of aseriousdownturn in the AME’s.73Thisproblem is analogousto that facedbyJapanesecorporations in the 1990’s,aftermanyyears of debtfinancedinvestmentwhichprovedunprofitable.Koo(2003)stronglycontends that the weakness of investmentspending in Japan in the 1990’swasduetothis“balancesheeteffect”,andwasnotduetoashortage of loanscausedbyaweakenedbankingsystem.74SeeBIS(2012)p29forafullerdocumentation.AlsoseeMcKinsey(2010)whoidentify the householdsector in five of the fourteencountriestheyconsiderashavingahighprobability of futuredeleveraging.TheyidentifySpain, the US, the UK,CanadaandKorea.While the householdsectors in Brazil,Russia,ChinaandIndiawerenotjudgedtobeoverleveraged,note that the dataconsideredextendedonlyto2009.Thus the reportmissed the recentsharpincreases in householddebtlevels in thosecountries.45TettG(2012)“Sizecanbedeadly in alowrateworld”FinancialTimes17MayTurnerP.(2011) Is the long‐terminterestrateapolicyvictim,apolicyvariableorapolicylodestar”–BISWorkingPaper367,Basel,DecemberWaldropM.M.(1992)“Complexity”–LemonandSchusterPaperbacks–NewYorkWedelJR.(2009)“ShadowElite”–BasicBooks,NewYorkWhiteW.R(2004)“Arechanges in FinancialStructureExtendingSafetyNets?”–BISWorkingPaper250,BaselWhiteW.R(2006a) Is PriceStabilityEnough?”–BISWorkingPaper205,AprilWhite ... when106 The flattening of yieldcurveshasalreadyledtoanarrowing of interestspreads.SeeBankforInternationalSettlements(2012)TableVI.1107SeeBillGross(2012).This is particularlyperniciousifitthwartslongertermlendingtofund the longerterminvestment that manyAME’sreallyneed.108SeeMeyer(2012)109SeeHaddockandBarnes(2012).Theycontend that, priorto2007,manyhighlyleveragedpropertydeals in the UKusedswapstominimize the risks of risingfinancingrates.Indeed,many of theseswapshadamaturitylongerthan the underlyingloanitself.Nowmany of thesedealsneedtoberestructured,butlowpolicyrateshaveraised the cost of breaking the swaptoprohibitivelevels.This is anotherexample of howlowpolicyratescanimpede the purging of malinvestments in the downswing of the creditcycle.110Theseareverysimilarto the implicationsforpensionfundswhichwerediscussedabove.111Dickson(2001)112Antolinetal(2011),Frenchetal(2011),StandardandPoors(2011)andRamaswamy(2012)18closely ... Misallocations in the creditdownswing75Increasedspendinggenerallyresults in moreproduction,butnotnecessarily.Supplyresponsiveness in the constructionindustry in factvarieswidelyacrosscountries.Forexample, the response in terms of newhousingstartswasmuchgreater in the USthan the UK,dueto the verystrictplanningandzoningrestrictions in the latter.76SeeKPMGGlobal(2012)77SeeEuropeanChamber of Commerce in China(2009). In presenting the report, the President of the Chambersaid“Ourstudyshows the impact of overcapacity is subtlebutfarreaching,affectingdozens of industriesanddamagingeconomicgrowth,notonly in Chinabutworldwide”.Note that thiswaswrittenbefore the furtherspurt in investmentspending in 2010.44Rajan...
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Development of a Regional Risk Management Framework for APEC Economies for use in the Control and Prevention of Introduced Marine Pests

Development of a Regional Risk Management Framework for APEC Economies for use in the Control and Prevention of Introduced Marine Pests

Báo cáo khoa học

... NACA to enhance the effectiveness of existing instruments within APEC Institutional arrangements for managing the marine environment is fragmented in most economies Baseline surveys to ... FrameworkConclusions, including the results of the November 2001 Workshop Management Framework - Introduced Marine PestsManagement capabilities and approaches APEC and the MRCWG have a role in liaising ... Framework - Introduced Marine PestsBackgroundWithin APEC little is known on the introduction of marine pestsLittle practical information on measures to prevent introductionsLack of knowledge...
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Tài liệu Consequences of Voluntary and Mandatory Fair Value Accounting: Evidence Surrounding IFRS Adoption in the EU Real Estate Industry docx

Tài liệu Consequences of Voluntary and Mandatory Fair Value Accounting: Evidence Surrounding IFRS Adoption in the EU Real Estate Industry docx

Kế toán - Kiểm toán

... estimation of the logistic model in Table 3 Panel B examining the determinants of firm i’s provision versus non-provision of investment property fair values in the pre-IFRS period; NO_FV_PRE an indicator ... appraisers, either external (that is, independent appraisal firms hired by the investment property firm) or internal (that is, qualified individuals within the investment property firm). The UK is noteworthy, ... cost of capital. We then examine whether the adoption of IFRS reduces or eliminates these previously documented differences in information asymmetry, owing to the now mandatory provision of investment...
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Tài liệu Báo cáo khoa học: Crystal structure of thiamindiphosphate-dependent indolepyruvate decarboxylase from Enterobacter cloacae, an enzyme involved in the biosynthesis of the plant hormone indole-3-acetic acid doc

Tài liệu Báo cáo khoa học: Crystal structure of thiamindiphosphate-dependent indolepyruvate decarboxylase from Enterobacter cloacae, an enzyme involved in the biosynthesis of the plant hormone indole-3-acetic acid doc

Báo cáo khoa học

... cofactor to the surface of the protein. The entrance of the active site cleft is covered by the C-terminalhelix and this part of the polypeptide chain must move in order to allow entry of the substrate. ... with most residuesat the interface coming from the PYR and PP domains. This is in agreement with the average mobility of the domains in the crystal; the PYR domain has the lowest average B-factor,23 ... presence of DNA-bindingproteins involved in regulation of the gene expression of indole-3-pyruvic acid decarboxylase, a key enzyme in indole-3-acetic acidbiosynthesis in Azospirillum lipoferum...
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Báo cáo khoa học: Evaluation of potential regulatory elements identi®ed as DNase I hypersensitive sites in the CFTR gene doc

Báo cáo khoa học: Evaluation of potential regulatory elements identi®ed as DNase I hypersensitive sites in the CFTR gene doc

Báo cáo khoa học

... detect. Onedisadvantage of analysing carcinoma cell lines is that some of the DHS we observe may be the result of these linesshowing aberrant gene expression following tumorigenesis,rather than ... 17 are of similar intensity but the DHS in intron 18 is less evident ( Fig. 5B). In contrast, the DHS in intron 18 is more prominent than those in introns 16 and 17 (Fig. 5A) in chromatin from ... would be of the sameheight. F or both panels A and B the increasing amounts o fDNase show a proportionate increase in the intensity of the DHS fragments in the control samples. In Fig. 7A the forskolin-treated...
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Báo cáo khoa học: Isolation of a putative peroxidase, a target for factors controlling foot-formation in the coelenterate hydra docx

Báo cáo khoa học: Isolation of a putative peroxidase, a target for factors controlling foot-formation in the coelenterate hydra docx

Báo cáo khoa học

... after 35 min by four or five washes of the gel in H2O. The arrows indicate the stained bands in the gel. I is the majorperoxidase activity of hydra residing in the foot of the animal, IIindicates ... peroxidase containing cells lying in the ectoderm of the foot. The diaminobenzidine-stained granules are localized mainly in the apical part of the foot mucous cells asindicated by the arrow in (B). ... because the expression of this clone is restrictedto the ectoderm of the foot of hydra. In addition, we couldshow that the timing of the reappearance of ppod1transcripts in foot-regenerating tissue...
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Chronicles of a Dallas Cowboys Fan: Growing Up With America''''s Team in the 1960''''s by John Eisenberg pptx

Chronicles of a Dallas Cowboys Fan: Growing Up With America''''s Team in the 1960''''s by John Eisenberg pptx

Tiếp thị - Bán hàng

... was the youngest, the baby of the entire family. My father, Seymour Eisenberg, a doctor who was then the chief of medicine at the Dallas Veterans Administration Hospital, began taking me to the ... penalty wiping out the score and awarding the Steelers a safety that provided the difference in the game. (After that season, the NFL reduced the penalty for holding in the end zone from points to ... for the Washington Post. He had grown up in Baltimore in the 1950s, cheering for Johnny Unitas and the Colts with his dad. His book was a lovely reminiscence of that team, that time and his...
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Báo cáo khoa học: Catalytic mechanism of the primary human prostaglandin F2asynthase, aldo-keto reductase 1B1 – prostaglandin D2 synthase activity in the absence of NADP(H) pptx

Báo cáo khoa học: Catalytic mechanism of the primary human prostaglandin F2asynthase, aldo-keto reductase 1B1 – prostaglandin D2 synthase activity in the absence of NADP(H) pptx

Báo cáo khoa học

... schematically in Fig. 5. In the absence of NADPH, the concerted reaction of Asp43, Lys77 andHis110 increases the basicity of His110 and extracts the proton C11 of PGH2. Another proton is providedto the ... as the (a ⁄ b)8-barrel fold [3–6]. The nucleotidecofactor binds in an extended conformation at the top of the a ⁄ b-barrel, with the nicotinamide ring projectingdown into the center of the ... the overallthree-dimensional structure of the cofactor-binding sitewithin the catalytic pocket.DiscussionCatalytic mechanism of PGDS and PGFSactivities of AKR1B1Mutational analysis of the...
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state university of new york press after authority war peace and global politics in the 21st century mar 2000

state university of new york press after authority war peace and global politics in the 21st century mar 2000

Cao đẳng - Đại học

... replacement of “traditional forms of discipline associated with the family and the school” with “market discipline” (1995:26; see alsoDrainville, 1995). In this way, the workers of the world of the ... billion, if The Worries of Nations25was another. The political upheavals of the 1960s had their origins in the extension of American national interest to all parts of the globeduring the 1940s ... is that most of the others have it wrong. That the world is changing is doubted by onlya few; how and why it is changing, and what is its trajectory, is hardlyclear to anyone. The approach of...
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Báo cáo sinh học:

Báo cáo sinh học: " The Israeli strain IS-98-ST1 of West Nile virus as viral model for West Nile encephalitis in the Old World" pdf

Điện - Điện tử

... pathogenesis[5].Strains of WNV isolated in the United States were foundto be highly neuroinvasive in adult mice following intra-peritoneal (i.p.) inoculation[6]. In contrast of the investi-gations of the ... limited in its scope, the resultsindicate that WNV strain IS- 98-ST1 is suitable as viralmodel for West Nile encephalitis in the Old World. The Israeli strain IS- 98-ST1 that caused the epizootic in ... Madagascar island) and the lineage I (tropicalafrican strains) that caused the outbreaks of WNV infec-tion in North Africa, Europe, Israel, and in the United States. Nucleotide sequencing revealed that...
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Báo cáo hóa học:

Báo cáo hóa học: "Effect of montelukast on platelet activating factor- and tachykinin induced mucus secretion in the rat" doc

Hóa học - Dầu khí

... tachyki-nins. These findings may contribute to the beneficialeffect of montelukast in the treatment of bronchialasthma.Competing interests The author(s) declare that they have no competing inter-ests.Authors' ... tachykinin induced secretory activ-ity in the airways has never been evaluated. Therefore, itwas the aim of this study to investigate the effects of mon-telukast on PAF- and tachykinin induced ... notinfluence the neurokinin A induced increase of trachealsecretion (neurokinin A + montelukast: 127 ± 9%). The effect of montelukast on neurokinin B induced trachealmucus secretion is presented in figure...
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báo cáo hóa học:

báo cáo hóa học: " The effects of a graduated aerobic exercise programme on cardiovascular disease risk factors in the NHS workplace: a randomised controlled trial" pdf

Hóa học - Dầu khí

... recorded at 1-minute intervals. On the initial test this was used with VO2 data to determine the heart rate training intensity (65 % VO2 peak) of the exercise-training programme. This procedure ... further progression of the exercisetraining programme was provided, and participants wereinstructed to maintain the exercise as of week 8 for the final4 weeks. This was to evaluate if there ... In view of the 70% completion of the 16 sessions, and the significantimprovement in absolute 4minVO2 (-7 %), it appearsprobable that the intensity of the exercise performedwithin this time...
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