the half life of glutathione
Báo cáo y học: " Introduction of an agent-based multi-scale modular architecture for dynamic knowledge representation of acute inflammation" ppt
... nature of the "scale-up" translation in these models, they capture and instantiate the "essence" of specific pathophysiological hypotheses The test of plausibility of these hypotheses (and note, the ... instantiation of the hypothesis linking the gut to the lung in the pathophysiology of MOF [21-23] The qualitative nature of the latter two model levels is acknowledged However, I wish to note that these ... Screen shot of the Graphical User Interface of the EBABM Screen shot of the Graphical User Interface of the EBABM Control buttons are on the Left; Graphical Output of the simulation is in the center...
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Báo cáo y học: "The instantaneous helical axis of the subtalar and talocrural joints: a non-invasive in vivo dynamic study" ppsx
... definition of the FHA for either joint As described by Woltring and colleagues [24], the FHA is only fully defined when: the three-dimensional direction of the FHA (n), the three-dimensional location of ... base plate extending to the mid-calcaneus The ball of the foot rested on the foot pedal of the ALD Plastic stops were placed in the ALD to limit foot-pedal rotation such that the subject's motion ... in calcaneal-tibial PF The use of a cam resulted in a fixed moment arm from the rope to the center of rotation of the ALD (Figure 1) The loading level was selected as the level at which all subjects...
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Báo cáo y học: " Monitoring the initial pulmonary absorption of two different beclomethasone dipropionate aerosols employing a human lung reperfusion model" potx
... the compound in the therapeutic target tissue The dose and the percentage of lung deposition as well as the specific receptor binding affinity determine the therapeutic efficacy of the corticosteroid ... height of the plasma containing chamber MW Molecular weight of the compound r Inner radius of the plasma containing chamber VP Calculated volume of plasma in the dialysis unit On basis of the calculated ... evaporation of the propellant To get an impression of the process of dissolution of these BDP particles in human bronchial fluid the Sanasthmax®/ Becloforte™ device was actuated and the glucocorticoid...
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Guidelines on the diagnosis and management of acute pulmonary embolism pot
... significance in PE Many of them are related to the pre-existing condition and the comorbidities of the individual patient rather than to the severity of the index PE episode For example, in the ICOPER registry, ... scintigraphy results, the authors estimated the incidence of VTE in the city of Malmo at 42.5/10 000 inhabitants/year However, recalculation of their data indicates that the incidence of PE was 20.8/10 ... the risk of perioperative VTE The longer the duration of antithrombotic prophylaxis, the lower the incidence of VTE.5,9 Most patients with symptomatic DVT have proximal clots, and in 40–50% of...
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Improving the diagnosis and treatment of smear-negative pulmonary and extrapulmonary tuberculosis among adults and adolescents pdf
... skin into the centre of the node or at the point of maximum fluctuance, and pull back on the syringe piston If no aspirate is obtained, move the needle in and out of the centre of the node while ... Association and the Damien Foundation have also provided their comments on the earlier version The document was reviewed by members of the Core Group of the global TB/ HIV Working Group of the Stop TB ... facilities) based on the epidemiology of the HIV epidemic and the magnitude of HIV-associated tuberculosis, and develop appropriate guidance for the implementation of these recommendations The recommendations...
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Báo cáo Y học: The mitochondrial-lysosomal axis theory of aging Accumulation of damaged mitochondria as a result of imperfect autophagocytosis ppt
... features of aging A number of early explanations of aging, such as Orgel’s error catastrophe theory and the somatic mutation theory, were based on the idea that aging results from the accumulation of ... postmitotic cells, one of the most prominent signs of aging, has been known for more than 150 years [28] However, the relation of lipofuscin to lysosomes and the basic mechanisms of lipofuscin formation ... alterations and misfunction of these two organelles account for the majority of senescent changes in postmitotic cells INTRALYSOSOMAL ACCUMULATION OF LIPOFUSCIN Deposition of lipofuscin pigment within...
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Báo cáo sinh học: "Resveratrol prevents inflammation-dependent hepatic melanoma metastasis by inhibiting the secretion and effects of interleukin-18" potx
... understanding of its mechanisms of action and therefore, for a better assessment of its antitumor efficacy The experimental hepatic colonization of B16 melanoma (B16M) is a unique model for determining therapeutic ... enhanced Page of 11 proliferation [15] and increased adhesion to HSE via a VLA-4-dependent mechanism [17] In this study, we investigated the effect of RVL on the microvascular phase of the hepatic ... adhesion to those HSE [16] The pivotal position of H2O2 in this metastasis model was further supported by the fact that incubation of HSE cells with non-toxic concentrations of H2O2 also directly...
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báo cáo hóa học: " The minimal important difference of the hospital anxiety and depression scale in patients with chronic obstructive pulmonary disease" pot
... design of the study, collection of the data and revised the manuscript SB revised the manuscript HJS participated in the design of the study, performed the statistical analysis and revised the manuscript ... analysis where the instrument of interest is the dependent and the anchors the independent variable Using the equation one can estimate the minimal important difference of the instrument of interest ... the minimal important difference of the HADS it is not known[11] The concept of the minimal important difference the smallest difference in the outcome of interest that informed patients or their...
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báo cáo hóa học: " Development and validation of a preference based measure derived from the Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR) for use in cost utility analyses" doc
... candidates for exclusion However, it was the aim to include a reasonable spread of items in terms of the degree of severity they represented The logit severity of the selected items ranged from -1.25 ... that providing the descriptive system is valued on the same scale using the same variant of the same valuation technique, as was the case for the CAMPHOR and EQ-5D models, then the valuations ... according to the EQ-5D It is questionable whether any individuals with PH would consider themselves to have perfect health given the severe nature of the symptoms, the fact that the condition is often...
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báo cáo hóa học:" Negative impact of chronic obstructive pulmonary disease on the health-related quality of life of patients. Results of the EPIDEPOC study" docx
... worsening in their health-related quality of life (HRQoL) However, it has been confirmed that the evaluation alone of the severity of COPD, measured by the degree of reduction of the forced expiratory ... and diagnosed of COPD at least 12 months before the start of the study, were included The diagnosis of the disease was performed according to the criteria of the Spanish Society of Pneumology ... volume of sputum or any combination of these symptoms, of acute onset, and requiring a change in the regular medication of the patient [18] The study was approved by the Ethics Committee of the...
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Báo cáo sinh học: " Research Article Solutions of Linear Impulsive Differential Systems Bounded on the Entire Real Axis" ppt
... is the generalized Green operator 16 of the problem of finding bounded solutions where G γi of the impulsive system Proof Since P D PP − I −Q P Q P and DPD 0, we have P PD P DPD By virtue of Theorem ... Then we denote by P PD r an n × r matrix composed of a complete system of r linearly independent columns of the matrix P PD Thus, we have proved the following statement Theorem Assume that the ... formed by a complete system of r linearly independent solutions of homogeneous f problem and G γi t is the generalized Green operator of the problem of finding solutions of the impulsive problem bounded...
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Báo cáo y học: "Gene expression profiling in murine autoimmune arthritis during the initiation and progression of joint inflammation" pps
... from a total of four paws of two arthritic animals When the number of replicates is low and the distribution of data in the general population is basically unknown, the applicability of Student's ... any pair of the experimental conditions compared Irrespective of the statistics used (either unpaired Student's t-test, the Fisher exact test or the Mann–Whitney U-test), the number of differentially ... genes) phase of arthritis, are listed in the Additional files Although many of these differentially expressed genes, detected either in the acute phase or during the progression of the disease,...
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Báo cáo y học: "Longitudinal evaluation the pulmonary function of the pre and postoperative periods in the coronary artery bypass graft surgery of patients treated with a physiotherapy protocol" ppt
... [12] and the position of the drains [13] Pain due to thoracotomy is a limiting factor for mobility and breathing A high level of postoperative pain is common because of the cutting of the skin, ... and the study was approved by the institutional ethics committee (Resolution 196/96 of the National Health Council) The three groups were paired by age and gender The patients included in the ... contribute to decreased cough efficiency, which is the main mechanism for the elimination of secretions from the tracheobronchial tree due to the immobility of the thoracic wall This immobility causes...
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Báo cáo y học: "Acute pressure overload of the right ventricle. Comparison of two models of right-left shunt. Pulmonary artery to left atrium and right atrium to left atrium: experimental study" doc
... regarding the effects of a shunt not at the atrial level but from the pulmonary artery to the left atrium The purpose of this study was to examine the effects of right ventricle overload of two ... Picture of the pulmonary artery -left atrial shunt in the pig Results Hemodynamics The central venous pressure (mean), the mean pressure of left atrium, the cardiac output, the pressure of the distal ... concerning the percentage change from baseline to 10 minute of the pCO2 of the left atrium variable (p = 0.016) and the percentage change from baseline to 20 minute of the pCO2 of the left atrium...
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Báo cáo y học: "Proanthocyanidin to prevent formation of the reexpansion pulmonary edema" doc
... edema in rats with RPE In the process of RPE, two main contributing factors are; the amount of drained fluid or air, and the chronicity of the lung collapse There are other minor contributing factors ... measurement: The reaction mixture was 50 mMol tris buffer with pH 7.6; containing mMol of Na2 EDTA, mMol of reduced glutathione (GSH), 0.2 mMol of NADPH, mMol of sodium azide and 1000 U of glutathione ... capillary pressure of the lung, mechanical damage of alveoli due to abrupt distension, loss of surfactant, migration of inflammatory cells, release of inflammatory mediators, increase of cytokines...
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Báo cáo y học: "The Journal of Inflammation" docx
... about the complexity of the inflammatory response and the actions of the currently available drugs the value of particular clusters of targets becomes apparent However, the success of anti-TNFα therapy ... [8] Page of (page number not for citation purposes) Journal of Inflammation 2004, 1:1 The differential responsiveness to these, and other, therapeutic agents and, indeed, the induction of the inflammatory ... considered as the full Many of the drugs used in the treatment of inflammatory conditions, predate our current understanding of the biochemical processes involved in the disease Traditionally, the standard...
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Báo cáo y học: "The role of the purinergic P2X7 receptor in inflammation" pot
... level by the expression and activation of the Bcl-2 family of proteins and the components of the caspase pathways, which dictate the lifespan and mode of cell death in such cells [96] Importantly, ... detrimental to the host The putative role of the P2X7R in such processes is discussed below 3.1 P2X7R regulation of cytokine production in haemopoietic cells It has been clear since the cloning of the P2X7R ... P2X7R activation underlies some of the immunomodulatory effects of the human CHDP, LL-37 [38,40,41] LL-37 is the major active cleavage product of the only human cathelicidin hCAP18, is upregulated...
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Báo cáo y học: "Retention of foreign body in the gut can be a sign of congenital obstructive anomaly: a case report" potx
... loops ofpresence of ain the left Plain radiograph of the abdomen showing the metallic foreign body in the right lower quadrant, the presence of a 'double bubble sign', and a few dilated loops of ... performed after removal of the foreign object(s) However, in spite of the persistence of the radio-opaque foreign body on plain X-rays of the abdomen, the possibility of an obstructing anomaly ... thickening of their walls, and an annular pancreas was detected encircling the second part of the duodenum In addition, there was a membrane with a small aperture in the duodenum Surprisingly, the metallic...
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Báo cáo y học: " Oxidative modification of albumin in the parenchymal lung tissue of current smokers with chronic obstructive pulmonary disease" docx
... levels of carbonylated HSA were derived primarily from the lung or the systemic circulation Ultimately independent of the source of HSA, decreased levels of the protein, could contribute to the ... supports the role of antioxidant disturbances in the progression of COPD The data however can not indicate the time scale required for the resolution of smoking related oxidative stress within the ... HSA as a marker of oxidative stress in current smokers with COPD, but also the potential therapeutic role of HSA in the homeostasis of the oxidant/ anti-oxidant balance, where there is a large...
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Tìm thêm: xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25