the eukaryotic cell s genetic instructions are housed in the nucleus and carried out by the ribosomes
Báo cáo y học: " Newly described human polyomaviruses Merkel Cell, KI and WU are present in urban sewage and may represent potential environmental contaminants" potx
... procedures applied as well as of the presence of enzymatic inhibitors in the samples We processed the samples as separate batches at separate periods of time The samples showed typical levels of ... b The sequence positions are referred to strain EF127906 c The sequence positions are referred to strain EU375803 d The sequence positions are referred to strain K02562 a The others and from strain ... the new polyomaviruses because no cell culture systems for these viruses are available at present Furthermore, for other human polyomaviruses, such as JCPyV, the regulatory regions of strains...
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Tài liệu Báo cáo khoa học: Various secretory phospholipase A2 enzymes are expressed in rheumatoid arthritis and augment prostaglandin production in cultured synovial cells docx
... arrows) (C–E) Staining of sPLA2-V in three active RA tissues In all cases, intense staining of the granulation tissue in the sublining interstitium was evident Staining of the granulation tissue and ... synovial lining cells in the RA joints Distribution of sPLA2-V in the synovial sublining lesions (Fig 5) is noteworthy because this enzyme shows fibroblastic location in several other tissues (S Masuda, ... of these sPLA 2s in synovial tissues of RA patients by immunohistochemistry A previous immunohistochemical study showed that, in RA tissues, sPLA2-IIA is distributed in various cells, such as synovial...
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Báo cáo khoa học: Glutathione transferases kappa 1 and kappa 2 localize in peroxisomes and mitochondria, respectively, and are involved in lipid metabolism and respiration in Caenorhabditis elegans pot
... of the embryo Fluorescence was observed as strong punctate staining in intestinal cells and in the epidermis The number and intensity of fluorescent structures increased strongly in the intestine ... oxygen species The intestine is also a highly metabolically active organ and represents the tissue in which most C elegans peroxisomes are found, as shown by immunostaining for catalase [14] and by ... was weakly fluorescent (Fig 2H) Interestingly, similar staining has been observed previously by the expression of GFP fused to specific subcellular targeting sequences [11], strongly suggesting the...
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Báo cáo sinh học: " Roles of adjuvant and route of vaccination in antibody response and protection engendered by a synthetic matrix protein 2-based influenza A virus vaccine in the mouse" pdf
... titers, was tested in ELISA against M2e-MAP Gd40 (squares), Cys-M2e (triangles) and HeLa-M2 (circles) as described in the method section, using the same reagents and incubation times for each assay ... chains are expressed only by ~5% of Abs in the BALB/c mouse, they may be expressed at higher frequency in responses of some specificities We therefore tested selected serum samples for λ-positive ... immunization (as in A) attributed to the combined effects of strong local and systemic T and B cell responses against several viral proteins Since infection induces only a poor M2e-specific Ab response [13],...
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Báo cáo y học: " Induction of multiple matrix metalloproteinases in human dermal and synovial fibroblasts by Staphylococcus aureus: implications in the pathogenesis of septic arthritis and other soft tissue infections" pdf
... proteases Several matrix metalloproteinases (MMPs) are induced in host cells in response to infectious stimuli Normally, MMPs assist in clearing infections, initiating immune responses, and in tissue ... and Sar/Agr mutants of S aureus Blevins and colleagues [19] have shown that S aureus strains lacking the regulatory loci Sar or Agr result in less severe SA and osteomyelitis in murine models ... connective tissue cells such as fibroblasts, fibroblast-related cells, chondrocytes, neutrophils, and monocytes/macrophages in response to both infectious assaults and inflammatory cytokines such as TNF-α...
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báo cáo khoa học: " Changes in time-use and drug use by young adults in poor neighbourhoods of Greater Buenos Aires, Argentina, after the political transitions of 2001-2002: Results of a survey" potx
... confidence in these findings Another limitation is that the analyses only measured associations and therefore no causal relationship can be established Nonetheless, the following conclusions regarding ... decline Nevertheless, focusing on the country as a whole, there are signs of alienation and of a decrease in successful normative regulation of youth in studies conducted after the crises These include ... drugs people stopped sniffing cocaine (for at least the last 12 months) IDUs stopped injecting (no injection during the last 12 months) Table (bottom lines) shows the mean hours spent using drugs...
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Báo cáo khoa học: " Fasting and nutrient-stimulated plasma peptide-YY levels are elevated in critical illness and associated with feed intolerance: an observational, controlled study" ppt
... characteristics and in fasting and integrated (as assessed by area under the curve [AUC] from to 180 minutes) plasma PYY concentrations between critically ill and healthy subjects were assessed using Student 's ... the gastrointestinal tract to the central vascular system [40] Further studies are required to assess these associations, in particular whether the heightened PYY response to nutrients predisposes ... in its design and coordination, and helped to draft the manuscript NN and LB participated in the study design, carried out the studies and data and statistical analysis, and drafted the manuscript...
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Báo cáo khoa học: Two functionally redundant isoforms of Drosophila melanogaster eukaryotic initiation factor 4B are involved in cap-dependent translation, cell survival, and proliferation doc
... Extramitotic cells in the differentiated tissue, posterior to the morphogenetic furrow (arrows), are evident in the disc overexpressing eIF4B-L Asterisks indicate the two waves of mitotic cells Discs are ... developing tissues provided interesting insights into the function of eIF4B In mammalian cell cultures, a 50-fold overexpression of eIF4B resulted in the inhibition of the protein synthesis of ... luciferase synthesis obtained in the Dm-eIF4B-inhibited lysate was similar to that obtained in the noninhibited lysate Taken together, these results suggest that both Dm-eIF4B isoforms have a...
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Báo cáo khoa học: Protein folding and disulfide bond formation in the eukaryotic cell pptx
... role in this decision process [30] Upon binding to the surface of mammalian cells, ricin gains access to the cell s interior by retrograde transport The ricin A chain is retrotranslocated into the ... ER stress, and it will be interesting to see how similar technologies can be used to study stress foci in higher organisms, where the ER stress response is more complex [33a] Conclusions There ... miscreant proteins before giving up on them The unfolded protein response (UPR) is one such mechanism, whereby membrane-spanning stress sensors such as Ire1 detect unfolded proteins in the ER and facilitate...
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Báo cáo khoa học: Mitochondrial connection to the origin of the eukaryotic cell pdf
... characteristic insert It is lacking in ValRS of other prokaryotes and in isoleucyl-tRNA synthetase [18] Identical amino-acid residues are shaded, and conserved ones are in bold Two signatures showing the ... represented as a multifurcation Shown in the boxes are some key systems and processes related to hypothetical evolutionary events, and protein/gene data supporting these events Question marks indicate ... magnetotacticum apparently lacks the insert, and Rhodopseudomonas palustris has a five-amino-acid insert The number at the top refers to position in the Mesorhizobium loti sequence Accession numbers are placed...
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Báo cáo y học: "Indoleamine 2,3-dioxygenase-expressing dendritic cells are involved in the generation of CD4+CD25+ regulatory T cells in Peyer''''s patches in an orally tolerized, collagen-induced arthritis mouse model" ppt
... times were compared between the two groups using the nonparametric Mann–Whitney U test All data are expressed as the mean ± standard deviation Statistical analysis was performed using SPSS 10.0 ... mononuclear cells using the magnetic-activated cell sorting system The expression of IDO mRNA was analyzed using RT-PCR β2-Actin was used as an internal control Each value is the mean ± standard deviation ... that comprises the mucosal epithelium, lamina propria, Peyer 's patches, and mesenteric lymph nodes [1,2] Peyer 's patches are essential sites for the induction of mucosal immune responses and oral...
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Báo cáo y học: "B-lymphocyte stimulator/a proliferation-inducing ligand heterotrimers are elevated in the sera of patients with autoimmune disease and are neutralized by atacicept and B-cell maturation antigen-immunoglobulin" pdf
... BLyS The molecular mass of the heterotrimers was confirmed by SEC-MALS mass distribution LS/UV/RI 3-detector analysis Binding kinetics and affinity studies The binding affinities and kinetics ... levels and disease activity markers for patients with SLE A subset of the samples from patients with SLE used in the heterotrimer assay had previously been assessed for various markers of disease ... analysis JAG helped design the study and assisted with data analysis All authors read and approved the final manuscript Competing interests SRD, TRB, NBH, MM, and SP are current employees and stockholders...
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Báo cáo y học: "Comment on and reply to "Analysis of variation of amplitudes in cell cycle gene expression" by Liu, Gaido and Wolfinger: On the analysis of gene expression during the normal, eukaryotic, cell cycle" docx
... for themselves 7) The DNA distribution of cells should be narrow in the synchronized cells and these distributions should then reflect the movement of cells through the division cycle Thus, newborn ... determining something about cells For example, "different conditions" means growing cells in one case at 25°C and in another case at 37°C and seeing what happens to them or what is different in these ... are quite inconsistent with the proposal that the cells are synchronized The flow cytometric data on DNA contents during growth of the arrested cells shows the cells are not synchronized The DNA...
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Báo cáo y học: "Systems biology-defined NF-κB regulons, interacting signal pathways and networks are implicated in the malignant phenotype of head and neck cancer cell lines differing in p53 status" pps
... expression of gene subsets induced by TNF-α in UM-SCC cell lines The responsive kinetics of many of the novel NF-κB target genes are either slowly induced, or induced and sustained without rapid ... datasets of HNSCC (approximately 80% from tissue specimens) Preliminary analyses are consistent with key observations from this study using UM-SCC cell lines, including that the molecules in, and/ or ... that encodes TF j or the experiment results from NF-κB DNA binding assays (as described in the NF-κB DNA binding assay section) In our analysis, we compare the results based on these two different...
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the effects of teacher’s differentiated instructions based on students’ learning styles on their motivation = ảnh hưởng của việc đa dạng hóa phương pháp giảng dạy dựa trên phong cách học cá nhân đối với động lực học
... activities (suitable for students‟ readiness and interests), so that they can assign these activities in case some students claim “I‟m done” too soon in class These on-going activities can be ... purposes) and 3C (Test-taking skills) The preceding courses of those are 1A, 1B, 1C in first semester of the first year and 2A, 2B, 2C in the second half The sequencing courses are 4A, 4B and ... deep insight into the issue of learning styles, differentiated instructions and motivation Besides, another simultaneous consequence of this action research is to raise students‟ awareness of their...
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THE EFFECTS OF TEACHER’S DIFFERENTIATED INSTRUCTIONS BASED ON STUDENTS’ LEARNING STYLES ON THEIR MOTIVATION
... class The intent of differentiating instruction is to maximize each student 's growth and individual success by meeting each student where he or she is and assisting in the learning process (Hall, ... teacher-researcher self-observed herself in class This brought both advantages and disadvantages Observations in other kinds of research sometimes may come across some obstacles such as teacher s objection ... questions All the questions are in the form of open-ended ones so as to draw out the most information from the interviewees The interviews with students are undertaken to gather the data about the...
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INTERLEUKIN 6 RELEASE FROM t98g HUMAN GLIAL CELL LINE AS a PREDICTIVE MARKER FOR CHRONIC PAIN, AND THE CHARACTERIZATION OF SUBSTANCE(S) INVOLVED IN PAIN
... ventricles of the brain and the spinal cord, contains substances secreted from nerve cells, reflecting changes occurring in the CNS CSF analysis remains a key tool in understanding the status and ... within the nervous system, are involved in chronic pain transmission They are synthesized locally within the axon terminal Besides the common small molecule neurotransmitters such as serotonin, ... 1995) The nociceptive response was associated with the production of prostaglandins and was blocked by inhibitors of prostanoid synthesis In addition, COX inhibitors as well as prostaglandin receptor...
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Natural botanical products have a long history in the world and are featured in using a complex
... angiogenesis in the tumors Assessment of angiogenesis Microvessel density was assessed by immunostaining as described previously [11] with modifications Sections were digested with trypsin for 30 at room ... hydrogen-peroxidase-diaminobenzidine to visualize the microvessels The results of microvessel density were expressed as the number of microvessel per field (x 200) Assessment of apoptosis Epithelial cell ... by CK Life Sciences Limited (CKLS) Schisandra chinensis has been shown to suppress the TPA-induced skin tumor formation and prostate carcinogenesis [1, 2] It also aids to protect liver from injury,...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008