the hen and egg problem of cdids—who startsthe disease
Is there information in financial analysts forecasts about firms that subsequently restate their earnings
... properties of the analyst forecasts: the forecast error, the forecast dispersion and the skewness of the forecast distribution The earnings forecast studied hereof is the current-year forecast for the ... reflect the true financial performance of the restatement firms in the misstated period? To so, we examine the difference in the FAF of restatement and non-restatement firms for the period that the ... properties of the FAF are evaluated: the forecast error, the forecast dispersion and the skewness of the forecast distribution Thirdly, does the market have aggregate wisdom about the circumstances...
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Tài liệu Báo cáo khoa học: "The Structure of User-Adviser Dialogues: Is there Method in their Madness?" pdf
... model of what the novice user knows about the task The verbal interaction between the user and the adviser is not just one of execution of plans and recognition of plans but rather one of situated ... about the nature of dialogue structures, about the validity and usefulness of the concept of a dialogue structure, about the role of the task structure in determining dialogue structure, and in the ... consisting of the statement of a plan or of a goal, the subdialogue would be "inserted" in the task structure at the location of the plan described Another obvious clue is the presence of reliable...
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báo cáo hóa học:" CRP identifies homeostatic immune oscillations in cancer patients: a potential treatment targeting tool?" pdf
... taken in the weeks around the time of each dose (vaccine or chemotherapy), and then used to identify the position on the oscillating Page of (page number not for citation purposes) Journal of Translational ... ease on the one 'stylised' CRP curve Values are position on the CRP curve measured at the time of each chemotherapy dose, in the same patient (Adelaide) CRP Oscillation and Other Diseases Further ... to produce the up-swing in CRP dom application On the basis of preliminary evidence, we hypothesise that the current random application of chemotherapy (or other immuno-cytotoxic therapy) with...
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báo cáo hóa học: " Quality of life data as prognostic indicators of survival in cancer patients: an overview of the literature from 1982 to 2008" pot
... contribute to the initiation of morbidity, the biology of the disease appears to predominate, overriding the potential influence of life-style and psychosocial variables once the disease process ... exclusion of duplicates, the abstracts of all citations were reviewed Of these, 104 citations concerning the relationship between quality of life and survival were found to be relevant and were further ... picture of the patient's prognostic profile, hence possibly further improving accuracy of prognosis and making more tailored treatment decisions' [10] In addition, since lengthening survival of many...
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báo cáo hóa học:" Pain in cancer. An outcome research project to evaluate the epidemiology, the quality and the effects of pain treatment in cancer patients" pptx
... strategies Member of the Boards http://www.hqlo.com/content/4/1/7 highlighted the lack of and the need for new empirical evidence about the epidemiology and the effectiveness of available therapeutic ... conduct and supervision In order to be able to conduct and monitor the progress of the trial for the patients' safety and according to the World Medical Association Declaration of Helsinki and the ... estimated The propensity score method implies a comprehensive collection of information known to be causally associated with the choice of the treatments, then the production of a propensity score (the...
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Báo cáo khoa học: "Ultrasound-guided central venous catheterization in cancer patients improves the success rate of cannulation and reduces mechanical complications: A prospective observational study of 1,978 consecutive catheterizations" pps
... allowed the completion of the therapeutic program for 1,930/ 1,978 (97.6%) of the catheters inserted The absence of pneumotorax and other major complications indicates that US guidance should be mandatory ... at the point of insertion of the sternocleidomastoid muscle into the clavicular; the correct introduction of the needle was always confirmed by ultrasound guidance and by the easy aspiration of ... (DVT) and lifespan of the CVC Materials and methods Adult patients with hematologic and solid tumors admitted to the oncology-hematology department of the hospital of Piacenza, North Italy, and...
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Báo cáo khoa học: "Perioperative immune responses in cancer patients undergoing digestive surgeries" pptx
... interests The authors declare that they have no competing interests Authors' contributions MI was involved in the design of the study and writing of the manuscript MN and NH assembled the data TM and ... cells were not seen other than the reduction on POD in the hepatic resection group found On the other hand, there were also no significant differences in the percentage of CD4+IL-6+ T cells among ... defect of T cells to proliferate and to secrete cytokines characteristic of both Th1 and Th2 phenotypes They also reported that during the late postoperative course (day 5), production of IL-2 and...
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Báo cáo khoa học: " Linkage disequilibrium pattern of the ATM gene in breast cancer patients and controls; association of SNPs and haplotypes to radio-sensitivity and post-lumpectomy local recurrence" doc
... protective effect of the A allele The contradictory between our study and that of [28] may be a consequence of the different ethnicity of the populations or possibly a result of the limited study ... Figure illustration of the ATM gene Schematic Schematic illustration of the ATM gene The distribution of the variations detected in the studied materials along the gene is shown in the upper panel ... VNK and ALBD designed the study - TT, LJ and PV genotyped the samples from the American Breast cancer patients - LJ and PV genotyped the samples from the Norwegian breast cancer patients and the...
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báo cáo khoa học: "The potential benefits of low-molecular-weight heparins in cancer patients" ppsx
... The principal role of the antithrombotics in surgical patients is to provide effective anticoagulation over the course of the increased risk of VTE (during and postsurgery) with the minimum of ... understand this effect, and the potential role of the LMWHs as antineoplastic therapy Acknowledgements The author received editorial support in the preparation of this manuscript, funded by sanofi-aventis, ... impairment, and pregnant women [68] However, in the majority of patients, the pharmacokinetic advantages of the LMWHs mean they can be effectively administered without the need to monitor the anticoagulant...
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Báo cáo y học: "Is Phytalgic® a goldmine for osteoarthritis patients or is there something fishy about this nutraceutical? A summary of findings and risk-of-bias assessment" pot
... fishy taste in the mouth might certainly cause detection bias Assessment of the trial reporting in terms of risk of bias, the use of random assignment, and subsequent concealment of allocation ... interests The funding agencies (The Oak Foundation and The Danish Rheumatism Association) had no role in writing the report or in the decision to submit the manuscript for publication Neither of the ... the taste of fish oil during a 3-month trial, probably as difficult as it is to hide the taste of ginger [5] Finally, deviations from protocol and loss to follow-up often lead to the exclusion of...
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Báo cáo khoa học: "Performance of six severity-of-illness scores in cancer patients requiring admission to the intensive care unit: a prospective observational study" pot
... identified during assessment of the extent of their cancer and/ or consideration of the therapeutic options This assessment is conducted as soon as is possible, and end -of- life care is started if ... compare the performances of the CMM and of the general prognostic scores, all scheduled surgical patients were excluded, and therefore 542 (43.1%) patients were included in this analysis A total of ... 76% died in the hospital [33] In the present cohort about 37% of patients received MV Whether studying the entire population or the subgroup of nonscheduled surgical patients, all of the general...
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Báo cáo y học: "Clinical review: Specific aspects of acute renal failure in cancer patients" pot
... LM, Hensley ML, Meropol NJ, Winer EP, American Society of Clinical Oncology Chemotherapy and Radiotherapy Expert Panel: 2002 update of recommendations for the use of chemotherapy and radiotherapy ... the first few days, when the collecting system is encased in retroperitoneal fibrosis or tumour or when the obstruction is partial [24] The relief of the obstruction, either by percutaneous nephrostomy ... is the cornerstone of treatment Renal recovery depends on the severity and duration of the obstruction [24] Thrombotic microangiopathy The association between thrombotic microangiopathy (TMA) and...
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Báo cáo khoa học: "N-terminal pro-brain natriuretic peptide as an early prognostic factor in cancer patients developing septic shock" pdf
... analyzed the data and reviewed and coordinated the study AS and MF collected and analyzed the data J-PB, J-LB, DB, and CF reviewed and coordinated the study All authors read and approved the final manuscript ... under the curve, 0.87; p < 0.0001) summarizes the capacity of NTproBNP as a valuable predictor of mortality of patients with septic shock In the survivors and during the first three days of ICU ... factors by the univariate analysis (cutoff p < 0.05) To avoid increasing the risk of collinearity for the same variables measured at days and (LOD and NT-proBNP), we decided to include only the most...
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Báo cáo y học: " C-reactive protein in critically ill cancer patients with sepsis: influence of neutropenia" doc
... Francisco Xavier Hospital PP is Professor of Medicine of the Faculty of Medical Sciences from the New University of Lisbon, Portugal VCSD is assistant physician of the ICU of the Instituto Nacional de ... authors read and approved the final version of the manuscript 15 Authors’ information PP is coordinator of the Polyvalent Intensive Care Unit and president of the Antibiotic Commission of São Francisco ... elevations, and that this was particularly significant in the presence of neutropenia • The CRP course during the first week of antibiotic therapy was not influenced by the presence or absence of neutropenia...
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báo cáo khoa học: "Magnitude of risks and benefits of the addition of bevacizumab to chemotherapy for advanced breast cancer patients: Meta-regression analysis of randomized trials" ppt
... bevacizumab to chemotherapy for advanced breast cancer strengthen the need of a deep analysis of the correlation between adverse events and deaths on one side, and the maximization of the efficacy by ... This amount of benefit well compares with the benefits of other important therapeutic choices such as the addition of taxanes for the st line treatment of metastatic breast cancer, where the advantage ... PFS of and months, respectively The authors indicated that OS represents a reasonable primary endpoint when the SPP is short, while when the SPP is long, that dilutes the variability of the OS,...
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The NR4A orphan nuclear receptors are target genes of the novel drug c1 in cancer cells and potential mediators of drug induced apoptosis
... Pervaiz, Professor, Department of Physiology, Yong Loo Lin School of Medicine, NUS Their encouragement and guidance and their critique has been of paramount importance in directing the course of the ... Accordingly, the great and urgent need presently is to investigate the role of each of the plenitude of genes and proteins important in the progression of cancer NUCLEAR RECEPTORS The nuclear ... characterize the different transcription factors and pathways they induce for a comprehensive account of the mechanism of drug action The present study was designed to decipher the mechanism of C1 mediated...
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The Retinoblastoma Gene Family in Cell Cycle Regulation and Suppression of Tumorigenesis
... oncogenic potential of loss of Rb is likely to be decided by the expression of each of the Rb family members and the role these family members play in the differentiation of the cell type involved ... RasV12 , even in the absence of p16Ink4a and p19Arf Inactivation of either p21CIP1 or inactivation of the pocket protein family by expression of HPV-E7 restored the immortalization and RasV12 -mediated ... that in this assay loss of the Rb gene family is sufficient to allow oncogenic transformation On the other hand, in view of the lack of anchorage-independent growth of these cells, it remains...
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báo cáo khoa học: "Chemoradiotherapy followed by surgery versus surgery alone in esophageal cancer patients: is it time for additional evidence?" doc
... Goldberg R, Kiel K, Willett C, Sugarbaker D, Mayer R: Phase III trial of trimodality therapy with cisplatin, fluorouracil, radiotherapy, and surgery compared with surgery alone for esophageal cancer: ... Guindi M, Hornby J, Xu W, Ringash J, Keshavjee S, Chen E, Haider M, Darling G: Phase trial of preoperative irinotecan plus cisplatin and conformal radiotherapy, followed by surgery for esophageal cancer ... Gastro-Intestinal Trials Group: Surgery alone versus chemoradiotherapy followed by surgery for resectable cancer of the oesophagus: a randomised controlled phase III trial Lancet Oncol 2005, 6:659-668...
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Báo cáo khoa học: "Postmastectomy irradiation in breast in breast cancer patients with T1-2 and 1-3 positive axillary lymph nodes: Is there a role for radiation therapy" ppsx
... (42%) Five of them developed bone metastasis first and liver metastasis subsequently Two Table The distribution of recurrences and survivals in radiotherapy and no-radiotherapy group Radiotherapy ... some of them have one or more predictor and prognostic factors for failure It appears that the benefit of RT is worth of the risk of treatment morbidity with accurate selection PMRT for T1-2 and ... Follow-up The patients were followed with office visits and physical examinations every months for the first years, every months for the fourth and fifth years, and annually after years Chest X-ray and...
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báo cáo hóa học:" Comparative study on the immunogenicity between an HLA-A24-restricted cytotoxic T-cell epitope derived from survivin and that from its splice variant survivin-2B in oral cancer patients" pot
... the design of the study and performed the evaluation of the data TT helped to draft the manuscript SI contributed to the HLA-A24-binding assay and CTL induction from PBMCs AM, AY and HH contributed ... patients' samples with the informed consent HH and NS contributed to the design and coordination of this study as well as reviewing the manuscript All authors have read and approved the final manuscript ... grant-aid from Ministry of Education, Culture, Sports, Science and Technology of Japan and a grant-aid for Clinical Cancer Research from the Ministry of Health, Labor and Welfare of Japan References...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008