the iron factor in bone development
báo cáo hóa học:" High correlation of the proteome patterns in bone marrow and peripheral blood blast cells in patients with acute myeloid leukemia" pot
... some differences in the protein patterns but overall, these changes were small: Seven proteins (with two variants) were clearly defined in the gastric carcinoma cell line but not in the AML samples ... electrophoresis, the gels were fixed in 50% ethanol, and 10% acetic acid for 12 hours Silver staining Proteins were visualized using the silver staining method employing a modification of the method ... 15 minutes, followed by 300 V for 30 minutes and finally with 400 V for 60 minutes After IE-focusing, the sample was added on the cathodic side of the tube gel The aliquot of the sample contained...
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Báo cáo sinh học: "The THO complex as a key mRNP biogenesis factor in development and cell differentiation" potx
... the involvement of THO in mRNA 3’ end processing, whether or not direct, and by the identification in yeast THO mutants of a larger nuclear macromolecular structure containing components of the ... reconstituting potential The transfer of normal bone marrow cells rescued 70% of the mice from death The data [2] support the hypothesis that THOC5 is critical in bone marrow and in hemato poiesis, ... would be interesting to know whether the subunits of the THO complex have different roles in the differentiation of distinct cell types And it would certainly be important to understand how the role...
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Development of the Microfinance system in Russia
... Networking; The ACC foundation initiated in 2002; Aims at facilitating Russian businesses’ development through international cooperation and promotion, in the APEC region especially; Building ... out, leading to the mature creation MFIs Development Perspectives SMEs meet depositors directly attracting resources from financial institutions reinvestments the National Business Incubator ... in such tax conditions, which put them in less favorable conditions than banks Last achievements in the sphere of Microloans In 2000-2002: banks increased the intensiveness and volumes of the...
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Overview of the Capital Markets in Vietnamand Directions for Development
... (STC), indicating the potential of the market to grow Trading in the unofficial, over -the- counter market exceeds the official trading on Ho Chi Minh Securities Trading Center, the main trading market, ... seriously planning their investment in the financial sector 131 The Government is recommended to forge a vision on the evolution of the financial sector as well as its environment In doing so, the Government ... relationship with the central bank and the ministry The IMF has been recommending the Government to substantially review the SBV and Credit Institutions Laws Since the SSC was merged into the MOF in February...
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Tài liệu Accelerating Reproductive and Child Health Program Development: The Navrongo Initiative in Ghana docx
... to 108 in 1998, it rose again to 111 in 2003 In the Upper East Region, however, progress achieved in the 1980s and 1990s continued According to the 2003 GDHS, the infant mortality rate in this ... support Whereas community liaison in the CHO dimension focused on starting the program, liaison in the zurugelu arm was continuous, involving regular community gatherings, male volunteers, community-network ... associated with a dramatic decline in contraceptive use and an increase in the total fertility rate of 0.5 births occurring nine months following the interruption The dependency of couples on reliable...
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Tài liệu Báo cáo khoa học: Neuronal growth-inhibitory factor (metallothionein-3): evaluation of the biological function of growth-inhibitory factor in the injured and neurodegenerative brain pdf
... growth-inhibitory properties of GIF in AD There have been extensive studies examining the role of GIF in AD, linked to its initial discovery as a factor deficient in the AD brain There remains no ... explaining the vast neuronal loss in the AD brain Further investigation of the increased neurotrophic activity of the AD brain revealed that it correlated with the loss of a specific neuroinhibitory ... zinc in their axon terminals [7] In addition, the synthesis of GIF within cultured cells led to a significant increase in intracellular Zn(II) stores within those cells [7] GIF, through its zinc-binding...
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Tài liệu SICK WATER? THE CENTRAL ROLE OF WASTEWATER MANAGEMENT IN SUSTAINABLE DEVELOPMENT pdf
... filtration, and increases the groundwater contamination 38 Figure 13: Mining effects on rainfall drainage Acid Mine Drainage (AMD) is the number one environmental problem facing the mining industry ... brine into the receiving waters Temperature and salinity are two factors that determine the composition and distribution of species in the marine environment affecting water density and causing ... and hygiene There are approximately 600 000 residents living in the Kibera slums on the outskirts of Nairobi The term “flying toilet” originated in Kibera The flying toilet is a polythene bag that...
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Tài liệu Báo cáo khoa học: Coordination chemistry of iron(III)±porphyrin±antibody complexes In¯uence on the peroxidase activity of the axial coordination of an imidazole on the iron atom ppt
... face of the porphyrin and, in the more favorable conformation, H2O2 binds to the iron on the same face of the porphyrin as the catalytic COOH residue, the imidazole binding to the iron on the opposite ... hydrophobic binding pocket of the antibody than the binding of the second one, most probably because of the steric hindrance brought by the protein around the iron atom of the porphyrin Binding of monosubstituted ... the iron of free Fe(ToCPP) In addition, the in uence of the nature of the substituent was different in both cases In the case of Fe(ToCPP), it did not cause any steric hindrance for the binding...
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Tài liệu Báo cáo khoa học: Cell surface heparan sulfate proteoglycans Target and partners of the basic ®broblast growth factor in rat Sertoli cells pptx
... age The bFGF binding requires speci®c motifs on highly sulfated HS chains Sodium chlorate, in inducing structural alteration of HS chains, prevents the bFGF binding Our results indicate that the ... extraction, cells were incubated for 24 h either in the absence or in presence of FSH, dbcAMP, cholera toxin or bFGF, either in combination with FSH or dbcAMP or cholera toxin and bFGF Extraction ... [51±54] Inhibitory transcription factors that bind to AP-1 or FIN-1 or that inactive binding or transactivation capacity of, for example, FIN-1 and USF-1, could explain activation or inhibition...
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Báo cáo khoa học: Neural retina leucine-zipper regulates the expression of Ppp2r5c, the regulatory subunit of protein phosphatase 2A, in photoreceptor development pdf
... with the patterns of binding of Nrl to the rhodopsin promoter (Fig 4C,D) The mRNA transcript levels of Ppp2r5c and rhodopsin in mouse retina corresponded to the observed increase in Nrl binding ... analyzed with a motif searching program to identify binding sites of transcription factors Consensus binding sites are underlined, the Nrl-binding site is printed in bold, and the transcription start ... during photoreceptor development We next conducted a chromatin immunoprecipitation (ChIP) assay with HT22 cells, to further examine the binding of Nrl to the Ppp2r5c promoter in vivo Nrl binding...
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The Role of Small and Large Businesses in Economic Development doc
... and income generated directly by the firm—would certainly suggest this to be the case In reality, however, it is often the effects on other firms in the area the indirect effects—that carry the ... misleading to measure net employment changes as total employment in a size class at the end of the year less total employment in the size class at the beginning of the year The numbers presented in ... of the largest firms operate in industries in which only a few firms operate or dominate the market For the most part, these firms not compete with one another on the basis of price, but rather...
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Báo cáo khoa học: Two overlapping antiparallel genes encoding the iron regulator DmdR1 and the Adm proteins control sidephore and antibiotic biosynthesis in Streptomyces coelicolor A3(2) pdf
... in the TAdmdR1 mutant, suggesting that lack of DmdR1 in this mutant reduces synthesis of the Adm protein A putative DmdR1binding sequence (iron box) has been found in the upstream region of the ... lM iron (right) Formation of desferrioxamines is absent in the DdmdR1 ⁄ adm mutant and is inhibited by iron addition in all strains except in TAdmdR1, which lacks the DmdR1 iron regulator The ... TAdmdR1 in R5 or TBO solid media was still intense, in contrast to the results for MS medium, in which the pigmentation was much lower Actinorhodin and undecylprodigiosin production in these strains...
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Báo cáo khoa học: Insulin induces heme oxygenase-1 through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in renal cells pptx
... administered to establish the role of protein synthesis in insulin-induced HO-1 expression (Fig 2B,C) CHX abrogated HO-1 protein induction following insulin treatment but, in agreement with other ... role in HO-1 regulation in some models, but not in others 2350 During our investigation we studied a number of different transcription factors that may be involved in mediating the effect of insulin ... RH & Hellwig-Burgel T (2002) Normoxic induction of the hypoxia-inducible factor 1alpha by insulin and interleukin-1beta involves the phosphatidylinositol 3-kinase pathway FEBS Lett 512, 157–162...
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Feasibility Study – The critical success factor in project management pot
... Detailed Feasibility Study ( F/S) • Business Plan : for short term • F/S is for long term including engineering design • F/S includes Project Execution Plan 13 III Outline of F/S • Cover sheet • Content ... proceed the F/S by ourselves • - Who is good consultant ? Operated in many years or had many consultant contracts Professional in consultant ( mainly doing consultant work) Having good experts in ... PetroVietnam, EVN, Vinacomin, VNPT, etc Group C : usually decided by medium enterprises Each kind of project have different stages in development and implementation 10 Preparation for investment Implementation...
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Báo cáo khoa học: Analysis of the regulatory motifs in eukaryotic initiation factor 4E-binding protein 1 pot
... other features contribute to raptor binding We have not therefore attempted to define further the features in the C-terminus of 4E-BP1 that are involved in its binding to raptor The data for the ... mutating the proline to alanine (to give the RAIA mutant) causes a defect in the basal and insulin-stimulated phosphorylation of 4E-BP1 [25] We also tested the proline to valine mutation in wild-type ... positions (phenylalanine or leucine in the first position, and methionine, isoleucine or probably similar residues in the third) The requirements at the other positions are less strict: in the second and...
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Báo cáo khoa học: Transcriptional regulation of the desferrioxamine gene cluster of Streptomyces coelicolor is mediated by binding of DmdR1 to an iron box in the promoter of the desA gene doc
... interesting that the )10 sequence is located inside the iron box of desA (nucleotides 7–12 of the iron box), explaining the regulation of desA expression by binding of DmdR1 to the iron box The same ... start point is indicated as +1 (bent arrow) The1 9-bp palindromic region, which contains the repressor-binding site, is boxed, and the ribosome-binding site is underlined The ATG is shown in bold ... the biosynthesis of desferrioxamine B in S pilosus indicated that the first step in the desferrioxamine biosynthesis is the decarboxylation of lysine by a lysine decarboxylase encoded by the desA...
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Báo cáo khoa học: Bridging the gap between in silico and cell-based analysis of the nuclear factor-jB signaling pathway by in vitro studies of IKK2 ppt
... observed in the untreated cell population In order to shed light on the cause of this result, we carried out an in silico analysis by incorporating the inhibition kinetics within the existing computational ... to the inhibitor were slight, amounting to a modest reduction in amplitude and a delay in the rst oscillatory peak It is interesting to speculate on the failure of the inhibitor to eliminate the ... a is the ratio of apparent dissociation constants for binding GST-IjBa in the presence and absence of ATP, and the value of a indicates whether the binding of one substrate (ATP) affects the afnity...
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Báo cáo khóa học: Nerve growth factor mediates activation of the Smad pathway in PC12 cells doc
... implicated in multiple interdependent signals between pathways originating from receptor serine/threonine kinases and receptor tyrosine kinases Cellular responses induced by bone morphogenetic protein ... performed using LipofectAMINETM (Life Technologies Inc.) according to the manufacturer’s protocol 293T cells were maintained in minimum Eagle’s medium (MEM) containing 10% (v/v) fetal bovine serum ... signaling cascades originating from other receptor systems are involved in modulating Smad signaling [14,27,30,51,52] In the present work, we demonstrate that in PC12 cells NGFstimulated signaling...
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Báo cáo khoa học: " The Signal System in Interlingua — A Factor in Mechanical Translation" potx
... allusion and define the task of the researcher in mechanical translation as amounting to the elabo- Signal System in Interlingua ration of a system whereby all the elements appearing in the finished ... translation interconnecting German, French, English or other languages not including Interlingua Let us use for this purpose the English text on which the above-used Interlingua passage was based The Interlingua ... ('mice' instead of 'mouses') and the use of the lonely personal ending in the third person of the present tense; and finally it will point out as the only major weakness of the translation the unEnglish...
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Tìm thêm: xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn đặc tuyến hiệu suất h fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ chỉ tiêu chất lượng 9 tr 25